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Clinical Toxicology Volume 54, 2016 - Issue 6
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Clinical Research

Efficacy and effectiveness of anti-digoxin antibodies in chronic digoxin poisonings from the DORA study (ATOM-1)

Betty S. ChanClinical Toxicology Unit and Emergency Department, Prince of Wales Hospital, Sydney, New South Wales, Australia; ;New South Wales Poisons Information Centre, Sydney Children's Hospital at Westmead, Sydney, New South Wales, Australia; Correspondence[email protected]
,
Geoffrey K. IsbisterNew South Wales Poisons Information Centre, Sydney Children's Hospital at Westmead, Sydney, New South Wales, Australia; ;Clinical Toxicology Research Group, University of Newcastle, Newcastle, Australia; ;Department of Clinical Toxicology and Pharmacology, Calvary Mater Newcastle, Newcastle, Australia;
,
Margaret O’LearyClinical Toxicology Research Group, University of Newcastle, Newcastle, Australia; ;Department of Clinical Toxicology and Pharmacology, Calvary Mater Newcastle, Newcastle, Australia;
,
Angela ChiewClinical Toxicology Unit and Emergency Department, Prince of Wales Hospital, Sydney, New South Wales, Australia; ;New South Wales Poisons Information Centre, Sydney Children's Hospital at Westmead, Sydney, New South Wales, Australia;
&
Nicholas A. BuckleyNew South Wales Poisons Information Centre, Sydney Children's Hospital at Westmead, Sydney, New South Wales, Australia; ;Department of Clinical Pharmacology, University of Sydney, Sydney, New South Wales, Australia
Pages 488-494 | Received 15 Nov 2015, Accepted 31 Mar 2016, Published online: 27 Apr 2016

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Betty S. Chan, Geoffrey K. Isbister, Angela Chiew, Katherine Isoardi & Nicholas A. Buckley. (2022) Clinical experience with titrating doses of digoxin antibodies in acute digoxin poisoning. (ATOM-6). Clinical Toxicology 60:4, pages 433-439.
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Betty S. Chan, Geoffrey K. Isbister, Colin B. Page, Katherine Z. Isoardi, Angela L. Chiew, Katharine A. Kirby & Nicholas A. Buckley. (2019) Clinical outcomes from early use of digoxin-specific antibodies versus observation in chronic digoxin poisoning (ATOM-4). Clinical Toxicology 57:7, pages 638-643.
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Lucy M. Bracken, Betty S. H. Chan & Nicholas A. Buckley. (2019) Physiologically based pharmacokinetic modelling of acute digoxin toxicity and the effect of digoxin-specific antibody fragments. Clinical Toxicology 57:2, pages 117-124.
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Anselm Wong & Shaun L Greene. (2018) Successful treatment of Nerium oleander toxicity with titrated Digoxin Fab antibody dosing. Clinical Toxicology 56:7, pages 678-680.
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Betty S. Chan, Angela Chiew, Geoffrey K. Isbister, Margaret O’Leary & Nicholas A. Buckley. (2017) Authors’ responses to letter to the editor re: “Efficacy and effectiveness of anti-digoxin antibodies in chronic digoxin poisonings from the DORA study (ATOM-1)”. Clinical Toxicology 55:1, pages 64-64.
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Josh J Wang, Angela Regina & Robert S. Hoffman. (2017) Letter in response to “Efficacy and effectiveness of anti-digoxin antibodies in chronic digoxin poisonings from the DORA study (ATOM-1)” . Clinical Toxicology 55:1, pages 63-63.
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Articles from other publishers (18)

Paul Andrews, Kurt Anseeuw, Dipak Kotecha, Frédéric Lapostolle & Ruben Thanacoody. (2023) Diagnosis and practical management of digoxin toxicity: a narrative review and consensus. European Journal of Emergency Medicine 30:6, pages 395-401.
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Marieke A. Dijkman, Femke M. J. Gresnigt & Dylan W. de Lange. (2023) Digoxin-specific antibodies: a novel dosing strategy. Netherlands Heart Journal.
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Nathalie Oeffl, Lukas Schober, Patrick Faudon, Sabrina Schweintzger, Martin Manninger, Martin Köstenberger, Hannes Sallmon, Daniel Scherr & Stefan Kurath-Koller. (2023) Antiarrhythmic Drug Dosing in Children—Review of the Literature. Children 10:5, pages 847.
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Jon B. Cole & Ann M. Arens. (2022) Cardiotoxic Medication Poisoning. Emergency Medicine Clinics of North America 40:2, pages 395-416.
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Maude St-Onge. (2021) Cardiovascular Drug Toxicity. Critical Care Clinics 37:3, pages 563-576.
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Angela L Chiew, Nicholas A Buckley, Andis Graudins & Venita L Munir. (2020) Review article: Up (to) date for Australian Toxicology and Toxinology guidelines. Emergency Medicine Australasia 33:1, pages 6-8.
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Nicole M Acquisto, Giles W Slocum, Matthew H Bilhimer, Nadia I Awad, Stephanie Baker Justice, Gregory F Kelly, Therese Makhoul, Asad E Patanwala, Gary D Peksa, Blake Porter, Donna M Shuler Truoccolo, Cierra N Treu, Kyle A Weant & Michael C Thomas. (2020) Key articles and guidelines for the emergency medicine clinical pharmacist: 2011-2018 update. American Journal of Health-System Pharmacy 77:16, pages 1284-1335.
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Amitava Dasgupta & Matthew D. Krasowski. 2020. Therapeutic Drug Monitoring Data. Therapeutic Drug Monitoring Data 27 42 .
Nancy G. Murphy, D. Ruth Bona & Theresa A. Hurley. (2017) A system-wide solution to antidote stocking in emergency departments: the Nova Scotia antidote program. CJEM 21:1, pages 37-46.
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George Braitberg. 2019. Critical Care Nephrology. Critical Care Nephrology 574 588.e3 .
Tom N. Lea-Henry, Jane E. Carland, Sophie L. Stocker, Jacob Sevastos & Darren M. Roberts. (2018) Clinical Pharmacokinetics in Kidney Disease. Clinical Journal of the American Society of Nephrology 13:7, pages 1085-1095.
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Hooman Arbabian, Hwee Min Lee & Andis Graudins. (2018) Elderly patients with suspected chronic digoxin toxicity: A comparison of clinical characteristics of patients receiving and not receiving digoxin‐Fab. Emergency Medicine Australasia 30:2, pages 242-248.
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Bruno Mégarbane. 2017. Critical Care Toxicology. Critical Care Toxicology 1 10 .
Bruno Mégarbane. 2017. Critical Care Toxicology. Critical Care Toxicology 807 819 .
Bruno Mégarbane. 2017. Critical Care Toxicology. Critical Care Toxicology 2715 2724 .
. (2016) Anti digoxin polyclonal antibody/digoxin. Reactions Weekly 1615:1, pages 22-22.
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Bruno Mégarbane. 2016. Critical Care Toxicology. Critical Care Toxicology 1 14 .
Bruno Mégarbane. 2016. Critical Care Toxicology. Critical Care Toxicology 1 10 .

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