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Research Article

Testicular toxicity and reproductive performance of streptozotocin-induced diabetic male rats: the ameliorating role of silymarin as an antioxidant

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Pages 223-233 | Received 23 Sep 2017, Accepted 20 Feb 2018, Published online: 03 May 2018

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Mehroz Zafar, Ali Sharif, Darosham Khan, Bushra Akhtar, Faqir Muhammad, Muhammad Furqan Akhtar & Tuktum Fatima. (2021) Preventive effect of Euphorbia royleana Boiss on diabetes induced by streptozotocin via modulating oxidative stress and deoxyribonucleic acid damage. Toxin Reviews 40:4, pages 777-790.
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Heidar Heidari Khoei, Sajad Fakhri, Siavash Parvardeh, Zahra Shams Mofarahe, Zahra Baninameh & Mina Vardiani. (2019) Astaxanthin prevents the methotrexate-induced reproductive toxicity by targeting oxidative stress in male mice. Toxin Reviews 38:3, pages 248-254.
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Articles from other publishers (11)

Tita Hariyanti, Ria Margiana, Moaed Emran Al-Gazally, Indrajit Patra, Ghaidaa Raheem Lateef Al-Awsi, Noora Hameed, Dilrabo Kayumova, Mohammad Javed Ansari, Larry Miguel Torres-Criollo, Yasser Fakri Mustafa, Razzagh Abedi-Firouzjah & Bagher Farhood. (2023) The Protective Effects of Silymarin on the Reproductive Toxicity: A Comprehensive Review. Current Medicinal Chemistry 30:39, pages 4421-4449.
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Gomaa Mostafa-He, Muhannad Alanazi & Hassan Abdelmawll. (2023) Antioxidant, Anti-Inflammatory and Antiapoptotic Effect of Mirtazapine Mitigates Cyclophosphamide-Induced Testicular Toxicity in Rats. International Journal of Pharmacology 19:2, pages 166-177.
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Anirban Goutam Mukherjee & Abilash Valsala Gopalakrishnan. (2023) The interplay of arsenic, silymarin, and NF-ĸB pathway in male reproductive toxicity: A review. Ecotoxicology and Environmental Safety 252, pages 114614.
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Xu He, Dayu Wang, Fuquan Zhu, Yuan Jiang, Jiaying Bi, Xinyue Lu, Mingyue Zhao, Weidong Wu & Juan Li. (2022) Astaxanthin alleviates palmitic acid‐induced hindrance of porcine oocyte maturation. Reproduction in Domestic Animals 57:11, pages 1440-1449.
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Amina Talbi, Kamel Khelili, Feriel Remita & Cherif Abdennour. (2022) The benefit of Silybum marianum in ethanol-induced reprotoxicity of male Wistar rat. Brazilian Journal of Pharmaceutical Sciences 58.
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Emrah Hicazi Aksu, Fatih Mehmet Kandemir & Sefa Küçükler. (2021) Ameliorative effect of hesperidin on streptozotocin‐diabetes mellitus‐induced testicular DNA damage and sperm quality degradation in Sprague–Dawley rats. Journal of Food Biochemistry 45:10.
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Ajlaa Sofya Mohd Khalil, Nelli Giribabu, Suseela Yelumalai, Huma Shahzad, Eswar Kumar Kilari & Naguib Salleh. (2021) Myristic acid defends against testicular oxidative stress, inflammation, apoptosis: Restoration of spermatogenesis, steroidogenesis in diabetic rats. Life Sciences 278, pages 119605.
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Zahra Ahmadi, Reza Mohammadinejad, Sahar Roomiani, Elham Ghasemipour Afshar & Milad Ashrafizadeh. (2021) Biological and Therapeutic Effects of Troxerutin: Molecular Signaling Pathways Come into View. Journal of Pharmacopuncture 24:1, pages 1-13.
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Saadet Belhan, Serkan Yıldırım, Zübeyir Huyut, Uğur Özdek, Gökhan Oto & Sermin Algül. (2020) Effects of curcumin on sperm quality, lipid profile, antioxidant activity and histopathological changes in streptozotocin‐induced diabetes in rats. Andrologia 52:6.
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Zeinab Nouri, Marziyeh Hajialyani, Zhila Izadi, Roodabeh Bahramsoltani, Mohammad Hosein Farzaei & Mohammad Abdollahi. (2020) Nanophytomedicines for the Prevention of Metabolic Syndrome: A Pharmacological and Biopharmaceutical Review. Frontiers in Bioengineering and Biotechnology 8.
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Abdul Gofur, Agung Witjoro, Siti Nur Arifah, Mochammad Fitri Atho'illah, Yuslinda Annisa & Sri Rahayu Lestari. (2020) Black soybean tempeh and purple sweet potato improve sperm quality in streptozotocin-induced diabetic rats. Veterinary World 13:11, pages 2534-2540.
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