21
Views
38
CrossRef citations to date
0
Altmetric
Original Articles

Toxicity of ozone and nitrogen dioxide to alveolar macrophages: Comparative study revealing differences in their mechanism of toxic action

, , , &
Pages 555-568 | Received 07 Apr 1986, Accepted 19 Jun 1986, Published online: 20 Oct 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (13)

Raymond F. Hamilton Jr, Andrij Holian. (2000) PROTECTION AGAINST OZONE-INDUCED PULMONARY INFLAMMATION AND CELL DEATH BY ENDOTOXIN PRETREATMENT IN MICE: ROLE OF HO-1. Inhalation Toxicology 12:12, pages 1225-1238.
Read now
Carl J. Johnston, Christina K. Reed, Nelly E. Avissar, Robert Gelein, Jacob N. Finkelstein. (2000) ANTIOXIDANT AND INFLAMMATORY RESPONSE AFTER ACUTE NITROGEN DIOXIDE AND OZONE EXPOSURES IN C57Bl/6 MICE. Inhalation Toxicology 12:3, pages 187-203.
Read now
Sonia Tabacova, Donna Day Baird & Liudmila Balabaeva. (1998) Exposure to Oxidized Nitrogen: Lipid Peroxidation and Neonatal Health Risk. Archives of Environmental Health: An International Journal 53:3, pages 214-221.
Read now
Nadine Bernard, Monique Saintot, Cecile Astre & Mariette Gerber. (1998) Personal Exposure to Nitrogen Dioxide Pollution and Effect on Plasma Antioxidants. Archives of Environmental Health: An International Journal 53:2, pages 122-128.
Read now
Steven R. Kleeberger, Liu-Yi Zhang & George J. Jakab. (1997) DIFFERENTIAL SUSCEPTIBILITY TO OXIDANT EXPOSURE IN INBRED STRAINS OF MICE: NITROGEN DIOXIDE VERSUS OZONE. Inhalation Toxicology 9:7, pages 601-621.
Read now
Richard B. Schlesinger, Hassan A. N. El-fawal, Judith T. Zelikoff, John E. Gorczynski, Timothy Mcgovern, Christine E. Nadziejko & Lung Chi Chen. (1994) Pulmonary Effects of Repeated Episodic Exposures to Nitric Acid Vapor Alone and in Combination with Ozone. Inhalation Toxicology 6:1, pages 21-41.
Read now
Gerhard Polzer, Ines Lind, Evelyn Krüger & Arnulf Seidel. (1994) In Vitro Effects of Nitrogen Dioxide on the Release of Superoxide Anions, Tnf-α, and IL-8 by HL60-Macrophages and Bovine Alveolar Macrophages. Inhalation Toxicology 6:4, pages 359-377.
Read now
Richard B. Schlesinger, Patricia A. Weideman & Judith T. Zelikoff. (1991) Effects of Repeated Exposures to Ozone and Nitrogen Dioxide on Respiratory Tract Prostanoids. Inhalation Toxicology 3:1, pages 27-36.
Read now
RichardB. Schlesinger, KevinE. Driscoll, AlbertF. Gunnison & JudithT. Zelikoff. (1990) Pulmonary arachidonic acid metabolism following acute exposures to ozone and nitrogen dioxide. Journal of Toxicology and Environmental Health 31:4, pages 275-290.
Read now
I. M. C. M. Rietjens, C. A. M. van Tilburg, T. M. M. Coenen, G. M. Alink & A. W. T. Konings. (1987) Influence of polyunsaturated fatty acid supplementation and membrane fluidity on ozone and nitrogen dioxide sensitivity of rat alveolar macrophages. Journal of Toxicology and Environmental Health 21:1-2, pages 45-56.
Read now

Articles from other publishers (25)

Renchao Chen, Jun Yang, Chunlin Zhang, Bixia Li, Stéphanie Bergmann, Fangfang Zeng, Hao Wang & Boguang Wang. (2019) Global Associations of Air Pollution and Conjunctivitis Diseases: A Systematic Review and Meta-Analysis. International Journal of Environmental Research and Public Health 16:19, pages 3652.
Crossref
Mateus G. Masteghin, Denis R. M. Godoi & Marcelo O. Orlandi. (2019) Heating Method Effect on SnO Micro-Disks as NO2 Gas Sensor. Frontiers in Materials 6.
Crossref
Borut Poljšak & Rok Fink. (2014) The Protective Role of Antioxidants in the Defence against ROS/RNS-Mediated Environmental Pollution. Oxidative Medicine and Cellular Longevity 2014, pages 1-22.
Crossref
Daniel B. Menzel & Dianne M. Meacher. 2002. Reactive Oxygen Species in Biological Systems. Reactive Oxygen Species in Biological Systems 335 366 .
J Cotovio, L Onno, P Justine, S Lamure & P Catroux. (2001) Generation of oxidative stress in human cutaneous models following in vitro ozone exposure. Toxicology in Vitro 15:4-5, pages 357-362.
Crossref
Mitchell D. Cohen, Maureen Sisco, Yun Li, Judith T. Zelikoff & Richard B. Schlesinger. (2001) Ozone-Induced Modulation of Cell-Mediated Immune Responses in the Lungs. Toxicology and Applied Pharmacology 171:2, pages 71-84.
Crossref
A. M. Sciuto & T. S. Moran. (2001) Effect of dietary treatment with n ‐propyl gallate or vitamin E on the survival of mice exposed to phosgene . Journal of Applied Toxicology 21:1, pages 33-39.
Crossref
L van Bree, I MCM Rietjens, G M Alink, J AMA Dormans, M Marra & P JA Rombout. (2016) Biochemical and morphological changes in lung tissue and isolated lung cells of rats induced by short-term nitrogen dioxide exposure. Human & Experimental Toxicology 19:7, pages 392-401.
Crossref
M. A. Spiteri, A. Bianco, R. C. Strange & A. A. Fryer. (2000) Polymorphisms at the glutathione S-transferase, GSTP1 locus: a novel mechanism for susceptibility and development of atopic airway inflammation. Allergy 55:suppl 61, pages 15-20.
Crossref
Lisa K. Ryan. 2000. Pulmonary Immunotoxicology. Pulmonary Immunotoxicology 301 336 .
Milan J. Hazucha. 1999. Air Pollution and Health. Air Pollution and Health 511 529 .
Elliott Berlin, Melanie A. Banks, Sam J. Bhathena, Renee C. Peters & Wesley A. Johnson. 1996. Advances in Swine in Biomedical Research. Advances in Swine in Biomedical Research 581 593 .
Ba Tu, Alf Wallin, Peter Moldeus & Ian A. Cotgreave. (1995) Cytotoxicity of NO2 gas to cultured human and murine cells in an inverted monolayer exposure system. Toxicology 96:1, pages 7-18.
Crossref
Gad A. Simon, Peter Schmid, William G. Reifenrath, Theodore van Ravenswaay & Bruce E. Stuck. (1994) Wound Healing after Laser Injury to Skin—The Effect of Occlusion and Vitamin E †. Journal of Pharmaceutical Sciences 83:8, pages 1101-1106.
Crossref
Ellen M. Drost, Colin Selby, Myrtle M. E. Bridgeman & William Macnee. (1993) Decreased Leukocyte Deformability after Acute Cigarette Smoking in Humans. American Review of Respiratory Disease 148:5, pages 1277-1283.
Crossref
R.A. Hempenius, I.M.C.M. Rietjens, H.N.A. Grooten & J. de Vries. (1992) Comparative study on the toxicity of methyl linoleate-9, 10-ozonide and cumene hydroperoxide to alveolar macrophages. Toxicology 73:1, pages 23-34.
Crossref
Melanie A. Banks, Dale W. Porter, William G. Martin & Vincent Castranova. (1991) Ozone-induced lipid peroxidation and membrane leakage in isolated rat alveolar macrophages: protective effects of taurine. The Journal of Nutritional Biochemistry 2:6, pages 308-313.
Crossref
Melanie A. Banks, Dale W. Porter, William G. Martin & Vincent Castranova. (1990) Effects of in vitro ozone exposure on peroxidative damage, membrane leakage, and taurine content of rat alveolar macrophages. Toxicology and Applied Pharmacology 105:1, pages 55-65.
Crossref
Elaine S. Wright, Daniel Dziedzic & Candace S. Wheeler. (1990) Cellular, biochemical and functional effects of ozone: new research and perspectives on ozone health effects. Toxicology Letters 51:2, pages 125-145.
Crossref
Mark W. Frampton, Jacob N. Finkelstein, Norbert J. RobertsJr.Jr., Anthony M. Smeglin, Paul E. Morrow & Mark J. Utell. (1989) Effects of Nitrogen Dioxide Exposure on Bronchoalveolar Lavage Proteins in Humans. American Journal of Respiratory Cell and Molecular Biology 1:6, pages 499-505.
Crossref
I. Rietjens, L. Van Bree, A. Konings, P. Rombout & G. Alink. 1989. 513 522 .
Ling-Yi Chang, Robert R. Mercer, Barbara L. Stockstill, Frederick J. Miller, Judith A. Graham, Jean J. Ospital & James D. Crapo. (1988) Effects of low levels of NO2 on terminal bronchiolar cells and its relative toxicity compared to O3. Toxicology and Applied Pharmacology 96:3, pages 451-464.
Crossref
Catherine Whiteside & Hosni M. Hassan. (1988) Role of oxyradicals in the inactivation of catalase by ozone. Free Radical Biology and Medicine 5:5-6, pages 305-312.
Crossref
G. M. Alink & I. M. C. M. Rietjens. 1988. Environmental Hygiene. Environmental Hygiene 7 10 .
I.M.C.M. Rietjens, H.H. Lemmink, G.M. Alink & P.J. Van Bladeren. (1987) The role of glutathione and glutathione S-transferases in fatty acid ozonide detoxification. Chemico-Biological Interactions 62:1, pages 3-14.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.