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Research Paper

The chromatin remodeling protein Lsh alters nucleosome occupancy at putative enhancers and modulates binding of lineage specific transcription factors

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Pages 277-293 | Received 20 Sep 2018, Accepted 07 Feb 2019, Published online: 12 Mar 2019

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Maud De Dieuleveult, Martin Bizet, Laurence Colin, Emilie Calonne, Martin Bachman, Chao Li, Irina Stancheva, Benoit Miotto, François Fuks & Rachel Deplus. (2022) The chromatin remodelling protein LSH/HELLS regulates the amount and distribution of DNA hydroxymethylation in the genome. Epigenetics 17:4, pages 422-443.
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Xin Peng, Jingyue Sun, Yao Long, Desheng Xiao, Jianhua Zhou, Yongguang Tao & Shuang Liu. (2021) The Significance of HOXC11 and LSH in Survival Prediction in Gastric Adenocarcinoma. OncoTargets and Therapy 14, pages 1517-1529.
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Articles from other publishers (18)

Frédéric Berger, Kathrin Muegge & Eric J. Richards. (2023) Seminars in cell and development biology on histone variants remodelers of H2A variants associated with heterochromatin. Seminars in Cell & Developmental Biology 135, pages 93-101.
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Estanislao Peixoto, Asad Khan, Zachary A. Lewis, Rafael Contreras-Galindo & Wioletta Czaja. (2022) The Chromatin Remodeler HELLS: A New Regulator in DNA Repair, Genome Maintenance, and Cancer. International Journal of Molecular Sciences 23:16, pages 9313.
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Kai Ni & Kathrin Muegge. (2021) LSH catalyzes ATP-driven exchange of histone variants macroH2A1 and macroH2A2. Nucleic Acids Research 49:14, pages 8024-8036.
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Xiaoping Xu, Kai Ni, Yafeng He, Jianke Ren, Chongkui Sun, Yie Liu, Mirit I. Aladjem, Sandra Burkett, Richard Finney, Xia Ding, Shyam K. Sharan & Kathrin Muegge. (2021) The epigenetic regulator LSH maintains fork protection and genomic stability via MacroH2A deposition and RAD51 filament formation. Nature Communications 12:1.
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Alexandre Fagnan, Maria-Riera Piqué-BorràsSamantha TauchmannThomas Mercher & Juerg Schwaller. (2021) Molecular Landscapes and Models of Acute Erythroleukemia. HemaSphere 5:5, pages e558.
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Hesbon A Zablon, Chia-I Ko & Alvaro Puga. (2021) Converging Roles of the Aryl Hydrocarbon Receptor in Early Embryonic Development, Maintenance of Stemness, and Tissue Repair. Toxicological Sciences.
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Akihisa Osakabe, Bhagyshree Jamge, Elin Axelsson, Sean A. Montgomery, Svetlana Akimcheva, Annika Luisa Kuehn, Rahul Pisupati, Zdravko J. Lorković, Ramesh Yelagandula, Tetsuji Kakutani & Frédéric Berger. (2021) The chromatin remodeler DDM1 prevents transposon mobility through deposition of histone variant H2A.W. Nature Cell Biology 23:4, pages 391-400.
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Rui Yang, Gen Liu, Limin Han, Yuheng Qiu, Lulin Wang & Mei Wang. (2021) MiR-365a-3p-Mediated Regulation of HELLS/GLUT1 Axis Suppresses Aerobic Glycolysis and Gastric Cancer Growth. Frontiers in Oncology 11.
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Annalisa Tameni, Elisabetta Sauta, Valentina Mularoni, Federica Torricelli, Gloria Manzotti, Giorgio Inghirami, Riccardo Bellazzi, Valentina Fragliasso & Alessia Ciarrocchi. (2021) The DNA-helicase HELLS drives ALK− ALCL proliferation by the transcriptional control of a cytokinesis-related program. Cell Death & Disease 12:1.
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Kai Ni, Jianke Ren, Xiaoping Xu, Yafeng He, Richard Finney, Simon M. G. Braun, Nathaniel A. Hathaway, Gerald R. Crabtree & Kathrin Muegge. (2020) LSH mediates gene repression through macroH2A deposition. Nature Communications 11:1.
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Mei Yi, Yixin Tan, Li Wang, Jing Cai, Xiaoling Li, Zhaoyang Zeng, Wei Xiong, Guiyuan Li, Xiayu Li, Pingqing Tan & Bo Xiang. (2020) TP63 links chromatin remodeling and enhancer reprogramming to epidermal differentiation and squamous cell carcinoma development. Cellular and Molecular Life Sciences 77:21, pages 4325-4346.
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Yukiko Imai, Mathilde Biot, Julie AJ Clément, Mariko Teragaki, Serge Urbach, Thomas Robert, Frédéric Baudat, Corinne Grey & Bernard de Massy. (2020) PRDM9 activity depends on HELLS and promotes local 5-hydroxymethylcytosine enrichment. eLife 9.
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Shuxiong Wang, Michael L. Drummond, Christian F. Guerrero-Juarez, Eric Tarapore, Adam L. MacLean, Adam R. Stabell, Stephanie C. Wu, Guadalupe Gutierrez, Bao T. That, Claudia A. Benavente, Qing Nie & Scott X. Atwood. (2020) Single cell transcriptomics of human epidermis identifies basal stem cell transition states. Nature Communications 11:1.
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Yafeng HeJianke RenXiaoping XuKai NiAndrew SchwaderRichard FinneyCan WangLei SunKimberly KlarmannJonathan KellerAnthony Tubbs, Andre Nussenzweig & Kathrin Muegge. (2020) Lsh/HELLS is required for B lymphocyte development and immunoglobulin class switch recombination. Proceedings of the National Academy of Sciences 117:33, pages 20100-20108.
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Helmut Schiessel & Ralf Blossey. (2020) Pioneer transcription factors in chromatin remodeling: The kinetic proofreading view. Physical Review E 101:4.
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Gabriel Kollárovič, Caitríona E Topping, Edward P Shaw & Anna L Chambers. (2020) The human HELLS chromatin remodelling protein promotes end resection to facilitate homologous recombination and contributes to DSB repair within heterochromatin. Nucleic Acids Research 48:4, pages 1872-1885.
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Maja Vukic & Lucia Daxinger. (2019) DNA methylation in disease: Immunodeficiency, Centromeric instability, Facial anomalies syndrome. Essays in Biochemistry 63:6, pages 773-783.
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Ling Chen, Ying Shi, Na Liu, Zuli Wang, Rui Yang, Bin Yan, Xiaoli Liu, Weiwei Lai, Yating Liu, Desheng Xiao, Hu Zhou, Yan Cheng, Ya Cao, Shuang Liu, Zanxian Xia & Yongguang Tao. (2019) DNA methylation modifier LSH inhibits p53 ubiquitination and transactivates p53 to promote lipid metabolism. Epigenetics & Chromatin 12:1.
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