Advanced search
Publication Cover
Autophagy Volume 12, 2016 - Issue 11
Submit an article Journal homepage
2,965
Views
83
CrossRef citations to date
0
Altmetric
Translational Research Paper

Impairment of chaperone-mediated autophagy induces dopaminergic neurodegeneration in rats

Maria XilouriCenter of Clinical Research, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens, Athens, GreeceCorrespondence[email protected] [email protected]
,
Oeystein Roed BrekkCenter of Clinical Research, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens, Athens, Greece;University of Crete, School of Medicine, Heraklion, Crete, Greece
,
Alexia PolissidisCenter of Clinical Research, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens, Athens, Greece
,
Margarita Chrysanthou-PiterouResearch Unit of Histochemistry and Electron Microscopy, 1st Department of Psychiatry, University of Athens Medical School, Eginition Hospital, Athens, Greece
,
Ismini KloukinaCenter of Basic Research, Biomedical Research Foundation of the Academy of Athens, Athens, Greece;Neurobiology Research Institute, Theodor Theohari Cozzika Foundation, Athens, Greece
&
Leonidas StefanisCenter of Clinical Research, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens, Athens, Greece;Second Department of Neurology, National and Kapodistrian University of Athens Medical School, Athens, GreeceCorrespondence[email protected] [email protected]
Pages 2230-2247 | Received 03 Jan 2016, Accepted 14 Jul 2016, Published online: 01 Nov 2016

Citations (83)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (6)

Panagiota Mavroeidi, Fedra Arvanitaki, Maria Vetsi, Stefan Becker, Dimitrios Vlachakis, Poul Henning Jensen, Leonidas Stefanis & Maria Xilouri. (2022) Autophagy mediates the clearance of oligodendroglial SNCA/alpha-synuclein and TPPP/p25A in multiple system atrophy models. Autophagy 18:9, pages 2104-2133.
Read now
S. Joseph Endicott, Alexander C. Monovich, Eric L. Huang, Evelynn I. Henry, Dennis N. Boynton, Logan J. Beckmann, Michael J. MacCoss & Richard A. Miller. (2022) Lysosomal targetomics of ghr KO mice shows chaperone-mediated autophagy degrades nucleocytosolic acetyl-coA enzymes. Autophagy 18:7, pages 1551-1571.
Read now
Jian Li, Mouli Tian, Tong Hua, Haowei Wang, Mei Yang, Wenqian Li, Xiaoping Zhang & Hongbin Yuan. (2021) Combination of autophagy and NFE2L2/NRF2 activation as a treatment approach for neuropathic pain. Autophagy 17:12, pages 4062-4082.
Read now
Solmaz Khalifeh, Fariba Khodagholi, Mohammad-Reza Zarrindast, Rezvan Alizadeh, Sareh Asadi, Hamed Mohammadi Kamsorkh, Mohammad Nasehi, Ali Ghadami & Mitra-Sadat Sadat-Shirazi. (2021) Altered D2 receptor and transcription factor EB expression in offspring of aggressive male rats, along with having depressive and anxiety-like behaviors. International Journal of Neuroscience 131:8, pages 789-799.
Read now
S. Joseph Endicott, Dennis N. Boynton$suffix/text()$suffix/text(), Logan J. Beckmann & Richard A. Miller. (2021) Long-lived mice with reduced growth hormone signaling have a constitutive upregulation of hepatic chaperone-mediated autophagy. Autophagy 17:3, pages 612-625.
Read now
Philip Campbell, Huw Morris & Anthony Schapira. (2018) Chaperone-mediated autophagy as a therapeutic target for Parkinson disease. Expert Opinion on Therapeutic Targets 22:10, pages 823-832.
Read now

Articles from other publishers (77)

Qi Jia, Jin Li, Xiaofeng Guo, Yi Li, You Wu, Yuliang Peng, Zongping Fang & Xijing Zhang. (2024) Neuroprotective effects of chaperone-mediated autophagy in neurodegenerative diseases. Neural Regeneration Research 19:6, pages 1291-1298.
Crossref
Bingyun Li, Yujia Jiang, Ting Wang, Weiwei Liu, Xiaojuan Chen, Jinyi He, Zeyu Du, Ruijiao Yang, Danxiu Miao & Yanshu Li. (2024) MicroRNA-217-5p triggers dopaminergic neuronal degeneration via autophagy activation under Atrazine exposure. Environmental Pollution 340, pages 122811.
Crossref
Zhuo-qing Lan, Zi-yi Ge, Shu-kai Lv, Bing Zhao & Cai-xia Li. (2023) The regulatory role of lipophagy in central nervous system diseases. Cell Death Discovery 9:1.
Crossref
Juan Antonio García-Carmona, Joaquín Amores-Iniesta, José Soler-Usero, María Cerdán-Sánchez, Javier Navarro-Zaragoza, María López-López, Juan José Soria-Torrecillas, Ainhoa Ballesteros-Arenas, José Antonio Pérez-Vicente & Pilar Almela. (2023) Upregulation of Heat-Shock Protein (hsp)-27 in a Patient with Heterozygous SPG11 c.1951C>T and SYNJ1 c.2614G>T Mutations Causing Clinical Spastic Paraplegia. Genes 14:7, pages 1320.
Crossref
Katherine K. Zhang, Peichuan Zhang, Anagha Kodur, Ilkim Erturk, Calvin M. Burns, Cynthia Kenyon, Richard A. Miller & S. Joseph Endicott. (2023) LAMP2A, and other chaperone-mediated autophagy related proteins, do not decline with age in genetically heterogeneous UM-HET3 mice. Aging.
Crossref
Saima Owais & Yasir Hasan Siddique. (2023) A Comprehensive Study of miRNAs in Parkinson’s Disease: Diagnostics and Therapeutic Approaches. CNS & Neurological Disorders - Drug Targets 22:3, pages 353-380.
Crossref
Shuanglong Yi, Linfang Wang, Honglei Wang, Margaret S. Ho & Shiping Zhang. (2022) Pathogenesis of α-Synuclein in Parkinson’s Disease: From a Neuron-Glia Crosstalk Perspective. International Journal of Molecular Sciences 23:23, pages 14753.
Crossref
Alba Navarro-Romero, Irene Fernandez-Gonzalez, Jordi Riera, Marta Montpeyo, Merce Albert-Bayo, Tresa Lopez-Royo, Pablo Castillo-Sanchez, Clara Carnicer-Caceres, Jose Antonio Arranz-Amo, Laura Castillo-Ribelles, Eddie Pradas, Josefina Casas, Miquel Vila & Marta Martinez-Vicente. (2022) Lysosomal lipid alterations caused by glucocerebrosidase deficiency promote lysosomal dysfunction, chaperone-mediated-autophagy deficiency, and alpha-synuclein pathology. npj Parkinson's Disease 8:1.
Crossref
Utibe-Abasi S. Udoh, Pradeep Kumar Rajan, Yuto Nakafuku, Robert Finley & Juan Ramon Sanabria. (2022) Cell Autophagy in NASH and NASH-Related Hepatocellular Carcinoma. International Journal of Molecular Sciences 23:14, pages 7734.
Crossref
Marijn Kuijpers. (2022) Keeping synapses in shape: degradation pathways in the healthy and aging brain. Neuronal Signaling 6:2.
Crossref
Erika Ueda, Tomoko Ohta, Ayumu Konno, Hirokazu Hirai, Yuki Kurauchi, Hiroshi Katsuki & Takahiro Seki. (2022) D-Cysteine Activates Chaperone-Mediated Autophagy in Cerebellar Purkinje Cells via the Generation of Hydrogen Sulfide and Nrf2 Activation. Cells 11:7, pages 1230.
Crossref
Angeleen Fleming, Mathieu Bourdenx, Motoki Fujimaki, Cansu Karabiyik, Gregory J. Krause, Ana Lopez, Adrián Martín-Segura, Claudia Puri, Aurora Scrivo, John Skidmore, Sung Min Son, Eleanna Stamatakou, Lidia Wrobel, Ye Zhu, Ana Maria Cuervo & David C. Rubinsztein. (2022) The different autophagy degradation pathways and neurodegeneration. Neuron 110:6, pages 935-966.
Crossref
Shuangshuang Le, Xin Fu, Maogui Pang, Yao Zhou, Guoqing Yin, Jie Zhang & Daiming Fan. (2022) The Antioxidative Role of Chaperone-Mediated Autophagy as a Downstream Regulator of Oxidative Stress in Human Diseases. Technology in Cancer Research & Treatment 21, pages 153303382211141.
Crossref
Takahiro Seki & Hiroshi Katsuki. 2022. Autophagy in Health and Disease. Autophagy in Health and Disease 385 397 .
Amelina Albornoz, Alvaro Sequeida, Christian Rodríguez & Mauricio Budini. 2022. Autophagy in Health and Disease. Autophagy in Health and Disease 399 412 .
João Duarte Magalhães, Lígia Fão, Rita Vilaça, Sandra Morais Cardoso & Ana Cristina Rego. (2021) Macroautophagy and Mitophagy in Neurodegenerative Disorders: Focus on Therapeutic Interventions. Biomedicines 9:11, pages 1625.
Crossref
Mansour Haidar, Melanie Loix, Jeroen F.J. Bogie & Jerome J.A. Hendriks. (2021) Lipophagy: a new player in CNS disorders. Trends in Endocrinology & Metabolism 32:11, pages 941-951.
Crossref
Yunlan Du, Xiao Yang, Zezhi Li, Weidong Le, Yong Hao, Yeping Song, Fei Wang & Yangtai Guan. (2021) HDAC6-mediated Hsp90 deacetylation reduces aggregation and toxicity of the protein alpha-synuclein by regulating chaperone-mediated autophagy. Neurochemistry International 149, pages 105141.
Crossref
Xiaoyan Xu, Yaqin Sun, Xufeng Cen, Bing Shan, Qingwei Zhao, Tingxue Xie, Zhe Wang, Tingjun Hou, Yu Xue, Mengmeng Zhang, Di Peng, Qiming Sun, Cong Yi, Ayaz Najafov & Hongguang Xia. (2021) Metformin activates chaperone-mediated autophagy and improves disease pathologies in an Alzheimer disease mouse model. Protein & Cell 12:10, pages 769-787.
Crossref
Fan Shi, Dan Luo, Xuexiao Zhou, Qiaozhen Sun, Pei Shen & Shengzhi Wang. (2021) Combined effects of hyperthermia and chemotherapy on the regulate autophagy of oral squamous cell carcinoma cells under a hypoxic microenvironment. Cell Death Discovery 7:1.
Crossref
Panagiota Mavroeidi & Maria Xilouri. (2021) Neurons and Glia Interplay in α-Synucleinopathies. International Journal of Molecular Sciences 22:9, pages 4994.
Crossref
Mathieu Bourdenx, Adrián Martín-Segura, Aurora Scrivo, Jose A. Rodriguez-Navarro, Susmita Kaushik, Inmaculada Tasset, Antonio Diaz, Nadia J. Storm, Qisheng Xin, Yves R. Juste, Erica Stevenson, Enrique Luengo, Cristina C. Clement, Se Joon Choi, Nevan J. Krogan, Eugene V. Mosharov, Laura Santambrogio, Fiona Grueninger, Ludovic Collin, Danielle L. Swaney, David Sulzer, Evripidis Gavathiotis & Ana Maria Cuervo. (2021) Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome. Cell 184:10, pages 2696-2714.e25.
Crossref
Zhaozhong Liao, Bin Wang, Wenjing Liu, Qian Xu, Lin Hou, Jinlian Song, Qingming Guo & Ning Li. (2021) Dysfunction of chaperone-mediated autophagy in human diseases. Molecular and Cellular Biochemistry 476:3, pages 1439-1454.
Crossref
Alexia Polissidis, Maria Koronaiou, Vasia Kollia, Effrosyni Koronaiou, Modestos Nakos‐Bimpos, Marios Bogiongko, Sofia Vrettou, Katerina Karali, Nicolas Casadei, Olaf Riess, Sergio P. Sardi, Maria Xilouri & Leonidas Stefanis. (2020) Psychosis‐Like Behavior and Hyperdopaminergic Dysregulation in Human α ‐Synuclein BAC Transgenic Rats . Movement Disorders 36:3, pages 716-728.
Crossref
Masahiro Sato, Tomoko Ohta, Yuri Morikawa, Ayumu Konno, Hirokazu Hirai, Yuki Kurauchi, Akinori Hisatsune, Hiroshi Katsuki & Takahiro Seki. (2020) Ataxic phenotype and neurodegeneration are triggered by the impairment of chaperone‐mediated autophagy in cerebellar neurons. Neuropathology and Applied Neurobiology 47:2, pages 198-209.
Crossref
Joanna Kowalczyk, Modestos Nakos-Bimpos, Alexia Polissidis, Christina Dalla, Nikolaos Kokras, Krystyna Skalicka-Wozniak & Barbara Budzynska. (2021) Xanthotoxin affects depression-related behavior and neurotransmitters content in a sex-dependent manner in mice. Behavioural Brain Research 399, pages 112985.
Crossref
Jaione Auzmendi-Iriarte & Ander Matheu. (2021) Impact of Chaperone-Mediated Autophagy in Brain Aging: Neurodegenerative Diseases and Glioblastoma. Frontiers in Aging Neuroscience 12.
Crossref
S. Joseph Endicott, Zachary J. Ziemba, Logan J. Beckmann, Dennis N. BoyntonJr.Jr. & Richard A. Miller. (2020) Inhibition of class I PI3K enhances chaperone-mediated autophagy. Journal of Cell Biology 219:12.
Crossref
Mary Xylaki, Ioanna Boumpoureka, Maroula G. Kokotou, Theodoros Marras, Georgia Papadimitriou, Ismini Kloukina, Victoria Magrioti, George Kokotos, Kostas Vekrellis & Evangelia Emmanouilidou. (2020) Changes in the cellular fatty acid profile drive the proteasomal degradation of α‐synuclein and enhance neuronal survival. The FASEB Journal 34:11, pages 15123-15145.
Crossref
Yeru Chen, Piao Zhang, Xianyi Lin, Huan Zhang, Jiamin Miao, Youfa Zhou & Gang Chen. (2020) Mitophagy impairment is involved in sevoflurane-induced cognitive dysfunction in aged rats. Aging 12:17, pages 17235-17256.
Crossref
Maria Fouka, Panagiota Mavroeidi, Grigoria Tsaka & Maria Xilouri. (2020) In Search of Effective Treatments Targeting α-Synuclein Toxicity in Synucleinopathies: Pros and Cons. Frontiers in Cell and Developmental Biology 8.
Crossref
Neha Joshi, Atchaya Raveendran & Shirisha Nagotu. (2020) Chaperones and Proteostasis: Role in Parkinson’s Disease. Diseases 8:2, pages 24.
Crossref
Inês Caldeira Brás, Antonio Dominguez‐Meijide, Ellen Gerhardt, David Koss, Diana F. Lázaro, Patrícia I. Santos, Eftychia Vasili, Mary Xylaki & Tiago Fleming Outeiro. (2020) Synucleinopathies: Where we are and where we need to go. Journal of Neurochemistry 153:4, pages 433-454.
Crossref
Kun Wang, Shengjia Peng, Shaofeng Xiong, Ailin Niu, Min Xia, Xiaowei Xiong, Guohua Zeng & Qiren Huang. (2020) Naringin inhibits autophagy mediated by PI3K-Akt-mTOR pathway to ameliorate endothelial cell dysfunction induced by high glucose/high fat stress. European Journal of Pharmacology 874, pages 173003.
Crossref
Thomas Nury, Gérard Lizard & Anne Vejux. (2020) Lipids Nutrients in Parkinson and Alzheimer’s Diseases: Cell Death and Cytoprotection. International Journal of Molecular Sciences 21:7, pages 2501.
Crossref
Eduardo P. De Mattos, Anne Wentink, Carmen Nussbaum-Krammer, Christian Hansen, Steven Bergink, Ronald Melki & Harm H. Kampinga. (2020) Protein Quality Control Pathways at the Crossroad of Synucleinopathies. Journal of Parkinson's Disease 10:2, pages 369-382.
Crossref
Xu Hou, Jens O. Watzlawik, Fabienne C. Fiesel & Wolfdieter Springer. (2020) Autophagy in Parkinson's Disease. Journal of Molecular Biology 432:8, pages 2651-2672.
Crossref
Ying Yang & Daniel J. Klionsky. (2020) Autophagy and disease: unanswered questions. Cell Death & Differentiation 27:3, pages 858-871.
Crossref
Federica Albanese, Salvatore Novello & Michele Morari. (2019) Autophagy and LRRK2 in the Aging Brain. Frontiers in Neuroscience 13.
Crossref
Yanan Zhang, Dawei Liu, Haijuan Hu, Puqiang Zhang, Ruiqin Xie & Wei Cui. (2019) HIF-1α/BNIP3 signaling pathway-induced-autophagy plays protective role during myocardial ischemia-reperfusion injury. Biomedicine & Pharmacotherapy 120, pages 109464.
Crossref
Guillaume Robert, Arnaud Jacquel & Patrick Auberger. (2019) Chaperone-Mediated Autophagy and Its Emerging Role in Hematological Malignancies. Cells 8:10, pages 1260.
Crossref
Silvia Cerri & Fabio Blandini. (2019) Role of Autophagy in Parkinson’s Disease. Current Medicinal Chemistry 26:20, pages 3702-3718.
Crossref
Leonidas Stefanis, Evangelia Emmanouilidou, Marina Pantazopoulou, Deniz Kirik, Kostas Vekrellis & George K. Tofaris. (2019) How is alpha‐synuclein cleared from the cell?. Journal of Neurochemistry 150:5, pages 577-590.
Crossref
Shouping Xu, Shiyao Sui, Xianyu Zhang, Boran Pang, Lin Wan & Da Pang. (2019) Modulation of autophagy in human diseases strategies to foster strengths and circumvent weaknesses. Medicinal Research Reviews 39:5, pages 1953-1999.
Crossref
Brian Spencer, Ivy Trinh, Edward Rockenstein, Michael Mante, Jazmin Florio, Anthony Adame, Omar M.A. El-Agnaf, Changyoun Kim, Eliezer Masliah & Robert A. Rissman. (2019) Systemic peptide mediated delivery of an siRNA targeting α-syn in the CNS ameliorates the neurodegenerative process in a transgenic model of Lewy body disease. Neurobiology of Disease 127, pages 163-177.
Crossref
Wesley Peng, Georgia Minakaki, Maria Nguyen & Dimitri Krainc. (2019) Preserving Lysosomal Function in the Aging Brain: Insights from Neurodegeneration. Neurotherapeutics 16:3, pages 611-634.
Crossref
Tiago Fleming Outeiro, Kirsten Harvey, Antonio Dominguez-Meijide & Ellen Gerhardt. (2019) LRRK2, alpha-synuclein, and tau: partners in crime or unfortunate bystanders?. Biochemical Society Transactions 47:3, pages 827-838.
Crossref
Marie-Laure Arotcarena, Margaux Teil & Benjamin Dehay. (2019) Autophagy in Synucleinopathy: The Overwhelmed and Defective Machinery. Cells 8:6, pages 565.
Crossref
Liang Zhao & Zhiqin Wang. (2019) MicroRNAs: Game Changers in the Regulation of α -Synuclein in Parkinson’s Disease . Parkinson's Disease 2019, pages 1-10.
Crossref
Reiho Tsutsumi, Yuria Hori, Takahiro Seki, Yuki Kurauchi, Masahiro Sato, Mutsumi Oshima, Akinori Hisatsune & Hiroshi Katsuki. (2019) Involvement of exosomes in dopaminergic neurodegeneration by microglial activation in midbrain slice cultures. Biochemical and Biophysical Research Communications 511:2, pages 427-433.
Crossref
Oeystein Roed Brekk, Manousos Makridakis, Panagiota Mavroeidi, Antonia Vlahou, Maria Xilouri & Leonidas Stefanis. (2019) Impairment of chaperone-mediated autophagy affects neuronal homeostasis through altered expression of DJ-1 and CRMP-2 proteins. Molecular and Cellular Neuroscience 95, pages 1-12.
Crossref
Noémie Cresto, Camille Gardier, Francesco Gubinelli, Marie-Claude Gaillard, Géraldine Liot, Andrew B. West & Emmanuel Brouillet. (2019) The unlikely partnership between LRRK2 and α-synuclein in Parkinson's disease. European Journal of Neuroscience 49:3, pages 339-363.
Crossref
Iván E. Alfaro, Amelina Albornoz, Alfredo Molina, José Moreno, Karina Cordero, Alfredo Criollo & Mauricio Budini. (2019) Chaperone Mediated Autophagy in the Crosstalk of Neurodegenerative Diseases and Metabolic Disorders. Frontiers in Endocrinology 9.
Crossref
Manish Kumar Tripathi, Charul Rajput, Saumya Mishra, Mohd Sami ur Rasheed & Mahendra Pratap Singh. (2018) Malfunctioning of Chaperone-Mediated Autophagy in Parkinson’s Disease: Feats, Constraints, and Flaws of Modulators. Neurotoxicity Research 35:1, pages 260-270.
Crossref
Guoxin Zhang, Yun Xia, Fang Wan, Kai Ma, Xingfang Guo, Liang Kou, Sijia Yin, Chao Han, Ling Liu, Jinsha Huang, Nian Xiong & Tao Wang. (2018) New Perspectives on Roles of Alpha-Synuclein in Parkinson’s Disease. Frontiers in Aging Neuroscience 10.
Crossref
Jia-qing Yan, Yu-he Yuan, Shi-feng Chu, Guo-hui Li & Nai-hong Chen. (2018) E46K Mutant α-Synuclein Is Degraded by Both Proteasome and Macroautophagy Pathway. Molecules 23:11, pages 2839.
Crossref
Baris Bingol. (2018) Autophagy and lysosomal pathways in nervous system disorders. Molecular and Cellular Neuroscience 91, pages 167-208.
Crossref
Susmita Kaushik & Ana Maria Cuervo. (2018) The coming of age of chaperone-mediated autophagy. Nature Reviews Molecular Cell Biology 19:6, pages 365-381.
Crossref
Wenming Li, Juan Dou, Jing Yang, Haidong Xu & Hua She. (2018) Targeting Chaperone-Mediated Autophagy for Disease Therapy. Current Pharmacology Reports 4:3, pages 261-275.
Crossref
Xian-Si Zeng, Wen-Shuo Geng, Jin-Jing Jia, Lei Chen & Peng-Peng Zhang. (2018) Cellular and Molecular Basis of Neurodegeneration in Parkinson Disease. Frontiers in Aging Neuroscience 10.
Crossref
Xiaohong Wang, Lei Pang, Yanqing Zhang, Jiang Xu, Dongyi Ding, Tianli Yang, Qian Zhao, Fan Wu, Fei Li, Haiwei Meng & Duonan Yu. (2018) Lycium barbarum Polysaccharide Promotes Nigrostriatal Dopamine Function by Modulating PTEN/AKT/mTOR Pathway in a Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) Murine Model of Parkinson’s Disease. Neurochemical Research 43:4, pages 938-947.
Crossref
Yong chul Jang, Dong Joo Hwang, Jung Hoon Koo, Hyun Seob Um, Nam Hee Lee, Dong Cheol Yeom, Youngil Lee & Joon Yong Cho. (2018) Association of exercise-induced autophagy upregulation and apoptosis suppression with neuroprotection against pharmacologically induced Parkinson's disease. Journal of Exercise Nutrition & Biochemistry 22:1, pages 1-8.
Crossref
Vassilis E Papadopoulos, Georgia Nikolopoulou, Ivi Antoniadou, Antonia Karachaliou, Giovanna Arianoglou, Evangelia Emmanouilidou, S Pablo Sardi, Leonidas Stefanis & Kostas Vekrellis. (2018) Modulation of β-glucocerebrosidase increases α-synuclein secretion and exosome release in mouse models of Parkinson’s disease. Human Molecular Genetics.
Crossref
Emily M. Rocha, Briana De Miranda & Laurie H. Sanders. (2018) Alpha-synuclein: Pathology, mitochondrial dysfunction and neuroinflammation in Parkinson’s disease. Neurobiology of Disease 109, pages 249-257.
Crossref
Daniel Moreno-Blas, Elisa Gorostieta-Salas & Susana Castro-Obregón. (2018) Connecting chaperone-mediated autophagy dysfunction to cellular senescence. Ageing Research Reviews 41, pages 34-41.
Crossref
Esther Wong. 2018. Conn's Handbook of Models for Human Aging. Conn's Handbook of Models for Human Aging 1117 1132 .
Steve Catarino, Paulo Pereira & Henrique Girão. (2017) Molecular control of chaperone-mediated autophagy. Essays in Biochemistry 61:6, pages 663-674.
Crossref
Daniel Kam Yin Chan, Ying Hua Xu, Luke Kar Man Chan, Nady Braidy & George D. Mellick. (2017) Mini-review on initiatives to interfere with the propagation and clearance of alpha-synuclein in Parkinson’s disease. Translational Neurodegeneration 6:1.
Crossref
Xueyan Liang, Yufang Yang, Zhenguang Huang, Jinling Zhou, Yue’e Li & Xiaobin Zhong. (2017) Panax notoginseng saponins mitigate cisplatin induced nephrotoxicity by inducing mitophagy via HIF-1α . Oncotarget 8:61, pages 102989-103003.
Crossref
Nard Kubben & Tom Misteli. (2017) Shared molecular and cellular mechanisms of premature ageing and ageing-associated diseases. Nature Reviews Molecular Cell Biology 18:10, pages 595-609.
Crossref
Destiny-Love Manecka, Benoît Vanderperre, Edward A. Fon & Thomas M. Durcan. (2017) The Neuroprotective Role of Protein Quality Control in Halting the Development of Alpha-Synuclein Pathology. Frontiers in Molecular Neuroscience 10.
Crossref
Ben Loos, Daniel J. Klionsky & Esther Wong. (2017) Augmenting brain metabolism to increase macro- and chaperone-mediated autophagy for decreasing neuronal proteotoxicity and aging. Progress in Neurobiology 156, pages 90-106.
Crossref
Sylviane Muller, Susana Brun, Frédérique René, Jérôme de Sèze, Jean-Philippe Loeffler & Hélène Jeltsch-David. (2017) Autophagy in neuroinflammatory diseases. Autoimmunity Reviews 16:8, pages 856-874.
Crossref
Lorenzo Galluzzi, José Manuel Bravo-San Pedro, Beth Levine, Douglas R. Green & Guido Kroemer. (2017) Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles. Nature Reviews Drug Discovery 16:7, pages 487-511.
Crossref
Maria Karamita, Christopher Barnum, Wiebke Möbius, Malú G. Tansey, David E. Szymkowski, Hans Lassmann & Lesley Probert. (2017) Therapeutic inhibition of soluble brain TNF promotes remyelination by increasing myelin phagocytosis by microglia. JCI Insight 2:8.
Crossref
Gessica Sala, Daniele Marinig, Alessandro Arosio & Carlo Ferrarese. (2016) Role of Chaperone-Mediated Autophagy Dysfunctions in the Pathogenesis of Parkinson’s Disease. Frontiers in Molecular Neuroscience 9.
Crossref
Maria Xilouri & Leonidas Stefanis. (2016) Chaperone mediated autophagy in aging: Starve to prosper. Ageing Research Reviews 32, pages 13-21.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.