Citations (60)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (2)
Alison Tyson-Capper & Hannah Gautrey. (2018) Regulation of Mcl-1 alternative splicing by hnRNP F, H1 and K in breast cancer cells. RNA Biology 15:12, pages 1448-1457.
Read now
Read now
Marco Silipo, Hannah Gautrey, Swapna Satam, Thomas Lennard & Alison Tyson-Capper. (2017) How is Herstatin, a tumor suppressor splice variant of the oncogene HER2, regulated?. RNA Biology 14:5, pages 536-543.
Read now
Read now
Articles from other publishers (58)
Ling Li, Jinxia Zheng & Sebastian Oltean. (2023) Regulation of Epithelial-Mesenchymal Transitions by Alternative Splicing: Potential New Area for Cancer Therapeutics. Genes 14:11, pages 2001.
Crossref
Crossref
Sunkyung Choi, Namjoon Cho, Eun-Mi Kim & Kee K. Kim. (2023) The role of alternative pre-mRNA splicing in cancer progression. Cancer Cell International 23:1.
Crossref
Crossref
Dianyang Li, Wenying Yu & Maode Lai. (2023) Towards understandings of serine/arginine-rich splicing factors. Acta Pharmaceutica Sinica B 13:8, pages 3181-3207.
Crossref
Crossref
Shivani Singh, Saurav Panicker & Satish Ramalingam. 2023. Cancer Genes. Cancer Genes
159
222
.
Elizabeth A. Bonner & Stanley C. Lee. (2023) Therapeutic Targeting of RNA Splicing in Cancer. Genes 14:7, pages 1378.
Crossref
Crossref
Qurat Ul Ain Qureshi, Timothy E. Audas, Ryan D. Morin & Krysta M. Coyle. (2023) Emerging roles for heterogeneous ribonuclear proteins in normal and malignant B cells. Biochemistry and Cell Biology 101:2, pages 160-171.
Crossref
Crossref
Sadeeshkumar Velayutham, Trisha Seal, Samaya Danthurthy, Julia Zaias, Keiran S. M. Smalley & Dmitriy Minond. (2023) In Vivo Acute Toxicity Studies of Novel Anti-Melanoma Compounds Downregulators of hnRNPH1/H2. Biomolecules 13:2, pages 349.
Crossref
Crossref
Yingying Che, Mixue Bai, Kun Lu & Lin Fu. (2022) Splicing factor SRSF3 promotes the progression of cervical cancer through regulating DDX5. Molecular Carcinogenesis 62:2, pages 210-223.
Crossref
Crossref
Chaowei Wen, Zhujun Tian, Lan Li, Tongke Chen, Huajian Chen, Jichen Dai, Zhenzhen Liang, Shumei Ma & Xiaodong Liu. (2022) SRSF3 and HNRNPH1 Regulate Radiation-Induced Alternative Splicing of Protein Arginine Methyltransferase 5 in Hepatocellular Carcinoma. International Journal of Molecular Sciences 23:23, pages 14832.
Crossref
Crossref
Manuel D Gahete, Natalia Herman-Sanchez, Antonio C Fuentes-Fayos, Juan L Lopez-Canovas & Raúl M Luque. (2022) Dysregulation of splicing variants and spliceosome components in breast cancer. Endocrine-Related Cancer 29:9, pages R123-R142.
Crossref
Crossref
Xingjia Lu, Jian Zhong, Linlin Liu, Wenzhu Zhang, Shengdi Zhao, Liang Chen, Yuxian Wei, Hong Zhang, Jingxuan Wu, Wenlin Chen & Fei Ge. (2022) The function and regulatory mechanism of RNA-binding proteins in breast cancer and their future clinical treatment prospects. Frontiers in Oncology 12.
Crossref
Crossref
Luisa Kirchhof, Youssef Fouani, Andrea Knau, Galip S. Aslan, Andreas W. Heumüller, Ilka Wittig, Michaela Müller-McNicoll, Stefanie Dimmeler & Nicolas Jaé. (2022) The G3BP1-UPF1-Associated Long Non-Coding RNA CALA Regulates RNA Turnover in the Cytoplasm. Non-Coding RNA 8:4, pages 49.
Crossref
Crossref
Henrik Tonner, Selina Hunn, Nadine Auler, Carsten Schmelter, Vanessa M. Beutgen, Harald D. von Pein, Norbert Pfeiffer & Franz H. Grus. (2022) A Monoclonal Anti-HMGB1 Antibody Attenuates Neurodegeneration in an Experimental Animal Model of Glaucoma. International Journal of Molecular Sciences 23:8, pages 4107.
Crossref
Crossref
Kai Zhang, Anna E. Barry, Ryan Lamm, Keyur Patel, Michelle Schafer & Hien Dang. (2022) The role of RNA binding proteins in hepatocellular carcinoma. Advanced Drug Delivery Reviews 182, pages 114114.
Crossref
Crossref
Anissa Guillemin, Anuj Kumar, Mélanie Wencker & Emiliano P. Ricci. (2022) Shaping the Innate Immune Response Through Post-Transcriptional Regulation of Gene Expression Mediated by RNA-Binding Proteins. Frontiers in Immunology 12.
Crossref
Crossref
Ga Hye Kim & Ilmin Kwon. (2021) Distinct roles of hnRNPH1 low-complexity domains in splicing and transcription. Proceedings of the National Academy of Sciences 118:50.
Crossref
Crossref
Jian Xiong, Yinshuang Chen, Weipeng Wang & Jing Sun. (2021) Biological function and molecular mechanism of SRSF3 in cancer and beyond (Review). Oncology Letters 23:1.
Crossref
Crossref
Vic Hart, Marco Silipo, Swapna Satam, Hannah Gautrey, John Kirby & Alison Tyson-Capper. (2021) HER2-PI9 and HER2-I12: two novel and functionally active splice variants of the oncogene HER2 in breast cancer. Journal of Cancer Research and Clinical Oncology 147:10, pages 2893-2912.
Crossref
Crossref
Weipeng Zhao, Xichuan Li, Weiqi Nian, Jun Wang, Xiaorui Wang, Linlin Sun, Ye Zhu & Zhongsheng Tong. (2021) Ribosome Proteins Represented by RPL27A Mark the Development and Metastasis of Triple-Negative Breast Cancer in Mouse and Human. Frontiers in Cell and Developmental Biology 9.
Crossref
Crossref
Han Wang & Yanxia Jiang. (2021) SRp20: A potential therapeutic target for human tumors. Pathology - Research and Practice 224, pages 153444.
Crossref
Crossref
Shaoyan Xi, Haiping Cai, Jiabin Lu, Yu Zhang, Yanjiao Yu, Furong Chen, Qitao Huang, Fang Wang & Zhongping Chen. (2021) The pseudogene PRELID1P6 promotes glioma progression via the hnHNPH1-Akt/mTOR axis. Oncogene 40:26, pages 4453-4467.
Crossref
Crossref
Harish Joshi, Basavaraj Vastrad, Nidhi Joshi, Chanabasayya Vastrad, Anandkumar Tengli & Iranna Kotturshetti. (2021) Identification of Key Pathways and Genes in Obesity Using Bioinformatics Analysis and Molecular Docking Studies. Frontiers in Endocrinology 12.
Crossref
Crossref
Jun-Xian Du, Gui-Qi Zhu, Jia-Liang Cai, Biao Wang, Yi-Hong Luo, Cong Chen, Cheng-Zhe Cai, Si-Jia Zhang, Jian Zhou, Jia Fan, Wei Zhu & Zhi Dai. (2021) Splicing factors: Insights into their regulatory network in alternative splicing in cancer. Cancer Letters 501, pages 83-104.
Crossref
Crossref
Jiawei Zhou, Yugang Guo, Zheng Huo, Yuxin Xing, Jintao Fang, Guohui Ma, Qinghui Han, Mengzhen Wang & Qian Xu. (2021) Identification of therapeutic targets and prognostic biomarkers from the hnRNP family in invasive breast carcinoma. Aging 13:3, pages 4503-4521.
Crossref
Crossref
Ji-Lin Wang, Chun-Rong Guo, Tian-Tian Sun, Wen-Yu Su, Qiang Hu, Fang-Fang Guo, Lun-Xi Liang, Jie Xu, Hua Xiong & Jing-Yuan Fang. (2020) SRSF3 functions as an oncogene in colorectal cancer by regulating the expression of ArhGAP30. Cancer Cell International 20:1.
Crossref
Crossref
Vic Hart, Hannah Gautrey, John Kirby & Alison Tyson-Capper. (2020) HER2 splice variants in breast cancer: investigating their impact on diagnosis and treatment outcomes. Oncotarget 11:46, pages 4338-4357.
Crossref
Crossref
Zhixia Zhou, Qi Gong, Zhijuan Lin, Yin Wang, Mengkun Li, Lu Wang, Hongfei Ding & Peifeng Li. (2020) Emerging Roles of SRSF3 as a Therapeutic Target for Cancer. Frontiers in Oncology 10.
Crossref
Crossref
María F. Chervo, Rosalía I. Cordo Russo, Ezequiel Petrillo, Franco Izzo, Mara De Martino, Nicolás Bellora, Mauro E. Cenciarini, Violeta A. Chiauzzi, Lucía Santa María de la Parra, Matías G. Pereyra, Leandro N. Güttlein, Osvaldo L. Podhajcer, José L. Daniotti, Agustina Dupont, Sabrina Barchuk, Silvina Figurelli, Daniel Lopez Della Vecchia, Juan C. Roa, Pablo Guzmán, Cecilia J. Proietti, Roxana Schillaci & Patricia V. Elizalde. (2020) Canonical ErbB-2 isoform and ErbB-2 variant c located in the nucleus drive triple negative breast cancer growth. Oncogene 39:39, pages 6245-6262.
Crossref
Crossref
Shrikant Pawar, Tuck Onn Liew, Aditya Stanam & Chandrajit Lahiri. (2020) Common cancer biomarkers of breast and ovarian types identified through artificial intelligence. Chemical Biology & Drug Design 96:3, pages 995-1004.
Crossref
Crossref
Harvey W. SmithLei YangChen LingArlan WalshVictor D. MartinezJonathan Boucher, Dongmei ZuoEthan S. SokolDean C. PavlickGarrett M. Frampton, Juliann ChmieleckiLaura M. Jones, Philippe P. Roux, William W. LockwoodWilliam J. Muller. (2020) An ErbB2 splice variant lacking exon 16 drives lung carcinoma. Proceedings of the National Academy of Sciences 117:33, pages 20139-20148.
Crossref
Crossref
Jian-Rong Sun, Chen-Fan Kong, Yan-Ni Lou, Ran Yu, Xiang-Ke Qu & Li-Qun Jia. (2020) Genome-Wide Profiling of Alternative Splicing Signature Reveals Prognostic Predictor for Esophageal Carcinoma. Frontiers in Genetics 11.
Crossref
Crossref
Jessica Rea, Valentina Menci, Paolo Tollis, Tiziana Santini, Alexandros Armaos, Maria Giovanna Garone, Federica Iberite, Andrea Cipriano, Gian Gaetano Tartaglia, Alessandro Rosa, Monica Ballarino, Pietro Laneve & Elisa Caffarelli. (2020) HOTAIRM1 regulates neuronal differentiation by modulating NEUROGENIN 2 and the downstream neurogenic cascade. Cell Death & Disease 11:7.
Crossref
Crossref
Toshihiko Takeiwa, Yuichi Mitobe, Kazuhiro Ikeda, Kuniko Horie-Inoue & Satoshi Inoue. (2020) Roles of Splicing Factors in Hormone-Related Cancer Progression. International Journal of Molecular Sciences 21:5, pages 1551.
Crossref
Crossref
Fei Qi, Yong Li, Xue Yang, Yan-Ping Wu, Lian-Jun Lin & Xin-Min Liu. (2020) Significance of alternative splicing in cancer cells. Chinese Medical Journal 133:2, pages 221-228.
Crossref
Crossref
Jihua Guo, Xiaole Wang, Jun Jia & Rong Jia. (2020) Underexpression of SRSF3 and its target gene RBMX predicts good prognosis in patients with head and neck cancer. Journal of Oral Science 62:2, pages 175-179.
Crossref
Crossref
Juan M. Jiménez-Vacas, Vicente Herrero-Aguayo, Antonio J. Montero-Hidalgo, Enrique Gómez-Gómez, Antonio C. Fuentes-Fayos, Antonio J. León-González, Prudencio Sáez-Martínez, Emilia Alors-Pérez, Sergio Pedraza-Arévalo, Teresa González-Serrano, Oscar Reyes, Ana Martínez-López, Rafael Sánchez-Sánchez, Sebastián Ventura, Elena M. Yubero-Serrano, María J. Requena-Tapia, Justo P. Castaño, Manuel D. Gahete & Raúl M. Luque. (2020) Dysregulation of the splicing machinery is directly associated to aggressiveness of prostate cancer. EBioMedicine 51, pages 102547.
Crossref
Crossref
Min-Joo Kang & Mi-Young Lee. (2019) Toxicoproteomic analysis of deltamethrin exposure in neuroblastoma cell lines. Molecular & Cellular Toxicology 16:1, pages 93-101.
Crossref
Crossref
Carla Neckles, Robert E. Boer, Nicholas Aboreden, Allison M. Cross, Robert L. Walker, Bong-Hyun Kim, Suntae Kim, John S. SchneeklothJr.Jr. & Natasha J. Caplen. (2019) HNRNPH1-dependent splicing of a fusion oncogene reveals a targetable RNA G-quadruplex interaction. RNA 25:12, pages 1731-1750.
Crossref
Crossref
A. P. Toptygina, R. Sh. Zakirov, K. S. Kapitanova & E. L. Semikina. (2019) Detection of Small Subsets of CD4+ Lymphocytes with SmartFlare Nanoprobes. Bulletin of Experimental Biology and Medicine 168:2, pages 270-274.
Crossref
Crossref
Quan Yang, Jinyao Zhao, Wenjing Zhang, Dan Chen & Yang Wang. (2019) Aberrant alternative splicing in breast cancer. Journal of Molecular Cell Biology 11:10, pages 920-929.
Crossref
Crossref
James T. DeLigio, Shaun C. Stevens, Gina S. Nazario-Muñoz, H. Patrick MacKnight, Keli K. Doe, Charles E. Chalfant & Margaret A. Park. (2019) Serine/Arginine–Rich Splicing Factor 3 Modulates the Alternative Splicing of Cytoplasmic Polyadenylation Element Binding Protein 2. Molecular Cancer Research 17:9, pages 1920-1930.
Crossref
Crossref
Lorenzo Castagnoli, Michael Ladomery, Elda Tagliabue & Serenella M. Pupa. (2019) The d16HER2 Splice Variant: A Friend or Foe of HER2-Positive Cancers?. Cancers 11:7, pages 902.
Crossref
Crossref
Kiyoshi Masuda & Yuki Kuwano. (2018) Diverse roles of RNA‐binding proteins in cancer traits and their implications in gastrointestinal cancers. WIREs RNA 10:3.
Crossref
Crossref
Nikolai Genov, Alireza Basti, Mónica Abreu & Angela Relógio. (2019) Temporal Splicing Switches in Elements of the TNF-Pathway Identified by Computational Analysis of Transcriptome Data for Human Cell Lines. International Journal of Molecular Sciences 20:5, pages 1182.
Crossref
Crossref
Allison E. Reeme, Tiffany A. Claeys, Praful Aggarwal, Amy J. Turner, John M. Routes, Ulrich Broeckel & Richard T. Robinson. (2018) Human IL12RB1 expression is allele-biased and produces a novel IL12 response regulator. Genes & Immunity 20:3, pages 181-197.
Crossref
Crossref
Yanan Sun, Hai Chen, Yan Lu, Jianying Duo, Lin Lei, Yasheng OuYang, Yifeng Hao, Yuwei Da & Xin-Ming Shen. (2019) Limb girdle muscular dystrophy D3 HNRNPDL related in a Chinese family with distal muscle weakness caused by a mutation in the prion-like domain. Journal of Neurology 266:2, pages 498-506.
Crossref
Crossref
Wen-Sen Pi, Zhi-Yuan Cao, Jia-Ming Liu, Ai-Fen Peng, Wen-Zhao Chen, Jiang-Wei Chen, Shan-Hu Huang & Zhi-Li Liu. (2019) Potential Molecular Mechanisms of AURKB in the Oncogenesis and Progression of Osteosarcoma Cells: A Label-Free Quantitative Proteomics Analysis. Technology in Cancer Research & Treatment 18, pages 153303381985326.
Crossref
Crossref
Yuki Kuranaga, Nobuhiko Sugito, Haruka Shinohara, Takuya Tsujino, Kohei Taniguchi, Kazumasa Komura, Yuko Ito, Tomoyoshi Soga & Yukihiro Akao. (2018) SRSF3, a Splicer of the PKM Gene, Regulates Cell Growth and Maintenance of Cancer-Specific Energy Metabolism in Colon Cancer Cells. International Journal of Molecular Sciences 19:10, pages 3012.
Crossref
Crossref
Laura M. Urbanski, Nathan Leclair & Olga Anczuków. (2018) Alternative‐splicing defects in cancer: Splicing regulators and their downstream targets, guiding the way to novel cancer therapeutics. WIREs RNA 9:4.
Crossref
Crossref
Hao KeLimin ZhaoHonglei ZhangXu FengHaibo XuJunjun HaoShaowei WangQin YangLi ZouXiaosan SuLiqiong WangChunlian WuYang WangJianyun NieBaowei Jiao. (2018) Loss of TDP43 inhibits progression of triple-negative breast cancer in coordination with SRSF3. Proceedings of the National Academy of Sciences 115:15.
Crossref
Crossref
Nancy Martinez-Montiel, Nora Rosas-Murrieta, Maricruz Anaya Ruiz, Eduardo Monjaraz-Guzman & Rebeca Martinez-Contreras. (2018) Alternative Splicing as a Target for Cancer Treatment. International Journal of Molecular Sciences 19:2, pages 545.
Crossref
Crossref
Alicja Czubaty & Agnieszka Piekiełko-Witkowska. (2017) Protein kinases that phosphorylate splicing factors: Roles in cancer development, progression and possible therapeutic options. The International Journal of Biochemistry & Cell Biology 91, pages 102-115.
Crossref
Crossref
Hye Ree Kim, Su Jin Hwang, Chang Hoon Shin, Kyung Hee Choi, Takbum Ohn & Hyeon Ho Kim. (2017) SRSF3-regulated miR-132/212 controls cell migration and invasion by targeting YAP1. Experimental Cell Research 358:2, pages 161-170.
Crossref
Crossref
Bruno Pereira, Marc Billaud & Raquel Almeida. (2017) RNA-Binding Proteins in Cancer: Old Players and New Actors. Trends in Cancer 3:7, pages 506-528.
Crossref
Crossref
Na Tian, Jialiang Li, Jinming Shi & Guangchao Sui. (2017) From General Aberrant Alternative Splicing in Cancers and Its Therapeutic Application to the Discovery of an Oncogenic DMTF1 Isoform. International Journal of Molecular Sciences 18:3, pages 191.
Crossref
Crossref
J Turpin, C Ling, E J Crosby, Z C Hartman, A M Simond, L A Chodosh, J P Rennhack, E R Andrechek, J Ozcelik, M Hallett, G B Mills, R D Cardiff, J W Gray, O L Griffith & W J Muller. (2016) The ErbB2ΔEx16 splice variant is a major oncogenic driver in breast cancer that promotes a pro-metastatic tumor microenvironment. Oncogene 35:47, pages 6053-6064.
Crossref
Crossref
Benjamin P. Lee, Luke C. Pilling, Florence Emond, Kevin Flurkey, David E. Harrison, Rong Yuan, Luanne L. Peters, George A. Kuchel, Luigi Ferrucci, David Melzer & Lorna W. Harries. (2016) Changes in the expression of splicing factor transcripts and variations in alternative splicing are associated with lifespan in mice and humans. Aging Cell 15:5, pages 903-913.
Crossref
Crossref
Thomas Geuens, Delphine Bouhy & Vincent Timmerman. (2016) The hnRNP family: insights into their role in health and disease. Human Genetics 135:8, pages 851-867.
Crossref
Crossref