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Research Paper

Low miR-145 silenced by DNA methylation promotes NSCLC cell proliferation, migration and invasion by targeting mucin 1

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Pages 1071-1079 | Received 26 Jan 2015, Accepted 23 Apr 2015, Published online: 15 Jun 2015

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Song Zhang, Zhujun Cheng, Yanan Wang & Tianyu Han. (2021) The Risks of miRNA Therapeutics: In a Drug Target Perspective. Drug Design, Development and Therapy 15, pages 721-733.
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Articles from other publishers (17)

Justyna Raczkowska, Agnieszka Bielska, Adam Krętowski & Magdalena Niemira. (2023) Extracellular circulating miRNAs as potential non-invasive biomarkers in non-small cell lung cancer patients. Frontiers in Oncology 13.
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Hang Li, Shuya Zhao, Xin Chen, Guoxing Feng, Zhiyuan Chen & Saijun Fan. (2022) MiR-145 modulates the radiosensitivity of non-small cell lung cancer cells by suppression of TMOD3. Carcinogenesis 43:3, pages 288-296.
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Luděk Záveský, Eva Jandáková, Vít Weinberger, Veronika Hanzíková, Ondřej Slanař & Milada Kohoutová. (2022) Ascites in ovarian cancer: MicroRNA deregulations and their potential roles in ovarian carcinogenesis. Cancer Biomarkers 33:1, pages 1-16.
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Sarayut Geater, Pichitpon Chaniad, Keson Trakunran, Warangkana Keeratichananont, Suhaimee Buya, Paramee Thongsuksai & Pritsana Raungrut. (2021) Diagnostic and prognostic value of serum miR‑145 and vascular endothelial growth factor in non‑small cell lung cancer. Oncology Letters 23:1.
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Liangliang Xu, Yanfang Zhang, Jianwei Tang, Peng Wang, Lian Li, Xiaokai Yan, Xiaobo Zheng, Shengsheng Ren, Ming Zhang & Mingqing Xu. (2019) The Prognostic Value and Regulatory Mechanisms of microRNA-145 in Various Tumors: A Systematic Review and Meta-analysis of 50 Studies. Cancer Epidemiology, Biomarkers & Prevention 28:5, pages 867-881.
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Qun Liu, Jianhui Chen, Baolan Wang, Yulong Zheng, Yufeng Wan, Yi Wang, Liyang Zhou, Shu Liu, Gang Li & Yi Yan. (2018) Retracted : miR‐145 modulates epithelial‐mesenchymal transition and invasion by targeting ZEB2 in non–small cell lung cancer cell lines . Journal of Cellular Biochemistry 120:5, pages 8409-8418.
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Yong Cui, Guanlong Li, Xin Zhang, Fangfang Dai & Rongxiang Zhang. (2018) Increased MALAT1 expression contributes to cisplatin resistance in non‑small cell lung cancer. Oncology Letters.
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Alice Ramassone, Sara Pagotto, Angelo Veronese & Rosa Visone. (2018) Epigenetics and MicroRNAs in Cancer. International Journal of Molecular Sciences 19:2, pages 459.
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Gui‐Min Chen, A‐Juan Zheng, Jing Cai, Ping Han, Hong‐Bo Ji & Le‐Le Wang. (2017) Retracted: microRNA‐145‐3p inhibits non‐small cell lung cancer cell migration and invasion by targeting PDK1 via the mTOR signaling pathway . Journal of Cellular Biochemistry 119:1, pages 885-895.
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Yongmei Chang, Wensen Yan, Cong Sun, Qingfeng Liu, Jun Wang & Mingzhi Wang. (2017) miR‑145‑5p inhibits epithelial‑mesenchymal transition via the JNK signaling pathway by targeting MAP3K1 in non‑small cell lung cancer cells. Oncology Letters.
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Chiara De Santi, Ombretta Melaiu, Alessandra Bonotti, Luciano Cascione, Gianpiero Di Leva, Rudy Foddis, Alfonso Cristaudo, Marco Lucchi, Marco Mora, Anna Truini, Andrea Tironi, Bruno Murer, Renzo Boldorini, Monica Cipollini, Federica Gemignani, Pierluigi Gasparini, Luciano Mutti & Stefano Landi. (2017) Deregulation of miRNAs in malignant pleural mesothelioma is associated with prognosis and suggests an alteration of cell metabolism. Scientific Reports 7:1.
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Menglin Xu, Diane C. Wang, Xiangdong Wang & Yong Zhang. (2017) Correlation between mucin biology and tumor heterogeneity in lung cancer. Seminars in Cell & Developmental Biology 64, pages 73-78.
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Ting-qing Gan, Zu-cheng Xie, Rui-xue Tang, Tong-tong Zhang, Dong-yao Li, Zu-yun Li & Gang Chen. (2017) Clinical value of miR-145-5p in NSCLC and potential molecular mechanism exploration: A retrospective study based on GEO, qRT-PCR, and TCGA data. Tumor Biology 39:3, pages 101042831769168.
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Jichao Liu, Yongshuang Li, Ying Zou, Jiakui Zhang, Jiaxiang An, Jiao Guo, Minghui Ma & Dongqiu Dai. (2017) MicroRNA-497 acts as a tumor suppressor in gastric cancer and is downregulated by DNA methylation. Oncology Reports 38:1, pages 497-505.
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Zuzana Pastorkova, Jozef Skarda & Jozef Andel. (2016) The role of microRNA in metastatic processes of non-small cell lung carcinoma. Biomedical Papers 160:3, pages 343-357.
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Jingjing Du, Xiao Cheng, Linyuan Shen, Zhendong Tan, Jia Luo, Xiaoqian Wu, Chendong Liu, Qiong Yang, Yanzhi Jiang, Guoqing Tang, Xuewei Li, Shunhua Zhang & Li Zhu. (2016) Methylation of miR-145a-5p promoter mediates adipocytes differentiation. Biochemical and Biophysical Research Communications 475:1, pages 140-148.
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Yingying Zhang, Xucheng Yang, Haijun Wu, Weibin Zhou & Zhenzhen Liu. (2015) MicroRNA-145 inhibits migration and invasion via inhibition of fascin�1 protein expression in non-small-cell lung cancer cells. Molecular Medicine Reports.
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