1,690
Views
135
CrossRef citations to date
0
Altmetric
Review Article

Zinc oxide nanoparticles impacts: cytotoxicity, genotoxicity, developmental toxicity, and neurotoxicity

Pages 300-311 | Received 17 Jun 2018, Accepted 18 Nov 2018, Published online: 16 Jan 2019

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (8)

Eun-Jung Park, Soo Nam Kim, Cheolho Yoon, Jae-Woo Cho, Gwang-Hee Lee, Dong-Wan Kim, Junhee Park, Inhee Choi, Seung Hyeun Lee, Jeongah Song, Hyun-Ji Lim, Min-Sung Kang & Hong-Soo Lee. (2021) Repeated intratracheal instillation of zinc oxide nanoparticles induced pulmonary damage and a systemic inflammatory response in cynomolgus monkeys. Nanotoxicology 15:5, pages 621-635.
Read now
Rachel Verdon, Suzanne L. Gillies, David M. Brown, Theodore Henry, Lang Tran, Charles R. Tyler, Adriano G. Rossi, Vicki Stone & Helinor J. Johnston. (2021) Neutrophil activation by nanomaterials in vitro: comparing strengths and limitations of primary human cells with those of an immortalized (HL-60) cell line. Nanotoxicology 15:1, pages 1-20.
Read now
Xia Qin, Qianghu Tang, Xuejun Jiang, Jun Zhang, Bin Wang, Xuemei Liu, Yandan Zhang, Zhen Zou & Chengzhi Chen. (2020) Zinc Oxide Nanoparticles Induce Ferroptotic Neuronal Cell Death in vitro and in vivo. International Journal of Nanomedicine 15, pages 5299-5315.
Read now
Omamuyovwi M. Ijomone, Chibuzor W. Ifenatuoha, Oritoke M. Aluko, Olayemi K. Ijomone & Michael Aschner. (2020) The aging brain: impact of heavy metal neurotoxicity. Critical Reviews in Toxicology 50:9, pages 801-814.
Read now
Victor Hugo Sousa Araujo, Jonatas Lobato Duarte, Gabriela Corrêa Carvalho, Amanda Letícia Polli Silvestre, Bruno Fonseca-Santos, Gabriel Davi Marena, Tais de Cassia Ribeiro, Matheus Aparecido dos Santos Ramos, Taís Maria Bauab & Marlus Chorilli. (2020) Nanosystems against candidiasis: a review of studies performed over the last two decades. Critical Reviews in Microbiology 46:5, pages 508-547.
Read now
Ankur Kumar Srivastava, Smriti Singh Yadav, Saumya Mishra, Sanjeev Kumar Yadav, Devendra Parmar & Sanjay Yadav. (2020) A combined microRNA and proteome profiling to investigate the effect of ZnO nanoparticles on neuronal cells. Nanotoxicology 14:6, pages 757-773.
Read now

Articles from other publishers (127)

Jia-yin Xu, P.U. Xin-Ming, De-chi Lu, Yang-yang Xing, Chen Liu, Ming Wei, Bo Wang & Jin-Fen Pan. (2023) Seawater quality criteria and ecotoxicity risk assessment of zinc oxide nanoparticles based on data of resident marine organisms in China. Science of The Total Environment 905, pages 166690.
Crossref
Magda Molenda & Joanna Kolmas. (2023) The Role of Zinc in Bone Tissue Health and Regeneration—a Review. Biological Trace Element Research 201:12, pages 5640-5651.
Crossref
Laura Jiaxuan Li, Chun-Hung Chu & Ollie Yiru Yu. (2023) Application of Zeolites and Zeolitic Imidazolate Frameworks in Dentistry—A Narrative Review. Nanomaterials 13:22, pages 2973.
Crossref
Manuel Alejandro Herrera-Rodríguez, María del Pilar Ramos-Godinez, Agustina Cano-Martínez, Francisco Correa Segura, Angélica Ruiz-Ramírez, Natalia Pavón, Elizabeth Lira-Silva, Rocío Bautista-Pérez, Rosina Sánchez Thomas, Norma Laura Delgado-Buenrostro, Yolanda Irasema Chirino & Rebeca López-Marure. (2023) Food-grade titanium dioxide and zinc oxide nanoparticles induce toxicity and cardiac damage after oral exposure in rats. Particle and Fibre Toxicology 20:1.
Crossref
Tong Chen, Lin Zhang, Liangyu Yao, Jiaochen Luan, Xiang Zhou, Rong Cong, Xuejiang Guo, Chao Qin & Ninghong Song. (2023) Zinc oxide nanoparticles-induced testis damage at single-cell resolution: Depletion of spermatogonia reservoir and disorder of Sertoli cell homeostasis. Environment International 181, pages 108292.
Crossref
Cheng Chen, Jingrong Chen, Xinpei Lin, Jiafu Yang, Huimin Qu, Lisong Li, Duanyan Zhang, Wei Wang, Xiangyu Chang, Zhenkun Guo, Ping Cai, Guangxia Yu, Wenya Shao, Hong Hu, Siying Wu, Huangyuan Li, Julia Bornhorst, Michael Aschner & Fuli Zheng. (2023) Evaluation of neurotoxicity and the role of oxidative stress of cobalt nanoparticles, titanium dioxide nanoparticles, and multiwall carbon nanotubes in Caenorhabditis elegans . Toxicological Sciences 196:1, pages 85-98.
Crossref
Kanwaljit Kaur Ahluwalia, Kritika Thakur, Amrik Singh Ahluwalia, Abeer Hashem, Graciela Dolores Avila-Quezada, Elsayed Fathi Abd_Allah & Neelam Thakur. (2023) Assessment of Genotoxicity of Zinc Oxide Nanoparticles Using Mosquito as Test Model. Toxics 11:11, pages 887.
Crossref
Dongyang Han, Renjie Chen, Haidong Kan & Yanyi Xu. (2023) The bio-distribution, clearance pathways, and toxicity mechanisms of ambient ultrafine particles. Eco-Environment & Health 2:3, pages 95-106.
Crossref
Justyna Potka-Wasylka, Małgorzata Rutkowska, Natalia Jatkowska, Malihe Zeraati, Ghasem Sargaze & Massoud Kaykhaii. 2023. Metal–Organic Frameworks in Analytical Chemistry. Metal–Organic Frameworks in Analytical Chemistry 1 44 .
Vanessa Valdiglesias, Anabel Alba-González, Natalia Fernández-Bertólez, Assia Touzani, Lucía Ramos-Pan, Ana Teresa Reis, Jorge Moreda-Piñeiro, Julián Yáñez, Blanca Laffon & Mónica Folgueira. (2023) Effects of Zinc Oxide Nanoparticle Exposure on Human Glial Cells and Zebrafish Embryos. International Journal of Molecular Sciences 24:15, pages 12297.
Crossref
Zonghong Li, Xuewei Yin, Chunyi Lyu, Teng Wang, Wenhao Wang, Jiachen Zhang, Jinxin Wang, Zhenzhen Wang, Chen Han, Ruixue Zhang, Dadong Guo & Ruirong Xu. (2023) Zinc oxide nanoparticles induce toxicity in diffuse large B-cell lymphoma cell line U2932 via activating PINK1/Parkin-mediated mitophagy.. Biomedicine & Pharmacotherapy 164, pages 114988.
Crossref
Ramsés Santacruz-Márquez, Jodi A. Flaws, Luz del Carmen Sánchez-Peña & Isabel Hernández-Ochoa. (2023) Exposure to Zinc Oxide Nanoparticles Increases Estradiol Levels and Induces an Antioxidant Response in Antral Ovarian Follicles In Vitro. Toxics 11:7, pages 602.
Crossref
Dong Qiao, Ting Zhang & Meng Tang. (2023) Autophagy regulation by inorganic, organic, and organic/inorganic hybrid nanoparticles: Organelle damage, regulation factors, and potential pathways. Journal of Biochemical and Molecular Toxicology.
Crossref
SiJia Geng, PengFei Hao, Di Wang, Pengfei Zhong, Fangfang Tian, Rui Zhang, Juan Qiao, Xiaochen Qiu & Pengtao Bao. (2023) Zinc oxide nanoparticles have biphasic roles on Mycobacterium-induced inflammation by activating autophagy and ferroptosis mechanisms in infected macrophages. Microbial Pathogenesis 180, pages 106132.
Crossref
Qiong Li, Yajing Feng, Ruike Wang, Rundong Liu, Yue Ba & Hui Huang. (2023) Recent insights into autophagy and metals/nanoparticles exposure. Toxicological Research 39:3, pages 355-372.
Crossref
Chaman Ara, Shagufta Andleeb, Shaukat Ali, Barirah Majeed, Asia Iqbal, Madeeha Arshad, Asma Chaudhary, Asmatullah & Aliza Muzamil. (2023) Protective potential of fresh orange juice against zinc oxide nanoparticles‐induced trans‐placental and trans‐generational toxicity in mice. Food Science & Nutrition.
Crossref
Ankita Gauba, Sharath Kumar Hari, Vellaisamy Ramamoorthy, Shanmugaiah Vellasamy, Ganesan Govindan & M. Valan Arasu. (2023) The versatility of green synthesized zinc oxide nanoparticles in sustainable agriculture: A review on metal-microbe interaction that rewards agriculture. Physiological and Molecular Plant Pathology 125, pages 102023.
Crossref
Boyun Kim, Gaeun Kim, Soyeon Jeon, Wan-Seob Cho, Hyun Pyo Jeon & Jewon Jung. (2023) Zinc Oxide Nanoparticles Trigger Autophagy-mediated Cell Death through Activating Lysosomal TRPML1 in Normal Kidney Cells. Toxicology Reports.
Crossref
Yaxin Tang, Lifang Jin, Wenwen Qi, Yue Gao, Yixia Xie, Xueying Xie, Jianan Lv, Zhikai Jiang, He Jiang, Caixia Fan & Junyan Yan. (2023) N-acetyl-L-cysteine attenuated the toxicity of ZIF-8 on EA.hy926 endothelial cells by wnt/β-catenin pathway. Toxicology in Vitro 88, pages 105553.
Crossref
Chengxi Li, Yapeng Han, Tiantian Gao, Jun Zhang, De-Xiang Xu & Yán Wāng. (2022) Insecticidal activity of metallic nanopesticides synthesized from natural resources: A review. Environmental Chemistry Letters 21:2, pages 1141-1176.
Crossref
Junko Fujihara & Naoki Nishimoto. (2023) Review of Zinc Oxide Nanoparticles: Toxicokinetics, Tissue Distribution for Various Exposure Routes, Toxicological Effects, Toxicity Mechanism in Mammals, and an Approach for Toxicity Reduction. Biological Trace Element Research.
Crossref
Lan Zhao, Shuyuan Wang, Marit Ilves, Sanna Lehtonen, Leena Saikko, Hani El-Nezami, Harri Alenius & Piia Karisola. (2023) Transcriptomic Profiling the Effects of Airway Exposure of Zinc Oxide and Silver Nanoparticles in Mouse Lungs. International Journal of Molecular Sciences 24:6, pages 5183.
Crossref
Avnika Singh Anand, Khushbu Jain, Amitabh Chauhan, Dipti N Prasad & Ekta Kohli. (2023) Zinc oxide nanoparticles trigger dysfunction of mitochondrial respiratory complexes and repair dynamics in human alveolar cells. Toxicology and Industrial Health 39:3, pages 127-137.
Crossref
Alyse N. Peters, Nakaja A. Weaver, Kathryn S. Monahan & Kyoungtae Kim. (2023) Non-ROS-Mediated Cytotoxicity of ZnO and CuO in ML-1 and CA77 Thyroid Cancer Cell Lines. International Journal of Molecular Sciences 24:4, pages 4055.
Crossref
Jacquelyn Cheng, Nikolai Kolba, Alba García-Rodríguez, Cláudia N. H. Marques, Gretchen J. Mahler & Elad Tako. (2023) Food-Grade Metal Oxide Nanoparticles Exposure Alters Intestinal Microbial Populations, Brush Border Membrane Functionality and Morphology, In Vivo (Gallus gallus). Antioxidants 12:2, pages 431.
Crossref
Lingbing Zhang, Yandan Zhang, Xuejun Jiang, Lejiao Mao, Yinyin Xia, Yinzhen Fan, Na Li, Ziqi Jiang, Xia Qin, Yu Jiang, Gang Liu, Feng Qiu, Jun Zhang, Zhen Zou & Chengzhi Chen. (2023) Disruption of the lung-gut-brain axis is responsible for cortex damage induced by pulmonary exposure to zinc oxide nanoparticles. Toxicology 485, pages 153390.
Crossref
Liangliang Liu, Junkang Wang, Jiaqi Zhang, Chaobo Huang, Zhaogang Yang & Yi Cao. (2021) The cytotoxicity of zinc oxide nanoparticles to 3D brain organoids results from excessive intracellular zinc ions and defective autophagy. Cell Biology and Toxicology 39:1, pages 259-275.
Crossref
Wei Juene Chong, Shirley Shen, Yuncang Li, Adrian Trinchi, Dejana Pejak Simunec, Ilias (Louis) Kyratzis, Antonella Sola & Cuie Wen. (2023) Biodegradable PLA-ZnO nanocomposite biomaterials with antibacterial properties, tissue engineering viability, and enhanced biocompatibility. Smart Materials in Manufacturing 1, pages 100004.
Crossref
Xingyao Pei, Haiyang Jiang, Cun Li, Daowen Li & Shusheng Tang. (2023) Oxidative stress-related canonical pyroptosis pathway, as a target of liver toxicity triggered by zinc oxide nanoparticles. Journal of Hazardous Materials 442, pages 130039.
Crossref
Liying Dong, Shutao Wang, Lin Zhang, Dongmei Liu & Hong You. (2023) DBDPE and ZnO NPs synergistically induce neurotoxicity of SK-N-SH cells and activate mitochondrial apoptosis signaling pathway and Nrf2-mediated antioxidant pathway. Journal of Hazardous Materials 441, pages 129872.
Crossref
Meimei Wang, Yu Feng, Zhenxiao Cao, Na Yu, Juan Wang, Xiaowei Wang, Dixiang Kang, Mingqin Su, Jian Hu & Hua Du. (2023) Multiple generation exposure to ZnO nanoparticles induces loss of genomic integrity in Caenorhabditis elegans. Ecotoxicology and Environmental Safety 249, pages 114383.
Crossref
Fernanda Toscano & Marbel Torres-Arias. (2023) Nanoparticles cellular uptake, trafficking, activation, toxicity and in vitro evaluation. Current Research in Immunology 4, pages 100073.
Crossref
Kuldeep Rajpoot, Muktika Tekade, Bhakti Pawar, Nupur Vasdev, Tanisha Gupta & Rakesh Kumar Tekade. 2023. Essentials of Pharmatoxicology in Drug Research, Volume 1. Essentials of Pharmatoxicology in Drug Research, Volume 1 551 574 .
Luís Marcos Cerdeira Ferreira & Fernando Campanhã Vicentini. 2023. Agricultural and Environmental Nanotechnology. Agricultural and Environmental Nanotechnology 489 524 .
Deepak Rohilla & Savita Chaudhary. 2023. Advanced Functional Nanoparticles "Boon or Bane" for Environment Remediation Applications. Advanced Functional Nanoparticles "Boon or Bane" for Environment Remediation Applications 27 74 .
Elizaveta S. Permyakova, Anton M. Manakhov, Philipp V. Kiryukhantsev-Korneev, Denis V. Leybo, Anton S. Konopatsky, Yulia A. Makarets, Svetlana Yu. Filippovich, Sergey G. Ignatov & Dmitry V. Shtansky. (2022) Electrospun Polycaprolactone/ZnO Nanocomposite Membranes with High Antipathogen Activity. Polymers 14:24, pages 5364.
Crossref
Muhammad Musaddiq Shah, Khurshid Ahmad, Bashir Ahmad, Shahid Masood Shah, Hamid Masood, Muhammad Aamir Ramzan Siddique & Rasheed Ahmad. (2022) Recent trends in green synthesis of silver, gold, and zinc oxide nanoparticles and their application in nanosciences and toxicity: a review. Nanotechnology for Environmental Engineering 7:4, pages 907-922.
Crossref
Rafaela Miranda Barbosa, Malu Mateus Santos Obata, José Rodrigues do Carmo Neto, Rhanoica Oliveira Guerra, Anna Victória Bernardes e Borges, Rafael Obata Trevisan, Letícia Cirelli Ruiz, Júlia de Moura Bernardi, Ana Carolina de Morais Oliveira-Scussel, Sarah Cristina Sato Vaz Tanaka, Fernanda Bernadelli de Vito, Fernanda Rodrigues Helmo, Thaís Soares Farnesi de Assunção, Juliana Reis Machado, Carlo José Freire de Oliveira, Virmondes Rodrigues Júnior, Anielle Christine Almeida Silva & Marcos Vinicius da Silva. (2022) Development of Ag-ZnO/AgO Nanocomposites Effectives for Leishmania braziliensis Treatment. Pharmaceutics 14:12, pages 2642.
Crossref
Rajashri Bezbaruah, Vivek P. Chavda, Lawandashisha Nongrang, Shahnaz Alom, Kangkan Deka, Tutumoni Kalita, Farak Ali, Bedanta Bhattacharjee & Lalitkumar Vora. (2022) Nanoparticle-Based Delivery Systems for Vaccines. Vaccines 10:11, pages 1946.
Crossref
Dewei Qiu, Ping Zhou, Jiawei Kang, Zhijun Chen, Zhiyong Xu, Hanwen Yang, Jun Tao & Fanrong Ai. (2022) ZnO nanoparticle modified chitosan/borosilicate bioglass composite scaffold for inhibiting bacterial infection and promoting bone regeneration. Biomedical Materials 17:6, pages 065023.
Crossref
Radwa Sehsah, Wenting Wu, Sahoko Ichihara, Naozumi Hashimoto, Cai Zong, Kyoka Yamazaki, Harue Sato, Ken Itoh, Masayuki Yamamoto, Ahmed Ali Elsayed, Soheir El-Bestar, Emily Kamel & Gaku Ichihara. (2022) Protective role of Nrf2 in zinc oxide nanoparticles-induced lung inflammation in female mice and sexual dimorphism in susceptibility. Toxicology Letters 370, pages 24-34.
Crossref
Zheng Wang, Xing Li, Shaohua Du, Xiaoshan Sun, Jianguo Huang & Yuxin Shao. (2022) Protective Effects of Zinc on Salmonella Invasion, Intestinal Morphology and Immune Response of Young Pigeons Infected with Salmonella enterica Serovar Typhimurium. Biological Trace Element Research 200:11, pages 4817-4827.
Crossref
Eman Zakaria Gomaa. (2022) Microbial Mediated Synthesis of Zinc Oxide Nanoparticles, Characterization and Multifaceted Applications. Journal of Inorganic and Organometallic Polymers and Materials 32:11, pages 4114-4132.
Crossref
Criselda Mendoza-Milla, Fernanda Isabel Macías Macías, Kimberly Abigail Velázquez Delgado, Manuel Alejandro Herrera Rodríguez, Zaira Colín-Val, María del Pilar Ramos-Godinez, Agustina Cano-Martínez, Anita Vega-Miranda, Diana Xochiquetzal Robledo-Cadena, Norma Laura Delgado-Buenrostro, Yolanda Irasema Chirino, José Ocotlán Flores-Flores & Rebeca López-Marure. (2022) Zinc Oxide Nanoparticles Induce Toxicity in H9c2 Rat Cardiomyoblasts. International Journal of Molecular Sciences 23:21, pages 12940.
Crossref
Massimo Aloisi, Gianna Rossi, Sabrina Colafarina, Maurizio Guido, Sandra Cecconi & Anna M. G. Poma. (2022) The Impact of Metal Nanoparticles on Female Reproductive System: Risks and Opportunities. International Journal of Environmental Research and Public Health 19:21, pages 13748.
Crossref
Mei Li, Yonghua Ma, Xiaodi Lian, Yan Lu, Yuanyuan Li, Yao Xi & Xiaolin Sun. (2022) Study on the biological effects of ZnO nanosheets on EBL cells. Frontiers in Bioengineering and Biotechnology 10.
Crossref
Ionelia Taranu, Gina Cecilia Pistol, Andrei Cristian Anghel, Daniela Marin & Cristina Bulgaru. (2022) Yeast-Fermented Rapeseed Meal Extract Is Able to Reduce Inflammation and Oxidative Stress Caused by Escherichia coli Lipopolysaccharides and to Replace ZnO in Caco-2/HTX29 Co-Culture Cells. International Journal of Molecular Sciences 23:19, pages 11640.
Crossref
Yiru Niu & Meng Tang. (2022) In vitro review of nanoparticles attacking macrophages: Interaction and cell death. Life Sciences 307, pages 120840.
Crossref
Hanieh Shokrani, Amirhossein Shokrani, S. Mohammad Sajadi, Mohsen Khodadadi Yazdi, Farzad Seidi, Maryam Jouyandeh, Payam Zarrintaj, Saptarshi Kar, Seok-Jhin Kim, Tairong Kuang, Navid Rabiee, Alexander Hejna, Mohammad Reza Saeb & Seeram Ramakrishna. (2022) Polysaccharide-based nanocomposites for biomedical applications: a critical review. Nanoscale Horizons 7:10, pages 1136-1160.
Crossref
Andreya Gonçalves Costa Motta, Vinicius Guerra, Diogo Ferreira do Amaral, Amanda Pereira da Costa Araújo, Lucélia Gonçalves Vieira, Daniela de Melo e Silva & Thiago Lopes Rocha. (2022) Assessment of multiple biomarkers in Lithobates catesbeianus (Anura: Ranidae) tadpoles exposed to zinc oxide nanoparticles and zinc chloride: integrating morphological and behavioral approaches to ecotoxicology. Environmental Science and Pollution Research 30:5, pages 13755-13772.
Crossref
Renkai Wang, Yanli Ren, Hafiz Umer Javad, Jieer Luo, Meng Zhou & Xugang Shu. (2022) Effect of Different Dietary Zinc Sources on Growth, Element Deposition, Antioxidation, Lipid Metabolism, and Related Gene Expression in Hybrid Grouper (♀ Epinephelus fuscoguttatus × ♂ E. lanceolatus). Aquaculture Nutrition 2022, pages 1-11.
Crossref
Jiayin Wang, Xiaolin Zhu, Liju Tan, Ting Zhao, Ziqi Ni, Na Zhang & Jiangtao Wang. (2022) Single and combined nanotoxicity of ZnO nanoparticles and graphene quantum dots against the microalga Heterosigma akashiwo . Environmental Science: Nano 9:8, pages 3094-3109.
Crossref
Liwei Wang, Zhiyu Duan, Madan Liang, Chunqiang Wang, Tingting Liang, Liqian Sun, Chaoqun Yan, Qingshan Li & Taigang Liang. (2022) A pivotal role of selective autophagy in mitochondrial quality control: Implications for zinc oxide nanoparticles induced neurotoxicity. Chemico-Biological Interactions 363, pages 110003.
Crossref
Shana J. Cameron, Jessica Sheng, Farah Hosseinian & William G. Willmore. (2022) Nanoparticle Effects on Stress Response Pathways and Nanoparticle–Protein Interactions. International Journal of Molecular Sciences 23:14, pages 7962.
Crossref
Poonam Yadav, Chandan Chauhan, Sanjiv Singh, Sugato Banerjee & Krishna Murti. (2022) β-sitosterol in Various Pathological Conditions: An Update. Current Bioactive Compounds 18:6.
Crossref
Gabriel Davi Marena, Matheus Aparecido dos Santos Ramos, Gabriela Corrêa Carvalho, José Alberto Paris Junior, Flávia Aparecida Resende, Ione Corrêa, Gabriela Yuki Bressanim Ono, Victor Hugo Sousa Araujo, Bruna Almeida Furquim de Camargo, Tais Maria Bauab & Marlus Chorilli. (2022) Natural product‐based nanomedicine applied to fungal infection treatment: A review of the last 4 years. Phytotherapy Research 36:7, pages 2710-2745.
Crossref
Fuli Zheng, Cheng Chen & Michael Aschner. (2022) Neurotoxicity Evaluation of Nanomaterials Using C. elegans : Survival, Locomotion Behaviors, and Oxidative Stress . Current Protocols 2:7.
Crossref
Ghasem Rahimi, Kalateh Shah Mohammad, Mahsa Zarei, Mohammad Shokoohi, Ehsan Oskoueian, Mahsa Rastegar Moghaddam Poorbagher & Ehsan Karimi. (2022) Zinc oxide nanoparticles synthesized using Hyssopus Officinalis L. Extract Induced oxidative stress and changes the expression of key genes involved in inflammatory and antioxidant Systems. Biological Research 55:1.
Crossref
Kumaran Subramanian, Deivasigamani Balaraman, Kumaravel Kaliyaperumal, V. Devi Rajeswari, K. Balakrishnan, P. Ronald Ross, Elumalai Perumal, Pugazhvendan Sampath Renuga, Mani Panangal, Y. Swarnalatha & S. Velmurugan. (2022) Preparation of an Intelligent pH Film Based on Biodegradable Polymers for Monitoring the Food Quality and Reducing the Microbial Contaminants. Bioinorganic Chemistry and Applications 2022, pages 1-12.
Crossref
Xingyao Pei, Haiyang Jiang, Gang Xu, Cun Li, Daowen Li & Shusheng Tang. (2022) Lethality of Zinc Oxide Nanoparticles Surpasses Conventional Zinc Oxide via Oxidative Stress, Mitochondrial Damage and Calcium Overload: A Comparative Hepatotoxicity Study. International Journal of Molecular Sciences 23:12, pages 6724.
Crossref
Olga Klaudia Szewczyk, Piotr Roszczenko, Robert Czarnomysy, Anna Bielawska & Krzysztof Bielawski. (2022) An Overview of the Importance of Transition-Metal Nanoparticles in Cancer Research. International Journal of Molecular Sciences 23:12, pages 6688.
Crossref
Andrey Boyadzhiev, Silvia Aidee Solorio-Rodriguez, Dongmei Wu, Mary-Luyza Avramescu, Pat Rasmussen & Sabina Halappanavar. (2022) The High-Throughput In Vitro CometChip Assay for the Analysis of Metal Oxide Nanomaterial Induced DNA Damage. Nanomaterials 12:11, pages 1844.
Crossref
Julia Higuchi, Katarzyna Klimek, Jacek Wojnarowicz, Agnieszka Opalińska, Agnieszka Chodara, Urszula Szałaj, Sylwia Dąbrowska, Damian Fudala & Grazyna Ginalska. (2022) Electrospun Membrane Surface Modification by Sonocoating with HA and ZnO:Ag Nanoparticles—Characterization and Evaluation of Osteoblasts and Bacterial Cell Behavior In Vitro. Cells 11:9, pages 1582.
Crossref
Sanjiv Singh, Upendr Gautam & F. V. Manvi. (2020) Protective Impact of Edaravone Against ZnO NPs-induced Oxidative Stress in the Human Neuroblastoma SH-SY5Y Cell Line. Cellular and Molecular Neurobiology 42:4, pages 1189-1210.
Crossref
José Rodrigues do Carmo Neto, Rhanoica Oliveira Guerra, Juliana Reis Machado, Anielle Christine Almeida Silva & Marcos Vinicius da Silva. (2022) Antiprotozoal and Anthelmintic Activity of Zinc Oxide Nanoparticles. Current Medicinal Chemistry 29:12, pages 2127-2141.
Crossref
Agnese Bregnocchi, Reza Jafari & Gelareh Momen. (2022) Design strategies for antiviral coatings and surfaces: A review. Applied Surface Science Advances 8, pages 100224.
Crossref
Łukasz Łopusiewicz, Szymon Macieja, Mariusz Śliwiński, Artur Bartkowiak, Swarup Roy & Peter Sobolewski. (2022) Alginate Biofunctional Films Modified with Melanin from Watermelon Seeds and Zinc Oxide/Silver Nanoparticles. Materials 15:7, pages 2381.
Crossref
Mohammad Imran, Saurav Kumar Jha, Nazeer Hasan, Areeba Insaf, Jitendra Shrestha, Jesus Shrestha, Hari Prasad Devkota, Salman Khan, Nisha Panth, Majid Ebrahimi Warkiani, Kamal Dua, Philip M. Hansbro, Keshav Raj Paudel & Yousuf Mohammed. (2022) Overcoming Multidrug Resistance of Antibiotics via Nanodelivery Systems. Pharmaceutics 14:3, pages 586.
Crossref
А.Л. Верещагин & Е.А. Морозова. (2022) SPECIFIC TOXICITY OF NANOPARTICLES (REVIEW). Южно-Сибирский научный вестник:1(41), pages 76-88.
Crossref
Van Anh Thi Le, Tung X. Trinh, Pham Ngoc Chien, Nguyen Ngan Giang, Xin-Rui Zhang, Sun-Young Nam & Chan-Yeong Heo. (2022) Evaluation of the Performance of a ZnO-Nanoparticle-Coated Hydrocolloid Patch in Wound Healing. Polymers 14:5, pages 919.
Crossref
Vancha Harish, Devesh Tewari, Manish Gaur, Awadh Bihari Yadav, Shiv Swaroop, Mikhael Bechelany & Ahmed Barhoum. (2022) Review on Nanoparticles and Nanostructured Materials: Bioimaging, Biosensing, Drug Delivery, Tissue Engineering, Antimicrobial, and Agro-Food Applications. Nanomaterials 12:3, pages 457.
Crossref
Anna Mittag, Patricia Owesny, Christian Hoera, Alexander Kämpfe & Michael Glei. (2022) Effects of Zinc Oxide Nanoparticles on Model Systems of the Intestinal Barrier. Toxics 10:2, pages 49.
Crossref
Abdulkader Shaikh Omar. (2022) Nanoformulation Safety versus Toxicity; What do the Recent Studies Tell Us?. International Journal of Pharmaceutical Research And Allied Sciences 11:4, pages 60-71.
Crossref
Danyu Lv, Wenqian Nong & Yongguang Guan. (2022) Edible ligand-metal-organic frameworks: Synthesis, structures, properties and applications. Coordination Chemistry Reviews 450, pages 214234.
Crossref
Periklis Vardakas, Ioannis D. Kyriazis, Maria Kourti, Zoi Skaperda, Fotios Tekos & Demetrios Kouretas. 2022. Advanced Nanomaterials and Their Applications in Renewable Energy. Advanced Nanomaterials and Their Applications in Renewable Energy 179 218 .
Tejal Mehta, Dhaivat Parikh, Kartik Hariharan, Namdev Dhas & Viral Patel. 2021. Nanotechnology in Medicine. Nanotechnology in Medicine 109 136 .
Fatma ÜNAL, Funda DEMIRTAŞ KORKMAZ, Zekiye SULUDERE, Özlem EROL & Deniz YÜZBAŞIOĞLU. (2021) Genotoxicity of Two Nanoparticles: Titanium Dioxide and Zinc Oxide. Gazi University Journal of Science 34:4, pages 948-958.
Crossref
Lan-Min Wang, Yu-Ting Wang & Wan-Xi Yang. (2021) Engineered nanomaterials induce alterations in biological barriers: focus on paracellular permeability. Nanomedicine 16:30, pages 2725-2741.
Crossref
Sofía Navarro Espinoza, Diana Meza-Figueroa, Diego Soto-Puebla, Beatriz Castañeda & Martín Pedroza-Montero. (2021) NANOPARTÍCULAS: EFECTOS EN LA SALUD HUMANA Y EL MEDIO AMBIENTE. EPISTEMUS 15:30.
Crossref
Anneke Dixie Kakebeen & Lee Niswander. (2021) Micronutrient imbalance and common phenotypes in neural tube defects. genesis 59:11.
Crossref
Vinod Paul, Sreelakshmi Krishnakumar, Genekehal Siddaramana Gowd, Shantikumar V. Nair, Manzoor Koyakutty & Bindhu Paul-Prasanth. (2021) Sex-Dependent Bioaccumulation of Nano Zinc Oxide and Its Adverse Effects on Sexual Behavior and Reproduction in Japanese Medaka. ACS Applied Bio Materials 4:10, pages 7408-7421.
Crossref
Maryam Farokhcheh, Leilabeigom Hejazian, Zeinab Akbarnejad, Fereshteh Pourabdolhossein, Seyed Mohammad Hosseini, Tahereh Mohammad Mehraei & Nabiollah Soltanpour. (2021) Geraniol improved memory impairment and neurotoxicity induced by zinc oxide nanoparticles in male wistar rats through its antioxidant effect. Life Sciences 282, pages 119823.
Crossref
Ritesh K Shukla, Ashish Badiye, Kamayani Vajpayee & Neeti Kapoor. (2021) Genotoxic Potential of Nanoparticles: Structural and Functional Modifications in DNA. Frontiers in Genetics 12.
Crossref
Wei Du, Yiru Gao, Li Liu, Sixiang Sai & Chen Ding. (2021) Striking Back against Fungal Infections: The Utilization of Nanosystems for Antifungal Strategies. International Journal of Molecular Sciences 22:18, pages 10104.
Crossref
Željko Janićijević, Ana Stanković, Bojana Žegura, Đorđe Veljović, Ljiljana Djekić, Danina Krajišnik, Metka Filipič & Magdalena M. Stevanović. (2021) Safe-by-design gelatin-modified zinc oxide nanoparticles. Journal of Nanoparticle Research 23:9.
Crossref
Victor García-Torra, Amanda Cano, Marta Espina, Miren Ettcheto, Antoni Camins, Emma Barroso, Manel Vazquez-Carrera, Maria Luisa García, Elena Sánchez-López & Eliana B. Souto. (2021) State of the Art on Toxicological Mechanisms of Metal and Metal Oxide Nanoparticles and Strategies to Reduce Toxicological Risks. Toxics 9:8, pages 195.
Crossref
Xiaojun Tao, Siyu Mao, Qiufang Zhang, Hongyuan Yu, Yu Li, Xiangling He, Shanyi Yang, Zhirong Zhang, Ziqi Yi, Yujiao Song & Xing Feng. (2021) Brain-Targeted Polysorbate 80-Emulsified Donepezil Drug-Loaded Nanoparticles for Neuroprotection. Nanoscale Research Letters 16:1.
Crossref
Joanna Jabłońska, Magdalena Onyszko, Maciej Konopacki, Adrian Augustyniak, Rafał Rakoczy & Ewa Mijowska. (2021) Fabrication of Paper Sheets Coatings Based on Chitosan/Bacterial Nanocellulose/ZnO with Enhanced Antibacterial and Mechanical Properties. International Journal of Molecular Sciences 22:14, pages 7383.
Crossref
Yu Yan, Guang Wang, Xin Luo, Ping Zhang, Shuang Peng, Xin Cheng, Mengwei Wang & Xuesong Yang. (2021) Endoplasmic reticulum stress-related calcium imbalance plays an important role on Zinc oxide nanoparticles-induced failure of neural tube closure during embryogenesis. Environment International 152, pages 106495.
Crossref
Qian Zhang, Tao Wu, Siyuan Li, Yuxuan Meng, Zihan Tan, Mengjun Wu, Dan Yi, Lei Wang, Di Zhao & Yongqing Hou. (2021) Protective Effect of Zinc Oxide and Its Association with Neutrophil Degranulation in Piglets Infected with Porcine Epidemic Diarrhea Virus. Oxidative Medicine and Cellular Longevity 2021, pages 1-12.
Crossref
Anielle C.A. Silva, Jerusa M. de Oliveira, Luciana R.S. Floresta, Matheus V. da Silva, José L. da S. Duarte, Karolina B. da Silva, Eurípedes A. da Silva Filho, Vinícius P. Bittar, Ana L.S. Borges, Guilherme L. Fernandes, Alessandra S. Silva, Éder V. Guimarães, Ricardo S. Silva, Carmem L.P.S. Zanta, Lucas Anhezini & Noelio O. Dantas. 2021. Transition Metal Compounds - Synthesis, Properties, and Application. Transition Metal Compounds - Synthesis, Properties, and Application.
Natalia Wrońska, Nadia Katir, Katarzyna Miłowska, Nisrine Hammi, Marta Nowak, Marta Kędzierska, Aicha Anouar, Katarzyna Zawadzka, Maria Bryszewska, Abdelkrim El Kadib & Katarzyna Lisowska. (2021) Antimicrobial Effect of Chitosan Films on Food Spoilage Bacteria. International Journal of Molecular Sciences 22:11, pages 5839.
Crossref
Seyyed Vahid Mousazad Goorabjavari, Fateme Golmohamadi, Saba Haririmonfared, Hosein Ahmadi, Soheil Golisani, Hadi Yari, Anwarul Hasan, Zehra Edis, Mahsa Ale-Ebrahim, Majid Sharifi, Behnam Rasti, Fahimeh Nemati & Mojtaba Falahati. (2021) Thermodynamic and anticancer properties of inorganic zinc oxide nanoparticles synthesized through co-precipitation method. Journal of Molecular Liquids 330, pages 115602.
Crossref
Ali Pormohammad, Nadia K. Monych, Sougata Ghosh, Diana L. Turner & Raymond J. Turner. (2021) Nanomaterials in Wound Healing and Infection Control. Antibiotics 10:5, pages 473.
Crossref
Ehsan Nazarzadeh Zare, Xuanqi Zheng, Pooyan Makvandi, Homa Gheybi, Rossella Sartorius, Cynthia K. Y. Yiu, Mohsen Adeli, Aimin Wu, Ali Zarrabi, Rajender S. Varma & Franklin R. Tay. (2021) Nonspherical Metal‐Based Nanoarchitectures: Synthesis and Impact of Size, Shape, and Composition on Their Biological Activity. Small 17:17, pages 2007073.
Crossref
Samantha V. Llewellyn, Marije Niemeijer, Penny Nymark, Martijn J. Moné, Bob van de Water, Gillian E. Conway, Gareth J. S. Jenkins & Shareen H. Doak. (2021) In Vitro Three‐Dimensional Liver Models for Nanomaterial DNA Damage Assessment. Small 17:15.
Crossref
Andrea Bonetti, Benedetta Tugnoli, Andrea Piva & Ester Grilli. (2021) Towards Zero Zinc Oxide: Feeding Strategies to Manage Post-Weaning Diarrhea in Piglets. Animals 11:3, pages 642.
Crossref
Atsuko Miyajima, Tsuyoshi Kawakami, Kaoru Komoriya, Reiko Kato, Makoto Usami & Kazuo Isama. (2021) Potency shift in immunomodulatory activities of zinc oxide (ZnO) nanoparticles in THP-1 cells is associated with cytotoxicity. Fundamental Toxicological Sciences 8:7, pages 205-213.
Crossref
Muhammad Irfan Sohail, Muhammad Ashar Ayub, Muhammad Zia ur Rehman, Muhammad Azhar, Zia Ur Rahman Farooqi, Ayesha Siddiqui, Wajid Umar, Irfan Iftikhar, Muhammad Nadeem & Hina Fatima. 2021. Nanomaterials: Synthesis, Characterization, Hazards and Safety. Nanomaterials: Synthesis, Characterization, Hazards and Safety 145 221 .
Suseelendra Desai, Saaketh Desai, John Peter, G. Praveen Kumar & Leo Daniel Amalraj. 2021. Zinc-Based Nanostructures for Environmental and Agricultural Applications. Zinc-Based Nanostructures for Environmental and Agricultural Applications 589 629 .
Zixuan Liu, Xuying Lv, Lei Xu, Xuting Liu, Xiangyu Zhu, Erqun Song & Yang Song. (2020) Zinc oxide nanoparticles effectively regulate autophagic cell death by activating autophagosome formation and interfering with their maturation. Particle and Fibre Toxicology 17:1.
Crossref
Andreya Gonçalves Costa Motta, Diogo Ferreira do Amaral, Marcelino Benvindo-Souza, Thiago Lopes Rocha & Daniela de Melo e Silva. (2020) Genotoxic and mutagenic effects of zinc oxide nanoparticles and zinc chloride on tadpoles of Lithobates catesbeianus (Anura: Ranidae). Environmental Nanotechnology, Monitoring & Management 14, pages 100356.
Crossref
Ackmez Mudhoo, Sonam Paliya, Prittam Goswami, Mukesh Singh, Giusy Lofrano, Maurizio Carotenuto, Federica Carraturo, Giovanni Libralato, Marco Guida, Muhammad Usman & Sunil Kumar. (2020) Fabrication, functionalization and performance of doped photocatalysts for dye degradation and mineralization: a review. Environmental Chemistry Letters 18:6, pages 1825-1903.
Crossref
Miko Yamada, Lynlee L. Lin, Lydia Y.T. Hang, Paul J. Belt, H. Peter Soyer, Anthony P. Raphael & Tarl W. Prow. (2020) A minimally invasive clinical model to test sunscreen toxicity based on oxidative stress levels using microbiopsy and confocal microscopy – a proof of concept study. International Journal of Cosmetic Science 42:5, pages 462-470.
Crossref
Muammar Mansor & Jie Xu. (2020) Benefits at the nanoscale: a review of nanoparticle‐enabled processes favouring microbial growth and functionality . Environmental Microbiology 22:9, pages 3633-3649.
Crossref
Ramsés Santacruz-Márquez, Aidee Solorio-Rodríguez, Sirenia González-Posos, Sihomara Patricia García-Zepeda, Jaime Santoyo-Salazar, Andrea De Vizcaya-Ruiz & Isabel Hernández-Ochoa. (2020) Comparative effects of TiO2 and ZnO nanoparticles on growth and ultrastructure of ovarian antral follicles. Reproductive Toxicology 96, pages 399-412.
Crossref
Bolu Chen, Wuding Hong, Yizhou Tang, Yu Zhao, Zoraida P. Aguilar & Hengyi Xu. (2020) Protective effect of the NAC and Sal on zinc oxide nanoparticles-induced reproductive and development toxicity in pregnant mice. Food and Chemical Toxicology 143, pages 111552.
Crossref
Yu. M. Harmaza, A. V. Tamashevski & E. I. Slobozhanina. (2020) Molecular nature of cytotoxicity of zinc oxide nanostructures. Doklady of the National Academy of Sciences of Belarus 64:4, pages 448-456.
Crossref
Aurica Precupas, Daniela Gheorghe, Alina Botea-Petcu, Anca Ruxandra Leonties, Romica Sandu, Vlad Tudor Popa, Espen Mariussen, El Yamani Naouale, Elise Rundén-Pran, Veronica Dumit, Ying Xue, Mihaela Roxana Cimpan, Maria Dusinska, Andrea Haase & Speranta Tanasescu. (2020) Thermodynamic Parameters at Bio–Nano Interface and Nanomaterial Toxicity: A Case Study on BSA Interaction with ZnO, SiO 2 , and TiO 2 . Chemical Research in Toxicology 33:8, pages 2054-2071.
Crossref
Jian Meng, Xiaoling Zhou, Juan Yang, Xianjun Qu & Shuxiang Cui. (2020) Exposure to low dose ZnO nanoparticles induces hyperproliferation and malignant transformation through activating the CXCR2/NF-κB/STAT3/ERK and AKT pathways in colonic mucosal cells. Environmental Pollution 263, pages 114578.
Crossref
Yun Qian, Yuan Cheng, Jialin Song, Yang Xu, Wei‐En Yuan, Cunyi Fan & Xianyou Zheng. (2020) Mechano‐Informed Biomimetic Polymer Scaffolds by Incorporating Self‐Powered Zinc Oxide Nanogenerators Enhance Motor Recovery and Neural Function. Small 16:32, pages 2000796.
Crossref
Seval BAL & Nazmiye Özlem ŞANLI. (2020) İç mekan hijyen koşullarının arttırılmasında antibakteriyel duvar boyasının etkinliğinin değerlendirilmesi. Gazi Üniversitesi Mühendislik Mimarlık Fakültesi Dergisi 35:4, pages 1913-1922.
Crossref
Rebeka Rudolf, Danica Popović, Sergej Tomić, Rajko Bobovnik, Vojkan Lazić, Peter Majerič, Ivan Anžel & Miodrag Čolić. (2020) Microstructure Characterisation and Identification of the Mechanical and Functional Properties of a New PMMA-ZnO Composite. Materials 13:12, pages 2717.
Crossref
Luisa Racca, Tania Limongi, Veronica Vighetto, Bianca Dumontel, Andrea Ancona, Marta Canta, Giancarlo Canavese, Nadia Garino & Valentina Cauda. (2020) Zinc Oxide Nanocrystals and High-Energy Shock Waves: A New Synergy for the Treatment of Cancer Cells. Frontiers in Bioengineering and Biotechnology 8.
Crossref
Jacek Wojnarowicz, Tadeusz Chudoba & Witold Lojkowski. (2020) A Review of Microwave Synthesis of Zinc Oxide Nanomaterials: Reactants, Process Parameters and Morphologies. Nanomaterials 10:6, pages 1086.
Crossref
Roberta Giordo, Gheyath K. Nasrallah, Ola Al-Jamal, Panagiotis Paliogiannis & Gianfranco Pintus. (2020) Resveratrol Inhibits Oxidative Stress and Prevents Mitochondrial Damage Induced by Zinc Oxide Nanoparticles in Zebrafish (Danio rerio). International Journal of Molecular Sciences 21:11, pages 3838.
Crossref
Yu Yan, Guang Wang, Ju Huang, Yan Zhang, Xin Cheng, Manli Chuai, Beate Brand-Saberi, Guobing Chen, Xiaohua Jiang & Xuesong Yang. (2020) Zinc oxide nanoparticles exposure-induced oxidative stress restricts cranial neural crest development during chicken embryogenesis. Ecotoxicology and Environmental Safety 194, pages 110415.
Crossref
Ana Rita Pinho, Filipa Martins, M. Elisabete V. Costa, Ana M. R. Senos, Odete A. B. da Cruz e Silva, Maria de Lourdes Pereira & Sandra Rebelo. (2020) In Vitro Cytotoxicity Effects of Zinc Oxide Nanoparticles on Spermatogonia Cells. Cells 9:5, pages 1081.
Crossref
Daria Wehlage, Hannah Blattner, Al Mamun, Ines Kutzli, Elise Diestelhorst, Anke Rattenholl, Frank Gudermann, Dirk Lütkemeyer & Andrea Ehrmann. (2020) Cell growth on electrospun nanofiber mats from polyacrylonitrile (PAN) blends. AIMS Bioengineering 7:1, pages 43-54.
Crossref
Ewa Sawicka, Arkadiusz Woźniak, Małgorzata Drąg-Zalesińska & Agnieszka Piwowar. (2019) Effect of estrogens and their metabolites genotoxicity on the pathogenesis and progression of estrogen-dependent breast cancer. Postępy Higieny i Medycyny Doświadczalnej 73, pages 909-919.
Crossref
Filomena Mottola, Concetta Iovine, Marianna Santonastaso, Maria Luisa Romeo, Severina Pacifico, Luigi Cobellis & Lucia Rocco. (2019) NPs-TiO2 and Lincomycin Coexposure Induces DNA Damage in Cultured Human Amniotic Cells. Nanomaterials 9:11, pages 1511.
Crossref
Alba García-Rodríguez, Laura Rubio, Laura Vila, Noel Xamena, Antonia Velázquez, Ricard Marcos & Alba Hernández. (2019) The Comet Assay as a Tool to Detect the Genotoxic Potential of Nanomaterials. Nanomaterials 9:10, pages 1385.
Crossref
Prashant Sharma, Na-Yoon Jang, Jae-Won Lee, Bum Chul Park, Young Keun Kim & Nam-Hyuk Cho. (2019) Application of ZnO-Based Nanocomposites for Vaccines and Cancer Immunotherapy. Pharmaceutics 11:10, pages 493.
Crossref
Julya Emmanuela de Andrade Vieira, Raíssa de Oliveira Ferreira, Douglas Marcel dos Reis Sampaio, Amanda Pereira da Costa Araújo & Guilherme Malafaia. (2019) An insight on the mutagenicity and cytotoxicity of zinc oxide nanoparticles in Gallus gallus domesticus (Phasianidae). Chemosphere 231, pages 10-19.
Crossref
Marina Senchukova. (2019) A Brief Review about the Role of Nanomaterials, Mineral-Organic Nanoparticles, and Extra-Bone Calcification in Promoting Carcinogenesis and Tumor Progression. Biomedicines 7:3, pages 65.
Crossref
Jingcao Shen, Dan Yang, Xingfan Zhou, Yuqian Wang, Shichuan Tang, Hong Yin, Jinglei Wang, Rui Chen & Jiaxiang Chen. (2019) Role of Autophagy in Zinc Oxide Nanoparticles-Induced Apoptosis of Mouse LEYDIG Cells. International Journal of Molecular Sciences 20:16, pages 4042.
Crossref
Liying Dong, Shutao WANG, Lin Zhang, Dongmei Liu & Hong You. (2022) Dbdpe and Zno Nps Synergistically Induce Neurotoxicity of  Sk-N-Sh Cells and Activate Mitochondrial Apoptosis Signaling Pathway and Nrf2-Mediated Antioxidant Pathway. SSRN Electronic Journal.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.