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Clinical Toxicology Volume 58, 2020 - Issue 1
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Basic Research

Intramuscular sodium tetrathionate as an antidote in a clinically relevant swine model of acute cyanide toxicity

Tara B. Hendry-HoferDepartment of Emergency Medicine, School of Medicine, University of Colorado, Aurora, CO, USA; Correspondence[email protected]
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Alyssa E. WiteofDepartment of Emergency Medicine, School of Medicine, University of Colorado, Aurora, CO, USA; View further author information
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Patrick C. NgDepartment of Emergency Medicine, School of Medicine, University of Colorado, Aurora, CO, USA; ;Rocky Mountain Poison and Drug Center, Denver Health and Hospital Authority, Denver, CO, USA; View further author information
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Sari B. MahonBeckman Laser Institute, University of California, Irvine, Irvine, CA, USA; View further author information
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Matthew BrennerBeckman Laser Institute, University of California, Irvine, Irvine, CA, USA; View further author information
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Gerry R. BossDepartment of Medicine, University of California, San Diego, La Jolla, CA, USA; View further author information
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Vikhyat S. BebartaDepartment of Emergency Medicine, School of Medicine, University of Colorado, Aurora, CO, USA; ;USAF Reserve, Office of the Chief Scientist, San Antonio, TX, USAORCID Iconhttp://orcid.org/0000-0001-8816-1199View further author information
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Pages 29-35 | Received 29 Nov 2018, Accepted 24 Mar 2019, Published online: 22 Apr 2019

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Adriano Chan, Jangwoen Lee, Subrata Bhadra, Nesta Bortey-Sam, Tara B. Hendry-Hofer, Vikhyat S. Bebarta, Sari B. Mahon, Matthew Brenner, Brian Logue, Renate B. Pilz & Gerry R. Boss. (2022) Development of sodium tetrathionate as a cyanide and methanethiol antidote. Clinical Toxicology 60:3, pages 332-341.
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Tara B. Hendry-Hofer, Carter C. Severance, Subrata Bhadra, Patrick C. Ng, Kirsten Soules, Dennean S. Lippner, Diane M. Hildenberger, Melissa O. Rhoomes, Jessica N. Winborn, Brian A. Logue, Gary A. Rockwood & Vikhyat S. Bebarta. (2022) Evaluation of aqueous dimethyl trisulfide as an antidote to a highly lethal cyanide poisoning in a large swine model. Clinical Toxicology 60:1, pages 95-101.
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D. S. Lippner, D. M. Hildenberger, M. O. Rhoomes, J. N. Winborn, H. Dixon, J. McDonough & G. A. Rockwood. (2022) A novel aqueous dimethyl trisulfide formulation is effective at low doses against cyanide toxicity in non-anesthetized mice and rats. Clinical Toxicology 60:1, pages 83-94.
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Ophir Lavon, Gary A. Rockwood & Arik Eisenkraft. (2021) Can isosorbide dinitrate oral spray serve as an immediate bridging therapy for a mass cyanide poisoning?. Clinical Toxicology 59:8, pages 734-739.
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Shondra M. Neumeister & Joshua P. Gray. (2021) The Strategic National Stockpile: identification, support, and acquisition of medical countermeasures for CBRN incidents. Toxicology Mechanisms and Methods 31:4, pages 308-321.
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Articles from other publishers (5)

Killiam A. Argote-Araméndiz & Alejandra Caycedo. 2024. Ciottone's Disaster Medicine. Ciottone's Disaster Medicine 697 704 .
Vik S Bebarta, Xu Shi, Shunning Zheng, Tara B Hendry-Hofer, Carter C Severance, Matthew M Behymer, Gerry R Boss, Sari Mahon, Matthew Brenner, Gregory T Knipp, Vincent Jo Davisson, Randall T Peterson, Calum A MacRae, Jared Rutter, Robert E Gerszten & Anjali K Nath. (2023) Intramuscular administration of glyoxylate rescues swine from lethal cyanide poisoning and ameliorates the biochemical sequalae of cyanide intoxication. Toxicological Sciences 191:1, pages 90-105.
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Patrick C. Ng, Joseph K. Maddry & Vikhyat S. Bebarta. 2022. History of Modern Clinical Toxicology. History of Modern Clinical Toxicology 279 286 .
Ki H. Ma, Dennean S. Lippner, Kelly A. Basi, Susan M. DeLeon, William R. Cappuccio, Melissa O. Rhoomes, Diane M. Hildenberger, Heidi M. Hoard-Fruchey & Gary A. Rockwood. (2021) Cyanide Poisoning Compromises Gene Pathways Modulating Cardiac Injury in Vivo . Chemical Research in Toxicology 34:6, pages 1530-1541.
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Subrata Bhadra, Vikhyat S. Bebarta, Tara B. Hendry-Hofer, Dennean S. Lippner, Jessica N. Winborn, Gary A. Rockwood & Brian A. Logue. (2021) Analysis of the Soil Fumigant, Dimethyl Disulfide, in Swine Blood by Dynamic Headspace Gas Chromatography–Mass Spectroscopy. Journal of Chromatography A 1638, pages 461856.
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