Advanced search
Publication Cover
COPD: Journal of Chronic Obstructive Pulmonary Disease Volume 5, 2008 - Issue 3
Submit an article Journal homepage
458
Views
33
CrossRef citations to date
0
Altmetric
ORIGINAL RESEARCH

Endothelial Alpha-1-Antitrypsin Attenuates Cigarette Smoke Induced Apoptosis In Vitro

Ruta Aldonyte Pulmonary Division, Department of Medicine, P.O. Box 100225, University of Florida, 1600 SW Archer Rd, Gainesville, Florida, 32610, USA; Research Service, Malcom Randall V. A. Medical Center, Gainesville, Florida, 32608-1197, USA
,
Edgar Tarun Hutchinson Research Service, Malcom Randall V. A. Medical Center, Gainesville, Florida, 32608-1197, USA
,
Bilian Jin Research Service, Malcom Randall V. A. Medical Center, Gainesville, Florida, 32608-1197, USA
,
Mark Brantly Pulmonary Division, Department of Medicine, P.O. Box 100225, University of Florida, 1600 SW Archer Rd, Gainesville, Florida, 32610, USA
,
Edward Block Pulmonary Division, Department of Medicine, P.O. Box 100225, University of Florida, 1600 SW Archer Rd, Gainesville, Florida, 32610, USA; Research Service, Malcom Randall V. A. Medical Center, Gainesville, Florida, 32608-1197, USA
,
Jawaharlal Patel Pulmonary Division, Department of Medicine, P.O. Box 100225, University of Florida, 1600 SW Archer Rd, Gainesville, Florida, 32610, USA; Research Service, Malcom Randall V. A. Medical Center, Gainesville, Florida, 32608-1197, USA
&
Jianliang Zhang Pulmonary Division, Department of Medicine, P.O. Box 100225, University of Florida, 1600 SW Archer Rd, Gainesville, Florida, 32610, USA; Research Service, Malcom Randall V. A. Medical Center, Gainesville, Florida, 32608-1197, USA
 show all
Pages 153-162 | Published online: 02 Jul 2009

Citations (33)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Killian Hurley, Emer P. Reeves, Tomás P. Carroll & Noel G. McElvaney. (2016) Tumor necrosis factor-α driven inflammation in alpha-1 antitrypsin deficiency: a new model of pathogenesis and treatment. Expert Review of Respiratory Medicine 10:2, pages 207-222.
Read now
Mathieu C Morissette, Julie Parent & Julie Milot. (2009) Alveolar epithelial and endothelial cell apoptosis in emphysema: What we know and what we need to know. International Journal of Chronic Obstructive Pulmonary Disease 4, pages 19-31.
Read now

Articles from other publishers (31)

O. E. Akbasheva, L. V. Spirina, D. A. Dyakov & N. V. Masunova. (2022) Proteolysis and Deficiency of α1-Proteinase Inhibitor in SARS-CoV-2 Infection. Biochemistry (Moscow), Supplement Series B: Biomedical Chemistry 16:4, pages 271-291.
Crossref
O.E Akbasheva, L.V. Spirina, D.A. Dyakov & N.V. Masunova. (2022) Proteolysis and deficiency of α1-proteinase inhibitor in SARS-CoV-2 infection. Biomeditsinskaya Khimiya 68:3, pages 157-176.
Crossref
Rebecca P. Chow, Kevin Nguyen, Wenyu Gou, Erica Green, Katherine Morgan, William Lancaster, Kristi Helke, Charlie Strange & Hongjun Wang. (2021) A Novel Cellular Therapy to Treat Pancreatic Pain in Experimental Chronic Pancreatitis Using Human Alpha-1 Antitrypsin Overexpressing Mesenchymal Stromal Cells. Biomedicines 9:11, pages 1695.
Crossref
Zuzana Rabekova, Sona Frankova, Milan Jirsa, Magdalena Neroldova, Mariia Lunova, Ondrej Fabian, Martin Kveton, David Varys, Klara Chmelova, Vera Adamkova, Jaroslav A. Hubacek, Julius Spicak, Dusan Merta & Jan Sperl. (2021) Alpha-1 Antitrypsin and Hepatocellular Carcinoma in Liver Cirrhosis: SERPINA1 MZ or MS Genotype Carriage Decreases the Risk. International Journal of Molecular Sciences 22:19, pages 10560.
Crossref
Lili Song, Wenyu Gou, Jingjing Wang, Hua Wei, Jennifer Lee, Charlie Strange & Hongjun Wang. (2021) Overexpression of alpha-1 antitrypsin in mesenchymal stromal cells improves their intrinsic biological properties and therapeutic effects in nonobese diabetic mice. Stem Cells Translational Medicine 10:2, pages 320-331.
Crossref
Qing Lu, Eric Gottlieb & Sharon Rounds. (2018) Effects of cigarette smoke on pulmonary endothelial cells. American Journal of Physiology-Lung Cellular and Molecular Physiology 314:5, pages L743-L756.
Crossref
Eboni Chambers, Sharon Rounds & Qing Lu. 2018. Molecular and Functional Insights Into the Pulmonary Vasculature. Molecular and Functional Insights Into the Pulmonary Vasculature 63 86 .
Ieva Bruzauskaite, Jovile Raudoniute, Jaroslav Denkovskij, Edvardas Bagdonas, Sandra Meidute-Abaraviciene, Vaida Simonyte, Daiva Bironaite, Almantas Siaurys, Eiva Bernotiene & Ruta Aldonyte. (2016) Native matrix-based human lung alveolar tissue model in vitro: studies of the reparatory actions of mesenchymal stem cells. Cytotechnology 69:1, pages 1-17.
Crossref
Fatma Nihan Turhan Caglar, Vusal Ksanski, Veli Polat, Ismail Ungan, Alev Kural, Serkan Ciftci, Bulent Demir, Murat Ugurlucan, Faruk Akturk & Osman Karakaya. (2016) The Association Between α 1 -Antitrypsin and Coronary Artery Ectasia . Angiology 67:10, pages 927-931.
Crossref
Kevin Ni, Karina A. Serban, Chanan Batra & Irina Petrache. (2016) Alpha-1 Antitrypsin Investigations Using Animal Models of Emphysema. Annals of the American Thoracic Society 13:Supplement_4, pages S311-S316.
Crossref
Adam Wanner. 2016. Alpha-1 Antitrypsin. Alpha-1 Antitrypsin 141 155 .
Xueyuan Zhou, Zhu Liu, Leland Shapiro, Jun Yang & Gregory F Burton. (2015) Low-density lipoprotein receptor-related protein 1 mediates α1-antitrypsin internalization in CD4+ T lymphocytes. Journal of Leukocyte Biology 98:6, pages 1027-1035.
Crossref
Angelia D. LockettDaniela N. PetruscaMatthew J. JusticeChristophe PoirierKarina A. SerbanNatalia I. RushMalgorzata KamockaDan Predescu, Sanda Predescu & Irina Petrache. (2015) Scavenger receptor class B, type I-mediated uptake of A1AT by pulmonary endothelial cells. American Journal of Physiology-Lung Cellular and Molecular Physiology 309:4, pages L425-L434.
Crossref
Ranu Surolia, Suman KarkiHyunki KimZhihong YuTejaswini KulkarniSergey B. MirovA. Brent CarterSteven M. Rowe, Sadis MatalonVictor J. ThannickalAnupam AgarwalVeena B. Antony. (2015) Heme oxygenase-1-mediated autophagy protects against pulmonary endothelial cell death and development of emphysema in cadmium-treated mice. American Journal of Physiology-Lung Cellular and Molecular Physiology 309:3, pages L280-L292.
Crossref
O Guttman, B M Baranovski, R Schuster, Z Kaner, G S Freixo-Lima, N Bahar, N Kalay, M I Mizrahi, I Brami, D E Ochayon & E C Lewis. (2015) Acute-phase protein α1-anti-trypsin: diverting injurious innate and adaptive immune responses from non-authentic threats. Clinical and Experimental Immunology 179:2, pages 161-172.
Crossref
Eileen Frenzel, Sabine Wrenger, Stephan Immenschuh, Rembert Koczulla, Ravi Mahadeva, H. Joachim Deeg, Charles A. Dinarello, Tobias Welte, A. Mario Q. Marcondes & Sabina Janciauskiene. (2014) Acute-Phase Protein α1-Antitrypsin—A Novel Regulator of Angiopoietin-like Protein 4 Transcription and Secretion. The Journal of Immunology 192:11, pages 5354-5362.
Crossref
Angelia D. Lockett, Mary Beth Brown, Nieves Santos-Falcon, Natalia I. Rush, Houssam Oueini, Amber J. Oberle, Esther Bolanis, Miryam A. Fragoso, Daniela N. Petrusca, Karina A. Serban, Kelly S. Schweitzer, Robert G. Presson Jr.Michael Campos & Irina Petrache. (2014) Active Trafficking of Alpha 1 Antitrypsin across the Lung Endothelium. PLoS ONE 9:4, pages e93979.
Crossref
Angelia D. Lockett, Samuel Kimani, Godfrey Ddungu, Sabine Wrenger, Rubin M. Tuder, Sabina M. Janciauskiene & Irina Petrache. (2013) α 1 -Antitrypsin Modulates Lung Endothelial Cell Inflammatory Responses to TNF-α . American Journal of Respiratory Cell and Molecular Biology 49:1, pages 143-150.
Crossref
Anna Linja‐aho, Witold Mazur, Tuula Toljamo, Pentti Nieminen, Steffen Ohlmeier, Mikko Rönty & Vuokko L. Kinnula. (2012) Distribution and levels of alpha‐1‐antitrypsin in the lung and plasma in smokers and chronic obstructive pulmonary disease. APMIS 121:1, pages 11-21.
Crossref
Edward D Chan, Gregory B Pott, Philip E Silkoff, Annemarie H Ralston, Courtney L Bryan & Leland Shapiro. (2012) Alpha-1-antitrypsin inhibits nitric oxide production. Journal of Leukocyte Biology 92:6, pages 1251-1260.
Crossref
Zong-Zhuang Li & Qiu-Yan Dai. (2012) Pathogenesis of Abdominal Aortic Aneurysms: Role of Nicotine and Nicotinic Acetylcholine Receptors. Mediators of Inflammation 2012, pages 1-8.
Crossref
D.I. Krimmer & B.G.G. Oliver. (2011) What can in vitro models of COPD tell us?. Pulmonary Pharmacology & Therapeutics 24:5, pages 471-477.
Crossref
C. Shu, F. Wan & Q. Li. (2011) Autologous Carotid Artery Reconstruction for the Extracranial Internal Carotid Artery Aneurysm in a Patient Combined with Pulmonary Bulla. European Journal of Vascular and Endovascular Surgery 42:1, pages 22-25.
Crossref
James M Duckers, Dennis J Shale, Robert A Stockley, Nichola S Gale, Bronwen AJ Evans, John R Cockcroft & Charlotte E Bolton. (2010) Cardiovascular and musculskeletal co-morbidities in patients with alpha 1 antitrypsin deficiency. Respiratory Research 11:1.
Crossref
Ruta Aldonyte, Virginijus Tunaitis, Andrejus Surovas, Kristina Suriakaite, Akvile Jarmalaviciute, Karl-Eric Magnusson & Augustas Pivoriunas. (2010) Effects of major human antiprotease α-1-antitrypsin on the motility and proliferation of stromal cells from human exfoliated deciduous teeth. Regenerative Medicine 5:4, pages 633-643.
Crossref
Е. А. ГеренгИ. В. СуходолоЛ. М. ОгородоваР. И. ПлешкоЛ. И. ВолковаО. В. КозинаП. А. СеливановаА. Н. ДзюманО. Е. Акбашева. (2009) Роль клеточных и молекулярных мишеней в формировании различных паттернов воспаления при гетерогенных фенотипах тяжелой бронхиальной астмы. PULMONOLOGIYA:5, pages 78-82.
Crossref
Catherine M Greene & Noel G McElvaney. (2009) Proteases and antiproteases in chronic neutrophilic lung disease - relevance to drug discovery. British Journal of Pharmacology 158:4, pages 1048-1058.
Crossref
Sadaf Sohrab, Daniela N. Petrusca, Angelia D. Lockett, Kelly S. Schweitzer, Natalia I. Rush, Yuan Gu, Krzysztof Kamocki, Jana Garrison & Irina Petrache. (2009) Mechanism of α‐1 antitrypsin endocytosis by lung endothelium. The FASEB Journal 23:9, pages 3149-3158.
Crossref
Guadalupe Ortiz-Muñoz, Xavier Houard, Jose-Luis Martín-Ventura, Brian Y. Ishida, Stephane Loyau, Patrick Rossignol, Juan-Antonio Moreno, John P. Kane, Robert J. Chalkley, Alma L. Burlingame, Jean-Baptiste Michel & Olivier Meilhac. (2009) HDL antielastase activity prevents smooth muscle cell anoikis, a potential new antiatherogenic property. The FASEB Journal 23:9, pages 3129-3139.
Crossref
Mehmet Kayrak, Osman Sonmez, Mehmet A. Vatankulu & Mehmet S. Ulgen. (2009) Completely asymptomatic proximal aortic dissection and massive bullous lung disease: coincidence or is there any etiologic link?. European Journal of Cardio-Thoracic Surgery 35:6, pages 1102-1104.
Crossref
Adam Wanner. (2009) COPD. Chest 135:5, pages 1342-1344.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.