Advanced search
Publication Cover
Autophagy Volume 16, 2020 - Issue 1
Submit an article Journal homepage
4,244
Views
23
CrossRef citations to date
0
Altmetric
Research Paper

Dual roles of ULK1 (unc-51 like autophagy activating kinase 1) in cytoprotection against lipotoxicity

Jeong Su ParkSeverance Biomedical Science Institute, Yonsei Biomedical Research Institute, Yonsei University College of Medicine, Seoul, Republic of KoreaView further author information
,
Da Hyun LeeSeverance Biomedical Science Institute, Yonsei Biomedical Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea;Brain Korea 21 PLUS Project for Medical Science, Yonsei University, Seoul, Republic of KoreaView further author information
,
Yu Seol LeeSeverance Biomedical Science Institute, Yonsei Biomedical Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea;Brain Korea 21 PLUS Project for Medical Science, Yonsei University, Seoul, Republic of KoreaView further author information
,
Eunji OhBrain Korea 21 PLUS Project for Medical Science, Yonsei University, Seoul, Republic of KoreaView further author information
,
Kwang-Hee BaeMetabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, KoreaORCID Iconhttps://orcid.org/0000-0002-5868-2556View further author information
ORCID Icon,
Kyoung-Jin OhMetabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, KoreaORCID Iconhttps://orcid.org/0000-0002-2224-7202View further author information
ORCID Icon,
Hyunmi KimMetabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, KoreaView further author information
&
Soo Han BaeSeverance Biomedical Science Institute, Yonsei Biomedical Research Institute, Yonsei University College of Medicine, Seoul, Republic of KoreaCorrespondence[email protected]
View further author information
 show all
Pages 86-105 | Received 27 Mar 2018, Accepted 15 Mar 2019, Published online: 09 Apr 2019

Citations (23)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Jia-Ni Shang, Chen-Ge Yu, Rui Li, Yan Xi, Yue Jenny Jian, Nan Xu & Su Chen. (2023) The nonautophagic functions of autophagy-related proteins. Autophagy 0:0, pages 1-15.
Read now
Shengjie Liao, Mi Huang, Yanli Liao & Chao Yuan. (2023) HMOX1 Promotes Ferroptosis Induced by Erastin in Lens Epithelial Cell through Modulates Fe2+ Production. Current Eye Research 48:1, pages 25-33.
Read now

Articles from other publishers (21)

Bin Lee, Young Hun Kim, Woori Lee, Hee Youn Choi, Jisun Lee, Jiwon Kim, Dương Ngọc Mai, Su Ful Jung, Man Sup Kwak & Jeon-Soo Shin. (2023) USP13 deubiquitinates p62/SQSTM1 to induce autophagy and Nrf2 release for activating antioxidant response genes. Free Radical Biology and Medicine 208, pages 820-832.
Crossref
Rohit Anthony Sinha. (2023) Autophagy: A Cellular Guardian against Hepatic Lipotoxicity. Genes 14:3, pages 553.
Crossref
Xinyue Sun, Wenyue Zhang, Yuqi Wang, Yilei Zhang, Xiaojing Liu, Xu Shi & Shiwen Xu. (2023) Combined exposure to di(2-ethylhexyl) phthalate and polystyrene microplastics induced renal autophagy through the ROS/AMPK/ULK1 pathway. Food and Chemical Toxicology 171, pages 113521.
Crossref
Yicheng Zhou, Zhangwang Li, Minxuan Xu, Deju Zhang, Jitao Ling, Peng Yu & Yunfeng Shen. (2022) O-GlycNacylation Remission Retards the Progression of Non-Alcoholic Fatty Liver Disease. Cells 11:22, pages 3637.
Crossref
Madhulika Tripathi, Brijesh Kumar Singh, Jin Zhou, Keziah Tikno, Anissa Widjaja, Reddemma Sandireddy, Kabilesh Arul, Siti Aishah Binte Abdul Ghani, George Goh Boon Bee, Kiraely Adam Wong, Ho Jia Pei, Shamini Guna Shekeran, Rohit Anthony Sinha, Manvendra K. Singh, Stuart Alexander Cook, Ayako Suzuki, Teegan Reina Lim, Chang-Chuen Cheah, Jue Wang, Rui-Ping Xiao, Xiuqing Zhang, Pierce Kah Hoe Chow & Paul Michael Yen. (2022) Vitamin B12 and folate decrease inflammation and fibrosis in NASH by preventing syntaxin 17 homocysteinylation. Journal of Hepatology 77:5, pages 1246-1255.
Crossref
Ke Zhang, Duoduo Zhang, Junqiao Wang, Yuting Wang, Jiarui Hu, Yujia Zhou, Xingtao Zhou, Shaoping Nie & Mingyong Xie. (2022) Aloe gel glucomannan induced colon cancer cell death via mitochondrial damage-driven PINK1/Parkin mitophagy pathway. Carbohydrate Polymers 295, pages 119841.
Crossref
Ze Rong, Kaifeng Zheng, Jun Chen & Xiaofeng Jin. (2022) Function and regulation of ULK1: From physiology to pathology. Gene 840, pages 146772.
Crossref
Feilong Chen, Mei Xiao, Jing Feng, Reziyamu Wufur, Keli Liu, Shaofan Hu & Yiguo Zhang. (2022) Different Inhibition of Nrf2 by Two Keap1 Isoforms α and β to Shape Malignant Behaviour of Human Hepatocellular Carcinoma. International Journal of Molecular Sciences 23:18, pages 10342.
Crossref
Danlei Li, Wenhu Pi, Zhenzhu Sun, Xiaoman Liu & Jianjun Jiang. (2022) Ferroptosis and its role in cardiomyopathy. Biomedicine & Pharmacotherapy 153, pages 113279.
Crossref
Bunty Sharma, Deeksha Pal, Ujjawal Sharma & Aman Kumar. (2022) Mitophagy: An Emergence of New Player in Alzheimer’s Disease. Frontiers in Molecular Neuroscience 15.
Crossref
Yangyang Wang, Yipei Ding, Pengbo Sun, Wanqiu Zhang, Qilei Xin, Ningchao Wang, Yaoyun Niu, Yang Chen, Jingyi Luo, Jinghua Lu, Jin Zhou, Naihan Xu, Yaou Zhang & Weidong Xie. (2022) Empagliflozin-Enhanced Antioxidant Defense Attenuates Lipotoxicity and Protects Hepatocytes by Promoting FoxO3a- and Nrf2-Mediated Nuclear Translocation via the CAMKK2/AMPK Pathway. Antioxidants 11:5, pages 799.
Crossref
Da Hyun Lee, Jeong Su Park, Yu Seol Lee & Soo Han Bae. (2022) PERK prevents hepatic lipotoxicity by activating the p62-ULK1 axis-mediated noncanonical KEAP1-Nrf2 pathway. Redox Biology 50, pages 102235.
Crossref
Sangam Rajak, Sana Raza & Rohit Anthony Sinha. (2022) ULK1 Signaling in the Liver: Autophagy Dependent and Independent Actions. Frontiers in Cell and Developmental Biology 10.
Crossref
Sang Hyun Seo, Da Hyun Lee, Yu Seol Lee, Kyung Joo Cho, Hye Jung Park, Hye Won Lee, Beom Kyung Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Soo Han Bae & Seung Up Kim. (2022) Co-administration of ursodeoxycholic acid with rosuvastatin/ezetimibe in a non-alcoholic fatty liver disease model. Gastroenterology Report 10.
Crossref
Xialin Yan, Zile Shen, Dingye Yu, Chongke Zhao, Hongbo Zou, Bingwei Ma, Wenxi Dong, Wenhao Chen, Dongdong Huang & Zhen Yu. (2022) Nrf2 contributes to the benefits of exercise interventions on age-related skeletal muscle disorder via regulating Drp1 stability and mitochondrial fission. Free Radical Biology and Medicine 178, pages 59-75.
Crossref
Ruiyun Wu, Pinglan Li, Yi Wang, Nan Su, Mengyuan Xiao, Xiaojun Li & Nan Shang. (2022) Structural analysis and anti-cancer activity of low-molecular-weight chondroitin sulfate from hybrid sturgeon cartilage. Carbohydrate Polymers 275, pages 118700.
Crossref
Peter M. Abuja, Kurt Zatloukal & Helmut Denk. (2021) Priming, Triggering, Adaptation and Senescence (PTAS): A Hypothesis for a Common Damage Mechanism of Steatohepatitis. International Journal of Molecular Sciences 22:22, pages 12545.
Crossref
Kai Chen, Chen Su, Wensi Tang, Yongbin Zhou, Zhaoshi Xu, Jun Chen, Haiyan Li, Ming Chen & Youzhi Ma. (2021) Nuclear transport factor GmNTF2B‐1 enhances soybean drought tolerance by interacting with oxidoreductase GmOXR17 to reduce reactive oxygen species content. The Plant Journal 107:3, pages 740-759.
Crossref
Ke Zhang, Xingtao Zhou, Junqiao Wang, Yujia Zhou, Wucheng Qi, Haihong Chen, Shaoping Nie & Mingyong Xie. (2021) Dendrobium officinale polysaccharide triggers mitochondrial disorder to induce colon cancer cell death via ROS-AMPK-autophagy pathway. Carbohydrate Polymers 264, pages 118018.
Crossref
Ying Shen, Bin Zhang, Yanwei Su, Shaikh Atik Badshah, Xiaofei Wang, Xin Li, Yanru Xue, Li Xie, Zhe Wang, Zhouqi Yang, Ge Zhang & Peng Shang. (2020) Iron Promotes Dihydroartemisinin Cytotoxicity via ROS Production and Blockade of Autophagic Flux via Lysosomal Damage in Osteosarcoma. Frontiers in Pharmacology 11.
Crossref
Gang Liu, Junjun Wang, Gaojian Zhang, Huihui Zhang, Yin Zhu, Hongkang Xu, Lin Kong, Yupeng Tian, Xiaojiao Zhu & Hongping Zhou. (2020) Dynamic cyclic behaviors of lipid droplets monitored by two-photon fluorescence probe with high photostability. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 228, pages 117766.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.