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Research Article

Studying the Effects of Lead on DNA Fragmentation and Proapoptotic Bax and Antiapoptotic Bcl-2 Protein Expression in PC12 Cells

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Pages 75-79 | Received 24 Nov 2006, Accepted 26 Jan 2007, Published online: 09 Oct 2008

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Read on this site (3)

Ali M. Sharifi, Roshanak Ghazanfari, Neda Tekiyehmaroof & Mohammad A. Sharifi. (2011) Investigating the effect of lead acetate on rat bone marrow-derived mesenchymal stem cells toxicity: Role of apoptosis. Toxicology Mechanisms and Methods 21:3, pages 225-230.
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Ali M. Sharifi, Fotovat Eskandari Hoda & Amir Mozaffari Noor. (2010) Studying the effect of LPS on cytotoxicity and apoptosis in PC12 neuronal cells: Role of Bax, Bcl-2, and Caspase-3 protein expression. Toxicology Mechanisms and Methods 20:6, pages 316-320.
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Articles from other publishers (17)

Juwon Choi, Yoo Sung Kim, Mi-Hye Kim, Hee Jung Kim & Bo-Eun Yoon. (2022) Maternal lead exposure induces sex-dependent cerebellar glial alterations and repetitive behaviors. Frontiers in Cellular Neuroscience 16.
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Magdalini Sachana, John Flaskos & Alan J. Hargreaves. 2022. Reproductive and Developmental Toxicology. Reproductive and Developmental Toxicology 179 209 .
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Xiaopeng Wang & Jing Zhao. (2019) Neuroprotective effect of CPCGI on Alzheimer's disease and its mechanism. Molecular Medicine Reports.
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Nur Fatin Nabilah Mohd Sahardi & Suzana Makpol. (2019) Ginger ( Zingiber officinale Roscoe) in the Prevention of Ageing and Degenerative Diseases: Review of Current Evidence . Evidence-Based Complementary and Alternative Medicine 2019, pages 1-13.
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Jiawen Peng, Fan Zhou, Yuhao Wang, Yongjie Xu, Hongnan Zhang, Fei Zou & Xiaojing Meng. (2019) Differential response to lead toxicity in rat primary microglia and astrocytes. Toxicology and Applied Pharmacology 363, pages 64-71.
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Hanaa Mahmoud Ali. (2018) Mitigative role of garlic and vitamin E against cytotoxic, genotoxic, and apoptotic effects of lead acetate and mercury chloride on WI-38 cells. Pharmacological Reports 70:4, pages 804-811.
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Magdalini Sachana, John Flaskos & Alan J. Hargreaves. 2017. Reproductive and Developmental Toxicology. Reproductive and Developmental Toxicology 255 288 .
Fang Ye, Xiaoyi Li, Lili Li, Jing Yuan & Jun Chen. (2016) t-BHQ Provides Protection against Lead Neurotoxicity via Nrf2/HO-1 Pathway. Oxidative Medicine and Cellular Longevity 2016, pages 1-15.
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Talia Sanders, Yi-Ming Liu & Paul B. Tchounwou. (2015) Cytotoxic, genotoxic, and neurotoxic effects of Mg, Pb, and Fe on pheochromocytoma (PC-12) cells. Environmental Toxicology 30:12, pages 1445-1458.
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Chengchong Li, Zhi Pan, Tianjiao Xu, Chun Zhang, Qi Wu & Yingcai Niu. (2014) Puerarin induces the upregulation of glutathione levels and nuclear translocation of Nrf2 through PI3K/Akt/GSK-3β signaling events in PC12 cells exposed to lead. Neurotoxicology and Teratology 46, pages 1-9.
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I. Baranowska-Bosiacka, L. Strużyńska, I. Gutowska, A. Machalińska, A. Kolasa, P. Kłos, G.A. Czapski, M. Kurzawski, A. Prokopowicz, M. Marchlewicz, K. Safranow, B. Machaliński, B. Wiszniewska & D. Chlubek. (2013) Perinatal exposure to lead induces morphological, ultrastructural and molecular alterations in the hippocampus. Toxicology 303, pages 187-200.
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Ahmed E. Abdel Moneim, Mohamed A. Dkhil & Saleh Al-Quraishy. (2011) Effects of Flaxseed Oil on Lead Acetate-Induced Neurotoxicity in Rats. Biological Trace Element Research 144:1-3, pages 904-913.
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Leila Seddik, Thierno Madjou Bah, Abdelkader Aoues, Miloud Slimani & Mohamed Benderdour. (2011) Elucidation of mechanisms underlying the protective effects of olive leaf extract against lead-induced neurotoxicity in Wistar rats. The Journal of Toxicological Sciences 36:6, pages 797-809.
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Magdalini Sachana, John Flaskos & Alan J. Hargreaves. 2011. Reproductive and Developmental Toxicology. Reproductive and Developmental Toxicology 227 252 .
Ali M. Sharifi, Seyed Hadi Mousavi & Masoumeh Jorjani. (2010) Effect of Chronic Lead Exposure on Pro-Apoptotic Bax and Anti-Apoptotic Bcl-2 Protein Expression in Rat Hippocampus In Vivo. Cellular and Molecular Neurobiology 30:5, pages 769-774.
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