3,604
Views
29
CrossRef citations to date
0
Altmetric
Research Paper - Translational

HMGB1 represses the anti-cancer activity of sunitinib by governing TP53 autophagic degradation via its nucleus-to-cytoplasm transport

, , , , , , , & show all
Pages 2155-2170 | Received 05 Sep 2017, Accepted 10 Jul 2018, Published online: 11 Sep 2018

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (1)

Zhifei Xu, Ying Jin, Zizheng Gao, Yan Zeng, Jiangxia Du, Hao Yan, Xueqin Chen, Li Ping, Nengming Lin, Bo Yang, Qiaojun He & Peihua Luo. (2022) Autophagic degradation of CCN2 (cellular communication network factor 2) causes cardiotoxicity of sunitinib. Autophagy 18:5, pages 1152-1173.
Read now

Articles from other publishers (28)

Yunxia Wang, Xiaolin Liu, Luyao Gong, Weihong Ding, Wenjing Hao, Yeheng Peng, Jun Zhang, Weimin Cai & Yuan Gao. (2023) Mechanisms of sunitinib resistance in renal cell carcinoma and associated opportunities for therapeutics. British Journal of Pharmacology 180:23, pages 2937-2955.
Crossref
Long Liu, Yi Feng, Chunguang Guo, Siyuan Weng, Hui Xu, Zhe Xing, Yuyuan Zhang, Libo Wang & Xinwei Han. (2023) Multi-center validation of an immune-related lncRNA signature for predicting survival and immune status of patients with renal cell carcinoma: an integrating machine learning-derived study. Journal of Cancer Research and Clinical Oncology 149:13, pages 12115-12129.
Crossref
Qingfu Su, Zhenliang Pan, Heyi Chen, Jiabi Chen, Yanmei Zhang & Wei Zhuang. (2023) RBM47 restrains renal cell carcinoma progression and chemoresistance through interacting with lncRNA HOXB-AS1. Cell Death Discovery 9:1.
Crossref
Ruochan ChenJu ZouRui KangDaolin Tang. (2023) The Redox Protein High-Mobility Group Box 1 in Cell Death and Cancer. Antioxidants & Redox Signaling 39:7-9, pages 569-590.
Crossref
Li-Hua Shao, Li Zhu, Meng Wang, Yue Ning, Feng-Qin Chen, Xia-Qing Gao, Chun-Ting Yang, Hong-Wei Wang & Hai-Long Li. (2023) Mechanisms involved in the HMGB1 modulation of tumor multidrug resistance (Review). International Journal of Molecular Medicine 52:2.
Crossref
Hao Yan, Wentong Wu, Yuhuai Hu, Jinjin Li, Jiangxin Xu, Xueqin Chen, Zhifei Xu, Xiaochun Yang, Bo Yang, Qiaojun He & Peihua Luo. (2023) Regorafenib inhibits EphA2 phosphorylation and leads to liver damage via the ERK/MDM2/p53 axis. Nature Communications 14:1.
Crossref
Zhuang Li, Wen-Juan Fu, Xiao-Qing Chen, Shuai Wang, Ru-Song Deng, Xiao-Peng Tang, Kai-Di Yang, Qin Niu, Hong Zhou, Qing-Rui Li, Yong Lin, Mei Liang, Si-Si Li, Yi-Fang Ping, Xin-Dong Liu, Xiu-Wu Bian & Xiao-Hong Yao. (2022) Autophagy-based unconventional secretion of HMGB1 in glioblastoma promotes chemosensitivity to temozolomide through macrophage M1-like polarization. Journal of Experimental & Clinical Cancer Research 41:1.
Crossref
Xueyuan Zhang, Naiyi Zou, Wenzhao Deng, Chunyang Song, Ke Yan, Wenbin Shen & Shuchai Zhu. (2022) HMGB1 induces radioresistance through PI3K/AKT/ATM pathway in esophageal squamous cell carcinoma. Molecular Biology Reports 49:12, pages 11933-11945.
Crossref
Giulia D. S. Ferretti, Julia Quarti, Gileno dos Santos, Luciana P. Rangel & Jerson L. Silva. (2022) Anticancer Therapeutic Strategies Targeting p53 Aggregation. International Journal of Molecular Sciences 23:19, pages 11023.
Crossref
Maohua Huang, Yuning Lin, Chenran Wang, Lijuan Deng, Minfeng Chen, Yehuda G. Assaraf, Zhe-Sheng Chen, Wencai Ye & Dongmei Zhang. (2022) New insights into antiangiogenic therapy resistance in cancer: Mechanisms and therapeutic aspects. Drug Resistance Updates 64, pages 100849.
Crossref
Fanen Yuan, Qian Sun, Si Zhang, Liguo Ye, Yang Xu, Gang Deng, Zhou Xu, Shenqi Zhang, Baohui Liu & Qianxue Chen. (2022) The dual role of p62 in ferroptosis of glioblastoma according to p53 status. Cell & Bioscience 12:1.
Crossref
Ruochan Chen, Rui Kang & Daolin Tang. (2022) The mechanism of HMGB1 secretion and release. Experimental & Molecular Medicine 54:2, pages 91-102.
Crossref
Md Ataur Rahman, Moon Nyeo Park, MD Hasanur Rahman, Md Mamunur Rashid, Rokibul Islam, Md Jamal Uddin, Md Abdul Hannan & Bonglee Kim. (2022) p53 Modulation of Autophagy Signaling in Cancer Therapies: Perspectives Mechanism and Therapeutic Targets. Frontiers in Cell and Developmental Biology 10.
Crossref
DoaaA Ibrahim & DoaaI Abdelrahman. (2022) Evaluation of RUNX2 and HMGB1 expression as markers of tumor aggressiveness in urothelial carcinoma. Egyptian Journal of Pathology 42:1, pages 37.
Crossref
Ying Jin, Xueqin Chen, Zizheng Gao, Xiaofei Shen, Huangxi Fu, Zezheng Pan, Hao Yan, Bo Yang, Qiaojun He, Zhifei Xu & Peihua Luo. (2021) Bisdemethoxycurcumin alleviates vandetanib-induced cutaneous toxicity in vivo and in vitro through autophagy activation. Biomedicine & Pharmacotherapy 144, pages 112297.
Crossref
Asmita Banstola, Kishwor Poudel, Jong Oh Kim, Jee-Heon Jeong & Simmyung Yook. (2021) Recent progress in stimuli-responsive nanosystems for inducing immunogenic cell death. Journal of Controlled Release 337, pages 505-520.
Crossref
Zhiwei Liao, Suyun Li, Rong Liu, Xiaobo Feng, Yunsong Shi, Kun Wang, Shuai Li, Yukun Zhang, Xinghuo Wu & Cao Yang. (2021) Autophagic Degradation of Gasdermin D Protects against Nucleus Pulposus Cell Pyroptosis and Retards Intervertebral Disc Degeneration In Vivo. Oxidative Medicine and Cellular Longevity 2021, pages 1-22.
Crossref
Jingwen Xu, Yi Wang, Zhe Wang, Yihai Wang & Xiangjiu He. (2021) T-17, a spirostanol saponin, inhibits p53-independent proliferation and p53-dependent migration of gastric cancer cells. Steroids 170, pages 108828.
Crossref
Hai Wang, Dan-Qing Hu, Qiao Xiao, Yi-Bo Liu, Jia Song, Yuxia Liang, Jian-Wen Ruan, Zhe-Zheng Wang, Jing-Xian Li, Li Pan, Meng-Chen Wang, Ming Zeng, Li-Li Shi, Kai Xu, Qin Ning, Guohua Zhen, Di Yu, De-Yun Wang, Sally E. Wenzel & Zheng Liu. (2021) Defective STING expression potentiates IL-13 signaling in epithelial cells in eosinophilic chronic rhinosinusitis with nasal polyps. Journal of Allergy and Clinical Immunology 147:5, pages 1692-1703.
Crossref
Chunxiang Zhou & Qun Yang. (2021) Value of HMGB1 expression for assessing gastric cancer severity: a systematic meta-analysis. Journal of International Medical Research 49:3, pages 030006052199331.
Crossref
Zhifei Xu, Wentong Wu, Hao Yan, Yuhuai Hu, Qiaojun He & Peihua Luo. (2021) Regulation of p53 stability as a therapeutic strategy for cancer. Biochemical Pharmacology 185, pages 114407.
Crossref
Yongchang Lai, Fucai Tang, Yapeng Huang, Chengwu He, Chiheng Chen, Jiquan Zhao, Wenqi Wu & Zhaohui He. (2020) The tumour microenvironment and metabolism in renal cell carcinoma targeted or immune therapy. Journal of Cellular Physiology 236:3, pages 1616-1627.
Crossref
Mourad Zerfaoui, Titilope Modupe Dokunmu, Eman Ali Toraih, Bashir M. Rezk, Zakaria Y. Abd Elmageed & Emad Kandil. (2021) New Insights into the Link between Melanoma and Thyroid Cancer: Role of Nucleocytoplasmic Trafficking. Cells 10:2, pages 367.
Crossref
Yong Shi, Erik Norberg & Helin Vakifahmetoglu-Norberg. (2021) Mutant p53 as a Regulator and Target of Autophagy. Frontiers in Oncology 10.
Crossref
Hyunwoo Chung, Hyunsung Nam, Thuy Nguyen-Phuong, Jiyun Jang, Sung Ji Hong, So Won Choi, Seung Bum Park & Chung-Gyu Park. (2021) The blockade of cytoplasmic HMGB1 modulates the autophagy/apoptosis checkpoint in stressed islet beta cells. Biochemical and Biophysical Research Communications 534, pages 1053-1058.
Crossref
Hui Li, Xinwei Kuang, Long Liang, Youqiong Ye, YongChang Zhang, Jialu Li, Fangyu Ma, Juan Tao, Guang Lei, Shuang Zhao, Juan Su, Nong Yang, Cong Peng, Xiaowei Xu, Mien‐Chie Hung, Leng Han, Hong Liu, Jing Liu & Xiang Chen. (2020) The Beneficial Role of Sunitinib in Tumor Immune Surveillance by Regulating Tumor PD‐L1. Advanced Science 8:2.
Crossref
Carolina M. Gorgulho, Graziela G. Romagnoli, Rosh Bharthi & Michael T. Lotze. (2019) Johnny on the Spot-Chronic Inflammation Is Driven by HMGB1. Frontiers in Immunology 10.
Crossref
Kohji Yamada & Kiyotsugu Yoshida. (2019) Mechanical insights into the regulation of programmed cell death by p53 via mitochondria. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1866:5, pages 839-848.
Crossref