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Cell Cycle Volume 21, 2022 - Issue 11
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Research Paper

POLG mutations lead to abnormal mitochondrial remodeling during neural differentiation of human pluripotent stem cells via SIRT3/AMPK pathway inhibition

Anbin Chena Department of Neurosurgery, Qilu Hospital and Institute of Brain and Brain-Inspired Science, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, China;b Shandong Key Laboratory of Brain Function Remodeling, Jinan, Shandong Province, China;c Department of Clinical Medicine (K1), University of Bergen, Bergen, NorwayView further author information
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Cecilie Katrin Kristianseni Neuro-SysMed, Center of Excellence for Clinical Research in Neurological Diseases, Department of Neurology, Haukeland University Hospital, Bergen, NorwayView further author information
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Lena Elise HøylandView further author information
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Mathias ZieglerView further author information
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Jian Wanga Department of Neurosurgery, Qilu Hospital and Institute of Brain and Brain-Inspired Science, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, China;b Shandong Key Laboratory of Brain Function Remodeling, Jinan, Shandong Province, China;d Department of Biomedicine, University of Bergen, Bergen, NorwayView further author information
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Gareth John Sullivane Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway;f Institute of Immunology, Oslo University Hospital, Oslo, Norway;g Hybrid Technology Hub Centre of Excellence, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway;h Department of Pediatric Research, Oslo University Hospital, Oslo, NorwayView further author information
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Xingang Lia Department of Neurosurgery, Qilu Hospital and Institute of Brain and Brain-Inspired Science, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, China;b Shandong Key Laboratory of Brain Function Remodeling, Jinan, Shandong Province, ChinaCorrespondence[email protected]
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Laurence A. Bindoffc Department of Clinical Medicine (K1), University of Bergen, Bergen, Norway;i Neuro-SysMed, Center of Excellence for Clinical Research in Neurological Diseases, Department of Neurology, Haukeland University Hospital, Bergen, NorwayCorrespondence[email protected]
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Kristina Xiao Liangc Department of Clinical Medicine (K1), University of Bergen, Bergen, Norway;i Neuro-SysMed, Center of Excellence for Clinical Research in Neurological Diseases, Department of Neurology, Haukeland University Hospital, Bergen, NorwayCorrespondence[email protected]
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Pages 1178-1193 | Received 03 Aug 2021, Accepted 31 Jan 2022, Published online: 17 Mar 2022

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