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Original Articles

Physiologically Based Modeling of n-Hexane Kinetics in Humans Following Inhalation Exposure at Rest and Under Physical Exertion: Impact on Free 2,5-Hexanedione in Urine and on n-Hexane in Alveolar Air

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Pages 86-97 | Published online: 17 Aug 2010

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Read on this site (5)

Pierre Brochu, Jessie Ménard & Sami Haddad. (2022) Cardiopulmonary parameters and organ blood flows for workers expressed in terms of VO2 for use in physiologically based toxicokinetic modeling. Journal of Toxicology and Environmental Health, Part A 85:8, pages 307-335.
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Josée Dumas-Campagna, Robert Tardif, Ginette Charest-Tardif & Sami Haddad. (2014) Ethanol toxicokinetics resulting from inhalation exposure in human volunteers and toxicokinetic modeling. Inhalation Toxicology 26:2, pages 59-69.
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Irène Sari-Minodier, Ginette Truchon, Ginette Charest-Tardif, Anick Bérubé & Robert Tardif. (2009) The Effect of Workload on Biological Monitoring of Occupational Exposure to Toluene and N-Hexane: Contribution of Physiologically Based Toxicokinetic Modeling. Journal of Occupational and Environmental Hygiene 6:7, pages 415-432.
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Robert Tardif, Véronique Nadeau, Ginette Truchon & Martin Brochu. (2007) Effect of Physical Exertion on the Biological Monitoring of Exposure to Various Solvents Following Exposure by Inhalation in Human Volunteers: II. n-Hexane. Journal of Occupational and Environmental Hygiene 4:7, pages 502-508.
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Ivan Nestorov. (2007) Whole-body physiologically based pharmacokinetic models. Expert Opinion on Drug Metabolism & Toxicology 3:2, pages 235-249.
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Articles from other publishers (6)

Fabiola Salamon, Andrea Martinelli, Andrea Trevisan, Maria Luisa Scapellato, Giovanni Battista Bartolucci & Mariella Carrieri. (2019) Urinary Levels of Free 2,5-Hexanedione in Italian Subjects Non-Occupationally Exposed to n-Hexane. Applied Sciences 9:24, pages 5277.
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. (2011) A Generic, Cross-Chemical Predictive PBTK Model with Multiple Entry Routes Running as Application in MS Excel; Design of the Model and Comparison of Predictions with Experimental Results. The Annals of Occupational Hygiene.
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Feras Khalil & Stephanie Läer. (2011) Physiologically Based Pharmacokinetic Modeling: Methodology, Applications, and Limitations with a Focus on Its Role in Pediatric Drug Development. Journal of Biomedicine and Biotechnology 2011, pages 1-13.
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Toshiaki Yoshida. (2009) Approach to estimation of absorption of aliphatic hydrocarbons diffusing from interior materials in an automobile cabin by inhalation toxicokinetic analysis in rats. Journal of Applied Toxicology 30:1, pages 42-52.
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Brahim Mohammed-Brahim & Alain Garrigou. (2009) Une approche critique du modèle dominant de prévention du risque chimiqueA critical approach to the dominant model of chemical risk prevention: Contribution of ergotoxicologyUna mirada crítica sobre el modelo dominante de prevención del riesgo químico. El aporte de la ergo toxicología. Activites 06:1.
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Douglas O. Johns, William E. Daniell, Danny D. Shen, David A. Kalman, Russell L. Dills & Michael S. Morgan. (2006) Ethanol-Induced Increase in the Metabolic Clearance of 1,1,1-Trichloroethane in Human Volunteers. Toxicological Sciences 92:1, pages 61-70.
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