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Clinical Toxicology Volume 46, 2008 - Issue 3
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Case Report

Acute pulmonary edema associated with naphazoline ingestion

Hidetada Fukushima Department of Emergency and Critical Care Medicine, Nara Medical University, Kashihara City, Japan
, M.D.,
Kazunobu Norimoto Department of Emergency and Critical Care Medicine, Nara Medical University, Kashihara City, Japan
, M.D.,
Tadahiko Seki Department of Emergency and Critical Care Medicine, Nara Medical University, Kashihara City, Japan
, M.D.,
Takashi Nishiguchi Department of Emergency and Critical Care Medicine, Nara Medical University, Kashihara City, Japan
, M.D.,
Tatsuya Nakamura Department of Emergency and Critical Care Medicine, Nara Medical University, Kashihara City, Japan
, M.D.,
Toshifumi Konobu Department of Emergency and Critical Care Medicine, Nara Medical University, Kashihara City, Japan
, M.D.,
Kenji Nishio Department of Emergency and Critical Care Medicine, Nara Medical University, Kashihara City, Japan
, M.D. &
Kazuo Okuchi Department of Emergency and Critical Care Medicine, Nara Medical University, Kashihara City, Japan
, M.D. show all
Pages 254-256 | Received 09 Dec 2005, Accepted 20 Mar 2006, Published online: 20 Jan 2009

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J. A. Lowry & J. T. Brown. (2014) Significance of the imidazoline receptors in toxicology. Clinical Toxicology 52:5, pages 454-469.
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Hiroki Uehara, Dai Taguchi, Toshiaki Osanai, Yutaro Oe, Takaki Yoshimura, Shinichi Yashiro, Takahiro Gunji & Masaki Okuyama. (2023) Naphazoline intoxication with transient QT prolongation and acute myocardial injury. Journal of Cardiology Cases.
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Haixia He, Jiao Sha, Yameng Wan, Renren Sun, Gaoliang Jiang, Yu Li, Tao Li & Baozeng Ren. (2021) Solid-liquid phase equilibrium of naphazoline hydrochloride in eleven neat solvents: Determination, solvent effect, molecular simulation and thermodynamic analysis. Journal of Molecular Liquids 325, pages 114748.
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Borys Kuzminov, Vira Turkina & Yuriy Кuzminov. (2018) Rationale for naphazoline effects in-depth study. Current Issues in Pharmacy and Medical Sciences 31:1, pages 29-33.
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Yuko Ono, Nozomi Ono & Kazuaki Shinohara. (2017) Tissue Hypoperfusion, Hypercoagulopathy, and Kidney and Liver Dysfunction after Ingestion of a Naphazoline-Containing Antiseptic. Case Reports in Emergency Medicine 2017, pages 1-5.
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Robert L. PageIIII, Cindy L. O’Bryant, Davy Cheng, Tristan J. Dow, Bonnie Ky, C. Michael Stein, Anne P. Spencer, Robin J. Trupp & JoAnn Lindenfeld. (2016) Drugs That May Cause or Exacerbate Heart Failure. Circulation 134:6.
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T. Novais, M. Bourdelin, O. Le Vavasseur & H. Bontemps. (2016) Hypertension art?rielle maligne et d?compensation cardiaque globale apr?s consommation abusive de vasoconstricteur par voie nasale?: ? propos d?un cas et revue de la litt?rature. La Revue de M?decine Interne 37:6, pages 424-428.
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Mumin Hakim, Hina Walia, Mahmood Rafiq, Timothy Grannell, Richard S. Cartabuke & Joseph D. Tobias. (2016) Oxymetazoline Metered Dose Spray: Factors Affecting Delivery Volume. The Journal of Pediatric Pharmacology and Therapeutics 21:3, pages 247-251.
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. 2016. Meyler's Side Effects of Drugs. Meyler's Side Effects of Drugs 25 31 .
Gregory J. Latham & David S. Jardine. (2013) Oxymetazoline and hypertensive crisis in a child: can we prevent it?. Pediatric Anesthesia 23:10, pages 952-956.
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G. Mortuaire, L. de Gabory, M. François, G. Massé, F. Bloch, N. Brion, R. Jankowski & E. Serrano. (2013) Rebound congestion and rhinitis medicamentosa: Nasal decongestants in clinical practice. Critical review of the literature by a medical panel. European Annals of Otorhinolaryngology, Head and Neck Diseases 130:3, pages 137-144.
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G. Mortuaire, L. de Gabory, M. François, G. Massé, F. Bloch, N. Brion, R. Jankowski & E. Serrano. (2013) Effet rebond et rhinite aux vasoconstricteurs nasaux en pratique clinique. Revue critique de la littérature par un groupe d’experts. Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale 130:3, pages 140-148.
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Lourdes M. Figueiras-Graillet, Manuel Mart?nez-Sell?s, Esther Perez-David & Francisco Fernandez-Avil?s. (2013) Reversible cardiomyopathy due to chronic use of xylometazoline topical nasal spray. International Journal of Cardiology 164:2, pages e17-e18.
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Atsushi Yamaguchi, Takashi Mato, Hidenori Oi, Kazuyuki Nakata, Koichi Inokuchi, Kuniyoshi Kumaido & Satoru Sugiyama. (2011) Pulmonary edema caused by intoxication with a disinfectant containing naphazoline: a case report. Nihon Kyukyu Igakukai Zasshi 22:6, pages 291-296.
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Marie Granier, Christophe Dadure, Sophie Bringuier, Marie-Caroline Bonnet-Boyer, Yves Ryckwaert, Estelle Loriaux & Xavier Capdevila. (2009) Intranasal lidocaine plus naphazoline nitrate improves surgical conditions and perioperative analgesia in septorhinoplasty surgeryLa lidocaïne intranasale ajoutée au nitrate de naphazoline améliore les conditions chirurgicales et l’analgésie périopératoire lors de chirurgie de rhinoseptoplastie. Canadian Journal of Anesthesia/Journal canadien d'anesthésie 56:2, pages 102-108.
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