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Clinical Toxicology Volume 46, 2008 - Issue 3
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Research Article

Oral administration of fomepizole produces similar blood levels as identical intravenous dose

Jeanna Marraffa Department of Emergency Medicine, SUNY Upstate Medical University, Syracuse, New York, USA
,
Alan Forrest State University of New York Buffalo Schools of Pharmacy and Medicine, Buffalo, New York, USA
,
William Grant Department of Emergency Medicine, SUNY Upstate Medical University, Syracuse, New York, USA
,
Christine Stork Department of Emergency Medicine, SUNY Upstate Medical University, Syracuse, New York, USA
,
Kenneth McMartin Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA
&
Mary Ann Howland St. Johns University College of Pharmacy, New York City Poison Control Center, New York, New York, USA
Pages 181-186 | Received 15 Feb 2007, Accepted 29 Mar 2007, Published online: 20 Jan 2009

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Ari B. Filip, Sarah E. Berg, Michael E. Mullins & Evan S. Schwarz. (2022) Fomepizole as an adjunctive therapy for acetaminophen poisoning: cases reported to the toxicology investigators consortium (ToxIC) database 2015–2020. Clinical Toxicology 60:9, pages 1006-1011.
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Kartik R. Shah, Carolyn Fox, Ann-Jeannette Geib, Christine Murphy, Kathryn Kopec, William Kerns II, Anna Dulaney & Michael C. Beuhler. (2021) Fomepizole as an adjunctive treatment in severe acetaminophen ingestions: a case series. Clinical Toxicology 59:1, pages 71-72.
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Michael E. Mullins, Lauren H. Yeager & William E. Freeman. (2020) Metabolic and mitochondrial treatments for severe paracetamol poisoning: a systematic review. Clinical Toxicology 58:12, pages 1284-1296.
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Jeanna M. Marraffa, Christine M. Stork & Mary Ann Howland. (2020) Comment on consensus statements on the approach to patients in a methanol poisoning outbreak. Clinical Toxicology 58:6, pages 503-503.
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Jeffrey A. Kraut. (2015) Diagnosis of toxic alcohols: limitations of present methods. Clinical Toxicology 53:7, pages 589-595.
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Rebeca Gracia, Brian Latimer & Kenneth E. McMartin. (2012) Kinetics of fomepizole in pregnant rats. Clinical Toxicology 50:8, pages 743-748.
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Kenneth E. McMartin, C. Simon Sebastian, David Dies & Dag Jacobsen. (2012) Kinetics and metabolism of fomepizole in healthy humans. Clinical Toxicology 50:5, pages 375-383.
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Bruno Mégarbane, Pascal Houzé & Frédéric J. Baud. (2008) Oral fomepizole administration to treat ethylene glycol and methanol poisonings: advantages and limitations. Clinical Toxicology 46:10, pages 1097-1097.
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Articles from other publishers (18)

Ari B. Filip & Michael E. Mullins. (2022) Fomepizole should be used more liberally in paracetamol overdose. British Journal of Clinical Pharmacology 89:2, pages 594-598.
Crossref
Matthew T. Stanton. (2022) Part II : Interactive case: Toxicology and poison control . JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY 5:12, pages 1332-1337.
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Kenneth E. McMartin. 2022. History of Modern Clinical Toxicology. History of Modern Clinical Toxicology 213 230 .
Kenneth McMartin & Jeffrey Brent. (2021) Analysis of Fomepizole Elimination in Methanol- and Ethylene Glycol-Poisoned Patients. Journal of Medical Toxicology 18:1, pages 19-29.
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Zahra Nekoukar, Zakaria Zakariaei, Fatemeh Taghizadeh, Fatemeh Musavi, Elham Sadat Banimostafavi, Ali Sharifpour, Nasrin Ebrahim Ghuchi, Mahdi Fakhar, Rabeeh Tabaripour & Sepideh Safanavaei. (2021) Methanol poisoning as a new world challenge: A review. Annals of Medicine and Surgery 66, pages 102445.
Crossref
Kartik R. Shah & Michael C. Beuhler. (2020) Fomepizole as an Adjunctive Treatment in Severe Acetaminophen Toxicity. The American Journal of Emergency Medicine 38:2, pages 410.e5-410.e6.
Crossref
Ravi Kumar Jairam, Sadanand Rangnathrao Mallurwar, Suresh P. Sulochana, Devaraj V. Chandrasekhar, Umesh Todmal, Ravi Kanth Bhamidipati, Wolfgang Richter, Nuggehally R. Srinivas & Ramesh Mullangi. (2019) Prediction of Human Pharmacokinetics of Fomepizole from Preclinical Species Pharmacokinetics Based on Normalizing Time Course Profiles. AAPS PharmSciTech 20:6.
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Knut Erik Hovda, Kenneth McMartin & Dag Jacobsen. 2017. Critical Care Toxicology. Critical Care Toxicology 1 18 .
Kenneth McMartin, Knut Erik Hovda & Dag Jacobsen. 2017. Critical Care Toxicology. Critical Care Toxicology 1 14 .
Knut Erik Hovda, Kenneth McMartin & Dag Jacobsen. 2017. Critical Care Toxicology. Critical Care Toxicology 1769 1786 .
Kenneth McMartin, Knut Erik Hovda & Dag Jacobsen. 2017. Critical Care Toxicology. Critical Care Toxicology 2829 2842 .
Jeffrey A. Kraut. (2016) Approach to the Treatment of Methanol Intoxication. American Journal of Kidney Diseases 68:1, pages 161-167.
Crossref
Kenneth McMartin, Dag Jacobsen & Knut Erik Hovda. (2016) Antidotes for poisoning by alcohols that form toxic metabolites. British Journal of Clinical Pharmacology 81:3, pages 505-515.
Crossref
Knut Erik Hovda, Kenneth McMartin & Dag Jacobsen. 2016. Critical Care Toxicology. Critical Care Toxicology 1 18 .
Kenneth McMartin, Knut Erik Hovda & Dag Jacobsen. 2016. Critical Care Toxicology. Critical Care Toxicology 1 14 .
K E McMartin. (2010) Antidotes for Alcohol and Glycol Toxicity: Translating Mechanisms Into Treatments. Clinical Pharmacology & Therapeutics 88:3, pages 400-404.
Crossref
Michelle Bestic, Martha Blackford & Michael Reed. (2009) Fomepizole: A Critical Assessment of Current Dosing Recommendations. The Journal of Clinical Pharmacology 49:2, pages 130-137.
Crossref
KE Hovda & D Jacobsen. (2008) Expert opinion: fomepizole may ameliorate the need for hemodialysis in methanol poisoning. Human & Experimental Toxicology 27:7, pages 539-546.
Crossref

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