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Direct interactions with both p27 and Cdk2 regulate Spy1-mediated proliferation in vivo and in vitro

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Pages 128-136 | Received 02 Sep 2015, Accepted 12 Nov 2015, Published online: 15 Jan 2016

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Matthew R. Dewhurst & Philipp Kaldis. (2016) The Speedy A, Cdk2, p27 triangle. Cell Cycle 15:4, pages 489-490.
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Marina Bury, Benjamin Le Calvé, Gerardo Ferbeyre, Volker Blank & Frédéric Lessard. (2021) New Insights into CDK Regulators: Novel Opportunities for Cancer Therapy. Trends in Cell Biology 31:5, pages 331-344.
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Laura Gonzalez & Angel R. Nebreda. (2020) RINGO/Speedy proteins, a family of non-canonical activators of CDK1 and CDK2. Seminars in Cell & Developmental Biology 107, pages 21-27.
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Sunho Lee, Sueon Kim, Hyunwoo Chung, Ji Hwan Moon, Seong Jun Kang & Chung-Gyu Park. (2020) Mesenchymal stem cell-derived exosomes suppress proliferation of T cells by inducing cell cycle arrest through p27kip1/Cdk2 signaling. Immunology Letters 225, pages 16-22.
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Niannian Li, Gang Meng, Xiaoling Tong, Fuze Sun, Jie Zeng, Yanmin Bai, Shubo Liang, Hai Hu, Lanlan Liu, Minjin Han, Cheng Lu & Fangyin Dai. (2019) Effects of P27/Bmdacapo, in the CIP/KIP family, on cell proliferation, growth and development in the silkworm (Bombyx mori). Gene 700, pages 31-37.
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Xu-Dong Wang, Min-Wei Zhu, Dan Shan, Shu-Yu Wang, Xiang Yin, Yue-Qing Yang, Tian-Hang Wang, Chun-Ting Zhang, Ying Wang, Wei-Wei Liang, Jun Zhang, Hai-Zhi Jiang, Guang-Tao Dong, Hong-Quan Jiang, Yan Qi & Hong-Lin Feng. (2019) Spy1, a unique cell cycle regulator, alters viability in ALS motor neurons and cell lines in response to mutant SOD1-induced DNA damage. DNA Repair 74, pages 51-62.
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HongMei Wang, WenFei Dong & Liang Wang. (2019) Expression profile and potential functional differentiation of the Speedy/RINGO family in mice. Gene 683, pages 80-86.
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Denise A McGrath, Bre‐Anne Fifield, Aimee H Marceau, Sarvind Tripathi, Lisa A Porter & Seth M Rubin. (2017) Structural basis of divergent cyclin‐dependent kinase activation by Spy1/ RINGO proteins . The EMBO Journal 36:15, pages 2251-2262.
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Rosa-Maria Ferraiuolo, Janice Tubman, Indrajit Sinha, Caroline Hamm & Lisa Ann Porter. (2017) The cyclin-like protein, SPY1, regulates the ERα and ERK1/2 pathways promoting tamoxifen resistance. Oncotarget 8:14, pages 23337-23352.
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Baoying Hu, Lu Hua, Wenkai Ni, Miaomiao Wu, Daliang Yan, Yuyan Chen, Cuihua Lu, Buyou Chen & Chunhua Wan. (2017) Nucleostemin/GNL3 promotes nucleolar polyubiquitylation of p27kip1 to drive hepatocellular carcinoma progression. Cancer Letters 388, pages 220-229.
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Zhaowei TuMustafa Bilal BayazitHongbin LiuJingjing ZhangKiran BusayavalasaSanjiv RisalJingchen ShaoAnde SatyanarayanaVincenzo CoppolaLino TessarolloMeenakshi SinghChunwei ZhengChunsheng HanZijiang ChenPhilipp Kaldis, Jan-Åke Gustafsson & Kui Liu. (2016) Speedy A–Cdk2 binding mediates initial telomere–nuclear envelope attachment during meiotic prophase I independent of Cdk2 activation. Proceedings of the National Academy of Sciences 114:3, pages 592-597.
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