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Research Article

Trichloroethylene Alters Central and Peripheral Immune Function in Autoimmune-Prone MRL+/+ Mice Following Continuous Developmental and Early Life Exposure

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Pages 129-141 | Received 06 Oct 2006, Accepted 08 Dec 2006, Published online: 09 Oct 2008

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Read on this site (5)

Josue D. Ordaz, Nur P. Damayanti & Joseph M. K. Irudayaraj. (2017) Toxicological effects of trichloroethylene exposure on immune disorders. Immunopharmacology and Immunotoxicology 39:6, pages 305-317.
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Jacqueline R. Meadows, Chevonne Parker, Kathleen M. Gilbert, Sarah J. Blossom & Jamie C. DeWitt. (2017) A single dose of trichloroethylene given during development does not substantially alter markers of neuroinflammation in brains of adult mice. Journal of Immunotoxicology 14:1, pages 95-102.
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Xiuzhen Fan, Gangduo Wang, Robert D. English & M. Firoze Khan. (2014) Proteomic identification of carbonylated proteins in the kidney of trichloroethene-exposed MRL+/+ mice. Toxicology Mechanisms and Methods 24:1, pages 21-30.
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DeborahE. Keil, MargieM. Peden-Adams, Stacy Wallace, Phillip Ruiz & GaryS. Gilkeson. (2009) Assessment of trichloroethylene (TCE) exposure in murine strains genetically-prone and non-prone to develop autoimmune disease. Journal of Environmental Science and Health, Part A 44:5, pages 443-453.
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. (2009) Letters to the Editor. Journal of Environmental Science and Health, Part A 44:1, pages 116-122.
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Articles from other publishers (22)

Sarah J. Blossom. 2021. Medical Epigenetics. Medical Epigenetics 171 183 .
Sangeeta Khare, Kuppan Gokulan, Katherine Williams, Shasha Bai, Kathleen M. Gilbert & Sarah J. Blossom. (2019) Irreversible effects of trichloroethylene on the gut microbial community and gut-associated immune responses in autoimmune-prone mice. Journal of Applied Toxicology 39:2, pages 209-220.
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Isabelle Marie. (2019) Systemic sclerosis and exposure to heavy metals. Autoimmunity Reviews 18:1, pages 62-72.
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Sarah J. Blossom & Kathleen M. Gilbert. (2018) Epigenetic underpinnings of developmental immunotoxicity and autoimmune disease. Current Opinion in Toxicology 10, pages 23-30.
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Sarah J Blossom, Lorenzo Fernandes, Shasha Bai, Sangeeta Khare, Kuppan Gokulan, Youzhong Yuan, Michael Dewall, Frank A Simmen & Kathleen M Gilbert. (2018) Opposing Actions of Developmental Trichloroethylene and High-Fat Diet Coexposure on Markers of Lipogenesis and Inflammation in Autoimmune-Prone Mice. Toxicological Sciences 164:1, pages 313-327.
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Kathleen M. Gilbert, Shasha Bai, Dustyn Barnette & Sarah J. Blossom. (2017) Exposure Cessation During Adulthood Did Not Prevent Immunotoxicity Caused by Developmental Exposure to Low-Level Trichloroethylene in Drinking Water. Toxicological Sciences 157:2, pages 429-437.
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Sarah J. Blossom, Stepan B. Melnyk, Ming Li, William D. Wessinger & Craig A. Cooney. (2017) Inflammatory and oxidative stress-related effects associated with neurotoxicity are maintained after exclusively prenatal trichloroethylene exposure. NeuroToxicology 59, pages 164-174.
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Yan Jiang, Yufei Dai & Tao Chen. 2017. 51 79 .
Isabelle Marie & Jean-François Gehanno. (2015) Environmental risk factors of systemic sclerosis. Seminars in Immunopathology 37:5, pages 463-473.
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Kathleen M. Gilbert, William Woodruff & Sarah J. Blossom. (2014) Differential Immunotoxicity Induced by Two Different Windows of Developmental Trichloroethylene Exposure. Autoimmune Diseases 2014, pages 1-12.
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Ivan Rusyn, Weihsueh A. Chiu, Lawrence H. Lash, Hans Kromhout, Johnni Hansen & Kathryn Z. Guyton. (2014) Trichloroethylene: Mechanistic, epidemiologic and other supporting evidence of carcinogenic hazard. Pharmacology & Therapeutics 141:1, pages 55-68.
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Sarah J. Blossom. 2014. Trichloroethylene: Toxicity and Health Risks. Trichloroethylene: Toxicity and Health Risks 131 151 .
Kathleen M. Gilbert. 2014. Trichloroethylene: Toxicity and Health Risks. Trichloroethylene: Toxicity and Health Risks 15 35 .
Sarah J. Blossom, Craig A. Cooney, Stepan B. Melnyk, Jenny L. Rau, Christopher J. Swearingen & William D. Wessinger. (2013) Metabolic changes and DNA hypomethylation in cerebellum are associated with behavioral alterations in mice exposed to trichloroethylene postnatally. Toxicology and Applied Pharmacology 269:3, pages 263-269.
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Carolina Barragán-Martínez, Cesar A. Speck-Hernández, Gladis Montoya-Ortiz, Rubén D. Mantilla, Juan-Manuel Anaya & Adriana Rojas-Villarraga. (2012) Organic Solvents as Risk Factor for Autoimmune Diseases: A Systematic Review and Meta-Analysis. PLoS ONE 7:12, pages e51506.
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Sarah J. Blossom, Stepan Melnyk, Craig A. Cooney, Kathleen M. Gilbert & S. Jill James. (2012) Postnatal exposure to trichloroethylene alters glutathione redox homeostasis, methylation potential, and neurotrophin expression in the mouse hippocampus. NeuroToxicology 33:6, pages 1518-1527.
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Dori Germolec, Dwight H. Kono, Jean C. Pfau & K. Michael Pollard. (2012) Animal models used to examine the role of the environment in the development of autoimmune disease: Findings from an NIEHS Expert Panel Workshop. Journal of Autoimmunity 39:4, pages 285-293.
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Craig A. Cooney & Kathleen M. Gilbert. 2012. Toxicology and Epigenetics. Toxicology and Epigenetics 241 260 .
Kathleen M. Gilbert, Ashley R. Nelson, Craig A. Cooney, Brad Reisfeld & Sarah J. Blossom. (2012) Epigenetic Alterations May Regulate Temporary Reversal of CD4+ T Cell Activation Caused by Trichloroethylene Exposure. Toxicological Sciences 127:1, pages 169-178.
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Bethany Winans, Michael C. Humble & B. Paige Lawrence. (2011) Environmental toxicants and the developing immune system: A missing link in the global battle against infectious disease?. Reproductive Toxicology 31:3, pages 327-336.
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K. Michael Pollard, Per Hultman & Dwight H. Kono. (2010) Toxicology of Autoimmune Diseases. Chemical Research in Toxicology 23:3, pages 455-466.
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Rodney R. Dietert, Janice M. Dietert & Jerrie Gavalchin. 2010. Immunotoxicity Testing. Immunotoxicity Testing 39 51 .

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