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Cancer Biology & Therapy Volume 17, 2016 - Issue 5
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Research Paper

Anti-myeloma effect of pharmacological inhibition of Notch/gamma-secretase with RO4929097 is mediated by modulation of tumor microenvironment

Alexandra PisklakovaH. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA
,
Eileen GrigsonH. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA;The Wistar Institute, Philadelphia, PA, USA
,
Maria OzerovaH. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA
,
Feng ChenH. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA
,
Daniel M. SullivanH. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA
&
Yulia NefedovaH. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA;The Wistar Institute, Philadelphia, PA, USACorrespondence[email protected]
Pages 477-485 | Received 07 Oct 2015, Accepted 14 Feb 2016, Published online: 11 Apr 2016

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Maaike VJ Braham, Anil K Deshantri, Monique C Minnema, F Cumhur Öner, Raymond M Schiffelers, Marcel HAM Fens & Jacqueline Alblas. (2018) Liposomal drug delivery in an in vitro 3D bone marrow model for multiple myeloma. International Journal of Nanomedicine 13, pages 8105-8118.
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Articles from other publishers (6)

Hailin Chen, Tengteng Yu, Liang Lin, Lijie Xing, Shih-Feng Cho, Kenneth Wen, Kimberly Aardalen, Adwait Oka, Joni Lam, Mike Daley, Haihui Lu, Nikhil Munshi, Kenneth C. Anderson & Yu-Tzu Tai. (2022) γ-secretase inhibitors augment efficacy of BCMA-targeting bispecific antibodies against multiple myeloma cells without impairing T-cell activation and differentiation. Blood Cancer Journal 12:8.
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Yuh-Ching Gau, Tsung-Jang Yeh, Chin-Mu Hsu, Samuel Yien Hsiao & Hui-Hua Hsiao. (2022) Pathogenesis and Treatment of Myeloma-Related Bone Disease. International Journal of Molecular Sciences 23:6, pages 3112.
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Lavinia Raimondi, Angela De Luca, Gianluca Giavaresi, Stefania Raimondo, Alessia Gallo, Elisa Taiana, Riccardo Alessandro, Marco Rossi, Antonino Neri, Giuseppe Viglietto & Nicola Amodio. (2020) Non-Coding RNAs in Multiple Myeloma Bone Disease Pathophysiology. Non-Coding RNA 6:3, pages 37.
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Margot J. Pont, Tyler Hill, Gabriel O. Cole, Joe J. AbbottJessica KelliherAlexander I. Salter, Michael Hudecek, Melissa L. ComstockAnusha Rajan, Bharvin K. R. Patel, Jenna M. VoutsinasQian WuLingfeng Liu, Andrew J. CowanBrent L. WoodDamian J. Green & Stanley R. Riddell. (2019) γ-Secretase inhibition increases efficacy of BCMA-specific chimeric antigen receptor T cells in multiple myeloma. Blood 134:19, pages 1585-1597.
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Fengling Wang, Jinhui Wang, Zhaozhong Chong & Yanling Mu. (2019) A modified DAW-22 compound F-B1 inhibits Bcr/Abl and induces apoptosis in chronic myelogenous leukemia cells. Anti-Cancer Drugs 30:2, pages 159-166.
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Eva Skarmoutsou, Valentina Bevelacqua, Fabio D' Amico, Angela Russo, Demetrios�� Spandidos, Aurora Scalisi, Grazia Malaponte & Claudio Guarneri. (2018) FOXP3 expression is modulated by TGF‑β1/NOTCH1 pathway in human melanoma. International Journal of Molecular Medicine.
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