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Epigenetics Volume 12, 2017 - Issue 10
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Research Paper

Locus-specific DNA methylation in the placenta is associated with levels of pro-inflammatory proteins in cord blood and they are both independently affected by maternal smoking during pregnancy

Sanne D. van OtterdijkInstitute for Prevention and Cancer Epidemiology, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany;Obstetrics and Gynecology Epidemiology Center, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women's Hospital, Harvard Medical School, Boston, MAView further author information
,
Alexandra M. BinderObstetrics and Gynecology Epidemiology Center, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA;Department of Epidemiology, Harvard School of Public Health, Boston, MA, USAView further author information
&
Karin B. MichelsInstitute for Prevention and Cancer Epidemiology, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany;Obstetrics and Gynecology Epidemiology Center, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA;Department of Epidemiology, Harvard School of Public Health, Boston, MA, USACorrespondence[email protected]
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Pages 875-885 | Received 11 May 2017, Accepted 25 Jul 2017, Published online: 12 Dec 2017

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Khosbayar Lkhagvadorj, Karolin F. Meyer, Laura P. Verweij, Wierd Kooistra, Marjan Reinders-Luinge, Henk W. Dijkhuizen, Inge A. M. de Graaf, Torsten Plösch & Machteld N. Hylkema. (2020) Prenatal smoke exposure induces persistent Cyp2a5 methylation and increases nicotine metabolism in the liver of neonatal and adult male offspring. Epigenetics 15:12, pages 1370-1385.
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Articles from other publishers (23)

Krista S. Crider & Arick Wang. (2023) Epigenetic Alterations in Response to Toxic Exposures—The Need to Determine Effect Modification by Nutrient Status. The Journal of Nutrition 153:8, pages 2133-2134.
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Francisco Miralles & Daniel Vaiman. (2023) Abnormal placental DNA methylation following environmental stress: a mere biomarker in a highly sensitive target organ?. Epigenomics.
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Adam E. Enggasser & Rebecca C. Fry. 2023. Handbook of Arsenic Toxicology. Handbook of Arsenic Toxicology 455 483 .
Michael Mortillo & Carmen J. Marsit. (2022) Select Early-Life Environmental Exposures and DNA Methylation in the Placenta. Current Environmental Health Reports 10:1, pages 22-34.
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Srividhya Durbagula, Aruna Korlimarla, Gayatri Ravikumar, Snijesh Valiya Parambath, Sowmyashree Mayur Kaku & Ashok Mysore Visweswariah. (2022) Prenatal epigenetic factors are predisposing for neurodevelopmental disorders—Considering placenta as a model. Birth Defects Research 114:20, pages 1324-1342.
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Rose Schrott, Ashley Song & Christine Ladd-Acosta. (2022) Epigenetics as a Biomarker for Early-Life Environmental Exposure. Current Environmental Health Reports 9:4, pages 604-624.
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Alys Havard, Jonathan James Chandran & Ju Lee Oei. (2022) Tobacco use during pregnancy. Addiction 117:6, pages 1801-1810.
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Kristyn N. Borrelli, Elisha M. Wachman, Jacob A. Beierle, Elizabeth S. Taglauer, Mayuri Jain, Camron D. Bryant & Huiping Zhang. (2022) Effect of Prenatal Opioid Exposure on the Human Placental Methylome. Biomedicines 10:5, pages 1150.
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Alexandra J. Noble, John F. Pearson, Alasdair D. Noble, Joseph M. Boden, L. John Horwood, Martin A. Kennedy & Amy J. Osborne. (2022) DNA methylation analysis using bisulphite-based amplicon sequencing of individuals exposed to maternal tobacco use during pregnancy, and offspring conduct problems in childhood and adolescence. Reproduction, Fertility and Development 34:7, pages 540-548.
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Andrew E. Teschendorff. 2022. Epigenetic Epidemiology. Epigenetic Epidemiology 67 96 .
Kjell Vegard F. Weyde, Ann-Karin Olsen, Nur Duale, Jorke H. Kamstra, Thea S. Skogheim, Ida H. Caspersen, Stephanie M. Engel, Guido Biele, Yankai Xia, Helle M. Meltzer, Heidi Aase & Gro D. Villanger. (2021) Gestational blood levels of toxic metal and essential element mixtures and associations with global DNA methylation in pregnant women and their infants. Science of The Total Environment 787, pages 147621.
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Aurélie Nakamura, Olivier François & Johanna Lepeule. (2021) Epigenetic Alterations of Maternal Tobacco Smoking during Pregnancy: A Narrative Review. International Journal of Environmental Research and Public Health 18:10, pages 5083.
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Giulia F. Del Gobbo, Chaini Konwar & Wendy P. Robinson. (2019) The significance of the placental genome and methylome in fetal and maternal health. Human Genetics 139:9, pages 1183-1196.
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Elisha M. Wachman, Alice Wang, Breanna C. Isley, Jeffery Boateng, Jacob A. Beierle, Aaron Hansbury, Hira Shrestha, Camron Bryant & Huiping Zhang. (2020) Placental OPRM1 DNA methylation and associations with neonatal opioid withdrawal syndrome, a pilot study. Exploration of Medicine 1:3, pages 124-135.
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Fu-Ying Tian, Todd M. Everson, Barry Lester, Tracy Punshon, Brian P. Jackson, Ke Hao, Corina Lesseur, Jia Chen, Margaret R. Karagas & Carmen J. Marsit. (2020) Selenium-associated DNA methylation modifications in placenta and neurobehavioral development of newborns: An epigenome-wide study of two U.S. birth cohorts. Environment International 137, pages 105508.
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Andrew J. Perrin, Carmine M. Pariante & Patricia A. Zunszain. 2020. Perinatal Inflammation and Adult Psychopathology. Perinatal Inflammation and Adult Psychopathology 63 80 .
Andres Cardenas, Sharon M Lutz, Todd M Everson, Patrice Perron, Luigi Bouchard & Marie-France Hivert. (2019) Mediation by Placental DNA Methylation of the Association of Prenatal Maternal Smoking and Birth Weight. American Journal of Epidemiology 188:11, pages 1878-1886.
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Sandra S. Reyes-Aguilar, Irais Poblete-Naredo, Yury Rodríguez-Yáñez, Rogelio O. Corona-Núñez, Christian D. Ortiz-Robles, Emma S. Calderón-Aranda & Arnulfo Albores. (2019) CYP1A1, GSTT1, IL-6 and IL-8 transcription and IL-6 secretion on umbilical endothelial cells from hypertensive pregnant women: Preliminary results. Pregnancy Hypertension 18, pages 63-66.
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Kristi M. Sawyer, Patricia A. Zunszain, Paola Dazzan & Carmine M. Pariante. (2018) Intergenerational transmission of depression: clinical observations and molecular mechanisms. Molecular Psychiatry 24:8, pages 1157-1177.
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Elisha M. Wachman & Lindsay A. Farrer. (2019) The genetics and epigenetics of Neonatal Abstinence Syndrome. Seminars in Fetal and Neonatal Medicine 24:2, pages 105-110.
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Natasha Walker, Panagiotis Filis, Peter J. O'Shaughnessy, Michelle Bellingham & Paul A. Fowler. (2019) Nutrient transporter expression in both the placenta and fetal liver are affected by maternal smoking. Placenta 78, pages 10-17.
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Kristal A. Rychlik & Fenna C. M. Sillé. (2019) Environmental exposures during pregnancy: Mechanistic effects on immunity. Birth Defects Research 111:4, pages 178-196.
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E. M. Wachman, M. J. Hayes, H. Shrestha, F. N. U. Nikita, A. Nolin, L. Hoyo, K. Daigle, H. E. Jones & D. A. Nielsen. (2018) Epigenetic variation in OPRM1 gene in opioid-exposed mother-infant dyads . Genes, Brain and Behavior 17:7, pages e12476.
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