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Epigenetics Volume 11, 2016 - Issue 10
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Research Paper

The combination of dimethoxycurcumin with DNA methylation inhibitor enhances gene re-expression of promoter-methylated genes and antagonizes their cytotoxic effect

Hazem E. HassanDepartment of Pharmaceutical Sciences, University of Maryland, Baltimore, MD, USA;Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Helwan University, Cairo, Egypt
,
Jean-Arnaud KeitaDepartment of Pharmaceutical Sciences, Albany College of Pharmacy (Vermont Campus), Colchester, VT, USA
,
Lawrence NarayanDepartment of Pharmaceutical Sciences, Albany College of Pharmacy (Vermont Campus), Colchester, VT, USA
,
Sean M. BradyDepartment of Pharmaceutical Sciences, Albany College of Pharmacy (Vermont Campus), Colchester, VT, USA
,
Richard FrederickDepartment of Pharmaceutical Sciences, Albany College of Pharmacy (Vermont Campus), Colchester, VT, USA
,
Samuel CarlsonDepartment of Pharmaceutical Sciences, Albany College of Pharmacy (Vermont Campus), Colchester, VT, USA
,
Karen C. GlassDepartment of Pharmaceutical Sciences, Albany College of Pharmacy (Vermont Campus), Colchester, VT, USA
,
Senthil NatesanDepartment of Experimental and Systems Pharmacology, Washington State University, Spokane, WA, USA
,
Thomm ButtolphDepartment of Neurological Sciences, University of Vermont, Burlington, VT, USA
&
Tamer E. FandyDepartment of Pharmaceutical Sciences, Albany College of Pharmacy (Vermont Campus), Colchester, VT, USACorrespondence[email protected]
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Pages 740-749 | Received 13 Jul 2016, Accepted 12 Aug 2016, Published online: 01 Nov 2016

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Muhammad Sohail, Bin Yu, Zheng Sun, Jiali Liu, Yanli Li, Feng Zhao, Daquan Chen, Xin Yang & Hui Xu. (2022) Complex polymeric nanomicelles co-delivering doxorubicin and dimethoxycurcumin for cancer chemotherapy. Drug Delivery 29:1, pages 1523-1535.
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Articles from other publishers (7)

Suhila Sawesi, Sridhar A. Malkaram, Zakaria Y. Abd Elmageed & Tamer E. Fandy. (2022) Modulation of the activity of histone lysine methyltransferases and demethylases by curcumin analog in leukaemia cells. Journal of Cellular and Molecular Medicine 26:22, pages 5624-5633.
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Margherita Dall’Asta, Mario Barbato, Gabriele Rocchetti, Filippo Rossi, Luigi Lucini, Paolo A Marsan & Licia Colli. (2022) Nutrigenomics: an underestimated contribution to the functional role of polyphenols. Current Opinion in Food Science 47, pages 100880.
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Steven A. Manobianco, Tara Rakiewicz, Lindsay Wilde & Neil D. Palmisiano. (2022) Novel Mechanisms for Post-Transplant Maintenance Therapy in Acute Myeloid Leukemia. Frontiers in Oncology 12.
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Muhammad Sohail, Wenna Guo, Xin Yang, Zhiyong Li, Yanli Li, Hui Xu & Feng Zhao. (2021) A Promising Anticancer Agent Dimethoxycurcumin: Aspects of Pharmacokinetics, Efficacy, Mechanism, and Nanoformulation for Drug Delivery. Frontiers in Pharmacology 12.
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Hetty E. Carraway, Sridhar A. Malkaram, Yana Cen, Aymen Shatnawi, Jun Fan, Hamdy E. A. Ali, Zakaria Y. Abd Elmageed, Thomm Buttolph, James Denvir, Donald A. Primerano & Tamer E. Fandy. (2020) Activation of SIRT6 by DNA hypomethylating agents and clinical consequences on combination therapy in leukemia. Scientific Reports 10:1.
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Thalita Alves Zanetti, Bruna Isabela Biazi, Giuliana Castello Coatti, Adrivanio Baranoski, Lilian Areal Marques, Amanda Cristina Corveloni & Mario Sergio Mantovani. (2019) Mitotic spindle defects and DNA damage induced by dimethoxycurcumin lead to an intrinsic apoptosis pathway in HepG2/C3A cells. Toxicology in Vitro 61, pages 104643.
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Jong Kook Park, Jung Seon Seo, Suk Kyeong Lee, Kenneth K Chan & Hyo-Jeong Kuh. (2018) Combinatorial Antitumor Activity of Oxaliplatin with Epigenetic Modifying Agents, 5-Aza-CdR and FK228, in Human Gastric Cancer Cells. Biomolecules & Therapeutics 26:6, pages 591-598.
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