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Cell Cycle Volume 16, 2017 - Issue 24
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ATM-mediated mitochondrial damage response triggered by nuclear DNA damage in normal human lung fibroblasts

Tsutomu ShimuraDepartment of Environmental Health; National Institute of Public Health 2-3-6 Minami; Wako, Saitama, JapanCorrespondence[email protected]
,
Megumi SasataniDepartment of Experimental Oncology; Research Center for Radiation Genome Medicine; Research Institute for Radiation Biology and Medicine (RIRBM); Hiroshima University, Hiroshima, Japan.
,
Hidehiko KawaiDepartment of Experimental Oncology; Research Center for Radiation Genome Medicine; Research Institute for Radiation Biology and Medicine (RIRBM); Hiroshima University, Hiroshima, Japan.
,
Kenji KamiyaDepartment of Experimental Oncology; Research Center for Radiation Genome Medicine; Research Institute for Radiation Biology and Medicine (RIRBM); Hiroshima University, Hiroshima, Japan.
,
Junya KobayashiDepartment of Genome Dynamics, Radiation Biology Center; Kyoto University; Kyoto, Japan
,
Kenshi KomatsuDepartment of Genome Dynamics, Radiation Biology Center; Kyoto University; Kyoto, Japan
&
Naoki KunugitaDepartment of Environmental Health; National Institute of Public Health 2-3-6 Minami; Wako, Saitama, Japan
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Pages 2345-2354 | Received 07 Jul 2017, Accepted 29 Sep 2017, Published online: 29 Nov 2017

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Tsutomu Shimura, Takahito Ando, Momoka Narao, Megumi Sasatani, Kenji Kamiya & Akira Ushiyama. (2020) Mechanism of turnover or persistence of radiation-induced myofibroblast in vitro. Cell Cycle 19:23, pages 3375-3385.
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Ying Liu, Yunen Liu, Changci Tong, Peifang Cong, Xiuyun Shi, Lin Shi, Mingxiao Hou, Hongxu Jin & Yongli Bao. (2020) Quantitative analysis of the global proteome in lung from mice with blast injury. Experimental Lung Research 46:8, pages 308-319.
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Articles from other publishers (20)

Tsutomu Shimura. (2023) Mitochondrial Signaling Pathways Associated with DNA Damage Responses. International Journal of Molecular Sciences 24:7, pages 6128.
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Tsutomu Shimura, Rina Shiga, Megumi Sasatani, Kenji Kamiya & Akira Ushiyama. (2022) Melatonin and MitoEbselen-2 Are Radioprotective Agents to Mitochondria. Genes 14:1, pages 45.
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T Shimura, E Zaharieva, M Sasatani, H Kawai, K Kamiya & A Ushiyama. (2022) ACTIVATION OF HUMAN FIBROBLASTS BY CHRONIC RADIATION RATHER THAN ACUTE RADIATION. Radiation Protection Dosimetry 198:13-15, pages 1098-1103.
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Xingju Chen, Nanda Karmaker, Pierre Cloutier, Andrew D. Bass, Yi Zheng & Léon Sanche. (2022) Low-Energy Electron Damage to Plasmid DNA in Thin Films: Dependence on Substrates, Surface Density, Charging, Environment, and Uniformity. The Journal of Physical Chemistry B 126:29, pages 5443-5457.
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Tsutomu Shimura, Chinami Nakashiro, Kazusi Fujiwara, Rina Shiga, Megumi Sasatani, Kenji Kamiya & Akira Ushiyama. (2022) Radiation affects glutathione redox reaction by reduced glutathione peroxidase activity in human fibroblasts. Journal of Radiation Research 63:2, pages 183-191.
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C. Kurtman, I. Sokur, O. Martsenius, T. Nesterenko & M.K. Ozbilgin. (2022) Радіаційно-індукована автофагія може оберігати пухлинні клітини від ушкоджень або спричиняти їх апоптоз. Practical oncology 4:3-4, pages 18-25.
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José Antonio Pedroza‐Garcia, Yanli Xiang & Lieven De Veylder. (2021) Cell cycle checkpoint control in response to DNA damage by environmental stresses. The Plant Journal 109:3, pages 490-507.
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Jia Liu, Xiaoxuan Wang, Fei Xue, Ming Zheng & Qingxian Luan. (2021) Abnormal mitochondrial structure and function are retained in gingival tissues and human gingival fibroblasts from patients with chronic periodontitis. Journal of Periodontal Research 57:1, pages 94-103.
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Mikio Shimada & Tomoko Miyake. 2022. Epigenetics and DNA Damage. Epigenetics and DNA Damage 157 166 .
Tsutomu Shimura. (2021) ATM-Mediated Mitochondrial Radiation Responses of Human Fibroblasts. Genes 12:7, pages 1015.
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Tsutomu Shimura. (2021) The role of mitochondrial oxidative stress and the tumor microenvironment in radiation-related cancer. Journal of Radiation Research 62:Supplement_1, pages i36-i43.
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Tsutomu Shimura. 2021. Tumor Microenvironment. Tumor Microenvironment 239 251 .
Yosef Shiloh. (2020) The cerebellar degeneration in ataxia-telangiectasia: A case for genome instability. DNA Repair 95, pages 102950.
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Tsutomu Shimura, Chinami Nakashiro, Momoka Narao & Akira Ushiyama. (2020) Induction of oxidative stress biomarkers following whole-body irradiation in mice. PLOS ONE 15:10, pages e0240108.
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Elisabet Cuyàs, Sara Verdura, Vicente Micol, Jorge Joven, Joaquim Bosch-Barrera, José Antonio Encinar & Javier A. Menendez. (2019) Revisiting silibinin as a novobiocin-like Hsp90 C-terminal inhibitor: Computational modeling and experimental validation. Food and Chemical Toxicology 132, pages 110645.
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Tsutomu Shimura, Mao Koyama, Daiki Aono & Naoki Kunugita. (2019) Epicatechin as a promising agent to countermeasure radiation exposure by mitigating mitochondrial damage in human fibroblasts and mouse hematopoietic cells. The FASEB Journal 33:6, pages 6867-6876.
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José-Antonio Pedroza-García, Manuela Nájera-Martínez, Christelle Mazubert, Paulina Aguilera-Alvarado, Jeannine Drouin-Wahbi, Sobeida Sánchez-Nieto, José M. Gualberto, Cécile Raynaud & Javier Plasencia. (2019) Role of pyrimidine salvage pathway in the maintenance of organellar and nuclear genome integrity. The Plant Journal 97:3, pages 430-446.
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Tsutomu Shimura, Megumi Sasatani, Hidehiko Kawai, Kenji Kamiya, Junya Kobayashi, Kenshi Komatsu & Naoki Kunugita. (2018) Radiation-Induced Myofibroblasts Promote Tumor Growth via Mitochondrial ROS–Activated TGFβ Signaling. Molecular Cancer Research 16:11, pages 1676-1686.
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Yurii Kuzin, Dominika Kappo, Anna Porfireva, Dmitry Shurpik, Ivan Stoikov, Gennady Evtugyn & Tibor Hianik. (2018) Electrochemical DNA Sensor Based on Carbon Black—Poly(Neutral Red) Composite for Detection of Oxidative DNA Damage. Sensors 18:10, pages 3489.
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Yuehua Wei, Lulu Chen, Hui Xu, Conghua Xie, Yunfeng Zhou & Fuxiang Zhou. (2018) Mitochondrial Dysfunctions Regulated Radioresistance through Mitochondria-to-Nucleus Retrograde Signaling Pathway of NF-κB/PI3K/AKT2/mTOR. Radiation Research 190:2, pages 204-215.
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