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Journal of Toxicology and Environmental Health Volume 16, 1985 - Issue 5: Ronald Everett Talcott Symposium
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Original Articles

Use of quinones in brain‐tumor therapy: Preliminary results of preclinical laboratory investigations

Mitchel S. Berger Department of Neurological Surgery, University of California, San Francisco, California, 94143
,
Ronald E. Talcott Brain Tumor Research Center, Department of Neurological Surgery, University of California, San Francisco, California
,
Mark L. Rosenblum Brain Tumor Research Center, Department of Neurological Surgery, University of California, San Francisco, California
,
Marilyn Silva Department of Biomedical and Environmental Health Sciences, School of Public Health, University of California, Berkeley, California
,
Francis AliOsman Brain Tumor Research Center, Department of Neurological Surgery, University of California, San Francisco, California
&
Martyn T. Smith Brain Tumor Research Center, Department of Neurological Surgery, University of California, San Francisco, California; Department of Biomedical and Environmental Health Sciences, School of Public Health, University of California, Berkeley, California
Pages 713-719 | Published online: 20 Oct 2009

Citations (22)

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MartynT. Smith. (1985) Quinones as mutagens, carcinogens, and anticancer agents: Introduction and overview. Journal of Toxicology and Environmental Health 16:5, pages 665-672.
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Articles from other publishers (21)

M. F. G. Boriollo, T. A. Silva, M. F. Rodrigues-Netto, J. J. Silva, M. B. Marques, C. T. S. Dias, J. F. Höfling, M. C. C. Resck & N. M. S. Oliveira. (2017) Reduction of doxorubicin-induced genotoxicity by Handroanthus impetiginosus in mouse bone marrow revealed by micronucleus assay. Brazilian Journal of Biology 78:1, pages 1-12.
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Ravi Joshi. (2016) Free Radical Scavenging Reactions of Tetrahydroxyquinone: A Pulse Radiolysis Study. ChemistrySelect 1:5, pages 1084-1091.
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Hsiu-Ni Kung, Tsai-Yun Weng, Yu-Lin Liu, Kuo-Shyan Lu & Yat-Pang Chau. (2014) Sulindac Compounds Facilitate the Cytotoxicity of β-Lapachone by Up-Regulation of NAD(P)H Quinone Oxidoreductase in Human Lung Cancer Cells. PLoS ONE 9:2, pages e88122.
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S Danson, T.H Ward, J Butler & M Ranson. (2004) DT-diaphorase: a target for new anticancer drugs. Cancer Treatment Reviews 30:5, pages 437-449.
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Richard J Knox & Shiuan Chen. 2004. Quinones and Quinone Enzymes, Part B. Quinones and Quinone Enzymes, Part B 194 221 .
Patricia M Flatt, Kornelia Polyak, Luo Jia Tang, Caroline D Scatena, Matthew D Westfall, Laura A Rubinstein, Jian Yu, Kenneth W Kinzler, Bert Vogelstein, Dave E Hill & Jennifer A Pietenpol. (2000) p53-dependent expression of PIG3 during proliferation, genotoxic stress, and reversible growth arrest. Cancer Letters 156:1, pages 63-72.
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J K Kepa & D Ross. (1999) DT-diaphorase activity in NSCLC and SCLC cell lines: a role for fos/jun regulation. British Journal of Cancer 79:11-12, pages 1679-1684.
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Howard D. Beall, Yafei Liu, David Siegel, Emiko M. Bolton, Neil W. Gibson & David Ross. (1996) Role of NAD(P)H:Quinone oxidoreductase (DT-diaphorase) in cytotoxicity and induction of DNA damage by streptonigrin. Biochemical Pharmacology 51:5, pages 645-652.
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G.J. Hammons, G.J. Warren, E. Blann, J. Nichols & B.D. Lyn-Cook. (1995) Increased DT-diaphorase activity in transformed and tumorigenic pancreatic acinar cells. Cancer Letters 96:1, pages 9-14.
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Geoffrey R. Fisher, Laurence H. Patterson & Peter L. Gutierrez. (1993) A comparison of free radical formation by quinone anti-tumour agents in MCF-7 cells and the role of NAD(P)H (quinone-acceptor) oxidoreductase (DT-diaphorase). Chemico-Biological Interactions 88:2-3, pages 137-153.
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Richard J. Knox, Frank Friedlos & Marion P. Boland. (1993) The bioactivation of CB 1954 and its use as a prodrug in antibody-directed enzyme prodrug therapy (ADEPT). Cancer and Metastasis Reviews 12:2, pages 195-212.
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David Ross, David Siegel, Howard Beall, A. S. Prakash, R. Timothy Mulcahy & Neil W. Gibson. (1993) DT-diaphorase in activation and detoxification of quinones. Cancer and Metastasis Reviews 12:2, pages 83-101.
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Robert J. Riley & Paul Workman. (1992) DT-diaphorase and cancer chemotherapy. Biochemical Pharmacology 43:8, pages 1657-1669.
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Robert J. Riley & Paul Workman. (1992) Enzymology of the reduction of the potent benzotriazine-di-n-oxide hypoxic cell cytotoxin SR 4233 (win 59075) by NAD(P)H: (Quinone acceptor) oxidoreductase (EC 1.6.99.2) purified from walker 256 rat tumour cells. Biochemical Pharmacology 43:2, pages 167-174.
Crossref
Marion P. Boland, Richard J. Knox & John J. Roberts. (1991) The differences in kinetics of rat and human DT diaphorase result in a differential sensitivity of derived cell lines to CB 1954 (5-(aziridin-1-yl)-2,4-dinitrobenzamide). Biochemical Pharmacology 41:6-7, pages 867-875.
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John J. Schlager & Garth Powis. (1990) Cytosolic NAD(P)H:(Quinone-acceptor)oxidoreductase in human normal and tumor tissue: Effects of cigarette smoking and alcohol. International Journal of Cancer 45:3, pages 403-409.
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Christina Lind, Enrique Cadenas, Paul Hochstein & Lars Ernster. 1990. Oxygen Radicals in Biological Systems Part B: Oxygen Radicals and Antioxidants. Oxygen Radicals in Biological Systems Part B: Oxygen Radicals and Antioxidants 287 301 .
Garth Powis. (1989) Free radical formation by antitumor quinones. Free Radical Biology and Medicine 6:1, pages 63-101.
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Peter Kovacic, James R. Ames, James W. Grogan, Banasri Hazra & Michael D. Ryan. 1989. Redox Chemistry and Interfacial Behavior of Biological Molecules. Redox Chemistry and Interfacial Behavior of Biological Molecules 295 307 .
Garth Powis, Kevin Lee See, Kenneth S. Santone, Deborah C. Melder & Ernest M. Hodnett. (1987) Quinoneimines as substrates for quinone reductase (NAD(P)H : (Quinone-acceptor)oxidoreductase) and the effect of dicumarol on their cytotoxicity. Biochemical Pharmacology 36:15, pages 2473-2479.
Crossref
Garth Powis. (1987) Metabolism and reactions of quinoid anticancer agents. Pharmacology & Therapeutics 35:1-2, pages 57-162.
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