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Original Articles

An in vitro system for exposure of lung cells to gases: Effects of ozone on rat macrophages

Pages 115-126 | Received 31 Jul 1984, Accepted 10 Dec 1984, Published online: 20 Oct 2009

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Read on this site (4)

Christiaan B. Brink, Anita Pretorius, Barend P.J. van Niekerk, Douglas W. Oliver & Daniel P. Venter. (2008) Studies on cellular resilience and adaptation following acute and repetitive exposure to ozone in cultured human epithelial (HeLa) cells. Redox Report 13:2, pages 87-100.
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Patricia A. Weideman & Richard B. Schlesinger. (1994) Effect of in Vitro Exposure to Ozone on Eicosanoid Metabolism and Phagocytic Activity of Human and Rabbit Neutrophils. Inhalation Toxicology 6:1, pages 43-55.
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StephenE. Alpert, ConstanceM. Kramer, MichaelM. Hayes & PhyllisA. Dennery. (1990) Morphologic injury and lipid peroxidation in monolayer cultures of rabbit tracheal epithelium exposed in vitro to ozone. Journal of Toxicology and Environmental Health 30:4, pages 287-304.
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KevinE. Driscoll, ThomasA. Vollmuth & RichardB. Schlesinger. (1987) Acute and subchronic ozone inhalation in the rabbit: Response of alveolar macrophages. Journal of Toxicology and Environmental Health 21:1-2, pages 27-43.
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Articles from other publishers (34)

Concepción Salaberria, Carlos A. Chávez-Zichinelli, Isabel López-Rull, Marta C. Romano & Jorge E. Schondube. (2023) Physiological status of House Sparrows (Passer domesticus) along an ozone pollution gradient. Ecotoxicology 32:2, pages 261-272.
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Morton Lippmann. 2020. Environmental Toxicants. Environmental Toxicants 783 853 .
Morton Lippmann & George D. Leikauf. 2020. Environmental Toxicants. Environmental Toxicants 1 40 .
Faye F. Liu, Cheng Peng & Jack C. Ng. (2015) BTEX in vitro exposure tool using human lung cells: Trips and gains. Chemosphere 128, pages 321-326.
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Faye F. Liu, Cheng Peng, Beate I. Escher, Emmanuelle Fantino, Cindy Giles, Stephen Were, Lesley Duffy & Jack C. Ng. (2013) Hanging drop: An in vitro air toxic exposure model using human lung cells in 2D and 3D structures. Journal of Hazardous Materials 261, pages 701-710.
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James T. McCarthy, Edward Pelle, Kelly Dong, Krupa Brahmbhatt, Dan Yarosh & Nadine Pernodet. (2013) Effects of ozone in normal human epidermal keratinocytes. Experimental Dermatology 22:5, pages 360-361.
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V. Boxhammer, Y.F. Li, J. Köritzer, T. Shimizu, T. Maisch, H.M. Thomas, J. Schlegel, G.E. Morfill & J.L. Zimmermann. (2013) Investigation of the mutagenic potential of cold atmospheric plasma at bactericidal dosages. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 753:1, pages 23-28.
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Judy L. Oakes, Brian P. O’Connor, Laura A. Warg, Rachel Burton, Ashley Hock, Joan Loader, Daniel LaFlamme, Jian Jing, Lucy Hui, David A. Schwartz & Ivana V. Yang. (2013) Ozone Enhances Pulmonary Innate Immune Response to a Toll-Like Receptor–2 Agonist. American Journal of Respiratory Cell and Molecular Biology 48:1, pages 27-34.
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Zhuowei Li, Robert M. Tighe, Feifei Feng, Julie G. Ledford & John W. Hollingsworth. (2013) Genes of Innate Immunity and the Biological Response to Inhaled Ozone. Journal of Biochemical and Molecular Toxicology 27:1, pages 3-16.
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Mashael Al-Hegelan, Robert M. Tighe, Christian Castillo & John W. Hollingsworth. (2010) Ambient ozone and pulmonary innate immunity. Immunologic Research 49:1-3, pages 173-191.
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Farrukh Afaq, Mohammad Abu Zaid, Edward Pelle, Naghma Khan, Deeba N. Syed, Mary S. Matsui, Daniel Maes & Hasan Mukhtar. (2009) Aryl Hydrocarbon Receptor Is an Ozone Sensor in Human Skin. Journal of Investigative Dermatology 129:10, pages 2396-2403.
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Morton Lippmann. 2009. Environmental Toxicants. Environmental Toxicants 869 936 .
Morton Lippmann & George D. Leikauf. 2009. Environmental Toxicants. Environmental Toxicants 1 38 .
Michaela Aufderheide. (2008) An efficient approach to study the toxicological effects of complex mixtures. Experimental and Toxicologic Pathology 60:2-3, pages 163-180.
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G. Fischäder, C. Röder-Stolinski, G. Wichmann, K. Nieber & I. Lehmann. (2008) Release of MCP-1 and IL-8 from lung epithelial cells exposed to volatile organic compounds. Toxicology in Vitro 22:2, pages 359-366.
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John W. Hollingsworth, Shuichiro Maruoka, Zhuowei Li, Erin N. Potts, David M. Brass, Stavros Garantziotis, Alan Fong, W. Michael Foster & David A. Schwartz. (2007) Ambient Ozone Primes Pulmonary Innate Immunity in Mice. The Journal of Immunology 179:7, pages 4367-4375.
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Michaela Aufderheide. 2006. Cigarette Smoke and Oxidative Stress. Cigarette Smoke and Oxidative Stress 261 277 .
Michaela Aufderheide. (2005) Direct exposure methods for testing native atmospheres. Experimental and Toxicologic Pathology 57, pages 213-226.
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Branislava Janic, Todd M. Umstead, David S. Phelps & Joanna Floros. (2003) An in vitro cell model system for the study of the effects of ozone and other gaseous agents on phagocytic cells. Journal of Immunological Methods 272:1-2, pages 125-134.
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Philippe Laval-Gilly, Jaı̈ro Falla, Deborah Klestadt & Michel Henryon. (2000) A new approach to evaluate toxicity of gases on mobile cells in culture. Journal of Pharmacological and Toxicological Methods 44:3, pages 483-488.
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C.C. CARDOSO,J.C.T. CARVALHO, E.C. OVANDO, S.B. MACEDO, R. DALL'AGLIO & L.R. FERREIRA. (2000) ACTION OF OZONIZED WATER IN PRECLINICAL INFLAMMATORY MODELS. Pharmacological Research 42:1, pages 51-54.
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B Wallaert, O Fahy, A Tsicopoulos, Ph Gosset & A.B Tonnel. (2000) Experimental systems for mechanistic studies of toxicant induced lung inflammation. Toxicology Letters 112-113, pages 157-163.
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Lisa K. Ryan. 2000. Pulmonary Immunotoxicology. Pulmonary Immunotoxicology 301 336 .
Lung Chi Chen & Qingshan Qu. (1997) Formation of Intracellular Free Radicals in Guinea Pig Airway Epithelium duringin VitroExposure to Ozone. Toxicology and Applied Pharmacology 143:1, pages 96-101.
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Mitchell D. Cohen, Judith T. Zelikoff, Qingshan Qu & Richard B. Schlesinger. (1996) Effects of ozone upon macrophage-interferon interactions. Toxicology 114:3, pages 243-252.
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Roger McClellan & Rogene Henderson. 1995. Concepts In Inhalation Toxicology. Concepts In Inhalation Toxicology 581 640 .
R.A. Hempenius, I.M.C.M. Rietjens, H.N.A. Grooten & J. de Vries. (1992) Comparative study on the toxicity of methyl linoleate-9, 10-ozonide and cumene hydroperoxide to alveolar macrophages. Toxicology 73:1, pages 23-34.
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Melanie A. Banks, Dale W. Porter, William G. Martin & Vincent Castranova. 1992. Taurine. Taurine 341 354 .
Susanne Becker, Michael C. Madden, Simon L. Newman, Robert B. Devlin & Hillel S. Koren. (1991) Modulation of human alveolar macrophage properties by ozone exposure in vitro. Toxicology and Applied Pharmacology 110:3, pages 403-415.
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D. Scott Cohen, Elise Palmer, William J. Welch & Dean Sheppard. (1991) The Response of Guinea Pig Airway Epithelial Cells and Alveolar Macrophages to Environmental Stress. American Journal of Respiratory Cell and Molecular Biology 5:2, pages 133-143.
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Melanie A. Banks, Dale W. Porter, William G. Martin & Vincent Castranova. (1990) Effects of in vitro ozone exposure on peroxidative damage, membrane leakage, and taurine content of rat alveolar macrophages. Toxicology and Applied Pharmacology 105:1, pages 55-65.
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Elaine S. Wright, Daniel Dziedzic & Candace S. Wheeler. (1990) Cellular, biochemical and functional effects of ozone: new research and perspectives on ozone health effects. Toxicology Letters 51:2, pages 125-145.
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Kevin E. Driscoll & Richard B. Schlesinger. (1988) Alveolar macrophage-stimulated neutrophil and monocyte migration: Effects of in vitro ozone exposure. Toxicology and Applied Pharmacology 93:2, pages 312-318.
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George D. Leikauf, Kevin E. Driscoll & Howard E. Wey. (1988) Ozone-induced Augmentation of Eicosanoid Metabolism in Epithelial Cells from Bovine Trachea. American Review of Respiratory Disease 137:2, pages 435-442.
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