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Toxicology Mechanisms and Methods Volume 27, 2017 - Issue 6
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Review Article

Glutathione S-transferase A1 (GSTA1) as a marker of acetaminophen-induced hepatocyte injury in vitro

Rui LiCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, PR China; View further author information
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Fangping LiuCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, PR China; Correspondence[email protected]
View further author information
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Yicong ChangCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, PR China; View further author information
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Xin MaCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, PR China; View further author information
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Minmin LiCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, PR China; View further author information
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Changwen LiHarbin Veterinary Research Institute of Chinese Academy of Agricultural Sciences, Harbin, PR ChinaView further author information
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Chenxi ShiCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, PR China; View further author information
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Jingshan HeCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, PR China; View further author information
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Ying LiCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, PR China; View further author information
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Zhi LiCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, PR China; View further author information
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Yuexia LinCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, PR China; View further author information
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Qing HanCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, PR China; View further author information
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Yulin ZhaoCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, PR China; View further author information
&
Dening WangCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, PR China; View further author information
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Pages 401-407 | Received 04 Nov 2016, Accepted 08 Apr 2017, Published online: 02 May 2017

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Krishnamoorthy Mohana & Anant Achary. (2017) Human cytosolic glutathione-S-transferases: quantitative analysis of expression, comparative analysis of structures and inhibition strategies of isozymes involved in drug resistance. Drug Metabolism Reviews 49:3, pages 318-337.
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Articles from other publishers (12)

Qian Zhou, Qixiu Zhou, Rui Xia, Peng Zhang, Yanqing Xie, Zhuya Yang, Afsar Khan, Zhihong Zhou, Wenhong Tan & Lu Liu. (2023) Swertiamarin or heat-transformed products alleviated APAP-induced hepatotoxicity via modulation of apoptotic and Nrf-2/NF-κB pathways. Heliyon 9:8, pages e18746.
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Kodihalli C. Ravindra, Vishal S. Vaidya, Zhenyu Wang, Joel D. Federspiel, Richard Virgen-Slane, Robert A. Everley, Jane I. Grove, Camilla Stephens, Mireia F. Ocana, Mercedes Robles-Díaz, M. Isabel Lucena, Raul J. Andrade, Edmond Atallah, Alexander L. Gerbes, Sabine Weber, Helena Cortez-Pinto, Andrew J. Fowell, Hyder Hussaini, Einar S. Bjornsson, Janisha Patel, Guido Stirnimann, Sumita Verma, Ahmed M. Elsharkawy, William J. H. Griffiths, Craig Hyde, James W. Dear, Guruprasad P. Aithal & Shashi K. Ramaiah. (2023) Tandem mass tag-based quantitative proteomic profiling identifies candidate serum biomarkers of drug-induced liver injury in humans. Nature Communications 14:1.
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Xinying Du, Xinhai Cui, Xiaowen Sun, Hui Li, Kuo Xu & Xianjun Fu. (2023) Platycodin D-Induced Immunotoxicity in RAW 264.7 Macrophages via Oxidative Stress-Mediated Apoptosis. Natural Product Communications 18:2, pages 1934578X2211503.
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Soju Kimura, Tsukasa Osaki, Takujiro Homma, Sotai Kimura, Sho Kobayashi, Masaki Nakane, Satoshi Miyata, Hiroshi Itoh, Kaneyuki Kawamae & Junichi Fujii. (2022) The concerted elevation of conjugation reactions is associated with the aggravation of acetaminophen toxicity in Akr1a-knockout mice with an ascorbate insufficiency. Life Sciences 304, pages 120694.
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Irina Teslenko, Christy J.W. Watson, Zuping Xia, Gang Chen & Philip Lazarus. (2021) Characterization of Cytosolic Glutathione S -Transferases Involved in the Metabolism of the Aromatase Inhibitor, Exemestane . Drug Metabolism and Disposition 49:12, pages 1047-1055.
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Yuanyuan Zhang, Bingke Ma, Shuangshuang Hao, Jiaqi Wang, Ruichen Zhang, Muhammad Ishfaq, Chenxi Shi, Liang Yuan, Rui Li, Changwen Li & Fangping Liu. (2021) Drug‐induced liver injury: Oltipraz and C2‐ceramide intervene HNF‐1α/GSTA1 expression via JNK signaling pathway. Journal of Applied Toxicology 41:12, pages 2011-2020.
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Yicong Chang, Jingshan He, Bingke Ma, Muhammad Ishfaq, Jiaqi Wang, Ruichen Zhang, Liang Yuan, Jiarui Liu, Changwen Li & Fangping Liu. (2021) Prevention of acetaminophen-induced hepatocyte injury: JNK inhibition and GSTA1 involvement. Molecular & Cellular Toxicology 17:2, pages 161-168.
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Yicong Chang, Feng Wang, Yang Yang, Yuanyuan Zhang, Ishfaq Muhammad, Rui Li, Changwen Li, Ying Li, Chenxi Shi, Xin Ma, Beili Hao & Fangping Liu. (2019) Acetaminophen‐induced hepatocyte injury: C2‐ceramide and oltipraz intervention, hepatocyte nuclear factor 1 and glutathione S ‐transferase A1 changes . Journal of Applied Toxicology 39:12, pages 1640-1650.
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Yuhua Li, Qiang Meng, Mengbi Yang, Dongyang Liu, Xiangyu Hou, Lan Tang, Xin Wang, Yuanfeng Lyu, Xiaoyan Chen, Kexin Liu, Ai-Ming Yu, Zhong Zuo & Huichang Bi. (2019) Current trends in drug metabolism and pharmacokinetics. Acta Pharmaceutica Sinica B 9:6, pages 1113-1144.
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Xin Ma, Yicong Chang, Yuanyuan Zhang, Ishfaq Muhammad, Chenxi Shi, Rui Li, Changwen Li, Zhi Li, Yuexia Lin, Qing Han & Fangping Liu. (2018) Effects of C2-Ceramide and Oltipraz on Hepatocyte Nuclear Factor-1 and Glutathione S-Transferase A1 in Acetaminophen-Mediated Acute Mice Liver Injury. Frontiers in Pharmacology 9.
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Ying Li, Zhi Li, Changwen Li, Xin Ma, Yicong Chang, Chenxi Shi, Jingshan He, Rui Li, Ishfaq Muhammad & Fangping Liu. (2018) Evaluation of hepatoprotective activity of Syringa oblata leaves ethanol extract with the indicator of glutathione S -transferase A1. Revista Brasileira de Farmacognosia 28:4, pages 489-494.
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Zhenyu Shen, Yu Wang, Zhenhui Su, Ruirui Kou, Keqin Xie & Fuyong Song. (2018) Activation of p62-keap1-Nrf2 antioxidant pathway in the early stage of acetaminophen-induced acute liver injury in mice. Chemico-Biological Interactions 282, pages 22-28.
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