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Research Paper

Targeted DNA demethylation in human cells by fusion of a plant 5-methylcytosine DNA glycosylase to a sequence-specific DNA binding domain

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Pages 296-303 | Received 21 Dec 2016, Accepted 06 Feb 2017, Published online: 30 Mar 2017

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Teresa Morales-Ruiz, María Victoria García-Ortiz, Iván Devesa-Guerra, Laura Raya-Ruiz, Juan R. Tejedor, Gustavo F. Bayón, Marta I. Sierra, Mario F. Fraga, Rafael R. Ariza & Teresa Roldán-Arjona. (2018) DNA methylation reprogramming of human cancer cells by expression of a plant 5-methylcytosine DNA glycosylase. Epigenetics 13:1, pages 95-107.
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Articles from other publishers (16)

Naohiro Yano & Alexey V. Fedulov. (2023) Targeted DNA Demethylation: Vectors, Effectors and Perspectives. Biomedicines 11:5, pages 1334.
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Xuan Du, Zhenlin Yang, Guohui Xie, Changshi Wang, Laixing Zhang, Kaige Yan, Maojun Yang, Sisi Li, Jian-Kang Zhu & Jiamu Du. (2023) Molecular basis of the plant ROS1-mediated active DNA demethylation. Nature Plants 9:2, pages 271-279.
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Mona Singh, Mony Thakur, Manish Mishra, Manisha Yadav, Rajkamal Vibhuti, Athira M. Menon, Girima Nagda, Ved Prakash Dwivedi, Tikam Chand Dakal & Vinod Yadav. (2021) Gene regulation of intracellular adhesion molecule-1 (ICAM-1): A molecule with multiple functions. Immunology Letters 240, pages 123-136.
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Jenna N. Beyer, Nicole R. Raniszewski & George M. Burslem. (2020) Advances and Opportunities in Epigenetic Chemical Biology. ChemBioChem 22:1, pages 17-42.
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Xiangqiang Zhan, Yuming Lu, Jian‐Kang Zhu & Jose Ramon Botella. (2021) Genome editing for plant research and crop improvement. Journal of Integrative Plant Biology 63:1, pages 3-33.
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Maha Anani, Ikuo Nobuhisa & Tetsuya Taga. (2020) Sry-related High Mobility Group Box 17 Functions as a Tumor Suppressor by Antagonizing the Wingless-related Integration Site Pathway. Journal of Cancer Prevention 25:4, pages 204-212.
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Faezeh Maroufi, Amirhosein Maali, Meghdad Abdollahpour-Alitappeh, Mohammad Hossein Ahmadi & Mehdi Azad. (2020) CRISPR-mediated modification of DNA methylation pattern in the new era of cancer therapy. Epigenomics 12:20, pages 1845-1859.
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Iván Devesa-Guerra, Teresa Morales-Ruiz, Juan Pérez-Roldán, Jara Teresa Parrilla-Doblas, Macarena Dorado-León, María Victoria García-Ortiz, Rafael R. Ariza & Teresa Roldán-Arjona. (2020) DNA Methylation Editing by CRISPR-guided Excision of 5-Methylcytosine. Journal of Molecular Biology 432:7, pages 2204-2216.
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Sultan Abda Neja. (2020) Site-Specific DNA Demethylation as a Potential Target for Cancer Epigenetic Therapy. Epigenetics Insights 13, pages 251686572096480.
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Urbano, Smith, Weeks & Chatterjee. (2019) Gene-Specific Targeting of DNA Methylation in the Mammalian Genome. Cancers 11:10, pages 1515.
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Jara Teresa Parrilla-Doblas, Teresa Roldán-Arjona, Rafael R. Ariza & Dolores Córdoba-Cañero. (2019) Active DNA Demethylation in Plants. International Journal of Molecular Sciences 20:19, pages 4683.
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Renata Z. Jurkowska & Tomasz P. Jurkowski. 2019. The DNA, RNA, and Histone Methylomes. The DNA, RNA, and Histone Methylomes 1 26 .
Yong Lei, Yung-Hsin Huang & Margaret A. Goodell. (2018) DNA methylation and de-methylation using hybrid site-targeting proteins. Genome Biology 19:1.
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Hui Tao, Zheng-Yu Song, Xuan-Sheng Ding, Jing-Jing Yang, Kai-Hu Shi & Jun Li. (2018) Epigenetic signatures in cardiac fibrosis, special emphasis on DNA methylation and histone modification. Heart Failure Reviews 23:5, pages 789-799.
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Jamie E DeNizio, Emily K Schutsky, Kiara N Berrios, Monica Yun Liu & Rahul M Kohli. (2018) Harnessing natural DNA modifying activities for editing of the genome and epigenome. Current Opinion in Chemical Biology 45, pages 10-17.
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Thu Elizabeth Duong & James S. Hagood. (2018) Epigenetic Regulation of Myofibroblast Phenotypes in Fibrosis. Current Pathobiology Reports 6:1, pages 79-96.
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