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Epigenetics Volume 13, 2018 - Issue 2
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Research Paper

Establishment of a high-throughput detection system for DNA demethylating agents

Eriko Okochi-TakadaDivision of Epigenomics, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo104-0045, JapanView further author information
,
Naoko HattoriDivision of Epigenomics, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo104-0045, JapanView further author information
,
Akihiro ItoChemical Genetics Laboratory, RIKEN, 2-1 Hirosawa, Wako, Saitama351-0198, Japan;Chemical Genomics Research Group, RIKEN Center for Sustainable Resource Science, 2-1 Hirosawa, Wako, Saitama351-0198, JapanView further author information
,
Tohru NiwaDivision of Epigenomics, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo104-0045, JapanView further author information
,
Mika WakabayashiDivision of Epigenomics, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo104-0045, JapanView further author information
,
Kana KimuraDivision of Epigenomics, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo104-0045, JapanView further author information
,
Minoru YoshidaChemical Genetics Laboratory, RIKEN, 2-1 Hirosawa, Wako, Saitama351-0198, Japan;Chemical Genomics Research Group, RIKEN Center for Sustainable Resource Science, 2-1 Hirosawa, Wako, Saitama351-0198, Japan;Seed Compounds Exploratory Unit for Drug Discovery Platform, RIKEN Center for Sustainable Resource Science, 2-1 Hirosawa, Wako, Saitama351-0198, JapanView further author information
&
Toshikazu UshijimaDivision of Epigenomics, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo104-0045, JapanCorrespondence[email protected]
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Pages 147-155 | Received 10 Aug 2016, Accepted 27 Nov 2016, Published online: 05 Mar 2018

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Bolormaa Baljinnyam, Michael Ronzetti & Anton Simeonov. (2023) Advances in luminescence-based technologies for drug discovery. Expert Opinion on Drug Discovery 18:1, pages 25-35.
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Articles from other publishers (9)

Xiulong Ma, Liang Zhang, Ling Liu, Dongli Ruan & Chunyang Wang. (2023) Hypermethylated ITGA8 Facilitate Bladder Cancer Cell Proliferation and Metastasis. Applied Biochemistry and Biotechnology.
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Daniel Desaulniers, Paule Vasseur, Abigail Jacobs, M. Cecilia Aguila, Norman Ertych & Miriam N. Jacobs. (2021) Integration of Epigenetic Mechanisms into Non-Genotoxic Carcinogenicity Hazard Assessment: Focus on DNA Methylation and Histone Modifications. International Journal of Molecular Sciences 22:20, pages 10969.
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Maky Ideta-Otsuka, Misato Miyai, Naoki Yamamoto, Ayaka Tsuchimoto, Hideki Tamura, Kentaro Tanemura, Makoto Shibutani & Katsuhide Igarashi. (2021) Development of a new <i>in vitro</i> assay system for evaluating the effects of chemicals on DNA methylation. The Journal of Toxicological Sciences 46:2, pages 83-90.
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Liming Li, Fengjuan Li, Yudong Xia, Xueyuan Yang, Qun Lv, Fang Fang, Qiang Wang, Wenbo Bu, Yan Wang, Ke Zhang, Yi Wu, Junfang Shen & Mingjun Jiang. (2020) UVB induces cutaneous squamous cell carcinoma progression by de novo ID4 methylation via methylation regulating enzymes. EBioMedicine 57, pages 102835.
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Clemens Zwergel, Rossella Fioravanti, Giulia Stazi, Federica Sarno, Cecilia Battistelli, Annalisa Romanelli, Angela Nebbioso, Eduarda Mendes, Alexandra Paulo, Raffaele Strippoli, Marco Tripodi, Dany Pechalrieu, Paola B. Arimondo, Teresa De Luca, Donatella Del Bufalo, Daniela Trisciuoglio, Lucia Altucci, Sergio Valente & Antonello Mai. (2020) Novel Quinoline Compounds Active in Cancer Cells through Coupled DNA Methyltransferase Inhibition and Degradation. Cancers 12:2, pages 447.
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Gizem Tugce Ulu, Yagmur Kiraz & Yusuf Baran. 2020. Biodiversity and Biomedicine. Biodiversity and Biomedicine 441 457 .
Naoko Hattori, Magoichi Sako, Kana Kimura, Naoko Iida, Hideyuki Takeshima, Yoshitaka Nakata, Yutaka Kono & Toshikazu Ushijima. (2019) Novel prodrugs of decitabine with greater metabolic stability and less toxicity. Clinical Epigenetics 11:1.
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Clemens Zwergel, Michael Schnekenburger, Federica Sarno, Cecilia Battistelli, Maria Cristina Manara, Giulia Stazi, Roberta Mazzone, Rossella Fioravanti, Christina Gros, Frédéric Ausseil, Cristina Florean, Angela Nebbioso, Raffaele Strippoli, Toshikazu Ushijima, Katia Scotlandi, Marco Tripodi, Paola B. Arimondo, Lucia Altucci, Marc Diederich, Antonello Mai & Sergio Valente. (2019) Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells. Clinical Epigenetics 11:1.
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Kenneth Lundstrom. (2017) Epigenetics: new possibilities for drug discovery. Future Medicinal Chemistry 9:5, pages 437-441.
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