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Journal of Toxicology and Environmental Health Volume 24, 1988 - Issue 4
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Original Articles

Qualitative and quantitative changes in cytochrome p‐450‐dependent xenobiotic metabolism in pulmonary microsomes and isolated clara cell populations derived from ozone‐exposed rats

I. M. C. M. Rietjens Department of Biochemistry, Agricultural University, De Dreyen 11, Wageningen, 6703 BC, The Netherlands; Laboratory of Toxicology, National Institute of Public Health and Environmental Protection, Bilthoven, The Netherlands
,
J. A. M. A. Dormans Laboratory of Pathology, National Institute of Public Health and Environmental Protection, Bilthoven, The Netherlands
,
P. J. A. Rombout Laboratory of Toxicology, National Institute of Public Health and Environmental Protection, Bilthoven, The Netherlands
&
L. van Bree Laboratory of Toxicology, National Institute of Public Health and Environmental Protection, P.O. Box 1, Bilthoven, 3720 BA, The Netherlands
Pages 515-531 | Received 25 Aug 1987, Accepted 08 Dec 1987, Published online: 19 Oct 2009

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Jerry Campbell, Allison Franzen, Cynthia Van Landingham, Michael Lumpkin, Susan Crowell, Clive Meredith, Anne Loccisano, Robinan Gentry & Harvey Clewell. (2016) Predicting lung dosimetry of inhaled particleborne benzo[a]pyrene using physiologically based pharmacokinetic modeling. Inhalation Toxicology 28:11, pages 520-535.
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Jerry L. Campbell, Melvin E. Andersen & Harvey J. Clewell. (2014) A hybrid CFD-PBPK model for naphthalene in rat and human with IVIVE for nasal tissue metabolism and cross-species dosimetry. Inhalation Toxicology 26:6, pages 333-344.
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A. Delaunois, S. Florquin, P. Segura, LM Montano, MH Vargas & P. Gustin. (1999) INTERACTIONS BETWEEN CYTOCHROME P-450 ACTIVITIES AND OZONE-INDUCED MODULATORY EFFECTS ON ENDOTHELIAL PERMEABILITY IN RABBIT LUNGS: Influence of Gender. Inhalation Toxicology 11:11, pages 999-1014.
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Ram K. Sindhu, William J. Mautz, Ichiro Fujita, Nai-San Wang & Yutaka Kikkawa. (1996) Effect of Chronic Exposure to Ozone and Nitric Acid on Cytochrome P-450 Monooxygenase System of Rat Lung and Liver. Inhalation Toxicology 8:7, pages 695-708.
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Leendert van Bree, Paul G. J. Reuzel, Marian A. Verhoef, Jan Bos & Peter J. A. Rombout. (1990) Effects of Acute Inhalation of Respirable Coal Fly Ash on Metabolic Defense Capability of the Rat Lung. Inhalation Toxicology 2:4, pages 361-373.
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H. W. Balfoort, H. J. Th. Bloemen, L. van Bree, J. A. M. A. Dormans & P. J. A. Rombout. (1989) Tolerance to Ozone Induced in Rats by Preexposure to Cadmium Chloride Aerosol. Inhalation Toxicology 1:2, pages 139-152.
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Articles from other publishers (17)

Mark Johnson, Shayne Gad & Christopher Kemper. 2015. Animal Models in Toxicology, Third Edition. Animal Models in Toxicology, Third Edition 153 283 .
Paul A. White, George R. Douglas, John Gingerich, Craig Parfett, Phil Shwed, Vern Seligy, Lynda Soper, Lynn Berndt, Janet Bayley, Shelley Wagner, Kathleen Pound & David Blakey. (2003) Development and characterization of a stable epithelial cell line from Muta™Mouse lung. Environmental and Molecular Mutagenesis 42:3, pages 166-184.
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Renee C. Paige & Charles G. Plopper. 1999. Air Pollution and Health. Air Pollution and Health 531 557 .
Ram K. Sindhu, Ronald E. Rasmussen & Yutaka Kikkawa. 1999. Tryptophan, Serotonin, and Melatonin. Tryptophan, Serotonin, and Melatonin 409 418 .
Katherine C. Watt, Charles G. Plopper, Alison J. Weir, Brian Tarkington & Alan R. Buckpitt. (1998) Cytochrome P450 2E1 in Rat Tracheobronchial Airways: Response to Ozone Exposure. Toxicology and Applied Pharmacology 149:2, pages 195-202.
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Lisa M. Sweeney, Michael L. Shuler, Deborah J. Quick & John G. Babish. (1996) A preliminary physiologically based pharmacokinetic model for naphthalene and naphthalene oxide in mice and rats. Annals of Biomedical Engineering 24:2, pages 305-320.
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UNA S. RYAN & ALBERT P. LI. 1993. Metabolic Activation and Toxicity of Chemical Agents to Lung Tissue and Cells. Metabolic Activation and Toxicity of Chemical Agents to Lung Tissue and Cells 107 122 .
THEODORA R. DEVEREUX, BARBARA A. DOMIN & RICHARD M. PHILPOT. 1993. Metabolic Activation and Toxicity of Chemical Agents to Lung Tissue and Cells. Metabolic Activation and Toxicity of Chemical Agents to Lung Tissue and Cells 25 40 .
Walter G. Balvers, Marelle G. Boersma, Cees Veeger & Ivonne M.C.M. Rietjens. (1992) Differential cumene hydroperoxide sensitivity of cytochrome P-450 enzymes IA1 and IIB1 determined by their way of membrane incorporation. Biochimica et Biophysica Acta (BBA) - General Subjects 1117:2, pages 179-187.
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Steven A. Lacy, James B. Mangum & Jeffrey I. Everitt. (1992) Cytochrome P-450- and glutathione-associated enzyme activities in freshly isolated enriched lung cell fractions from β-naphthoflavone-treated male F344 rats. Toxicology 73:2, pages 147-160.
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Etsu Suzuki, Yuji Takahashi, Shinsuke Aida, Yuji Kimula, Yuzo Ito & Takashi Miura. (1992) Alteration in surface structure of Clara cells and pulmonary cytochrome P-450b level in rats exposed to ozone. Toxicology 71:3, pages 223-232.
Crossref
S. R. Kleeberger, M. A. Trush & L. Y. Zhang. 1992. Environmental Hygiene III. Environmental Hygiene III 113 116 .
Deborah Dillon, Robert Combes, Malcolm McConville & Errol Zeiger. (2006) Ozone is mutagenic in salmonella. Environmental and Molecular Mutagenesis 19:4, pages 331-337.
Crossref
Takahashi Yuji & Miura Takashi. (1990) Responses of cytochrome P-450 isozymes of rat lung to in vivo exposure to ozone. Toxicology Letters 54:2-3, pages 327-335.
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Leendert Van Bree, Paul J. Lioy, Peter J.A. Rombout & Morton Lippmann. (1990) A more stringent and longer-term standard for tropospheric ozone. Toxicology and Applied Pharmacology 103:3, pages 377-382.
Crossref
J. A. M. A. Dormans. (1989) Application of the disector method in the light microscopic quantification of type II pneumocytes in control and ozone-exposed rats. Journal of Microscopy 155:2, pages 207-211.
Crossref
L. Van Bree, P.J.A Rombout, I.M.C.M. Rietjens, J.A.M.A. Dormans & M. Marra. 1989. 723 732 .

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