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Research Paper

A specific aptamer-cell penetrating peptides complex delivered siRNA efficiently and suppressed prostate tumor growth in vivo

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Pages 498-506 | Received 09 Dec 2015, Accepted 14 Feb 2016, Published online: 13 Apr 2016

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Lei Lyu, Lu-qi Huang, Tao Huang, Wei Xiang, Jing-dong Yuan & Chuan-hua Zhang. (2018) Cell-penetrating peptide conjugates of gambogic acid enhance the antitumor effect on human bladder cancer EJ cells through ROS-mediated apoptosis. Drug Design, Development and Therapy 12, pages 743-756.
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Yadollah Omidi, Jaleh Barar, Somayeh Vandghanooni, Morteza Eskandani & Hossein Omidian. 2023. Aptamers Engineered Nanocarriers for Cancer Therapy. Aptamers Engineered Nanocarriers for Cancer Therapy 103 139 .
Carlos David Cruz-Hernández, Griselda Rodríguez-Martínez, Sergio A. Cortés-Ramírez, Miguel Morales-Pacheco, Marian Cruz-Burgos, Alberto Losada-García, Juan Pablo Reyes-Grajeda, Imelda González-Ramírez, Vanessa González-Covarrubias, Ignacio Camacho-Arroyo, Marco Cerbón & Mauricio Rodríguez-Dorantes. (2022) Aptamers as Theragnostic Tools in Prostate Cancer. Biomolecules 12:8, pages 1056.
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Nuno Vale, Diana Duarte, Sara Silva, Ana Salomé Correia, Bárbara Costa, Maria João Gouveia & Abigail Ferreira. (2020) Cell-penetrating peptides in oncologic pharmacotherapy: A review. Pharmacological Research 162, pages 105231.
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Sol Min, Kichul Kim, Seockmo Ku, Jeong‐Yoon Park, Jeongmin Seo & Sangho Roh. (2020) Newly synthesized peptide, Ara‐27, exhibits significant improvement in cell‐penetrating ability compared to conventional peptides. Biotechnology Progress 36:5.
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Milad Ashrafizadeh, Kiavash Hushmandi, Ebrahim Rahmani Moghadam, Vahideh Zarrin, Sharareh Hosseinzadeh Kashani, Saied Bokaie, Masoud Najafi, Shima Tavakol, Reza Mohammadinejad, Noushin Nabavi, Chia-Ling Hsieh, Atefeh Zarepour, Ehsan Nazarzadeh Zare, Ali Zarrabi & Pooyan Makvandi. (2020) Progress in Delivery of siRNA-Based Therapeutics Employing Nano-Vehicles for Treatment of Prostate Cancer. Bioengineering 7:3, pages 91.
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Krishna Baxi, Sujata Sawarkar, Munira Momin, Vainav Patel & Trinette Fernandes. (2020) Vaginal siRNA delivery: overview on novel delivery approaches. Drug Delivery and Translational Research 10:4, pages 962-974.
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Zhaoying Fu & Jim Xiang. (2020) Aptamers, the Nucleic Acid Antibodies, in Cancer Therapy. International Journal of Molecular Sciences 21:8, pages 2793.
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Jaehoon Lee, Mijin Kwon, Naeun Oh, Jaehyun Park, Sangkyu Park, Jeongmin Seo & Sangho Roh. (2020) Cell-Penetrating Peptides Enhance the Activity of Human Fibroblast Growth Factor 2 by Prolonging the Retention Time: A New Vision for Drug-Delivery Systems. International Journal of Molecular Sciences 21:2, pages 442.
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Ana Paula Dinis Ano Bom, Patrícia Cristina da Costa Neves, Carlos Eduardo Bonacossa de Almeida, Dilson Silva & Sotiris Missailidis. (2019) Aptamers as Delivery Agents of siRNA and Chimeric Formulations for the Treatment of Cancer. Pharmaceutics 11:12, pages 684.
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Weibin Li, Meng Zhao, Huihui Yan, Kaiyu Wang & XIaopeng lan. (2019) Aptamer Oligonucleotides as Potential Therapeutics in Hematologic Diseases. Mini-Reviews in Medicinal Chemistry 19:10, pages 788-795.
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Padmanaban Sivakumar, Sumin Kim, Han Chang Kang & Min Suk Shim. (2018) Targeted siRNA delivery using aptamer‐siRNA chimeras and aptamer‐conjugated nanoparticles. WIREs Nanomedicine and Nanobiotechnology 11:3.
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Fatemeh Araste, Khalil Abnous, Maryam Hashemi, Seyed Mohammad Taghdisi, Mohammad Ramezani & Mona Alibolandi. (2018) Peptide-based targeted therapeutics: Focus on cancer treatment. Journal of Controlled Release 292, pages 141-162.
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Somayeh Vandghanooni, Morteza Eskandani, Jaleh Barar & Yadollah Omidi. (2018) Bispecific therapeutic aptamers for targeted therapy of cancer: a review on cellular perspective. Journal of Molecular Medicine 96:9, pages 885-902.
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Zimu Zhang, Zhi Yao & Rongxin Zhang. 2018. The Epigenetics of Autoimmunity. The Epigenetics of Autoimmunity 359 386 .
Ahad Mokhtarzadeh, Maryam Tabarzad, Javad Ranjbari, Miguel de la Guardia, Maryam Hejazi & Mohammad Ramezani. (2016) Aptamers as smart ligands for nano-carriers targeting. TrAC Trends in Analytical Chemistry 82, pages 316-327.
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Subash C. B. Gopinath, Thangavel Lakshmipriya, Yeng Chen, M. K. Md Arshad, Jesinda P. Kerishnan, A. R. Ruslinda, Yarub Al-Douri, C. H. Voon & Uda Hashim. (2016) Cell-targeting aptamers act as intracellular delivery vehicles. Applied Microbiology and Biotechnology 100:16, pages 6955-6969.
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Shanni Hong, Na Sun, Min Liu, Jine Wang & Renjun Pei. (2016) Building a chimera of aptamer–antisense oligonucleotide for silencing galectin-1 gene. RSC Advances 6:113, pages 112445-112450.
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