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Clinical Toxicology Volume 45, 2007 - Issue 1

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Case Report

Atomoxetine-induced hepatitis in a child

Sasko D. Stojanovski College of Pharmacy, Ohio State University and Children's Research Institute, Columbus, Ohio, USA

, Pharm.D,

Marcel J. Casavant Colleges of Pharmacy, Medicine and Public Health, Ohio State University and Central Ohio Poison Center, Children's Research Institute, Columbus, Ohio, USA

, F.A.C.M.T , M.D. , F.A.C.E.P.,

Hayat M. Mousa Colleges of Medicine and Public Health, Ohio State University, and Children's Research Institute, Columbus, Ohio, USA

, M.D.,

Peter Baker Colleges of Medicine and Public Health, Ohio State University, and Children's Research Institute, Columbus, Ohio, USA

, M.D. &

Milap C. Nahata Colleges of Pharmacy, Medicine and Public Health, Ohio State University, Children's Hospital, and Children's Research Institute, Columbus, Ohio, USA

, F.A.A.A.S , Pharm.D. , M.S. , F.C.C.P.

Pages 51-55 | Received 10 Feb 2006, Accepted 03 May 2006, Published online: 07 Oct 2008

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https://doi.org/10.1080/15563650600795644

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Rolf Teschke & Gaby Danan. (2023) Idiosyncratic DILI and RUCAM under One Hat: The Global View. Livers 3:3, pages 397-433.
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Christopher L Robinson, Katelyn Parker, Saurabh Kataria, Evan Downs, Rajesh Supra, Alan D. Kaye, Omar Viswanath & Ivan Urits. (2022) Viloxazine for the Treatment of Attention Deficit Hyperactivity Disorder. Health Psychology Research 10:3.
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Lindsy Pang & Romil Sareen. (2021) Retrospective analysis of adverse events associated with non-stimulant ADHD medications reported to the united states food and drug administration. Psychiatry Research 300, pages 113861.
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Eve A. Roberts. 2021. Liver Disease in Children. Liver Disease in Children 348 382 .

Kevin R. MacKenzie, Mingkun Zhao, Mercedes Barzi, Jin Wang, Karl-Dimiter Bissig, Mirjana Maletic-Savatic, Sung Yun Jung & Feng Li. (2020) Metabolic profiling of norepinephrine reuptake inhibitor atomoxetine. European Journal of Pharmaceutical Sciences 153, pages 105488.
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Rolf Teschke & Gaby Danan. (2020) Worldwide Use of RUCAM for Causality Assessment in 81,856 Idiosyncratic DILI and 14,029 HILI Cases Published 1993–Mid 2020: A Comprehensive Analysis. Medicines 7:10, pages 62.
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Frank DiPaola & Jean P. Molleston. (2018) Drug-Induced Liver Injury in Children. Current Hepatology Reports 17:3, pages 283-291.
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Rolf Teschke & Gaby Danan. 2018. Drug-Induced Liver Toxicity. Drug-Induced Liver Toxicity 555 594 .

Victoria A. Reed, Jan K. Buitelaar, Ernie Anand, Kathleen Ann Day, Tamás Treuer, Himanshu P. Upadhyaya, David R. Coghill, Ludmila A. Kryzhanovskaya & Nicola C. Savill. (2016) The Safety of Atomoxetine for the Treatment of Children and Adolescents with Attention-Deficit/Hyperactivity Disorder: A Comprehensive Review of Over a Decade of Research. CNS Drugs 30:7, pages 603-628.
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. 2016. Meyler's Side Effects of Drugs. Meyler's Side Effects of Drugs 738 762 .

Gaby Danan & Rolf Teschke. (2015) RUCAM in Drug and Herb Induced Liver Injury: The Update. International Journal of Molecular Sciences 17:1, pages 14.
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Lily HechtmanJosephine EliaRichard Kingsley, Christopher Lam, Toshinobu Takeda, Rachel de Berardinis, Seth Laracy, Jillan Sackett, Shih-Ching Tang, Martin Schardt, Kristina Nivus, Hakon Hakonarson & Sibel Algon. 2013. Clinical Management of Attention Deficit Hyperactivity Disorder. Clinical Management of Attention Deficit Hyperactivity Disorder 72 102 .

Dongyi (Tony) Du, Esther H. Zhou, John Goldsmith, Clark Nardinelli & Tarek A. Hammad. (2012) Atomoxetine Use During a Period of FDA Actions. Medical Care 50:11, pages 987-992.
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Karim Sedky, Racha Nazir, Aditya Joshi, Gagandeep Kaur & Steven Lippmann. (2012) Which psychotropic medications induce hepatotoxicity?. General Hospital Psychiatry 34:1, pages 53-61.
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Rebecca Rendleman & John T. Walkup. 2012. Swaiman's Pediatric Neurology. Swaiman's Pediatric Neurology 664 702 .

Ayten ErdoganFigen OzcayEthem PiskinMehmet Goksin KaramanBanu BilezikciMustafa CalikIshak TekinMehmet Haberal. (2011) Idiosyncratic Liver Failure Probably Associated with Atomoxetine: A Case Report. Journal of Child and Adolescent Psychopharmacology 21:3, pages 295-297.
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Brandy Hood & Michael J. Nowicki. (2010) Eosinophilic Hepatitis in an Adolescent During Lisdexamfetamine Dimesylate Treatment for ADHD. Pediatrics 125:6, pages e1510-e1513.
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Reginald P. Sequeira. 2010. Side Effects of Drugs Annual 32 - A worldwide yearly survey of new data and trends in adverse drug reactions and interactions. Side Effects of Drugs Annual 32 - A worldwide yearly survey of new data and trends in adverse drug reactions and interactions 1 28 .

Grazia DellʼAgnello, Alessandro Zuddas, Gabriele Masi, Paolo Curatolo, Dante Besana & Andrea Rossi. (2009) Use of Atomoxetine in Patients with Attention-Deficit Hyperactivity Disorder and Co-Morbid Conditions. CNS Drugs 23:9, pages 739-753.
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James Rochon, Petr Protiva, Leonard B. Seeff, Robert J. Fontana, Suthat Liangpunsakul, Paul B. Watkins, Timothy Davern & John G. McHutchison. (2008) Reliability of the Roussel Uclaf Causality Assessment Method for assessing causality in drug-induced liver injury. Hepatology 48:4, pages 1175-1183.
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Johnny Graham & David Coghill. (2008) Adverse Effects of Pharmacotherapies for Attention-Deficit Hyperactivity Disorder. CNS Drugs 22:3, pages 213-237.
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Mark E Bangs, Ling Jin, Shuyu Zhang, Durisala Desaiah, Albert J Allen, Holly A Read, Arie Regev & Joachim F Wernicke. (2008) Hepatic Events Associated with Atomoxetine Treatment for??Attention-Deficit??Hyperactivity Disorder. Drug Safety 31:4, pages 345-354.
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L. C. Smoot, L. A. Boothby & R. C. Gillett. (2007) Clinical assessment and treatment of ADHD in children. International Journal of Clinical Practice 61:10, pages 1730-1738.
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Jackie Y. W. Cheng, Ronald Y. L. Chen, John S. N. Ko & Emil M. L. Ng. (2007) Efficacy and safety of atomoxetine for attention-deficit/hyperactivity disorder in children and adolescents—meta-analysis and meta-regression analysis. Psychopharmacology 194:2, pages 197-209.
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. (2007) Current awareness: Pharmacoepidemiology and drug safety. Pharmacoepidemiology and Drug Safety 16:9.
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