3,301
Views
26
CrossRef citations to date
0
Altmetric
Point of View

Readthrough transcription: How are DoGs made and what do they do?

&
Pages 632-636 | Received 23 Nov 2015, Accepted 28 Jan 2016, Published online: 27 May 2016

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (1)

Andrea Barta & Michael F. Jantsch. (2017) RNA in Disease and development. RNA Biology 14:5, pages 457-459.
Read now

Articles from other publishers (25)

Lara Djakovic, Thomas Hennig, Katharina Reinisch, Andrea Milić, Adam W. Whisnant, Katharina Wolf, Elena Weiß, Tobias Haas, Arnhild Grothey, Christopher S. Jürges, Michael Kluge, Elmar Wolf, Florian Erhard, Caroline C. Friedel & Lars Dölken. (2023) The HSV-1 ICP22 protein selectively impairs histone repositioning upon Pol II transcription downstream of genes. Nature Communications 14:1.
Crossref
Miguel Montez, Maria Majchrowska, Michal Krzyszton, Grzegorz Bokota, Sebastian Sacharowski, Magdalena Wrona, Ruslan Yatusevich, Ferran Massana, Dariusz Plewczynski & Szymon Swiezewski. (2023) Promoter‐pervasive transcription causes RNA polymerase II pausing to boost DOG1 expression in response to salt . The EMBO Journal 42:5.
Crossref
Fumiaki Uchiumi. 2023. Bidirectional Gene Promoters. Bidirectional Gene Promoters 143 155 .
Raven Shah, Christian M. Gallardo, Yoonhee H. Jung, Ben Clock, Jesse R. Dixon, William M. McFadden, Kinjal Majumder, David J. Pintel, Victor G. Corces, Bruce E. Torbett, Philip R. Tedbury & Stefan G. Sarafianos. (2022) Activation of HIV-1 proviruses increases downstream chromatin accessibility. iScience 25:12, pages 105490.
Crossref
James M. Burke, Nina Ripin, Max B. Ferretti, Laura A. St Clair, Emma R. Worden-Sapper, Fernando Salgado, Sara L. Sawyer, Rushika Perera, Kristen W. Lynch & Roy Parker. (2022) RNase L activation in the cytoplasm induces aberrant processing of mRNAs in the nucleus. PLOS Pathogens 18:11, pages e1010930.
Crossref
Marc Morgan, Ramin Shiekhattar, Ali Shilatifard & Shannon M. Lauberth. (2022) It’s a DoG-eat-DoG world—altered transcriptional mechanisms drive downstream-of-gene (DoG) transcript production. Molecular Cell 82:11, pages 1981-1991.
Crossref
Nicolle A. Rosa-Mercado & Joan A. Steitz. (2022) Who let the DoGs out? – biogenesis of stress-induced readthrough transcripts. Trends in Biochemical Sciences 47:3, pages 206-217.
Crossref
Lucas Ferreira Dasilva, Ezra Blumenthal, Felipe Beckedorff, Pradeep Reddy CingaramHelena Gomes Dos SantosRaghu Ram EdupugantiAnda Zhang, Sadat DokaneheifardYuki Aoi, Jingyin Yue, Nina KirsteinMina Masoumeh Tayari, Ali Shilatifard & Ramin Shiekhattar. (2021) Integrator enforces the fidelity of transcriptional termination at protein-coding genes. Science Advances 7:45.
Crossref
Virginia Giuliani, Meredith A. Miller, Chiu-Yi Liu, Stella R. Hartono, Caleb A. Class, Christopher A. Bristow, Erika Suzuki, Lionel A. Sanz, Guang Gao, Jason P. Gay, Ningping Feng, Johnathon L. Rose, Hideo Tomihara, Joseph R. Daniele, Michael D. Peoples, Jennifer P. Bardenhagen, Mary K. Geck Do, Qing E. Chang, Bhavatarini Vangamudi, Christopher Vellano, Haoqiang Ying, Angela K. Deem, Kim-Anh Do, Giannicola Genovese, Joseph R. Marszalek, Jeffrey J. Kovacs, Michael Kim, Jason B. Fleming, Ernesto Guccione, Andrea Viale, Anirban Maitra, M. Emilia Di Francesco, Timothy A. Yap, Philip Jones, Giulio Draetta, Alessandro Carugo, Frederic Chedin & Timothy P. Heffernan. (2021) PRMT1-dependent regulation of RNA metabolism and DNA damage response sustains pancreatic ductal adenocarcinoma. Nature Communications 12:1.
Crossref
Kyu-Hyeon Yeom, Zhicheng Pan, Chia-Ho Lin, Han Young Lim, Wen Xiao, Yi Xing & Douglas L. Black. (2021) Tracking pre-mRNA maturation across subcellular compartments identifies developmental gene regulation through intron retention and nuclear anchoring. Genome Research 31:6, pages 1106-1119.
Crossref
Nicolle A. Rosa-Mercado, Joshua T. Zimmer, Maria Apostolidi, Jesse Rinehart, Matthew D. Simon & Joan A. Steitz. (2021) Hyperosmotic stress alters the RNA polymerase II interactome and induces readthrough transcription despite widespread transcriptional repression. Molecular Cell 81:3, pages 502-513.e4.
Crossref
Patrick J. Monnahan, Jean-Michel Michno, Christine O’Connor, Alex B. Brohammer, Nathan M. Springer, Suzanne E. McGaugh & Candice N. Hirsch. (2020) Using multiple reference genomes to identify and resolve annotation inconsistencies. BMC Genomics 21:1.
Crossref
Sara Clohisey, Nicholas Parkinson, Bo Wang, Nicolas Bertin, Helen Wise, Andru Tomoiu, Kim M. Summers, Ross W. Hendry, Piero Carninci, Alistair R. R. Forrest, Yoshihide Hayashizaki, Paul Digard, David A. Hume & J. Kenneth Baillie. (2020) Comprehensive Characterization of Transcriptional Activity during Influenza A Virus Infection Reveals Biases in Cap-Snatching of Host RNA Sequences. Journal of Virology 94:10.
Crossref
Katia Cappelli, Samanta Mecocci, Silvia Gioiosa, Andrea Giontella, Maurizio Silvestrelli, Raffaele Cherchi, Alessio Valentini, Giovanni Chillemi & Stefano Capomaccio. (2020) Gallop Racing Shifts Mature mRNA towards Introns: Does Exercise-Induced Stress Enhance Genome Plasticity?. Genes 11:4, pages 410.
Crossref
Anthony Khong & Roy Parker. (2020) The landscape of eukaryotic mRNPs. RNA 26:3, pages 229-239.
Crossref
R C Stan, C Pinto Bonin, R Porto, F G Soriano & M M de Camargo. (2019) Increased grp78 transcription is correlated to reduced tlr4 transcription in patients surviving sepsis . Clinical and Experimental Immunology 198:2, pages 273-280.
Crossref
Katarzyna Chwalenia, Fujun Qin, Sandeep Singh & Hui Li. (2019) A cell-based splicing reporter system to identify regulators of cis-splicing between adjacent genes. Nucleic Acids Research 47:4, pages e24-e24.
Crossref
Yuval Wiesel, Niv Sabath & Reut Shalgi. (2018) DoGFinder: a software for the discovery and quantification of readthrough transcripts from RNA-seq. BMC Genomics 19:1.
Crossref
David L.V. Bauer, Michael Tellier, Mónica Martínez-Alonso, Takayuki Nojima, Nick J. Proudfoot, Shona Murphy & Ervin Fodor. (2018) Influenza Virus Mounts a Two-Pronged Attack on Host RNA Polymerase II Transcription. Cell Reports 23:7, pages 2119-2129.e3.
Crossref
Yan He, Chengfu Yuan, Lichan Chen, Mingjuan Lei, Lucas Zellmer, Hai Huang & Dezhong Liao. (2018) Transcriptional-Readthrough RNAs Reflect the Phenomenon of “A Gene Contains Gene(s)” or “Gene(s) within a Gene” in the Human Genome, and Thus Are Not Chimeric RNAs. Genes 9:1, pages 40.
Crossref
Katarzyna Chwalenia, Fujun Qin, Sandeep Singh, Panjapon Tangtrongstittikul & Hui Li. (2017) Connections between Transcription Downstream of Genes and cis-SAGe Chimeric RNA. Genes 8:11, pages 338.
Crossref
Anna VilborgNiv Sabath, Yuval Wiesel, Jenny NathansFlonia Levy-Adam, Therese A. YarioJoan A. SteitzReut Shalgi. (2017) Comparative analysis reveals genomic features of stress-induced transcriptional readthrough. Proceedings of the National Academy of Sciences 114:40.
Crossref
Yong Xue, Suman K. Pradhan, Fei Sun, Constantinos Chronis, Nancy Tran, Trent Su, Christopher Van, Ajay Vashisht, James Wohlschlegel, Craig L. Peterson, H.T. Marc Timmers, Siavash K. Kurdistani & Michael F. Carey. (2017) Mot1, Ino80C, and NC2 Function Coordinately to Regulate Pervasive Transcription in Yeast and Mammals. Molecular Cell 67:4, pages 594-607.e4.
Crossref
Scott N. Ashley, Suryanarayan Somanathan, Christian Hinderer, Maxwell Arias, Deirdre McMenamin, Christine Draper & James M. Wilson. (2017) Alternative Start Sites Downstream of Non-Sense Mutations Drive Antigen Presentation and Tolerance Induction to C-Terminal Epitopes. The Journal of Immunology 198:12, pages 4581-4587.
Crossref
Travis J. Loya & Daniel Reines. (2016) Recent advances in understanding transcription termination by RNA polymerase II. F1000Research 5, pages 1478.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.