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Clinical Toxicology Volume 56, 2018 - Issue 3
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Clinical Research

Accuracy of the paracetamol-aminotransferase product to predict hepatotoxicity in paracetamol overdose treated with a 2-bag acetylcysteine regimen

Anselm WongDepartment of Medicine, School of Clinical Sciences, Monash University, Victoria, Australia; ;Austin Toxicology Service and Victorian Poisons Information Centre, Austin Health, Victoria, Australia; Correspondence[email protected]
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,
Marco L. A. SivilottiDepartments of Emergency Medicine and Biomedical & Molecular Sciences, Queen’s University, Kingston, Canada; View further author information
,
Naren GunjaWestmead and Blacktown Hospitals, Western Sydney Toxicology Service, Sydney, Australia; View further author information
,
Richard McNultyWestmead and Blacktown Hospitals, Western Sydney Toxicology Service, Sydney, Australia; View further author information
&
Andis GraudinsDepartment of Medicine, School of Clinical Sciences, Monash University, Victoria, Australia; ;Monash Toxicology Service, Monash Health, Dandenong, AustraliaView further author information
Pages 182-188 | Received 25 May 2017, Accepted 07 Jul 2017, Published online: 31 Jul 2017

Citations (7)

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Chun En Yau, Haoyang Chen, Bryant Po-Yuen Lim, Mingwei Ng, R. Ponampalam, Daniel Yan Zheng Lim, Yip Han Chin & Andrew Fu Wah Ho. (2023) Performance of the paracetamol-aminotransferase multiplication product in risk stratification after paracetamol (acetaminophen) poisoning: a systematic review and meta-analysis. Clinical Toxicology 61:1, pages 1-11.
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Sarah E. Hodgson & Anselm Wong. (2022) Comment on Single bag high dose intravenous N-acetylcysteine associated with decreased hepatotoxicity compared to triple bag intravenous N-acetylcysteine in high-risk acetaminophen ingestions. Clinical Toxicology 60:5, pages 662-663.
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Anselm Wong, Natalie Homer, James W. Dear, Kay Weng Choy, James Doery & Andis Graudins. (2019) Paracetamol metabolite concentrations following low risk overdose treated with an abbreviated 12-h versus 20-h acetylcysteine infusion. Clinical Toxicology 57:5, pages 312-317.
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Christopher Hoyte & Richard C. Dart. (2019) Transition to two-bag intravenous acetylcysteine for acetaminophen overdose: a poison center’s experience . Clinical Toxicology 57:3, pages 217-218.
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Articles from other publishers (3)

Anselm Wong, Andis Graudins, Kennon Heard, Kim Dalhoff & Marco L.A. Sivilotti. (2019) Improving the management of the paracetamol poisoned patient. EClinicalMedicine 12, pages 10.
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Janice M. Pettie, Thomas M. Caparrotta, Robert W. Hunter, Emma E. Morrison, David M. Wood, Paul I. Dargan, Ruben H. Thanacoody, Simon H.L. Thomas, Muhammad E.M.O. Elamin, Ben Francis, David J. Webb, Euan A. Sandilands, Michael Eddleston & James W. Dear. (2019) Safety and Efficacy of the SNAP 12-hour Acetylcysteine Regimen for the Treatment of Paracetamol Overdose. EClinicalMedicine 11, pages 11-17.
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Anselm Wong, Richard McNulty, David Taylor, Marco Sivilotti, Shaun Greene, Naren Gunja, Zeff Koutsogiannis & Andis Graudins. (2019) The NACSTOP Trial: A Multicenter, Cluster‐Controlled Trial of Early Cessation of Acetylcysteine in Acetaminophen Overdose. Hepatology 69:2, pages 774-784.
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