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Session II. Novel biomarkers of toxicant exposure

Rationale for selecting exfoliated bladder cell micronuclei as potential biomarkers for arsenic genotoxicity

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Pages 223-234 | Published online: 19 Oct 2009

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Aihua Zhang, Huiyao Li, Yun Xiao, Liping Chen, Xiaonian Zhu, Jun Li, Lu Ma, Xueli Pan, Wen Chen & Zhini He. (2017) Aberrant methylation of nucleotide excision repair genes is associated with chronic arsenic poisoning. Biomarkers 22:5, pages 429-438.
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Samuel M. Cohen, Lora L. Arnold, Barbara D. Beck, Ari S. Lewis & Michal Eldan. (2013) Evaluation of the carcinogenicity of inorganic arsenic. Critical Reviews in Toxicology 43:9, pages 711-752.
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Defa Tian, Hengzhi MA, Zumei Feng, Yajuan Xia, X. Chris Le, Zhishang Ni, James Allen, Barbara Collins, Dina Schreinemachers & Judy L. Mumford. (2001) ANALYSES OF MICRONUCLEI IN EXFOLIATED EPITHELIAL CELLS FROM INDIVIDUALS CHRONICALLY EXPOSED TO ARSENIC VIA DRINKING WATER IN INNER MONGOLIA, CHINA. Journal of Toxicology and Environmental Health, Part A 64:6, pages 473-484.
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Articles from other publishers (24)

Nilanjana Roy Chowdhury, Madhurima Joardar, Antara Das, Deepanjan Mridha, Sharmistha Majumder, Monojit Mondal, Nilanjana Banerjee & Tarit Roychowdhury. (2023) Appraisal of acute and chronic arsenic exposure in differently exposed school children with special reference to micronuclei formation in urine epithelial cells: A comparative study in West Bengal, India. Groundwater for Sustainable Development 21, pages 100917.
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Stefano Bonassi & Michael Fenech. 2019. The Micronucleus Assay in Toxicology. The Micronucleus Assay in Toxicology 38 78 .
Arjeta Podrimaj-Bytyqi, Ana Borovečki, Qerim Selimi, Suzana Manxhuka-Kerliu, Goneta Gashi & Isa R. Elezaj. (2018) The frequencies of micronuclei, nucleoplasmic bridges and nuclear buds as biomarkers of genomic instability in patients with urothelial cell carcinoma. Scientific Reports 8:1.
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Jinia Sinha Roy, Debmita Chatterjee, Nandana Das & Ashok K. Giri. (2018) Substantial Evidences Indicate That Inorganic Arsenic Is a Genotoxic Carcinogen: a Review. Toxicological Research 34:4, pages 311-324.
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Prasenjit Roy, Anita Mukherjee & Sarbani Giri. (2016) Evaluation of genetic damage in tobacco and arsenic exposed population of Southern Assam, India using buccal cytome assay and comet assay. Ecotoxicology and Environmental Safety 124, pages 169-176.
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Victor Hugo Pereira da Silva, Carolina Foot Gomes de Moura, Flavia Andressa Pidone Ribeiro, Augusto Cesar, Camilo Dias Seabra Pereira, Marcelo Jose Dias Silva, Wagner Vilegas & Daniel Araki Ribeiro. (2014) Genotoxicity and cytotoxicity induced by municipal effluent in multiple organs of Wistar rats. Environmental Science and Pollution Research 21:22, pages 13069-13080.
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Afifa Kausar, Sarbani Giri, Prasenjit Roy & Anirudha Giri. (2014) Changes in buccal micronucleus cytome parameters associated with smokeless tobacco and pesticide exposure among female tea garden workers of Assam, India. International Journal of Hygiene and Environmental Health 217:2-3, pages 169-175.
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Somnath Paul, Nilanjana Banerjee, Aditi Chatterjee, Tanmoy J. Sau, Jayanta K. Das, Prafulla K. Mishra, Partha Chakrabarti, Arun Bandyopadhyay & Ashok K. Giri. (2014) Arsenic-induced promoter hypomethylation and over-expression of ERCC2 reduces DNA repair capacity in humans by non-disjunction of the ERCC2–Cdk7 complex. Metallomics 6:4, pages 864.
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Somnath Paul, Pritha Bhattacharjee, Prafulla K. Mishra, Debmita Chatterjee, Anirban Biswas, Debasree Deb, Aloke Ghosh, D. N. Guha Mazumder & Ashok K. Giri. (2013) Human urothelial micronucleus assay to assess genotoxic recovery by reduction of arsenic in drinking water: a cohort study in West Bengal, India. BioMetals 26:5, pages 855-862.
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Susana Alicia Bartolotta, Matias Gabriel Pacskowski, Adriana Hick & Marta Ana Carballo. (2010) Micronuclei Assay in Exfoliated Buccal Cells from Individuals Exposed to Arsenic in Argentina. Archives of Environmental Contamination and Toxicology 61:2, pages 337-343.
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Yun Huang, Heli Hou, Qiyi Yi, Yingyin Zhang, Dawei Chen, Erkang Jiang, Yunfei Xia, Michael Fenech & Qinghua Shi. (2011) The fate of micronucleated cells post X-irradiation detected by live cell imaging. DNA Repair 10:6, pages 629-638.
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Xuefeng Ren, Cliona M. McHale, Christine F. Skibola, Allan H. Smith, Martyn T. Smith & Luoping Zhang. (2011) An Emerging Role for Epigenetic Dysregulation in Arsenic Toxicity and Carcinogenesis. Environmental Health Perspectives 119:1, pages 11-19.
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Marc Bartel, Franziska Ebert, Larissa Leffers, Uwe Karst & Tanja Schwerdtle. (2011) Toxicological Characterization of the Inorganic and Organic Arsenic Metabolite Thio- in Cultured Human Lung Cells . Journal of Toxicology 2011, pages 1-9.
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. (2009) Scientific Opinion on Arsenic in Food. EFSA Journal 7:10, pages 1351.
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Pritha Ghosh, Arindam Basu, Keshav K Singh & Ashok K Giri. (2008) Evaluation of cell types for assessment of cytogenetic damage in arsenic exposed population. Molecular Cancer 7:1.
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J.R. Meliker & J.O. Nriagu. 2007. Arsenic in Soil and Groundwater Environment - Biogeochemical Interactions, Health Effects and Remediation. Arsenic in Soil and Groundwater Environment - Biogeochemical Interactions, Health Effects and Remediation 551 584 .
V. Martínez, A. Creus, W. Venegas, A. Arroyo, J.P. Beck, T.W. Gebel, J. Surrallés & R. Marcos. (2005) Micronuclei assessment in buccal cells of people environmentally exposed to arsenic in northern Chile. Toxicology Letters 155:2, pages 319-327.
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Anamika Basu, Pritha Ghosh, Jayanta K. Das, Apurba Banerjee, Kunal Ray & Ashok K. Giri. (2004) Micronuclei as Biomarkers of Carcinogen Exposure in Populations Exposed to Arsenic Through Drinking Water in West Bengal, India: A Comparative Study in Three Cell Types. Cancer Epidemiology, Biomarkers & Prevention 13:5, pages 820-827.
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Geetha Ranmuthugala, Louis Pilotto, Wayne Smith, Titus Vimalasiri, Keith Dear & Robert Douglas. (2003) Chlorinated Drinking Water and Micronuclei in Urinary Bladder Epithelial Cells. Epidemiology 14:5, pages 617-622.
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A. Basu, J. Mahata, A.K. Roy, J.N. Sarkar, G. Poddar, A.K. Nandy, P.K. Sarkar, P.K. Dutta, A. Banerjee, M. Das, K. Ray, S. Roychaudhury, A.T. Natarajan, R. Nilsson & A.K. Giri. (2002) Enhanced frequency of micronuclei in individuals exposed to arsenic through drinking water in West Bengal, India. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 516:1-2, pages 29-40.
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A H Smith, A P Arroyo, D N Mazumder, M J Kosnett, A L Hernandez, M Beeris, M M Smith & L E Moore. (2000) Arsenic-induced skin lesions among Atacameño people in Northern Chile despite good nutrition and centuries of exposure.. Environmental Health Perspectives 108:7, pages 617-620.
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G. Reifferscheid & T. Grummt. 2000. Environmental Challenges. Environmental Challenges 67 79 .
Mary Lou Biggs, David A. Kalman, Lee E. Moore, Claudia Hopenhayn-Rich, Martyn T. Smith & Allan H. Smith. (1997) Relationship of urinary arsenic to intake estimates and a biomarker of effect, bladder cell micronuclei. Mutation Research/Reviews in Mutation Research 386:3, pages 185-195.
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M.P. Lehucher-Michel, Y.Ait Amara-Mokrane, B. Devictor, P. Catilina & A. Botta. (1996) Micronuclei kinetics of exfoliated urothelial cells. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 354:1, pages 1-7.
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