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Research Article

Are recommended doses of acetaminophen hepatotoxic for recently abstinent alcoholics? A randomized trial

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Pages 243-249 | Received 23 Mar 2007, Accepted 11 May 2007, Published online: 20 Jan 2009

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Mitchell R. McGill & Hartmut Jaeschke. (2018) Biomarkers of drug-induced liver injury: progress and utility in research, medicine, and regulation. Expert Review of Molecular Diagnostics 18:9, pages 797-807.
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Steven A. Seifert, Daniel Kovnat, Victoria E. Anderson, Jody L. Green, Richard C. Dart & Kennon J. Heard. (2016) Acute hepatotoxicity associated with therapeutic doses of intravenous acetaminophen. Clinical Toxicology 54:3, pages 282-285.
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Eric J Lavonas, James F Fries, Daniel E Furst, Kenneth J Rothman, Andy Stergachis, Allen J Vaida, Daniel Zelterman, Kate M Reynolds, Jody L Green & Richard C Dart. (2012) Comparative risks of non-prescription analgesics: a structured topic review and research priorities. Expert Opinion on Drug Safety 11:1, pages 33-44.
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Gordon Liss, Sushil Rattan & James H Lewis. (2010) Predicting and preventing acute drug-induced liver injury: what's new in 2010?. Expert Opinion on Drug Metabolism & Toxicology 6:9, pages 1047-1061.
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Gordon Liss & James H Lewis. (2009) Drug-induced liver injury: what was new in 2008?. Expert Opinion on Drug Metabolism & Toxicology 5:8, pages 843-860.
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Articles from other publishers (13)

Su Hyun Kim, Hye-Kyung Jung, Ein-Soon Shin, Jin Seo Lee, Yon Ju Ryu, Kyoung Sup Hong, Soo Mee Bang, Yoon-Seok Chang, Chan Kyu Kim, Byung Wan Lee, Seung-Jae Hong & Chang Oh Kim. (2021) Guidelines for Safe Drug Use. The Korean Journal of Medicine 96:3, pages 225-235.
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Alexandre Louvet, Line Carolle Ntandja Wandji, Elise Lemaître, Marion Khaldi, Claire Lafforgue, Florent Artru, Benoît Quesnel, Guillaume Lassailly, Sébastien Dharancy & Philippe Mathurin. (2021) Acute Liver Injury With Therapeutic Doses of Acetaminophen: A Prospective Study. Hepatology 73:5, pages 1945-1955.
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Gary Eichenbaum, Kyunghee Yang, Yeshitila Gebremichael, Brett A. Howell, F. Jay Murray, David Jacobson-Kram, Hartmut Jaeschke, Edwin Kuffner, Cathy K. Gelotte, John C.K. Lai, Daniele Wikoff & Evren Atillasoy. (2020) Application of the DILIsym® Quantitative Systems Toxicology drug-induced liver injury model to evaluate the carcinogenic hazard potential of acetaminophen. Regulatory Toxicology and Pharmacology 118, pages 104788.
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Angela L Chiew, Christian Gluud, Jesper Brok & Nick A Buckley. (2018) Interventions for paracetamol (acetaminophen) overdose. Cochrane Database of Systematic Reviews 2018:2.
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Imane Saad Albichr & Philippe Hantson. (2018) Le paracétamol à dose thérapeutique : quelles populations à risque d’hépatotoxicité ?. Toxicologie Analytique et Clinique 30:1, pages 19-34.
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Kelly L. Hayward, Elizabeth E. Powell, Katharine M. Irvine & Jennifer H. Martin. (2016) Can paracetamol (acetaminophen) be administered to patients with liver impairment?. British Journal of Clinical Pharmacology 81:2, pages 210-222.
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Barry Rumack, Kennon Heard, Jody Green, Donald Albert, Becki Bucher‐Bartelson, Michael Bodmer, Marco L. A. Sivilotti & Richard C. Dart. (2012) Effect of Therapeutic Doses of Acetaminophen (up to 4 g/day) on Serum Alanine Aminotransferase Levels in Subjects Consuming Ethanol: Systematic Review and Meta‐analysis of Randomized Controlled Trials. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 32:9, pages 784-791.
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James H. Lewis & David E. Kleiner. 2012. MacSween's Pathology of the Liver. MacSween's Pathology of the Liver 645 760 .
Kennon J. Heard, Jody L. Green & Richard C. Dart. (2012) Serum Alanine Aminotransferase Elevation During 10 Days of Acetaminophen Use in Nondrinkers. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 30:8, pages 818-822.
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R. C. Dart, J. L. Green, E. K. Kuffner, K. Heard, B. Sproule & B. Brands. (2010) The effects of paracetamol (acetaminophen) on hepatic tests in patients who chronically abuse alcohol – a randomized study. Alimentary Pharmacology & Therapeutics 32:3, pages 478-486.
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Timothy E Albertson, Victor M WalkerJrJr, Marilyn R Stebbins, Elisa W Ashton, Kelly P Owen & Mark E Sutter. (2010) A Population Study of the Frequency of High-Dose Acetaminophen Prescribing and Dispensing. Annals of Pharmacotherapy 44:7-8, pages 1191-1195.
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E. Björnsson. (2010) Review article: drug‐induced liver injury in clinical practice. Alimentary Pharmacology & Therapeutics 32:1, pages 3-13.
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N. K. GUPTA & J. H. LEWIS. (2008) Review article: the use of potentially hepatotoxic drugs in patients with liver disease. Alimentary Pharmacology & Therapeutics 28:9, pages 1021-1041.
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