Citations (52)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (3)
Maowen Huang, Xiaohui Hua, Jiheng Xu, Zhongxian Tian, Jiajing Wang, Hengchao Chen, Xuyao Wang, Peng Shu, Hongyan Ye, Jianfeng Shu & Chuanshu Huang. (2022) Induction of p27 contributes to inhibitory effect of isorhapontigenin (ISO) on malignant transformation of human urothelial cells. Cell Cycle 0:0, pages 1-14.
Read now
Read now
Valentina Iadevaia, Maikel D. Wouters, Alexander Kanitz, Ana M. Matia-González, Emma E. Laing & André P. Gerber. (2020) Tandem RNA isolation reveals functional rearrangement of RNA-binding proteins on CDKN1B/p27Kip1 3’UTRs in cisplatin treated cells. RNA Biology 17:1, pages 33-46.
Read now
Read now
Karthik M. Kodigepalli, Serena Bonifati, Nagaraja Tirumuru & Li Wu. (2018) SAMHD1 modulates in vitro proliferation of acute myeloid leukemia-derived THP-1 cells through the PI3K-Akt-p27 axis. Cell Cycle 17:9, pages 1124-1137.
Read now
Read now
Articles from other publishers (49)
Elizabeth A. Barnes, Reiji Ito, Xibing Che, Cristina M. Alvira & David N. Cornfield. (2023) Loss of prolyl hydroxylase 1 and 2 in SM22α-expressing cells prevents Hypoxia-Induced pulmonary hypertension. American Journal of Physiology-Lung Cellular and Molecular Physiology 325:6, pages L741-L755.
Crossref
Crossref
Esra Katkat, Yeliz Demirci, Guillaume Heger, Doga Karagulle, Irene Papatheodorou, Alvis Brazma & Gunes Ozhan. (2023) Canonical Wnt and TGF-β/BMP signaling enhance melanocyte regeneration but suppress invasiveness, migration, and proliferation of melanoma cells. Frontiers in Cell and Developmental Biology 11.
Crossref
Crossref
Rana Aldabbas, Olfat G. Shaker, Manal F. Ismail & Nevine Fathy. (2022) miRNA-559 and MTDH as possible diagnostic markers of psoriasis: Role of PTEN/AKT/FOXO pathway in disease pathogenesis. Molecular and Cellular Biochemistry 478:7, pages 1427-1438.
Crossref
Crossref
Abul H. Elahi, Cordelia S. Morales, Xiaoliang L. Xu, Alexia Eliades, Philippos C. Patsalis, David H. Abramson & Suresh C. Jhanwar. (2023) Targeted pharmacologic inhibition of S-phase kinase-associated protein 2 (SKP2) mediated cell cycle regulation in lung and other RB-Related cancers: A brief review of current status and future prospects. Advances in Biological Regulation 88, pages 100964.
Crossref
Crossref
Theodore Leng, Georgia Kamboj, Xiaoyun Sun, Heather Chang, Prisha Davda, Majesty Greer & Creed M. Stary. (2023) MicroRNA-494 augments fibrotic transformation of human retinal pigment epithelial cells and targets p27 with cell-type specificity. Frontiers in Ophthalmology 3.
Crossref
Crossref
Madara Dzudzilo, Ingrīda Čēma, Regīna Kleina, Šimons Svirskis & Guntars Selga. (2022) Characteristics of the dual nature of the p27 protein in oral leukoplakias and cancer. Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences. 76:5-6, pages 665-673.
Crossref
Crossref
Jolien Beeken, Sofie Kessels, Jean-Michel Rigo, Yeranddy A. Alpizar, Laurent Nguyen & Bert Brône. (2022) p27kip1 Modulates the Morphology and Phagocytic Activity of Microglia. International Journal of Molecular Sciences 23:18, pages 10432.
Crossref
Crossref
Heidelinde Jäkel, Martin Taschler, Karin Jung, Christina Weinl, Fragka Pegka, Michael Keith Kullmann, Silvio Roland Podmirseg, Sayantanee Dutta, Markus Moser & Ludger Hengst. (2022) Inability to phosphorylate Y88 of p27Kip1 enforces reduced p27 protein levels and accelerates leukemia progression. Leukemia 36:7, pages 1916-1925.
Crossref
Crossref
Ryan McGowan, Áine Sally, Anthony McCabe, Brian Michael Moran & Karen Finn. (2022) Circulating Nucleic Acids as Novel Biomarkers for Pancreatic Ductal Adenocarcinoma. Cancers 14:8, pages 2027.
Crossref
Crossref
Zohaib Rana, Rhonda J Rosengren & Paul F Smith. (2022) Exploring the Mechanism and Suggesting Combination Therapies for HDAC Inhibitors in Androgen Receptor-Null Prostate Cancer Using Multivariate Statistical Analysis and Data Mining Techniques. Bioinformatics and Biology Insights 16, pages 117793222211454.
Crossref
Crossref
Dorothy Hung, Douglas Lenton, Renee Eslick, Richard Blennerhassett, Maansi Joshi, Georgia McCaughan, Samantha Day & Dale Wright. (2021) Chromosome microarray characterisation of chromosome arm 12p loss associated with complex molecular karyotype and recurrent adverse cytogenetic markers in multiple myeloma. Genes, Chromosomes and Cancer 60:10, pages 668-677.
Crossref
Crossref
Mengjie Guo, Pinggang Ding, Zhen Zhu, Lu Fan, Yanyan Zhou, Shu Yang, Ye Yang & Chunyan Gu. (2021) Targeting RFWD2 as an Effective Strategy to Inhibit Cellular Proliferation and Overcome Drug Resistance to Proteasome Inhibitor in Multiple Myeloma. Frontiers in Cell and Developmental Biology 9.
Crossref
Crossref
Juan Tan, Zhaoxia Zhong, Wen Xu & Naiyi Zhang. (2021) Overexpressed Hsa_circ_0001326 Contributes to the Decreased Cell Viability in SWAN71 Cells by Regulating MiR-186-5p/p27 Kip1 Axis. Biological and Pharmaceutical Bulletin 44:4, pages 507-514.
Crossref
Crossref
Debora Bencivenga, Emanuela Stampone, Arianna Aulitto, Annunziata Tramontano, Clementina Barone, Aide Negri, Domenico Roberti, Silverio Perrotta, Fulvio Della Ragione & Adriana Borriello. (2021)
A cancer‐associated
CDKN1B
mutation induces p27 phosphorylation on a novel residue: a new mechanism for tumor suppressor loss‐of‐function
. Molecular Oncology 15:4, pages 915-941.
Crossref
Crossref
Veronica Moncho-AmorProbir ChakravartyChristophe Galichet, Ander Matheu, Robin Lovell-Badge & Karine Rizzoti. (2021)
SOX2 is required independently in both stem and differentiated cells for pituitary tumorigenesis in
p27
-null mice
. Proceedings of the National Academy of Sciences 118:7.
Crossref
Crossref
Woosuk Kim, Hyun Jung Kwon, Hyo Young Jung, Kyu Ri Hahn, Yeo Sung Yoon, In Koo Hwang, Soo Young Choi & Dae Won Kim. (2020) P27 Protects Neurons from Ischemic Damage by Suppressing Oxidative Stress and Increasing Autophagy in the Hippocampus. International Journal of Molecular Sciences 21:24, pages 9496.
Crossref
Crossref
Huanhuan Ji, Guoxiang Liu, Jingjing Han, Feng Zhu, Xiaolei Dong & Bing Li. (2020) C-phycocyanin inhibits epithelial-to-mesenchymal transition in Caski cells. Cancer Cell International 20:1.
Crossref
Crossref
Kul Raj Rai, Biao Chen, Zhonghui Zhao, Yuhai Chen, Jiayue Hu, Shasha Liu, Mohamed Maarouf, Yingying Li, Meng Xiao, Yuan Liao & Ji‐Long Chen. (2020)
Robust expression of
p27Kip1
induced by viral infection is critical for antiviral innate immunity
. Cellular Microbiology 22:11.
Crossref
Crossref
Gian Luigi Russo, Emanuela Stampone, Carmen Cervellera & Adriana Borriello. (2020) Regulation of p27Kip1 and p57Kip2 Functions by Natural Polyphenols. Biomolecules 10:9, pages 1316.
Crossref
Crossref
Ada Nowosad, Pauline Jeannot, Caroline Callot, Justine Creff, Renaud Thierry Perchey, Carine Joffre, Patrice Codogno, Stephane Manenti & Arnaud Besson. (2020) p27 controls Ragulator and mTOR activity in amino acid-deprived cells to regulate the autophagy–lysosomal pathway and coordinate cell cycle and cell growth. Nature Cell Biology 22:9, pages 1076-1090.
Crossref
Crossref
Kaicheng Yang, Yanping Chen, Zifeng Cui, He Chen, Lei Yang, Jianguang Zhao, Fengyu Luo, Shasha Man, Jianghui Zhao & Lingyu Jin. (2020) MicroRNA‐222‐3p participates in the development of oral squamous cell carcinoma by targeting CDKN1B. Journal of Oral Pathology & Medicine 49:7, pages 621-629.
Crossref
Crossref
Hiroki Yukimoto, Tatsuo Miyamoto, Tohru Kiyono, Shujie Wang, Shinya Matsuura, Akira Mizoguchi, Naoyuki Katayama, Masaki Inagaki & Kousuke Kasahara. (2020) A novel CDK-independent function of p27Kip1 in preciliary vesicle trafficking during ciliogenesis. Biochemical and Biophysical Research Communications 527:3, pages 716-722.
Crossref
Crossref
Yongxiang Luo, Zhaoyin Fu, Peisheng Wu, Dawu Zheng & Xiumei Zhang. (2020) The clinicopathological and prognostic significance of P27kip in hepatocellular carcinoma patients: A systemic review and meta-analysis. Gene 734, pages 144351.
Crossref
Crossref
P. Henri, C. Prevel, M. Pellerano, J. Lacotte, P.E. Stoebner, M.C. Morris & L. Meunier. (2019)
Psoriatic epidermis is associated with upregulation of
CDK
2 and inhibition of
CDK
4 activity
. British Journal of Dermatology 182:3, pages 678-689.
Crossref
Crossref
Gian Luca Rampioni Vinciguerra, Francesca Citron, Ilenia Segatto, Barbara Belletti, Andrea Vecchione & Gustavo Baldassarre. (2019) p27kip1 at the crossroad between actin and microtubule dynamics. Cell Division 14:1.
Crossref
Crossref
Giovanna Carrà, Isabella Russo, Angelo Guerrasio & Alessandro Morotti. (2019) Nuclear-cytoplasmic Shuttling in Chronic Myeloid Leukemia: Implications in Leukemia Maintenance and Therapy. Cells 8:10, pages 1248.
Crossref
Crossref
Guoqing Yin, Bo Zhang & Jia Li. (2019) miR‑221‑3p promotes the cell growth of non‑small cell lung cancer by targeting p27. Molecular Medicine Reports.
Crossref
Crossref
Xiaoting Jia, Lejuan Shi, Xiaorong Wang, Liyun Luo, Li Ling, Jiang Yin, Ying Song, Zhijie Zhang, Ni Qiu, Hao Liu, Min Deng, Zhimin He, Hongsheng Li & Guopei Zheng. (2019) KLF5 regulated lncRNA RP1 promotes the growth and metastasis of breast cancer via repressing p27kip1 translation. Cell Death & Disease 10:5.
Crossref
Crossref
Silvio R Podmirseg, Jonathan Vosper & Ludger Hengst. (2019)
p27
Kip1
– p(RhoB)lematic in lung cancer
. The Journal of Pathology 248:1, pages 3-5.
Crossref
Crossref
Arthur W. Currier, E. A. Kolb, Richard G. Gorlick, Michael E. Roth, Vidya Gopalakrishnan & Valerie B. Sampson. (2019) p27/Kip1 functions as a tumor suppressor and oncoprotein in osteosarcoma. Scientific Reports 9:1.
Crossref
Crossref
Lina Ding, Lauren B. Shunkwiler, Nicholas W. Harper, Yang Zhao, Kunihiko Hinohara, Sung Jin Huh, Muhammad B. Ekram, Jan Guz, Michael J. Kern, Alexander Awgulewitsch, James D. Shull, Bart M. G. Smits & Kornelia Polyak. (2019) Deletion of Cdkn1b in ACI rats leads to increased proliferation and pregnancy-associated changes in the mammary gland due to perturbed systemic endocrine environment. PLOS Genetics 15:3, pages e1008002.
Crossref
Crossref
Mariagrazia Granata, Evangelia Skarmoutsou, Pietro Gangemi, Maria C. Mazzarino & Fabio D’Amico. (2018)
S100A7, Jab1, and p27
kip1
expression in psoriasis and S100A7 CRISPR‐activated human keratinocyte cell line
. Journal of Cellular Biochemistry 120:3, pages 3384-3392.
Crossref
Crossref
Olivier Calvayrac, Ada Nowosad, Stéphanie Cabantous, Lin‐Po Lin, Sarah Figarol, Pauline Jeannot, Murielle P Serres, Caroline Callot, Renaud T Perchey, Justine Creff, Estelle Taranchon‐Clermont, Isabelle Rouquette, Gilles Favre, Anne Pradines, Stephane Manenti, Julien Mazieres, Huei Lee & Arnaud Besson. (2018)
Cytoplasmic p27
Kip1
promotes tumorigenesis via suppression of RhoB activity
. The Journal of Pathology.
Crossref
Crossref
Yifeng Yuan, Jing Yang, Wenxiong Zhu, Tao liu, JuQiao He, Qing Zhou, Xing Zhou & Xi Zhang. (2018) Qianlongtong Inhibits Proliferation and Induces Apoptosis of Hyperplastic Prostate Cells. American Journal of Men's Health 12:5, pages 1548-1553.
Crossref
Crossref
Arkadiusz Czerwonka, Marta K. Lemieszek, Monika Karpińska, Joanna Matysiak, Andrzej Niewiadomy & Wojciech Rzeski. (2018) Evaluation of the effect of 2-(2,4-dihydroxyphenyl)-4H-benzofuro[3,2-d][1,3]thiazin-4-one on colon cells and its anticancer potential. Medicinal Chemistry Research 27:9, pages 2150-2159.
Crossref
Crossref
Martina Cusan, Giorgia Mungo, Mara De Marco Zompit, Ilenia Segatto, Barbara Belletti & Gustavo Baldassarre. (2018) Landscape of CDKN1B Mutations in Luminal Breast Cancer and Other Hormone-Driven Human Tumors. Frontiers in Endocrinology 9.
Crossref
Crossref
Oriol Bachs, Edurne Gallastegui, Serena Orlando, Anna Bigas, José Manuel Morante-Redolat, Joan Serratosa, Isabel Fariñas, Rosa Aligué & Maria Jesús Pujol. (2018) Role of p27Kip1 as a transcriptional regulator. Oncotarget 9:40, pages 26259-26278.
Crossref
Crossref
Martina Roilo, Michael K Kullmann & Ludger Hengst. (2018) Cold-inducible RNA-binding protein (CIRP) induces translation of the cell-cycle inhibitor p27Kip1. Nucleic Acids Research 46:6, pages 3198-3210.
Crossref
Crossref
Guosong Jiang, Chao Huang, Jingxia Li, Haishan Huang, Jingjing Wang, Yawei Li, Fei Xie, Honglei Jin, Junlan Zhu & Chuanshu Huang. (2018) Transcriptional and post-transcriptional upregulation of p27 mediates growth inhibition of isorhapontigenin (ISO) on human bladder cancer cells. Carcinogenesis 39:3, pages 482-492.
Crossref
Crossref
Aaron H. Phillips, Li Ou, Alexandre Gay, Arnaud Besson & Richard W. Kriwacki. (2018) Mapping Interactions between p27 and RhoA that Stimulate Cell Migration. Journal of Molecular Biology 430:6, pages 751-758.
Crossref
Crossref
Pauline Jeannot & Arnaud Besson. (2017) Régulation des invadopodes : un nouveau rôle dans l’invasion cellulaire pour p27. médecine/sciences 33:12, pages 1023-1025.
Crossref
Crossref
Smitha Antony, Guojian Jiang, Yongzhong Wu, Jennifer L. Meitzler, Hala R. Makhlouf, Diana C. Haines, Donna Butcher, Dave S. Hoon, Jiuping Ji, Yiping Zhang, Agnes Juhasz, Jiamo Lu, Han Liu, Iris Dahan, Mariam Konate, Krishnendu K. Roy & James H. Doroshow. (2017)
NADPH oxidase 5 (NOX5)-induced reactive oxygen signaling modulates normoxic HIF-1α and p27
Kip1
expression in malignant melanoma and other human tumors
. Molecular Carcinogenesis 56:12, pages 2643-2662.
Crossref
Crossref
Mei-Ling Chan, Chia-Chun Yu, Jui-Ling Hsu, Wohn-Jenn Leu, She-Hung Chan, Lih-Ching Hsu, Shih-Ping Liu, Polina M. Ivantcova, Özdemir Dogan, Stefan Bräse, Konstantin V. Kudryavtsev & Jih-Hwa Guh. (2017) Enantiomerically pure β-dipeptide derivative induces anticancer activity against human hormone-refractory prostate cancer through both PI3K/Akt-dependent and -independent pathways. Oncotarget 8:57, pages 96668-96683.
Crossref
Crossref
Pietro Di Fazio, Moritz Maass, Silvia Roth, Christian Meyer, Joana Grups, Peter Rexin, Detlef K Bartsch & Andreas Kirschbaum. (2017) Expression of hsa-let-7b-5p, hsa-let-7f-5p, and hsa-miR-222-3p and their putative targets HMGA2 and CDKN1B in typical and atypical carcinoid tumors of the lung. Tumor Biology 39:10, pages 101042831772841.
Crossref
Crossref
Matteo Barberis & Paul Verbruggen. (2017) Quantitative Systems Biology to decipher design principles of a dynamic cell cycle network: the “Maximum Allowable mammalian Trade–Off–Weight” (MAmTOW). npj Systems Biology and Applications 3:1.
Crossref
Crossref
Yoh Dobashi, Hiroyoshi Tsubochi, Kentaro Minegishi, Masatoshi Kitagawa, Shinichi Otani & Akishi Ooi. (2017) Regulation of p27 by ubiquitin ligases and its pathological significance in human lung carcinomas. Human Pathology 66, pages 67-78.
Crossref
Crossref
Ross D. Merkin, Elizabeth A. Vanner, Jamie L. Romeiser, A. Laurie W. Shroyer, Luisa F. Escobar-Hoyos, Jinyu Li, Robert S. Powers, Stephanie Burke & Kenneth R. Shroyer. (2017) Keratin 17 is overexpressed and predicts poor survival in estrogen receptor–negative/human epidermal growth factor receptor-2–negative breast cancer. Human Pathology 62, pages 23-32.
Crossref
Crossref
Pauline Jeannot, Ada Nowosad, Renaud T Perchey, Caroline Callot, Evangeline Bennana, Takanori Katsube, Patrick Mayeux, François Guillonneau, Stéphane Manenti & Arnaud Besson. (2017) p27Kip1 promotes invadopodia turnover and invasion through the regulation of the PAK1/Cortactin pathway. eLife 6.
Crossref
Crossref
Ilenia Pellizzari, Linda Fabris, Stefania Berton, Ilenia Segatto, Francesca Citron, Sara D’Andrea, Martina Cusan, Sara Benevol, Tiziana Perin, Samuele Massarut, Vincenzo Canzonieri, Monica Schiappacassi, Barbara Belletti & Gustavo Baldassarre. (2016) p27kip1 expression limits H-Ras-driven transformation and tumorigenesis by both canonical and non-canonical mechanisms. Oncotarget 7:40, pages 64560-64574.
Crossref
Crossref