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Clinical Toxicology Volume 58, 2020 - Issue 12
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Clinical Research

Drug-specific risk of severe QT prolongation following acute drug overdose

Sharan L. CamplemanToxicology Investigators Consortium, American College of Medical Toxicology, Phoenix, AZ, USA; View further author information
,
Jeffery BrentDepartment of Medicine, University of Colorado School of Medicine, Aurora, CO, USA; View further author information
,
Anthony F. PizonDivision of Medical Toxicology, Department of Emergency Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA; View further author information
,
Joshua ShulmanDivision of Medical Toxicology, Department of Emergency Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA; View further author information
,
Paul WaxDepartment of Emergency Medicine, UT Southwestern Medical Center, Dallas, TX, USA; View further author information
,
Alex F. ManiniDivision of Medical Toxicology, Department of Emergency Medicine, Elmhurst Hospital Center, Icahn School of Medicine at Mount Sinai, New York, NY, USACorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0001-8276-9320View further author information
ORCID Icon & on behalf of the Toxicology Investigators’ Consortium (ToxIC) show all
Pages 1326-1334 | Received 13 Jan 2020, Accepted 17 Mar 2020, Published online: 07 Apr 2020

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Nicholas Husak, James Brewer Leonard, Hyunuk Seung & Wendy Klein-Schwartz. (2022) Single-substance trazodone exposures reported to US poison centers from 2000 to 2019. Clinical Toxicology 60:9, pages 1032-1038.
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N. A. Shnayder, A. V. Kidyaeva, E. E. Vaiman, A. R. Asadullin, M. M. Petrova, D. S. Kaskaeva, G. V. Matyushin, A. A. Evsyukov, E. V. Galko, N. P. Garganeeva, G. A. Chumakova, N. V. Lareva, N. G. Neznanov & R. F. Nasyrova. (2023) Role of Pharmacokinetics and Pharmacogenetics of Antidepressant-Induced Prolongation of the QT Interval and Torsade de Pointes in Patients with Mental Disorders. Personalized Psychiatry and Neurology 3:2, pages 72-119.
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Michael D. SimpsonC. James WatsonJames D. WhitledgeMichael C. MonuteauxMichele M. Burns. (2023) Intensive Care Interventions Among Children With Toxicologic Exposures to Cardiovascular Medications. Pediatric Critical Care Medicine 24:11, pages 893-900.
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Yanyan Qu, Ting Li, Zhichao Liu, Dongying Li & Weida Tong. (2023) DICTrank: The largest reference list of 1318 human drugs ranked by risk of drug-induced cardiotoxicity using FDA labeling. Drug Discovery Today 28:11, pages 103770.
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Kamaldeep Singh, Arpit Jain, Ishita Panchal, Hritik Madan, Anubhav Gupta, Aakanksha Sharma, Surabhi Gupta, Anastas Kostojchin, Anmol Singh, Ishanjit Singh Sandhu, Jayesh Mittal, Loveleen Bhogal, Shiny Teja Kolli, Vishal Reddy Bejugam, Salil Chaturvedi, Akhil Bhalla & Shobhit Piplani. (2023) Ondansetron-induced QT prolongation among various age groups: a systematic review and meta-analysis. The Egyptian Heart Journal 75:1.
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Yasin H. Balcioglu, Hasan Gokcay, Simge S. Kirlioglu Balcioglu & Mustafa Solmaz. (2023) Increased Dispersion of Ventricular Repolarization as an Arrhythmic Risk Marker in Drug-free Patients With Major Depressive Disorder: A Preliminary Comparative Study. Journal of Psychiatric Practice 29:4, pages 282-290.
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Pınar DEMİR GÜNDOĞMUŞ, İbrahim GÜNDOĞMUŞ & Emrah AKSAKAL. (2023) ECG Changes in Patients with Amitriptyline Intoxication; P, QT, QTC, T and PR Wave Dispersion: A Retrospective Study. Eurasian Journal of Toxicology 5:1, pages 5-10.
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Bikash K. Pradhan, Bala Chakravarty Neelappu, J. Sivaraman, Doman Kim & Kunal Pal. (2023) A Review on the Applications of Time-Frequency Methods in ECG Analysis. Journal of Healthcare Engineering 2023, pages 1-34.
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Binata Marik, Nupur Mahajan, Rohit Sarkar, Rochana Mitra, Rajiv Dua & Sumit Aggarwal. (2022) A Qualitative Assessment among Personnel Working in Community-Led Development Program Settings Regarding Sexualized Substance Use. Brain Sciences 12:11, pages 1590.
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Anna Colom Gordillo, Lidia Martínez Sánchez, Carla Pretel Echaburu, Victoria Trenchs Sainz de la Maza, Julià Gotzens Bersch & Carles Luaces Cubells. (2022) Intoxicación no intencionada por anticatarrales: medicamentos poco útiles y potencialmente tóxicos. Anales de Pediatría 97:5, pages 326-332.
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Anna Colom Gordillo, Lidia Martínez Sánchez, Carla Pretel Echaburu, Victoria Trenchs Sainz de la Maza, Julià Gotzens Bersch & Carles Luaces Cubells. (2022) Unintentional poisoning by cough and cold medications: Drugs with little usefulness and potential toxicity. Anales de Pediatría (English Edition) 97:5, pages 326-332.
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Kaitlin Ryan, Paul Benz, Amy Zosel, Andrew Farkas & Jillian Theobald. (2022) QTc Prolongation in Poison Center Exposures to CredibleMeds List of Substances with “Known Risk of Torsades de Pointes”. Cardiovascular Toxicology 22:9, pages 866-877.
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Daniel J. McCabe, Eric McGillis & Benjamin A. Willenbring. (2022) The Timing of Clinical Effects of Bupropion Misuse Via Insufflation Reported to a Regional Poison Center. The Journal of Emergency Medicine 62:2, pages 175-181.
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Siri Shastry, Eleanor R. Aluise, Lynne D. Richardson, Rajesh Vedanthan & Alex F. Manini. (2021) Delayed QT Prolongation: Derivation of a Novel Risk Factor for Adverse Cardiovascular Events from Acute Drug Overdose. Journal of Medical Toxicology 17:4, pages 363-371.
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Daniel J. McCabe, Eric McGillis & Benjamin A. Willenbring. (2021) Clinical effects of intravenous bupropion misuse reported to a regional poison center. The American Journal of Emergency Medicine 47, pages 86-89.
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Allan Sauvat, Fabiola Ciccosanti, Francesca Colavita, Martina Di Rienzo, Concetta Castilletti, Maria Rosaria Capobianchi, Oliver Kepp, Laurence Zitvogel, Gian Maria Fimia, Mauro Piacentini & Guido Kroemer. (2020) On-target versus off-target effects of drugs inhibiting the replication of SARS-CoV-2. Cell Death & Disease 11:8.
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Siri Shastry, Judson Ellis, George Loo, Rajesh Vedanthan, Lynne D. Richardson & Alex F. Manini. (2020) Antidotal Sodium Bicarbonate Therapy: Delayed QTc Prolongation and Cardiovascular Events. Journal of Medical Toxicology.
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