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Clinical Toxicology Volume 57, 2019 - Issue 1
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Clinical Research

Early administration of Fab antivenom resulted in faster limb recovery in copperhead snake envenomation patients

Victoria E. AndersonRocky Mountain Poison and Drug Center, Denver Health and Hospital Authority, Denver, CO, USA; Correspondence[email protected]
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Charles J. GerardoDivision of Emergency Medicine, Duke University School of Medicine, Durham, NC, USA; View further author information
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Malin Rapp-OlssonRocky Mountain Poison and Drug Center, Denver Health and Hospital Authority, Denver, CO, USA; View further author information
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Sean P. BushDepartment of Emergency Medicine, Brody School of Medicine, Greenville, NC, USA; View further author information
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Michael E. MullinsDivision of Emergency Medicine, Washington University School of Medicine, St. Louis, MO, USA; ORCID Iconhttp://orcid.org/0000-0001-8605-0217View further author information
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Spencer GreeneDepartment of Emergency Medicine, Baylor College of Medicine, Houston, TX, USA; View further author information
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Eric A. ToschlogDepartment of Surgery, Brody School of Medicine, Greenville, NC, USA; View further author information
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Eugenia QuackenbushDepartment of Emergency Medicine, University of North Carolina, Chapel Hill, NC, USA; View further author information
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S. Rutherfoord RoseDepartment of Emergency Medicine, Virginia Commonwealth University, Richmond, VA, USA; View further author information
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Richard B. SchwartzDepartment of Emergency Medicine and Hospital Services, Medical College of Georgia, Augusta, GA, USA; View further author information
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Nathan P. CharltonDepartment of Emergency Medicine, University of Virginia, Charlottesville, VA, USA; View further author information
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Brandon LewisTexas A&M Health Science Center, College Station, TX, USA; View further author information
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Kurt C. KleinschmidtDepartment of Emergency Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA; View further author information
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Kapil SharmaDepartment of Emergency Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA; View further author information
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Eric J. LavonasDepartment of Emergency Medicine and Rocky Mountain Poison and Drug Center, Denver Health and Hospital Authority, Denver, CO, USAView further author information
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Pages 25-30 | Received 11 Mar 2018, Accepted 13 Jun 2018, Published online: 03 Sep 2018

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Fatima Ramirez-Cueva, Adam Larsen, Elise Knowlton, Kelsey Baab, Robin Rainey Kiehl, Amy Hendrix, Michelle Condren & Megan Woslager. (2022) Predictors of FabAV use in copperhead envenomation. Clinical Toxicology 60:5, pages 609-614.
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B. Z. Wilson, J. Larsen, G. Smelski, S. Dudley & F. M. Shirazi. (2021) Use of Crotalidae equine immune F(ab’)2 antivenom for treatment of an Agkistrodon envenomation. Clinical Toxicology 59:11, pages 1023-1026.
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Eric J. Lavonas, Victoria E. Anderson & Charles J. Gerardo. (2020) In reply to Dr. Shah and Dr. Beuhler. Clinical Toxicology 58:3, pages 223-224.
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Kartik R. Shah & Michael C. Beuhler. (2020) Comment on “Early administration of fab antivenom resulted in faster limb recovery in copperhead snake envenomation patients”. Clinical Toxicology 58:3, pages 222-223.
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Spencer C. Greene, Liliana Morales-Perez, Michael Pallini, Carlos Vences & Jennifer Carnell. (2020) LTE: comment on “Incidence of allergic reactions to crotalidae polyvalent immune fab”. Clinical Toxicology 58:3, pages 214-215.
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Joseph Carpenter, Brian Patrick Murray, Lindsay Schaack Rothstein & Alaina Steck. (2019) In reply to: “Early administration of fab antivenom resulted in faster limb recovery in copperhead snake envenomation patients” by Anderson et al., CLIN TOXICOL 2018, ahead of print. Clinical Toxicology 57:7, pages 673-674.
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Articles from other publishers (16)

Jason B. Hack, Kori L. Brewer & William J. Meggs. (2023) Comparing cost of F(.ab’)2AV vs FabAV in the treatment of copperhead envenomation–One center's experience. The American Journal of Emergency Medicine 73, pages 17-19.
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Nicklaus Brandehoff, Alicia Dalton, Claire Daugherty, Richard C. Dart & Andrew A. Monte. (2023) Total CroFab and Anavip Antivenom Vial Administration in US Rattlesnake Envenomations: 2019–2021. Journal of Medical Toxicology 19:3, pages 248-254.
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Anna Tupetz, Loren K. Barcenas, Ashley J. Phillips, Joao Ricardo Nickenig Vissoci & Charles J. Gerardo. (2022) BITES study: A qualitative analysis among emergency medicine physicians on snake envenomation management practices. PLOS ONE 17:1, pages e0262215.
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Steven A. SeifertJames O. ArmitageElda E. Sanchez. (2022) Snake Envenomation. New England Journal of Medicine 386:1, pages 68-78.
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Soumyadeep Bhaumik, Deepti Beri, Jyoti Tyagi, Mike Clarke, Sanjib Kumar Sharma, Paula R Williamson & Jagnoor Jagnoor. (2022) Outcomes in intervention research on snakebite envenomation: a systematic review. F1000Research 11, pages 628.
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Tein-Shun Tsai, Chun-Chieh Liu & Po-Chun Chuang. (2021) Personal Experience of Daboia siamensis Envenomation. Case Reports in Medicine 2021, pages 1-3.
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Spencer Greene, David Cheng, Gary M. Vilke & Garret Winkler. (2021) How Should Native Crotalid Envenomation Be Managed in the Emergency Department?. The Journal of Emergency Medicine 61:1, pages 41-48.
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Ashley M. Martin, George S. Wang & Kevin Poel. (2021) Use of both Fab and F(ab’)2 fragment antivenom in a pediatric patient for treatment of a North American Crotalidae envenomation. The American Journal of Emergency Medicine 45, pages 677.e1-677.e3.
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Cecilie Knudsen, Jonas A. Jürgensen, Sofie Føns, Aleksander M. Haack, Rasmus U. W. Friis, Søren H. Dam, Sean P. Bush, Julian White & Andreas H. Laustsen. (2021) Snakebite Envenoming Diagnosis and Diagnostics. Frontiers in Immunology 12.
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Charles J. Gerardo, Elizabeth Silvius, Seth Schobel, John C. Eppensteiner, Lauren M. McGowan, Eric A. Elster, Allan D. Kirk & Alexander T. Limkakeng. (2021) Association of a Network of Immunologic Response and Clinical Features With the Functional Recovery From Crotalinae Snakebite Envenoming. Frontiers in Immunology 12.
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Po-Chun ChuangKang-Wei ChangShih-Yu ChengHsiu-Yung Pan, Kuo-Chen HuangYii-Ting HuangChao-Jui Li. (2021) Benefits of Early In-Hospital Antivenom Administration to Patients with Protobothrops mucrosquamatus Envenomation. The American Journal of Tropical Medicine and Hygiene 104:1, pages 323-328.
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Stephen W. Miller, Kevin C. Osterhoudt, Amanda S. Korenoski, Ketan Patel & Sakthivel Vaiyapuri. (2020) Exotic Snakebites Reported to Pennsylvania Poison Control Centers: Lessons Learned on the Demographics, Clinical Effects, and Treatment of These Cases. Toxins 12:12, pages 755.
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Jing-Hua Lin, Che-Min Lo, Ssu-Han Chuang, Chao-Hung Chiang, Sheng-Der Wang, Tsung-Yi Lin, Jiunn-Wang Liao & Dong-Zong Hung. (2020) Collocation of avian and mammal antibodies to develop a rapid and sensitive diagnostic tool for Russell's Vipers Snakebite. PLOS Neglected Tropical Diseases 14:9, pages e0008701.
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Jing-Hua Lin, Wang-Chou Sung, Jiunn-Wang Liao & Dong-Zong Hung. (2020) A Rapid and International Applicable Diagnostic Device for Cobra (Genus Naja) Snakebites. Toxins 12:9, pages 572.
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Craig Cocchio, Jami Johnson & Shari Clifton. (2020) Review of North American pit viper antivenoms. American Journal of Health-System Pharmacy 77:3, pages 175-187.
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Eric J. Lavonas, Randy I. Burnham, John Schwarz, Eugenia Quackenbush, Brandon Lewis, S. Rutherfoord Rose, Spencer Greene, Eric A. Toschlog, Nathan P. Charlton, Michael E. Mullins, Richard Schwartz, David Denning, Kapil Sharma, Kurt Kleinschmidt, Sean P. Bush, Victoria E. Anderson, Adit A. Ginde & Charles J. Gerardo. (2019) Recovery from Copperhead Snake Envenomation: Role of Age, Sex, Bite Location, Severity, and Treatment. Journal of Medical Toxicology 16:1, pages 17-23.
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