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Cell Cycle Volume 16, 2017 - Issue 10
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Susceptibility of ATM-deficient pancreatic cancer cells to radiation

Michael AyarsDepartment of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, USAORCID Iconhttp://orcid.org/0000-0002-1300-5383
ORCID Icon,
James EshlemanDepartment of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA;Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
&
Michael GogginsDepartment of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA;Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA;Department of Medicine, The Sol Goldman Pancreatic Cancer Research Centre; The Johns Hopkins University School of Medicine, Baltimore, MD, USACorrespondence[email protected]
Pages 991-998 | Received 15 Feb 2017, Accepted 22 Mar 2017, Published online: 28 Apr 2017

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Sreenivasa Chandana, Hani M. Babiker & Daruka Mahadevan. (2019) Therapeutic trends in pancreatic ductal adenocarcinoma (PDAC). Expert Opinion on Investigational Drugs 28:2, pages 161-177.
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Pranit Singh, Jacob Adams, Sylvia Choo, Matthew Adams, Jordan McDonald, Laura Barton, Richard Levine, Dae Won Kim, Russell Palm, Jessica Frakes & Sarah Hoffe. (2023) Locoregional Chemoradiation for a Patient with BRCA1 Stage IV Pancreatic Adenocarcinoma. Applied Radiation Oncology.
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Chirayu Mohindroo, Ana De Jesus-Acosta, Matthew B. Yurgelun, Anirban Maitra, Maureen Mork & Florencia McAllister. (2022) The Evolving Paradigm of Germline Testing in Pancreatic Ductal Adenocarcinoma and Implications for Clinical Practice. Surgical Pathology Clinics 15:3, pages 491-502.
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Yuewen Zhang, Lei Wu, Zhao Wang, Jinpeng Wang, Shrabasti Roychoudhury, Bartlomiej Tomasik, Gang Wu, Geng Wang, Xinrui Rao & Rui Zhou. (2022) Replication Stress: A Review of Novel Targets to Enhance Radiosensitivity-From Bench to Clinic. Frontiers in Oncology 12.
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Chloe Gulliver, Ralf Hoffmann & George S. Baillie. (2022) Ataxia-telangiectasia mutated and ataxia telangiectasia and Rad3-related kinases as therapeutic targets and stratification indicators for prostate cancer. The International Journal of Biochemistry & Cell Biology 147, pages 106230.
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Aditi Jain & Vikas Bhardwaj. (2021) Therapeutic resistance in pancreatic ductal adenocarcinoma: Current challenges and future opportunities. World Journal of Gastroenterology 27:39, pages 6527-6550.
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Bin Hu, Xiumei Ma, Renhua Huang, Zheng Wu, Jun Lu, Yuntao Guo, Jianmin Tang, Chunhui Ma, Jun Ma, Lei Zhang & Yongrui Bai. (2021) Identification of Key Genes Mutations Associated With the Radiosensitivity by Whole Exome Sequencing in Pancreatic Cancer. Frontiers in Oncology 11.
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Parnia Rahnamay Farnood, Romina Danesh Pazhooh, Zatollah Asemi & Bahman Yousefi. (2021) DNA damage response and repair in pancreatic cancer development and therapy. DNA Repair 103, pages 103116.
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Elizabeth D. Thompson, Nicholas J. Roberts, Laura D. Wood, James R. Eshleman, Michael G. Goggins, Scott E. Kern, Alison P. Klein & Ralph H. Hruban. (2020) The genetics of ductal adenocarcinoma of the pancreas in the year 2020: dramatic progress, but far to go. Modern Pathology 33:12, pages 2544-2563.
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Mariam Gachechiladze, Josef Skarda, Katerina Bouchalova, Alex Soltermann & Markus Joerger. (2020) Predictive and Prognostic Value of DNA Damage Response Associated Kinases in Solid Tumors. Frontiers in Oncology 10.
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Josephine Görte, Elke Beyreuther, Erik H. J. Danen & Nils Cordes. (2020) Comparative Proton and Photon Irradiation Combined with Pharmacological Inhibitors in 3D Pancreatic Cancer Cultures. Cancers 12:11, pages 3216.
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Charles R. Dunlop, Yann Wallez, Timothy Isaac Johnson, Sandra Bernaldo de Quirós Fernández, Stephen T. Durant, Elaine B. Cadogan, Alan Lau, Frances M. Richards & Duncan I. Jodrell. (2020) Complete loss of ATM function augments replication catastrophe induced by ATR inhibition and gemcitabine in pancreatic cancer models. British Journal of Cancer 123:9, pages 1424-1436.
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Neha Nanda & Nicholas J. Roberts. (2020) ATM Serine/Threonine Kinase and its Role in Pancreatic Risk. Genes 11:1, pages 108.
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Danielle Hutchings, Zhengdong Jiang, Michael Skaro, Matthew J. Weiss, Christopher L. Wolfgang, Martin A. Makary, Jin He, John L. Cameron, Lei Zheng, David S. Klimstra, Randall E. Brand, Aatur D. Singhi, Michael Goggins, Alison P. Klein, Nicholas J. Roberts & Ralph H. Hruban. (2019) Histomorphology of pancreatic cancer in patients with inherited ATM serine/threonine kinase pathogenic variants. Modern Pathology 32:12, pages 1806-1813.
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Samantha A. Armstrong, Christopher W. Schultz, Ariana Azimi-Sadjadi, Jonathan R. Brody & Michael J. Pishvaian. (2019) ATM Dysfunction in Pancreatic Adenocarcinoma and Associated Therapeutic Implications. Molecular Cancer Therapeutics 18:11, pages 1899-1908.
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Mei Hua Jin & Do-Youn Oh. (2019) ATM in DNA repair in cancer. Pharmacology & Therapeutics 203, pages 107391.
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Qiang Zhang, Michael D. Green, Xueting Lang, Jenny Lazarus, Joshua D. Parsels, Shuang Wei, Leslie A. Parsels, Jiaqi Shi, Nithya Ramnath, Daniel R. Wahl, Marina Pasca di Magliano, Timothy L. Frankel, Ilona Kryczek, Yu L. Lei, Theodore S. Lawrence, Weiping Zou & Meredith A. Morgan. (2019) Inhibition of ATM Increases Interferon Signaling and Sensitizes Pancreatic Cancer to Immune Checkpoint Blockade Therapy. Cancer Research 79:15, pages 3940-3951.
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Véronique Vendrely, Samuel Amintas, Cécile Noel, Isabelle Moranvillier, Isabelle Lamrissi, Benoit Rousseau, Soulé Coulibaly, Aurélie Bedel, François Moreau-Gaudry, Etienne Buscail, Laurence Chiche, Geneviève Belleannée, Charles Dupin & Sandrine Dabernat. (2019) Combination treatment of resveratrol and capsaicin radiosensitizes pancreatic tumor cells by unbalancing DNA repair response to radiotherapy towards cell death. Cancer Letters 451, pages 1-10.
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Robert Pilarski. (2019) The Role of BRCA Testing in Hereditary Pancreatic and Prostate Cancer Families . American Society of Clinical Oncology Educational Book:39, pages 79-86.
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Rille Pihlak, Jamie Weaver, Juan Valle & Mairéad McNamara. (2018) Advances in Molecular Profiling and Categorisation of Pancreatic Adenocarcinoma and the Implications for Therapy. Cancers 10:1, pages 17.
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Koji ShindoJun YuMasaya SuenagaShahriar FesharakizadehChristy ChoAnne Macgregor-DasAbdulrehman SiddiquiP. Dane WitmerKoji TamuraTae Jun SongJose Alejandro Navarro AlmarioAaron BrantMichael BorgesMadeline FordThomas BarkleyJin HeMatthew J. WeissChristopher L. WolfgangNicholas J. RobertsRalph H. HrubanAlison P. KleinMichael Goggins. (2017) Deleterious Germline Mutations in Patients With Apparently Sporadic Pancreatic Adenocarcinoma. Journal of Clinical Oncology 35:30, pages 3382-3390.
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Yiannis Drosos, David Escobar, Ming-Yi Chiang, Kathryn Roys, Virginia Valentine, Marc B. Valentine, Jerold E. Rehg, Vaibhav Sahai, Lesa A. Begley, Jianming Ye, Leena Paul, Peter J. McKinnon & Beatriz Sosa-Pineda. (2017) ATM-deficiency increases genomic instability and metastatic potential in a mouse model of pancreatic cancer. Scientific Reports 7:1.
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