1,869
Views
38
CrossRef citations to date
0
Altmetric
Research Article

The cytotoxic effects of the organophosphates chlorpyrifos and diazinon differ from their immunomodulating effects

, , , &
Pages 136-145 | Received 06 Feb 2009, Accepted 29 Mar 2009, Published online: 10 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Ahmad Husaini Mohamed, Nur Athirah Noorhisham, Noorfatimah Yahaya, Sharifah Mohamad, Sazlinda Kamaruzzaman, Hasnah Osman & Hassan Y. Aboul-Enein. (2023) Sampling and Sample Preparation Techniques for the Analysis of Organophosphorus Pesticides in Soil Matrices. Critical Reviews in Analytical Chemistry 53:4, pages 906-927.
Read now
Aram Mokarizadeh, Mohammad Reza Faryabi, Mohammad Amin Rezvanfar & Mohammad Abdollahi. (2015) A comprehensive review of pesticides and the immune dysregulation: mechanisms, evidence and consequences. Toxicology Mechanisms and Methods 25:4, pages 258-278.
Read now
D. Luongo, R. Russo, A. Balestrieri, S. Marzocco, P. Bergamo & L. Severino. (2014) In vitro study of AFB1 and AFM1 effects on human lymphoblastoid Jurkat T-cell model. Journal of Immunotoxicology 11:4, pages 353-358.
Read now

Articles from other publishers (35)

Miguel Alfonso Ruiz-Arias, Irma Martha Medina-Díaz, Yael Yvette Bernal-Hernández, Briscia Socorro Barrón-Vivanco, Cyndia Azucena González-Arias, Carlos Alberto Romero-Bañuelos, Francisco Alberto Verdín-Betancourt, José Francisco Herrera-Moreno, Guadalupe Ponce-Vélez, Octavio Gaspar-Ramírez, Pedro de Jesús Bastidas-Bastidas, Fernando Bejarano González & Aurora Elizabeth Rojas-García. (2023) The situation of chlorpyrifos in Mexico: a case study in environmental samples and aquatic organisms. Environmental Geochemistry and Health 45:8, pages 6323-6351.
Crossref
Md Hafiz All Hosen, Alex M. Sykes, Stephen A. Wood, Frederic D. L. Leusch, Deanne J. Whitworth & Susan M. Bengtson Nash. (2023) Novel Use of Cell Profiling Technology to Visualize Mitochondrial Responses of Humpback Whale Fibroblasts to Chemical Exposure. Environmental Science & Technology 57:24, pages 8975-8982.
Crossref
Aleksandra Leska, Adriana Nowak, Justyna Rosicka-Kaczmarek, Małgorzata Ryngajłło & Karolina Henryka Czarnecka-Chrebelska. (2023) Characterization and Protective Properties of Lactic Acid Bacteria Intended to Be Used in Probiotic Preparation for Honeybees (Apis mellifera L.)—An In Vitro Study. Animals 13:6, pages 1059.
Crossref
Elżbieta Wołejko, Bożena Łozowicka, Agata Jabłońska-Trypuć, Marta Pietruszyńska & Urszula Wydro. (2022) Chlorpyrifos Occurrence and Toxicological Risk Assessment: A Review. International Journal of Environmental Research and Public Health 19:19, pages 12209.
Crossref
Frank Glover, Michael L. Eisenberg, Federico Belladelli, Francesco Del Giudice, Tony Chen, Evan Mulloy & W. Michael Caudle. (2022) The association between organophosphate insecticides and blood pressure dysregulation: NHANES 2013–2014. Environmental Health 21:1.
Crossref
Prem Rajak, Abhratanu Ganguly, Saurabh Sarkar, Moutushi Mandi, Moumita Dutta, Sayanti Podder, Salma Khatun & Sumedha Roy. (2021) Immunotoxic role of organophosphates: An unseen risk escalating SARS-CoV-2 pathogenicity. Food and Chemical Toxicology 149, pages 112007.
Crossref
Shweta Thakur, Bibekananda Sarkar, Monisha Dhiman & Anil K. Mantha. (2020) Organophosphate‐pesticides induced survival mechanisms and APE1‐mediated Nrf2 regulation in non‐small‐cell lung cancer cells. Journal of Biochemical and Molecular Toxicology 35:2.
Crossref
Abdullah A. AlKahtane, Esraa Ghanem, Simona G. Bungau, Saud Alarifi, Daoud Ali, Gadah AlBasher, Saad Alkahtani, Lotfi Aleya & Mohamed M. Abdel-Daim. (2020) Carnosic acid alleviates chlorpyrifos-induced oxidative stress and inflammation in mice cerebral and ocular tissues. Environmental Science and Pollution Research 27:11, pages 11663-11670.
Crossref
Magali E. Ridano, Ana C. Racca, Jésica B. Flores-Martín, Luciana Reyna, Susana Genti-Raimondi & Graciela M. Panzetta-Dutari. (2019) Effect of Chlorpyrifos on human extravillous-like trophoblast cells. Reproductive Toxicology 90, pages 118-125.
Crossref
Becky J. Proskocil, Ana Cristina G. Grodzki, David B. Jacoby, Pamela J. Lein & Allison D. Fryer. (2019) Organophosphorus Pesticides Induce Cytokine Release from Differentiated Human THP1 Cells. American Journal of Respiratory Cell and Molecular Biology 61:5, pages 620-630.
Crossref
Arthi Kanthasamy, Huajun Jin, Adhithiya Charli, Anantharam Vellareddy & Anumantha Kanthasamy. (2019) Environmental neurotoxicant-induced dopaminergic neurodegeneration: a potential link to impaired neuroinflammatory mechanisms. Pharmacology & Therapeutics 197, pages 61-82.
Crossref
Carrie Tayour, Beate Ritz, Bryan Langholz, Paul K. Mills, Anna Wu, John P. Wilson, Kaveh Shahabi & Myles Cockburn. (2019) A case–control study of breast cancer risk and ambient exposure to pesticides. Environmental Epidemiology 3:5, pages e070.
Crossref
Asghar Beigi Harchegani, Alireza Rahmani, Eisa Tahmasbpour, Hamid Bakhiari Kabootaraki, Hossein Rostami & Alireza Shahriary. (2018) Mechanisms of diazinon effects on impaired spermatogenesis and male infertility. Toxicology and Industrial Health 34:9, pages 653-664.
Crossref
Xu Zhao, Xiangsheng Hong, Rui Chen, Lilai Yuan, Jinmiao Zha & Jianhui Qin. (2018) New cytokines and TLR pathway signaling molecules in Chinese rare minnow (Gobiocypris rarus): Molecular characterization, basal expression, and their response to chlorpyrifos. Chemosphere 199, pages 26-34.
Crossref
Shweta Thakur, Monisha Dhiman & Anil K. Mantha. (2017) APE1 modulates cellular responses to organophosphate pesticide-induced oxidative damage in non-small cell lung carcinoma A549 cells. Molecular and Cellular Biochemistry 441:1-2, pages 201-216.
Crossref
Guoli Xu, Danqun Huo, Changjun Hou, Yanan Zhao, Jing Bao, Mei Yang & Huanbao Fa. (2018) A regenerative and selective electrochemical aptasensor based on copper oxide nanoflowers-single walled carbon nanotubes nanocomposite for chlorpyrifos detection. Talanta 178, pages 1046-1052.
Crossref
A. Hartwig. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1473 1544 .
Pu Xia, Xiaowei Zhang, Hanxin Zhang, Pingping Wang, Mingming Tian & Hongxia Yu. (2017) Benchmarking Water Quality from Wastewater to Drinking Waters Using Reduced Transcriptome of Human Cells. Environmental Science & Technology 51:16, pages 9318-9326.
Crossref
M.E. Ridano, A.C. Racca, J.B. Flores-Martin, R. Fretes, C.L. Bandeira, L. Reyna, E. Bevilacqua, S. Genti-Raimondi & G.M. Panzetta-Dutari. (2017) Impact of chlorpyrifos on human villous trophoblasts and chorionic villi. Toxicology and Applied Pharmacology 329, pages 26-39.
Crossref
Karla Pozo, Yasna Llanos, Victor H. Estellano, Sandra Cortés, Hector Jorquera, Lorena Gerli, Katerine Pozo, Francisco Encina, Rodrigo Palma & Silvano Focardi. (2016) Occurrence of chlorpyrifos in the atmosphere of the Araucanía Region in Chile using polyurethane foam-based passive air samplers. Atmospheric Pollution Research 7:4, pages 706-710.
Crossref
. 2002. The MAK-Collection for Occupational Health and Safety. The MAK-Collection for Occupational Health and Safety 1 58 .
. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 63 .
Julia Kravchenko, Emanuela Corsini, Marc A. Williams, William Decker, Masoud H. Manjili, Takemi Otsuki, Neetu Singh, Faha Al-Mulla, Rabeah Al-Temaimi, Amedeo Amedei, Anna Maria Colacci, Monica Vaccari, Chiara Mondello, A.Ivana Scovassi, Jayadev Raju, Roslida A. Hamid, Lorenzo Memeo, Stefano Forte, Rabindra Roy, Jordan Woodrick, Hosni K. Salem, Elizabeth P. Ryan, Dustin G. Brown, William H. Bisson, Leroy Lowe & H. Kim Lyerly. (2015) Chemical compounds from anthropogenic environment and immune evasion mechanisms: potential interactions. Carcinogenesis 36:Suppl 1, pages S111-S127.
Crossref
Marina Schäfer, Franziska Koppe, Bernhard Stenger, Christoph Brochhausen, Annette Schmidt, Dirk Steinritz, Horst Thiermann, Charles James Kirkpatrick & Christine Pohl. (2013) Influence of organophosphate poisoning on human dendritic cells. Chemico-Biological Interactions 206:3, pages 472-478.
Crossref
Hans Løkke, Ad M.J. Ragas & Martin Holmstrup. (2013) Tools and perspectives for assessing chemical mixtures and multiple stressors. Toxicology 313:2-3, pages 73-82.
Crossref
Vanina Bulgaroni, Paola Lombardo, Valeria Rivero-Osimani, Berta Vera, Laura Dulgerian, Fabio Cerbán, Virginia Rivero, Gladis Magnarelli & Natalia Guiñazú. (2013) Environmental pesticide exposure modulates cytokines, arginase and ornithine decarboxylase expression in human placenta. Reproductive Toxicology 39, pages 23-32.
Crossref
Kevin Woodward & Kevin WoodwardK. N. Woodward. 2012. Toxicological Effects of Veterinary Medicinal Products in Humans. Toxicological Effects of Veterinary Medicinal Products in Humans 150 243 .
Magali E. Ridano, Ana C. Racca, Jésica Flores-Martín, Soledad A. Camolotto, Gladis Magnarelli de Potas, Susana Genti-Raimondi & Graciela M. Panzetta-Dutari. (2012) Chlorpyrifos modifies the expression of genes involved in human placental function. Reproductive Toxicology 33:3, pages 331-338.
Crossref
Claudia C. Buser, Mieke Jansen, Kevin Pauwels, Luc De Meester & Piet Spaak. (2012) Combined exposure to parasite and pesticide causes increased mortality in the water flea Daphnia. Aquatic Ecology 46:2, pages 261-268.
Crossref
Natalia Guiñazú, Viviana Rena, Susana Genti-Raimondi, Virginia Rivero & Gladis Magnarelli. (2012) Effects of the organophosphate insecticides phosmet and chlorpyrifos on trophoblast JEG-3 cell death, proliferation and inflammatory molecule production. Toxicology in Vitro 26:3, pages 406-413.
Crossref
Michal Cabaj, Róbert Toman, Mária Adamkovičová, Peter Massányi, Branislav Šiška, Norbert Lukáč, Jozef Golian & Sví¤toslav Hluchý. (2012) Quantitative and structural changes of testis and semen quality parameters changes caused by peroral administration of diazinon in rats. Potravinarstvo Slovak Journal of Food Sciences 6:2, pages 9-14.
Crossref
K N Woodward. 2012. Mammalian Toxicology of Insecticides. Mammalian Toxicology of Insecticides 348 426 .
Ana Viñuela, L. Basten Snoek, Joost A. G. Riksen & Jan E. Kammenga. (2010) Genome-Wide Gene Expression Analysis in Response to Organophosphorus Pesticide Chlorpyrifos and Diazinon in C. elegans. PLoS ONE 5:8, pages e12145.
Crossref
Martin Holmstrup, Anne-Mette Bindesbøl, Gertie Janneke Oostingh, Albert Duschl, Volker Scheil, Heinz-R. Köhler, Susana Loureiro, Amadeu M.V.M. Soares, Abel L.G. Ferreira, Cornelia Kienle, Almut Gerhardt, Ryszard Laskowski, Paulina E. Kramarz, Mark Bayley, Claus Svendsen & David J. Spurgeon. (2010) Interactions between effects of environmental chemicals and natural stressors: A review. Science of The Total Environment 408:18, pages 3746-3762.
Crossref
Michal Cabaj, Róbert Toman, Mária Adamkovičová, Peter Massányi, Branislav Šiška, Norbert Lukáč & Jozef Golian. (2010) Structural changes in the rat testis caused by diazinon and selenium. Potravinarstvo Slovak Journal of Food Sciences 4:2, pages 8-16.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.