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The emerging role of lysine demethylases in DNA damage response: dissecting the recruitment mode of KDM4D/JMJD2D to DNA damage sites

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Pages 950-958 | Received 03 Dec 2014, Accepted 27 Jan 2015, Published online: 01 Apr 2015

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Samah W. Awwad, Malak M. Darawshe, Feras E. Machour, Inbar Arman & Nabieh Ayoub. (2023) Recruitment of RBM6 to DNA Double-Strand Breaks Fosters Homologous Recombination Repair. Molecular and Cellular Biology 43:3, pages 130-142.
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Michal Goldberg. (2015) KDM4D crosstalks with PARP1 and RNA at DNA DSBs . Cell Cycle 14:10, pages 1495-1495.
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Wenjian Yao, Jianjun Wang, Li Zhu, Xiangbo Jia, Lei Xu, Xia Tian, Shuai Hu, Sen Wu & Li Wei. (2021) Epigenetic Regulator KDM4D Restricts Tumorigenesis via Modulating SYVN1/HMGB1 Ubiquitination Axis in Esophageal Squamous Cell Carcinoma. Frontiers in Oncology 11.
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May Levin, Michal Stark & Yehuda G. Assaraf. (2018) The JmjN domain as a dimerization interface and a targeted inhibitor of KDM4 demethylase activity. Oncotarget 9:24, pages 16861-16882.
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Zhen Fang, Tian-qi Wang, Hui Li, Guo Zhang, Xiao-ai Wu, Li Yang, Yu-lan Peng, Jun Zou, Lin-li Li, Rong Xiang & Sheng-yong Yang. (2017) Discovery of pyrazolo[1,5-a]pyrimidine-3-carbonitrile derivatives as a new class of histone lysine demethylase 4D (KDM4D) inhibitors. Bioorganic & Medicinal Chemistry Letters 27:14, pages 3201-3204.
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Samah W Awwad, Enas R Abu‐Zhayia, Noga Guttmann‐Raviv & Nabieh Ayoub. (2017) NELF ‐E is recruited to DNA double‐strand break sites to promote transcriptional repression and repair . EMBO reports 18:5, pages 745-764.
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