Citations (46)
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J. Von Der Wellen, F. Worek, H. Thiermann & T. Wille. (2013) Investigations of kinetic interactions between lipid emulsions, hydroxyethyl starch or dextran and organophosphorus compounds. Clinical Toxicology 51:10, pages 918-922.
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Paul Wilhelm Elsinghorst, Franz Worek, Horst Thiermann & Timo Wille. (2013) Drug development for the management of organophosphorus poisoning. Expert Opinion on Drug Discovery 8:12, pages 1467-1477.
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. (2013) XXXIII International Congress of the European Association of Poisons Centres and Clinical Toxicologists (EAPCCT) 28–31 May 2013, Copenhagen, Denmark. Clinical Toxicology 51:4, pages 252-378.
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Franz Worek, Nadine Aurbek, Timo Wille, Peter Eyer & Horst Thiermann. (2011) Kinetic prerequisites of oximes as effective reactivators of organophosphate-inhibited acetylcholinesterase: a theoretical approach. Journal of Enzyme Inhibition and Medicinal Chemistry 26:3, pages 303-308.
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Articles from other publishers (42)
Tobias Zellner, Christian Rabe, Jens von der Wellen-Pawlowski, Dagmar Hansen, Harald John, Franz Worek & Florian Eyer. (2022) A case report of severe pirimiphos-methyl intoxication: Clinical findings and cholinesterase status. Frontiers in Pharmacology 13.
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Michael Eddleston. (2022) CON: Oximes should not be used routinely in organophosphorus insecticide poisoning. British Journal of Clinical Pharmacology 88:12, pages 5070-5073.
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Horst Thiermann & Franz Worek. (2022) Pro: Oximes should be used routinely in organophosphate poisoning. British Journal of Clinical Pharmacology 88:12, pages 5064-5069.
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Lukas Gorecki, Ondrej Soukup & Jan Korabecny. (2022) Countermeasures in organophosphorus intoxication: pitfalls and prospects. Trends in Pharmacological Sciences 43:7, pages 593-606.
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Herbert Desel & Andreas Stürer. 2022. History of Modern Clinical Toxicology. History of Modern Clinical Toxicology
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Rauda A. Mohamed, Keat K. Ong, Noor Azilah M. Kasim, Norhana A. Halim, Siti Aminah M. Noor, Victor F. Knight, Nurul Najwa Ab. Rahman & Wan Md Zin W. Yunus. (2021) Transitioning from Oxime to the Next Potential Organophosphorus Poisoning Therapy Using Enzymes. Journal of Chemistry 2021, pages 1-16.
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Kathleen J. Richardson, Jessica L. Schwinck & Marylou V. Robinson. (2021) Organophosphate poisoning. The Nurse Practitioner 46:7, pages 18-21.
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Harald John, Annika Richter, Markus Siegert, Florian Eyer & Horst Thiermann. (2021) Evidence of exposure to organophosphorus toxicants by detection of the propionylated butyrylcholinesterase-derived nonapeptide-adduct as a novel biomarker. Forensic Science International 323, pages 110818.
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David Steindl, Wolfgang Boehmerle, Roland Körner, Damaris Praeger, Marcel Haug, Jens Nee, Adrian Schreiber, Franziska Scheibe, Katharina Demin, Philipp Jacoby, Rudolf Tauber, Sven Hartwig, Matthias Endres & Kai-Uwe Eckardt. (2021) Novichok nerve agent poisoning. The Lancet 397:10270, pages 249-252.
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Niko Amend, Karin V. Niessen, Thomas Seeger, Timo Wille, Franz Worek & Horst Thiermann. (2020) Diagnostics and treatment of nerve agent poisoning—current status and future developments. Annals of the New York Academy of Sciences 1479:1, pages 13-28.
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Franz Worek, Horst Thiermann & Timo Wille. (2020) Organophosphorus compounds and oximes: a critical review. Archives of Toxicology 94:7, pages 2275-2292.
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Tamara Kranawetvogl, Dirk Steinritz, Horst Thiermann & Harald John. (2020) A novel high‐performance liquid chromatography with diode array detector method for the simultaneous quantification of the enzyme‐reactivating oximes obidoxime, pralidoxime, and HI‐6 in human plasma. Drug Testing and Analysis 12:7, pages 938-947.
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N. Amend, J. Langgartner, M. Siegert, T. Kranawetvogl, M. Koller, H. John, C. Pflügler, C. Mögele-Schmid, F. Worek, H. Thiermann & T. Wille. (2020) A case report of cholinesterase inhibitor poisoning: cholinesterase activities and analytical methods for diagnosis and clinical decision making. Archives of Toxicology 94:6, pages 2239-2247.
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Timo Wille, Dirk Steinritz, Franz Worek & Horst Thiermann. (2019) Vergiftungen durch chemische KampfstoffeChemical warfare agent poisoning. Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz 62:11, pages 1370-1377.
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Jonhattan Castañeda-Duque & Victor Manuel Molina Díaz. (2019) Uso de pralidoxima en la intoxicación con metomilo en pastor collie en Medellín (Colombia). Reporte de caso. Revista de la Facultad de Medicina Veterinaria y de Zootecnia 66:2, pages 162-178.
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Andreas Kranawetvogl, Markus Siegert, Florian Eyer, Horst Thiermann & Harald John. (2018) Verification of organophosphorus pesticide poisoning: Detection of phosphorylated tyrosines and a cysteine-proline disulfide-adduct from human serum albumin after intoxication with dimethoate/omethoate. Toxicology Letters 299, pages 11-20.
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Harald John, Markus Siegert, Florian Eyer, Franz Worek, Horst Thiermann & Andreas Kranawetvogl. (2018) Novel cysteine- and albumin-adduct biomarkers to prove human poisoning with the pesticide oxydemeton-S-methyl. Toxicology Letters 294, pages 122-134.
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Jens von der Wellen, Peter Winterhalter, Markus Siegert, Florian Eyer, Horst Thiermann & Harald John. (2018) A toolbox for microbore liquid chromatography tandem-high-resolution mass spectrometry analysis of albumin-adducts as novel biomarkers of organophosphorus pesticide poisoning. Toxicology Letters 292, pages 46-54.
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J. Allister Vale & Sally M. Bradberry. 2017. Critical Care Toxicology. Critical Care Toxicology
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Michael Eddleston & Fazle Rabbi Chowdhury. (2016) Pharmacological treatment of organophosphorus insecticide poisoning: the old and the (possible) new. British Journal of Clinical Pharmacology 81:3, pages 462-470.
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Jishnu K.S. Krishnan, Peethambaran Arun, Abhilash P. Appu, Nivetha Vijayakumar, Taíza H. Figueiredo, Maria F.M. Braga, Sudikshya Baskota, Cara H. Olsen, Natalia Farkas, John Dagata, William H. FreyIIII, John R. Moffett & Aryan M.A. Namboodiri. (2016) Intranasal delivery of obidoxime to the brain prevents mortality and CNS damage from organophosphate poisoning. NeuroToxicology 53, pages 64-73.
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Dirk Steinritz, Florian Eyer, Franz Worek, Horst Thiermann & Harald John. (2016) Repetitive obidoxime treatment induced increase of red blood cell acetylcholinesterase activity even in a late phase of a severe methamidophos poisoning: A case report. Toxicology Letters 244, pages 121-123.
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J. Allister Vale & Sally M. Bradberry. 2016. Critical Care Toxicology. Critical Care Toxicology
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Allister Vale & Marcello Lotti. 2015. Occupational Neurology. Occupational Neurology
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Christopher M. Timperley & John Tattersall. 2015. Best Synthetic Methods. Best Synthetic Methods
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Shamsherjit KaurSatinderpal SinghKaran Singh ChahalAtish Prakash. (2014) Potential pharmacological strategies for the improved treatment of organophosphate-induced neurotoxicity. Canadian Journal of Physiology and Pharmacology 92:11, pages 893-911.
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Horst Thiermann, Franz Worek & Kai Kehe. (2013) Limitations and challenges in treatment of acute chemical warfare agent poisoning. Chemico-Biological Interactions 206:3, pages 435-443.
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Heidi Hrabetz, Horst Thiermann, Norbert Felgenhauer, Thomas Zilker, Bernhard Haller, Jörg Nährig, Bernd Saugel & Florian Eyer. (2013) Organophosphate poisoning in the developed world – A single centre experience from here to the millennium. Chemico-Biological Interactions 206:3, pages 561-568.
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Yun Chen. (2012) Organophosphate-induced brain damage: Mechanisms, neuropsychiatric and neurological consequences, and potential therapeutic strategies. NeuroToxicology 33:3, pages 391-400.
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T. Seeger, K.V. Niessen, P. Langer, J. Gerhardus, F. Worek, H. Friess, R. Bumm, A.L. Mihaljevic & H. Thiermann. (2011) Restoration of nerve agent inhibited muscle force production in human intercostal muscle strips with HI 6. Toxicology Letters 206:1, pages 72-76.
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Horst Thiermann, Dirk Steinritz, Franz Worek, Maria Radtke, Peter Eyer, Florian Eyer, Norbert Felgenhauer & Thomas Zilker. (2011) Atropine maintenance dosage in patients with severe organophosphate pesticide poisoning. Toxicology Letters 206:1, pages 77-83.
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Berthold Drexler, Thomas Seeger, Christian Grasshoff, Horst Thiermann & Bernd Antkowiak. (2011) Long-term evaluation of organophosphate toxicity and antidotal therapy in co-cultures of spinal cord and muscle tissue. Toxicology Letters 206:1, pages 89-93.
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T. Wille, H. Thiermann & F. Worek. (2010) Effect of different buffers on kinetic properties of human acetylcholinesterase and the interaction with organophosphates and oximes. Archives of Toxicology 85:3, pages 193-198.
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Susanne Müller, Marianne Koller, Romain Le Provost, Olivier Lafont, François Estour, Timo Wille, Horst Thiermann, Franz Worek & Georg Reiter. (2011) In vitro detoxification of cyclosarin (GF) by modified cyclodextrins. Toxicology Letters 200:1-2, pages 53-58.
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Berthold Drexler, Bernd Antkowiak, Horst Thiermann, Thomas Seeger & Christian Grasshoff. (2010) Interactions between atropine and etomidate in cortical and spinal networks during cholinergic crisis. Toxicology Letters 198:3, pages 342-347.
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Horst Thiermann, Thomas Seeger, Sascha Gonder, Nadja Herkert, Bernd Antkowiak, Thomas Zilker, Florian Eyer & Franz Worek. (2010) Assessment of neuromuscular dysfunction during poisoning by organophosphorus compounds. Chemico-Biological Interactions 187:1-3, pages 265-269.
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Franz Worek, Nadine Aurbek, Nadja M. Herkert, Harald John, Michael Eddleston, Peter Eyer & Horst Thiermann. (2010) Evaluation of medical countermeasures against organophosphorus compounds: The value of experimental data and computer simulations. Chemico-Biological Interactions 187:1-3, pages 259-264.
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Peter Eyer, Franz Worek, Horst Thiermann & Michael Eddleston. (2010) Paradox findings may challenge orthodox reasoning in acute organophosphate poisoning. Chemico-Biological Interactions 187:1-3, pages 270-278.
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Horst Thiermann, Peter Eyer & Franz Worek. (2010) Muscle force and acetylcholinesterase activity in mouse hemidiaphragms exposed to paraoxon and treated by oximes in vitro. Toxicology 272:1-3, pages 46-51.
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H. Thiermann, T. Zilker, F. Eyer, N. Felgenhauer, P. Eyer & F. Worek. (2009) Monitoring of neuromuscular transmission in organophosphate pesticide-poisoned patients. Toxicology Letters 191:2-3, pages 297-304.
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