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RNA Biology Volume 13, 2016 - Issue 7
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Research Paper

Coupling between alternative polyadenylation and alternative splicing is limited to terminal introns

Maliheh MovassatDepartment of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, CA, USAORCID Iconhttps://orcid.org/0000-0002-9798-4434
ORCID Icon,
Tara L. CrabbInstitute of Molecular Biology (IMB), Mainz, Germany
,
Anke BuschDepartment of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, CA, USA;Institute of Molecular Biology (IMB), Mainz, GermanyORCID Iconhttps://orcid.org/0000-0002-2232-1329
ORCID Icon,
Chengguo YaoDepartment of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, CA, USAORCID Iconhttps://orcid.org/0000-0001-9224-0156
ORCID Icon,
Derrick J. ReynoldsDepartment of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, CA, USA
,
Yongsheng ShiDepartment of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, CA, USA
&
Klemens J. HertelDepartment of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, CA, USACorrespondence[email protected]
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Pages 646-655 | Received 02 Dec 2015, Accepted 12 May 2016, Published online: 01 Jul 2016

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Carmen Mora Gallardo, Ainhoa Sánchez de Diego, Carlos Martínez-A & Karel H.M. van Wely. (2021) Interplay between splicing and transcriptional pausing exerts genome-wide control over alternative polyadenylation. Transcription 12:2-3, pages 55-71.
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Articles from other publishers (22)

Jun Cao & Muge N Kuyumcu-Martinez. (2023) Alternative polyadenylation regulation in cardiac development and cardiovascular disease. Cardiovascular Research 119:6, pages 1324-1335.
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Weimin Zhong, Yulong Wu, Maoshu Zhu, Hongbin Zhong, Chaoqun Huang, Yao Lin & Jiyi Huang. (2022) Alternative splicing and alternative polyadenylation define tumor immune microenvironment and pharmacogenomic landscape in clear cell renal carcinoma. Molecular Therapy - Nucleic Acids 27, pages 927-946.
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Zhongxin Jin, Xinning Lv, Yushuai Sun, Zongbao Fan, Guangqing Xiang & Yuxin Yao. (2021) Comprehensive discovery of salt-responsive alternative splicing events based on Iso-Seq and RNA-seq in grapevine roots. Environmental and Experimental Botany 192, pages 104645.
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Dirk Roos & Martin de Boer. (2021) Mutations in cis that affect mRNA synthesis, processing and translation. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1867:9, pages 166166.
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Virginia Giuliani, Meredith A. Miller, Chiu-Yi Liu, Stella R. Hartono, Caleb A. Class, Christopher A. Bristow, Erika Suzuki, Lionel A. Sanz, Guang Gao, Jason P. Gay, Ningping Feng, Johnathon L. Rose, Hideo Tomihara, Joseph R. Daniele, Michael D. Peoples, Jennifer P. Bardenhagen, Mary K. Geck Do, Qing E. Chang, Bhavatarini Vangamudi, Christopher Vellano, Haoqiang Ying, Angela K. Deem, Kim-Anh Do, Giannicola Genovese, Joseph R. Marszalek, Jeffrey J. Kovacs, Michael Kim, Jason B. Fleming, Ernesto Guccione, Andrea Viale, Anirban Maitra, M. Emilia Di Francesco, Timothy A. Yap, Philip Jones, Giulio Draetta, Alessandro Carugo, Frederic Chedin & Timothy P. Heffernan. (2021) PRMT1-dependent regulation of RNA metabolism and DNA damage response sustains pancreatic ductal adenocarcinoma. Nature Communications 12:1.
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Pia Sommerkamp, Nina Cabezas-Wallscheid & Andreas Trumpp. (2021) Alternative Polyadenylation in Stem Cell Self-Renewal and Differentiation. Trends in Molecular Medicine 27:7, pages 660-672.
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Svetlana Kalmykova, Marina Kalinina, Stepan Denisov, Alexey Mironov, Dmitry Skvortsov, Roderic Guigó & Dmitri Pervouchine. (2021) Conserved long-range base pairings are associated with pre-mRNA processing of human genes. Nature Communications 12:1.
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Fanggang Ren, Na Zhang, Lan Zhang, Eric Miller & Jeffrey J. Pu. (2020) Alternative Polyadenylation: a new frontier in post transcriptional regulation. Biomarker Research 8:1.
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Jian Zhang, Yi-Zhe Zhang, Jing Jiang & Cheng-Guo Duan. (2020) The Crosstalk Between Epigenetic Mechanisms and Alternative RNA Processing Regulation. Frontiers in Genetics 11.
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Chen-Hsuin Lee & Finn Grey. (2020) Systems Virology and Human Cytomegalovirus: Using High Throughput Approaches to Identify Novel Host-Virus Interactions During Lytic Infection. Frontiers in Cellular and Infection Microbiology 10.
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Ken-ichi Fujita, Takaki Ishizuka, Mizuki Mitsukawa, Masashi Kurata & Seiji Masuda. (2020) Regulating Divergent Transcriptomes through mRNA Splicing and Its Modulation Using Various Small Compounds. International Journal of Molecular Sciences 21:6, pages 2026.
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Zehra Jafar, Salma Tariq, Irfan Sadiq, Tayyab Nawaz & Malik Nadeem Akhtar. (2019) Genome-Wide Profiling of Polyadenylation Events in Maize Using High-Throughput Transcriptomic Sequences. G3 Genes|Genomes|Genetics 9:8, pages 2749-2760.
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Kevin C. H. Ha, Benjamin J. Blencowe & Quaid Morris. (2018) QAPA: a new method for the systematic analysis of alternative polyadenylation from RNA-seq data. Genome Biology 19:1.
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Lydia Herzel, Korinna Straube & Karla M. Neugebauer. (2018) Long-read sequencing of nascent RNA reveals coupling among RNA processing events. Genome Research 28:7, pages 1008-1019.
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Marius Wegener & Michaela Müller-McNicoll. (2018) Nuclear retention of mRNAs – quality control, gene regulation and human disease. Seminars in Cell & Developmental Biology 79, pages 131-142.
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Rachael Emily Turner, Andrew David Pattison & Traude Helene Beilharz. (2018) Alternative polyadenylation in the regulation and dysregulation of gene expression. Seminars in Cell & Developmental Biology 75, pages 61-69.
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Yunwu Wang, Yu Xu, Wei Yan, Ping Han, Jingmei Liu, Jin Gong, Dongxiao Li, Xiangming Ding, Han Wang, Zhuoying Lin, Dean Tian & Jiazhi Liao. (2018) CFIm25 inhibits hepatocellular carcinoma metastasis by suppressing the p38 and JNK/c-Jun signaling pathways. Oncotarget 9:14, pages 11783-11793.
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Martin Turner & Manuel D. Díaz-Muñoz. (2018) RNA-binding proteins control gene expression and cell fate in the immune system. Nature Immunology 19:2, pages 120-129.
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Tatsiana V. Ramanouskaya & Vasily V. Grinev. (2017) The determinants of alternative RNA splicing in human cells. Molecular Genetics and Genomics 292:6, pages 1175-1195.
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Erik van der Wal, Atze J. Bergsma, Joon M. Pijnenburg, Ans T. van der Ploeg & W.W.M. Pim Pijnappel. (2017) Antisense Oligonucleotides Promote Exon Inclusion and Correct the Common c.-32-13T>G GAA Splicing Variant in Pompe Disease. Molecular Therapy - Nucleic Acids 7, pages 90-100.
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Anke E.E.G. Gudde, Ingeborg D.G. van Kessel, Laurène M. André, Bé Wieringa & Derick G. Wansink. (2017) Trinucleotide-repeat expanded and normal DMPK transcripts contain unusually long poly(A) tails despite differential nuclear residence. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1860:6, pages 740-749.
Crossref
Boxuan Simen Zhao, Ian A. Roundtree & Chuan He. (2016) Post-transcriptional gene regulation by mRNA modifications. Nature Reviews Molecular Cell Biology 18:1, pages 31-42.
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