Tumor-targeting Salmonella typhimurium A1-R combined with recombinant methioninase and cisplatinum eradicates an osteosarcoma cisplatinum-resistant lung metastasis in a patient-derived orthotopic xenograft (PDOX) mouse model: decoy, trap and kill chemotherapy moves toward the clinic

Kentaro IgarashiAntiCancer, Inc., San Diego, CA, USA;Department of Surgery, University of California, San Diego, CA, USA;Department of Orthopaedic Surgery, Kanazawa University, Kanazawa, JapanView further author information

Kei KawaguchiAntiCancer, Inc., San Diego, CA, USA;Department of Surgery, University of California, San Diego, CA, USAView further author information

Tasuku KiyunaAntiCancer, Inc., San Diego, CA, USA;Department of Surgery, University of California, San Diego, CA, USAView further author information

Kentaro MiyakeAntiCancer, Inc., San Diego, CA, USA;Department of Surgery, University of California, San Diego, CA, USAView further author information

Masuyo MiyakeAntiCancer, Inc., San Diego, CA, USA;Department of Surgery, University of California, San Diego, CA, USAView further author information

Shukuan LiAntiCancer, Inc., San Diego, CA, USAView further author information

Qinghong HanAntiCancer, Inc., San Diego, CA, USAView further author information

Yuying TanAntiCancer, Inc., San Diego, CA, USAView further author information

Ming ZhaoAntiCancer, Inc., San Diego, CA, USAView further author information

Yunfeng LiDept. of Pathology, University of California, Los Angeles, CA, USAView further author information

Scott D. NelsonDept. of Pathology, University of California, Los Angeles, CA, USAView further author information

Sarah M. DryDept. of Pathology, University of California, Los Angeles, CA, USAView further author information

Arun S. SinghDivision of Hematology-Oncology, University of California, Los Angeles, CA, USAView further author information

Irmina A. ElliottDivision of Surgical Oncology, University of California, Los Angeles, CA, USAView further author information

Tara A. RussellDivision of Surgical Oncology, University of California, Los Angeles, CA, USA

http://orcid.org/0000-0002-3912-3601 View further author information

Mark A. EckardtDepartment of Surgery, Yale School of Medicine, New Haven, CT, USA

http://orcid.org/0000-0002-9528-8419 View further author information

Norio YamamotoDepartment of Orthopaedic Surgery, Kanazawa University, Kanazawa, JapanView further author information

Katsuhiro HayashiDepartment of Orthopaedic Surgery, Kanazawa University, Kanazawa, JapanView further author information

Hiroaki KimuraDepartment of Orthopaedic Surgery, Kanazawa University, Kanazawa, JapanView further author information

Shinji MiwaDepartment of Orthopaedic Surgery, Kanazawa University, Kanazawa, JapanView further author information

Hiroyuki TsuchiyaDepartment of Orthopaedic Surgery, Kanazawa University, Kanazawa, JapanCorrespondence[email protected]
View further author information

Fritz C. EilberDivision of Surgical Oncology, University of California, Los Angeles, CA, USACorrespondence[email protected]

http://orcid.org/0000-0003-3336-9333 View further author information

Robert M. HoffmanAntiCancer, Inc., San Diego, CA, USA;Department of Surgery, University of California, San Diego, CA, USACorrespondence[email protected]
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Tumor-targeting Salmonella typhimurium A1-R combined with recombinant methioninase and cisplatinum eradicates an osteosarcoma cisplatinum-resistant lung metastasis in a patient-derived orthotopic xenograft (PDOX) mouse model: decoy, trap and kill chemotherapy moves toward the clinic

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Tumor-targeting Salmonella typhimurium A1-R combined with recombinant methioninase and cisplatinum eradicates an osteosarcoma cisplatinum-resistant lung metastasis in a patient-derived orthotopic xenograft (PDOX) mouse model: decoy, trap and kill chemotherapy moves toward the clinic

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