Safety and efficacy of using heat-killed Lactobacillus plantarum L-137: High-dose and long-term use effects on immune-related safety and intestinal bacterial flora

Hiroko Nakaia Ingredient Research Division, Research and Development Institute, House Wellness Foods Corp, Itami, Japan

Shinji Murosakia Ingredient Research Division, Research and Development Institute, House Wellness Foods Corp, Itami, Japan

Yoshihiro Yamamotoa Ingredient Research Division, Research and Development Institute, House Wellness Foods Corp, Itami, Japan

Michiko Furutanib Wakamatsukawada Clinic, Tokyo, Japan

Rumiko Matsuokab Wakamatsukawada Clinic, Tokyo, Japan

Yoshitaka Hirosea Ingredient Research Division, Research and Development Institute, House Wellness Foods Corp, Itami, JapanCorrespondence[email protected]

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Sérgio Domingos Cardoso Rocha, Peng Lei, Byron Morales-Lange, Liv Torunn Mydland & Margareth Øverland. (2023) From a cell model to a fish trial: Immunomodulatory effects of heat-killed Lactiplantibacillus plantarum as a functional ingredient in aquafeeds for salmonids. Frontiers in Immunology 14.
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Chen Chen, Shucong Fan, Chenhong Shangguan & Jian Zhang. (2022) Evaluation of the effects of simulated in vitro digestion by Gastrodia elata on biological activity and gut microflora regulation. Food Bioscience 50, pages 102147.
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Rieko Yoshitake, Hiroko Nakai, Manato Ebina, Kengo Kawasaki, Shinji Murosaki & Yoshitaka Hirose. (2022) Beneficial Effect of Heat-Killed Lactiplantibacillus plantarum L-137 on Skin Functions in Healthy Participants: A Randomized, Placebo-Controlled, Double-Blind Study. Frontiers in Medicine 9.
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Luís Cláudio Lima De Jesus, Flávia Figueira Aburjaile, Thiago De Jesus Sousa, Andrei Giacchetto Felice, Siomar De Castro Soares, Luiz Carlos Junior Alcantara & Vasco Ariston De Carvalho Azevedo. (2022) Genomic Characterization of Lactobacillus delbrueckii Strains with Probiotics Properties. Frontiers in Bioinformatics 2.
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Wenjie Hu, Xiangyi Kong, Hui Wang, Yunqing Li & Yimin Luo. (2022) Ischemic stroke and intestinal flora: an insight into brain–gut axis. European Journal of Medical Research 27:1.
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Fernanda Alvarenga Lima Barroso, Luís Cláudio Lima de Jesus, Tales Fernando da Silva, Viviane Lima Batista, Juliana Laguna, Nina Dias Coelho-Rocha, Kátia Duarte Vital, Simone Odília Antunes Fernandes, Valbert Nascimento Cardoso, Enio Ferreira, Flaviano Santos Martins, Mariana Martins Drumond, Pamela Mancha-Agresti, Alexander Birbrair, Debmalya Barh & Vasco Azevedo. (2022) Lactobacillus delbrueckii CIDCA 133 Ameliorates Chemotherapy-Induced Mucositis by Modulating Epithelial Barrier and TLR2/4/Myd88/NF-κB Signaling Pathway. Frontiers in Microbiology 13.
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Safety and efficacy of using heat-killed Lactobacillus plantarum L-137: High-dose and long-term use effects on immune-related safety and intestinal bacterial flora

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Safety and efficacy of using heat-killed Lactobacillus plantarum L-137: High-dose and long-term use effects on immune-related safety and intestinal bacterial flora

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