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The DNA Pol ϵ stimulatory activity of Mrc1 is modulated by phosphorylation

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Pages 64-72 | Received 18 Jul 2017, Accepted 29 Oct 2017, Published online: 21 Dec 2017

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Lanjing Li & Zhihui Zhang. (2020) Recombinant expression and characterization of yeast Mrc1, a DNA replication checkpoint mediator. Preparative Biochemistry & Biotechnology 50:2, pages 198-203.
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Weiwei Zhang, Xin Wen, Xin Fan, Yesong Liang, Yanqiang Li, Shuailong Chen, Yang Yang, Zining Meng, Xiaochun Liu & Jian Luo. (2022) Construction of a high-density genetic linkage map and QTL mapping for growth traits in gynogenetic brown-marbled grouper (Epinephelus fuscoguttatus). Aquaculture 561, pages 738710.
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Richard He & Zhiguo Zhang. (2022) Rad53 arrests leading and lagging strand DNA synthesis via distinct mechanisms in response to DNA replication stress. BioEssays 44:9, pages 2200061.
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Albert Serra-Cardona, Chuanhe YuXinmin Zhang, Xu HuaYuan Yao, Jiaqi Zhou, Haiyun Gan & Zhiguo Zhang. (2021) A mechanism for Rad53 to couple leading- and lagging-strand DNA synthesis under replication stress in budding yeast. Proceedings of the National Academy of Sciences 118:38.
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Allison W McClure & John FX Diffley. (2021) Rad53 checkpoint kinase regulation of DNA replication fork rate via Mrc1 phosphorylation. eLife 10.
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Lionel Gellon, Simran Kaushal, Jorge Cebrián, Mayurika Lahiri, Sergei M Mirkin & Catherine H Freudenreich. (2019) Mrc1 and Tof1 prevent fragility and instability at long CAG repeats by their fork stabilizing function. Nucleic Acids Research 47:2, pages 794-805.
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