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Clinical Toxicology Volume 57, 2019 - Issue 11
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Clinical Research

A randomized controlled study comparing high-dose insulin to vasopressors or combination therapy in a porcine model of refractory propranolol-induced cardiogenic shock

Katherine G. KatzungDepartment of Emergency Medicine, Abbott Northwestern Hospital, Minneapolis, MN, USA; Correspondence[email protected]
ORCID Iconhttp://orcid.org/0000-0003-0150-3761View further author information
ORCID Icon,
Jenna M. LeroyDepartment of Emergency Medicine, Regions Hospital, St. Paul, MN, USA; View further author information
,
Sean P. BoleyDepartment of Emergency Medicine, United Hospital, St. Paul, MN, USAORCID Iconhttp://orcid.org/0000-0003-1340-6416View further author information
ORCID Icon,
Samuel J. StellpflugDepartment of Emergency Medicine, Regions Hospital, St. Paul, MN, USA; View further author information
,
Joel S. HolgerDepartment of Emergency Medicine, Regions Hospital, St. Paul, MN, USA; View further author information
&
Kristin M. EngebretsenDepartment of Emergency Medicine, Regions Hospital, St. Paul, MN, USA; View further author information
Pages 1073-1079 | Received 19 Dec 2018, Accepted 01 Feb 2019, Published online: 26 Feb 2019

Citations (14)

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Read on this site (3)

Jon B. Cole, Samantha C. Lee, Matthew E. Prekker, Nathan M. Kunzler, Kelly A. Considine, Brian E. Driver, Michael A. Puskarich & Travis D. Olives. (2022) Vasodilation in patients with calcium channel blocker poisoning treated with high-dose insulin: a comparison of amlodipine versus non-dihydropyridines. Clinical Toxicology 60:11, pages 1205-1213.
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Erik Lindeman, Jonas Ålebring, Anna Johansson, Johan Ahlner, Fredrik C. Kugelberg & Johanna Nordmark Grass. (2020) The unknown known: non-cardiogenic pulmonary edema in amlodipine poisoning, a cohort study. Clinical Toxicology 58:11, pages 1042-1049.
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Joe-Anthony Rotella, Shaun L. Greene, Zeff Koutsogiannis, Andis Graudins, Yit Hung Leang, Kelvin Kuan, Helen Baxter, Elyssia Bourke & Anselm Wong. (2020) Treatment for beta-blocker poisoning: a systematic review. Clinical Toxicology 58:10, pages 943-983.
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Articles from other publishers (11)

Saskia J. Rietjens, Tessa E. van Riemsdijk, Maaike A. Sikma & Dylan W. de Lange. (2023) High‐dose insulin should NOT be used without vasopressors in calcium channel blocker toxicity. British Journal of Clinical Pharmacology 89:4, pages 1275-1278.
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Matthew T. Stanton. (2022) Part II : Interactive case: Toxicology and poison control . JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY 5:12, pages 1332-1337.
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Jon B. Cole & Ann M. Arens. (2022) Cardiotoxic Medication Poisoning. Emergency Medicine Clinics of North America 40:2, pages 395-416.
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Jacob H Cole, Scott B Hughey, Phillip G Geiger, Kamala J Rapp-Santos & Gregory J Booth. (2022) Hemodynamic Effects of Cardiovascular Medications in a Normovolemic and Hemorrhaged Yorkshire-cross Swine Model. Comparative Medicine 72:1, pages 38-44.
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Audrey E. Tinsman & Tara J. Bellis. (2021) Hyperinsulinemia/euglycemia and intravenous lipid emulsion therapy for the management of severe amlodipine toxicosis in a cat. Clinical Case Reports 9:12.
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Shameen Salam, Brandon Nornhold & Jihad Mallat. (2021) Massive metoprolol overdose requiring ECMO: brief review of the evidence behind recommended treatments. BMJ Case Reports 14:5, pages e232130.
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Justin N. Corcoran, Katherine J. Jacoby, Travis D. Olives, Stacey A. Bangh & Jon B. Cole. (2020) Persistent Hyperinsulinemia Following High-Dose Insulin Therapy: A Case Report. Journal of Medical Toxicology 16:4, pages 465-469.
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Jenna M. LeRoy, Sean P. Boley, Justin N. Corcoran, Kristin M. Engebretsen & Samuel J. Stellpflug. (2020) Effect of Methylene Blue on a Porcine Model of Amlodipine Toxicity. Journal of Medical Toxicology 16:4, pages 398-404.
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Bruno Levy, Thomas Klein & Antoine Kimmoun. (2020) Vasopressor use in cardiogenic shock. Current Opinion in Critical Care 26:4, pages 411-416.
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Jon B Cole, Justin N Corcoran, Kristin M Engebretsen & Samuel J Stellpflug. (2020) Use of a Porcine Model to Evaluate the Risks and Benefits of Vasopressors in Propranolol Poisoning. Journal of Medical Toxicology 16:2, pages 212-221.
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Sean P. Boley, Rebecca B. Mackenzie, Jenna M. LeRoy, Kristin M. Engebretsen & Samuel J. Stellpflug. (2019) Development and Feasibility of a Porcine Model of Amlodipine Toxicity. Journal of Medical Toxicology 16:1, pages 61-66.
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