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Poison Centre Research

Clinical outcome of massive acetaminophen overdose treated with standard-dose N-acetylcysteine

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Pages 932-936 | Received 16 Dec 2020, Accepted 03 Feb 2021, Published online: 23 Feb 2021

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Read on this site (3)

Annabelle S Chidiac, Nicholas A Buckley, Firouzeh Noghrehchi & Rose Cairns. (2023) Paracetamol (acetaminophen) overdose and hepatotoxicity: mechanism, treatment, prevention measures, and estimates of burden of disease. Expert Opinion on Drug Metabolism & Toxicology 19:5, pages 297-317.
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Stephanie L. Link, Garrett Rampon, Stephen Osmon, Anthony J. Scalzo & Barry H. Rumack. (2022) Fomepizole as an adjunct in acetylcysteine treated acetaminophen overdose patients: a case series. Clinical Toxicology 60:4, pages 472-477.
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Articles from other publishers (5)

Ari B. Filip & Michael E. Mullins. (2022) Fomepizole should be used more liberally in paracetamol overdose. British Journal of Clinical Pharmacology 89:2, pages 594-598.
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Nicolas Primas, Guillaume Lano, Damien Brun, Christophe Curti, Marion Sallée, Emmanuelle Sampol-Manos, Edouard Lamy, Charleric Bornet, Stéphane Burtey & Patrice Vanelle. (2023) Stability Study of Parenteral N-Acetylcysteine, and Chemical Inhibition of Its Dimerization. Pharmaceuticals 16:1, pages 72.
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H. K. Ruben Thanacoody. (2022) Large paracetamol overdose – Higher dose NAC is NOT required. British Journal of Clinical Pharmacology 89:1, pages 39-42.
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A. Yu. Simonova, M. M. Potskhveriya, M. V. Belova, K. K. Ilyashenko, V. V. Kulabuhov, N. Y. Stolbova & A. E. Klyuev. (2022) On the Treatment of Acute Poisoning With Paracetamol. Russian Sklifosovsky Journal "Emergency Medical Care" 11:2, pages 249-257.
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Guangbin ChenHongzhou Lu. (2022) Oral high-dose acetylcysteine: Effective against the Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)?. Drug Discoveries & Therapeutics 16:3, pages 139-141.
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