Citations (35)
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Konstanze Plaschke, Markus A. Weigand, Fabia Fricke & Jürgen Kopitz. (2016) Neuroinflammation: effect of surgical stress compared to anaesthesia and effect of physostigmine. Neurological Research 38:5, pages 397-405.
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Timo Wille, Horst Thiermann & Franz Worek. (2011) Evaluation of 6,6′-dithionicotinic acid as alternative chromogen in a modified Ellman method—comparison in various species. Toxicology Mechanisms and Methods 21:7, pages 533-537.
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Franz Worek, Nadine Aurbek, Timo Wille, Peter Eyer & Horst Thiermann. (2011) Kinetic prerequisites of oximes as effective reactivators of organophosphate-inhibited acetylcholinesterase: a theoretical approach. Journal of Enzyme Inhibition and Medicinal Chemistry 26:3, pages 303-308.
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Florian Eyer, Franz Worek, Peter Eyer, Norbert Felgenhauer, Mike Haberkorn, Thomas Zilker & Horst Thiermann. (2009) Obidoxime in acute organophosphate poisoning: 1 – clinical effectiveness. Clinical Toxicology 47:8, pages 798-806.
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Articles from other publishers (31)
Michael Eddleston. (2022) CON: Oximes should not be used routinely in organophosphorus insecticide poisoning. British Journal of Clinical Pharmacology 88:12, pages 5070-5073.
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Horst Thiermann & Franz Worek. (2022) Pro: Oximes should be used routinely in organophosphate poisoning. British Journal of Clinical Pharmacology 88:12, pages 5064-5069.
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Jiska Kentrop, Vladimir Savransky, Steven D. Klaassen, Tomas van Groningen, Sara Bohnert, Alex S. Cornelissen, Laura Cochrane, John Barry & Marloes J.A. Joosen. (2021) Pharmacokinetics and efficacy of atropine sulfate/obidoxime chloride co-formulation against VX in a guinea pig model. Regulatory Toxicology and Pharmacology 119, pages 104823.
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Franz Worek, Horst Thiermann & Timo Wille. (2020) Organophosphorus compounds and oximes: a critical review. Archives of Toxicology 94:7, pages 2275-2292.
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Sara Bohnert, Roland M. van den Berg, John Mikler, Steven D. Klaassen & Marloes J.A. Joosen. (2020) Pharmacokinetics of Three Oximes in a Guinea Pig Model and Efficacy of Combined Oxime Therapy. Toxicology Letters 324, pages 86-94.
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Jens von der Wellen, Peter Winterhalter, Markus Siegert, Florian Eyer, Horst Thiermann & Harald John. (2018) A toolbox for microbore liquid chromatography tandem-high-resolution mass spectrometry analysis of albumin-adducts as novel biomarkers of organophosphorus pesticide poisoning. Toxicology Letters 292, pages 46-54.
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J. Allister Vale & Sally M. Bradberry. 2017. Critical Care Toxicology. Critical Care Toxicology
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Konstanze Plaschke, Katharina A. Petersen, Susanne Frankenhauser, Markus A. Weigand, Jürgen Kopitz & Hubert J. Bardenheuer. (2016) The Impact of Plasma Cholinergic Enzyme Activity and Other Risk Factors for the Development of Delirium in Patients Receiving Palliative Care. Journal of Pain and Symptom Management 52:4, pages 525-532.
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J. Allister Vale & Sally M. Bradberry. 2016. Critical Care Toxicology. Critical Care Toxicology
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J. Allister Vale. 2016. Critical Care Toxicology. Critical Care Toxicology
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Allister Vale & Marcello Lotti. 2015. Occupational Neurology. Occupational Neurology
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Christopher M. Timperley & John Tattersall. 2015. Best Synthetic Methods. Best Synthetic Methods
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Horst Thiermann, Franz Worek & Kai Kehe. (2013) Limitations and challenges in treatment of acute chemical warfare agent poisoning. Chemico-Biological Interactions 206:3, pages 435-443.
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Heidi Hrabetz, Horst Thiermann, Norbert Felgenhauer, Thomas Zilker, Bernhard Haller, Jörg Nährig, Bernd Saugel & Florian Eyer. (2013) Organophosphate poisoning in the developed world – A single centre experience from here to the millennium. Chemico-Biological Interactions 206:3, pages 561-568.
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Franz Worek & Horst Thiermann. (2013) The value of novel oximes for treatment of poisoning by organophosphorus compounds. Pharmacology & Therapeutics 139:2, pages 249-259.
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Marco Melzer, Anne Heidenreich, Frederic Dorandeu, Jürgen Gäb, Kai Kehe, Horst Thiermann, Thomas Letzel & Marc-Michael Blum. (2012) In vitro and in vivo efficacy of PEGylated diisopropyl fluorophosphatase (DFPase). Drug Testing and Analysis 4:3-4, pages 262-270.
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T. Seeger, K.V. Niessen, P. Langer, J. Gerhardus, F. Worek, H. Friess, R. Bumm, A.L. Mihaljevic & H. Thiermann. (2011) Restoration of nerve agent inhibited muscle force production in human intercostal muscle strips with HI 6. Toxicology Letters 206:1, pages 72-76.
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Horst Thiermann, Dirk Steinritz, Franz Worek, Maria Radtke, Peter Eyer, Florian Eyer, Norbert Felgenhauer & Thomas Zilker. (2011) Atropine maintenance dosage in patients with severe organophosphate pesticide poisoning. Toxicology Letters 206:1, pages 77-83.
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T. Wille, H. Thiermann & F. Worek. (2010) Effect of different buffers on kinetic properties of human acetylcholinesterase and the interaction with organophosphates and oximes. Archives of Toxicology 85:3, pages 193-198.
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Nick A Buckley, Michael Eddleston, Yi Li, Marc Bevan & Jane Robertson. (2011) Oximes for acute organophosphate pesticide poisoning. Cochrane Database of Systematic Reviews.
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Franz Worek, Nadine Aurbek, Timo Wille, Peter Eyer & Horst Thiermann. (2011) Kinetic analysis of interactions of paraoxon and oximes with human, Rhesus monkey, swine, rabbit, rat and guinea pig acetylcholinesterase. Toxicology Letters 200:1-2, pages 19-23.
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Franz Worek, Timo Wille, Nadine Aurbek, Peter Eyer & Horst Thiermann. (2010) Reactivation of organophosphate-inhibited human, Cynomolgus monkey, swine and guinea pig acetylcholinesterase by MMB-4: A modified kinetic approach. Toxicology and Applied Pharmacology 249:3, pages 231-237.
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Berthold Drexler, Bernd Antkowiak, Horst Thiermann, Thomas Seeger & Christian Grasshoff. (2010) Interactions between atropine and etomidate in cortical and spinal networks during cholinergic crisis. Toxicology Letters 198:3, pages 342-347.
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Marloes J.A. Joosen, Marcel J. van der Schans & Herman P.M. van Helden. (2010) Percutaneous exposure to the nerve agent VX: Efficacy of combined atropine, obidoxime and diazepam treatment. Chemico-Biological Interactions 188:1, pages 255-263.
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Horst Thiermann, Thomas Seeger, Sascha Gonder, Nadja Herkert, Bernd Antkowiak, Thomas Zilker, Florian Eyer & Franz Worek. (2010) Assessment of neuromuscular dysfunction during poisoning by organophosphorus compounds. Chemico-Biological Interactions 187:1-3, pages 265-269.
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Franz Worek, Nadine Aurbek, Nadja M. Herkert, Harald John, Michael Eddleston, Peter Eyer & Horst Thiermann. (2010) Evaluation of medical countermeasures against organophosphorus compounds: The value of experimental data and computer simulations. Chemico-Biological Interactions 187:1-3, pages 259-264.
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Peter Eyer, Franz Worek, Horst Thiermann & Michael Eddleston. (2010) Paradox findings may challenge orthodox reasoning in acute organophosphate poisoning. Chemico-Biological Interactions 187:1-3, pages 270-278.
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Horst Thiermann, Peter Eyer & Franz Worek. (2010) Muscle force and acetylcholinesterase activity in mouse hemidiaphragms exposed to paraoxon and treated by oximes in vitro. Toxicology 272:1-3, pages 46-51.
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Berthold Drexler, Bernd Antkowiak, Horst Thiermann & Christian Grasshoff. (2010) Atropine increases sevoflurane potency in cortical but not spinal networks during cholinergic overstimulation. Toxicology 268:1-2, pages 98-103.
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H. Thiermann, T. Zilker, F. Eyer, N. Felgenhauer, P. Eyer & F. Worek. (2009) Monitoring of neuromuscular transmission in organophosphate pesticide-poisoned patients. Toxicology Letters 191:2-3, pages 297-304.
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