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Original Research

Triple Therapy in COPD: What We Know and What We Don't

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Pages 648-662 | Received 24 Aug 2017, Accepted 02 Oct 2017, Published online: 09 Nov 2017

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Marc Miravitlles, Sudeep Acharya, Bhumika Aggarwal, Frederico LA Fernandes, Jorge Dreyse, José R Jardim, Siwasak Juthong, Gur Levy & Martin Sivori. (2023) Clinical Concepts for Triple Therapy Use in Patients with COPD: A Delphi Consensus. International Journal of Chronic Obstructive Pulmonary Disease 18, pages 1853-1866.
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Marc Miravitlles, Katia Verhamme, Peter M A Calverley, Michael Dreher, Valentina Bayer, Asparuh Gardev, Alberto de la Hoz, Jadwiga Wedzicha & David Price. (2022) A Pooled Analysis of Mortality in Patients with COPD Receiving Dual Bronchodilation with and without Additional Inhaled Corticosteroid. International Journal of Chronic Obstructive Pulmonary Disease 17, pages 545-558.
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Bernardino Alcázar-Navarrete, Francisco García-Rio, Guadalupe Sánchez, Esther Mariscal, Andrea García, Maribel Cuesta, Estefany Uría & Marc Miravitlles. (2021) Burden of Disease Among Exacerbating Patients with COPD Treated with Triple Therapy in Spain. International Journal of Chronic Obstructive Pulmonary Disease 16, pages 2149-2161.
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Peter J. Barnes. (2021) Endo-phenotyping of COPD patients. Expert Review of Respiratory Medicine 15:1, pages 27-37.
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Dejan Radovanovic, Marco Contoli, Fabiano Di Marco, Giovanni Sotgiu, Girolamo Pelaia, Fulvio Braido, Angelo Guido Corsico, Claudio Micheletto, Paola Rogliani, Nicola Scichilone, Laura Saderi, Pierachille Santus & Paolo Solidoro. (2019) Clinical and Functional Characteristics of COPD Patients Across GOLD Classifications: Results of a Multicenter Observational Study. COPD: Journal of Chronic Obstructive Pulmonary Disease 16:3-4, pages 215-226.
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Articles from other publishers (23)

Jennifer K. Quint, Amnon Ariel & Peter J. Barnes. (2023) Rational use of inhaled corticosteroids for the treatment of COPD. npj Primary Care Respiratory Medicine 33:1.
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Marc Miravitlles, Kazuto Matsunaga & Michael Dreher. (2023) Stepwise management of COPD: What is next after bronchodilation?. Therapeutic Advances in Respiratory Disease 17.
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Arwel W Jones, Joanne E McKenzie, Christian R Osadnik, Elizabeth Stovold, Narelle S Cox, Angela T Burge, Aroub Lahham, Joanna YT Lee, Mariana Hoffman & Anne E Holland. (2022) Non-pharmacological interventions for the prevention of hospitalisations in stable chronic obstructive pulmonary disease: component network meta-analysis. Cochrane Database of Systematic Reviews 2022:7.
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Vijayamma AjmeraIqbal Mohammed SheikhSumant Kumar Dadhich. (2021) Effectiveness of demonstration on practice regarding pulmonary rehabilitation techniques among patients with chronic obstructive pulmonary disease in selected hospital at Udaipur city, Rajasthan.. International Journal of Nursing Education and Research, pages 403-406.
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Krishna Sriram, Michael B. Insel & Paul A. Insel. (2022) Inhaled β 2 Adrenergic Agonists and Other cAMP-Elevating Agents: Therapeutics for Alveolar Injury and Acute Respiratory Disease Syndrome? . Pharmacological Reviews 73:4, pages 1659-1697.
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Mònica Monteagudo, Miriam Barrecheguren, Iryna Solntseva, Nafeesa Dhalwani, Alison Booth, Alexa Nuñez, Dimitra Lambrelli & Marc Miravitlles. (2021) Clinical characteristics and factors associated with triple therapy use in newly diagnosed patients with COPD. npj Primary Care Respiratory Medicine 31:1.
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Mònica Monteagudo, Alexa Nuñez, Iryna Solntseva, Nafeesa Dhalwani, Alison Booth, Miriam Barrecheguren, Dimitra Lambrelli & Marc Miravitlles. (2021) Treatment Pathways Before and After Triple Therapy in COPD: A Population-based Study in Primary Care in Spain. Archivos de Bronconeumología 57:3, pages 205-213.
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Mònica Monteagudo, Alexa Nuñez, Iryna Solntseva, Nafeesa Dhalwani, Alison Booth, Miriam Barrecheguren, Dimitra Lambrelli & Marc Miravitlles. (2021) Treatment Pathways Before and After Triple Therapy in COPD: A Population-based Study in Primary Care in Spain. Archivos de Bronconeumología (English Edition) 57:3, pages 205-213.
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Daiana Stolz & Marc Miravitlles. (2020) The right treatment for the right patient with COPD: lessons from the IMPACT trial. European Respiratory Journal 55:5, pages 2000881.
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María Montes de Oca, Maria Victorina López Varela, Agustín Acuña, Eduardo Schiavi, Alejandro Casas, Antonio Tokumoto, Carlos A. Torres Duque, Alejandra Ramírez-Venegas, Gabriel García, Aquiles Camelier, Miguel Bergna, Mark Cohen, Efraín Sanchez-Angarita, Santiago Guzmán, Karen Czischke, Manuel Barros & Alejandra Rey. (2020) Incorporando nuevas evidencias sobre medicamentos inhalados en la EPOC. Asociación Latinoamericana de Tórax (ALAT) 2019. Archivos de Bronconeumología 56:2, pages 106-113.
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Maria Montes de Oca, Maria Victorina López Varela, Agustín Acuña, Eduardo Schiavi, Alejandro Casas, Antonio Tokumoto, Carlos A. Torres Duque, Alejandra Ramírez-Venegas, Gabriel García, Aquiles Camelier, Miguel Bergna, Mark Cohen, Efraín Sanchez-Angarita, Santiago Guzmán, Karen Czischke, Manuel Barros & Alejandra Rey. (2020) Incorporating new evidence on inhaled medications in COPD. The latin American chest association (ALAT) 2019. Archivos de Bronconeumología (English Edition) 56:2, pages 106-113.
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Pietro Pirina, Elisabetta Zinellu, Marco Martinetti, Claudia Spada, Barbara Piras, Claudia Collu & Alessandro Giuseppe Fois. (2020) Treatment of COPD and COPD–heart failure comorbidity in primary care in different stages of the disease. Primary Health Care Research & Development 21.
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Jürgen Knobloch, David Jungck, Juliane Kronsbein, Erich Stoelben, Kazuhiro Ito & Andrea Koch. (2019) LABAs and p38MAPK Inhibitors Reverse the Corticosteroid-Insensitivity of IL-8 in Airway Smooth Muscle Cells of COPD. Journal of Clinical Medicine 8:12, pages 2058.
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Pierachille Santus, Matteo Pecchiari, Francesco Tursi, Vincenzo Valenti, Marina Saad & Dejan Radovanovic. (2019) The Airways’ Mechanical Stress in Lung Disease: Implications for COPD Pathophysiology and Treatment Evaluation. Canadian Respiratory Journal 2019, pages 1-8.
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Sergey N. Avdeev & Natal’ya V. Trushenko. (2019) Triple therapy in chronic obstructive pulmonary disease. Russian Pulmonology 29:2, pages 199-206.
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Peter J. Barnes. (2019) Inflammatory endotypes in COPD. Allergy 74:7, pages 1249-1256.
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Luigino Calzetta, Mario Cazzola, Maria Gabriella Matera & Paola Rogliani. (2019) Adding a LAMA to ICS/LABA Therapy. Chest 155:4, pages 758-770.
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Lowie E.G.W. Vanfleteren, Anders Ullman, Anita Nordenson, Anders Andersson, Kristina Andelid & Leonardo M. Fabbri. (2019) Triple therapy (ICS/LABA/LAMA) in COPD: thinking out of the box. ERJ Open Research 5:1, pages 00185-2018.
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Peter J Barnes. 2019. Genomic and Precision Medicine. Genomic and Precision Medicine 383 399 .
Roland SeifertRoland Seifert. 2019. Basic Knowledge of Pharmacology. Basic Knowledge of Pharmacology 181 193 .
Mario Cazzola, Paola Rogliani, Luigino Calzetta & Maria Gabriella Matera. (2018) Triple therapy versus single and dual long-acting bronchodilator therapy in COPD: a systematic review and meta-analysis . European Respiratory Journal 52:6, pages 1801586.
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V. V. Arkhipov. (2018) Prevention of copd exacerbations. Focus on dual bronchodilators. Medical Council:15, pages 8-17.
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Antonio Anzueto & Marc Miravitlles. (2018) Considerations for the Correct Diagnosis of COPD and Its Management With Bronchodilators. Chest 154:2, pages 242-248.
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